Successful medication withdrawal after cognitive-behavioral therapy in a treatment-resistant preadolescent male with obsessive-compulsive disorder.

Abstract:

:There are no reports of a child taking a selective serotonin reuptake inhibitor and an atypical anti-psychotic being successfully tapered from these medications after completion of cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder. With this in mind, we report the case of an 8.5-year-old male who was taking risperidone 0.5 mg bid, sertraline 100 mg, and atomoxetine 25 mg at presentation. After a successful course of CBT, we describe how medications were systematically withdrawn. Implications of this case on practice parameters (e.g., CBT may be an effective augmenting agent for those non-responsive to initial pharmacological treatments) are highlighted.

journal_name

Depress Anxiety

journal_title

Depression and anxiety

authors

Goldstein RB,Storch EA,Lehmkuhl H,Geffken GR,Goodman WK,Murphy TK

doi

10.1002/da.20448

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

E23-5

issue

1

eissn

1091-4269

issn

1520-6394

journal_volume

26

pub_type

信件
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    journal_title:Depression and anxiety

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    authors: Münsterkötter AL,Notzon S,Redlich R,Grotegerd D,Dohm K,Arolt V,Kugel H,Zwanzger P,Dannlowski U

    更新日期:2015-09-01 00:00:00

  • Cortisol awakening response in adolescents with acute sexual abuse related posttraumatic stress disorder.

    abstract:BACKGROUND:Little is known regarding changes in the hypothalamic-pituitary-adrenal axis (HPA axis) of adolescent girls with and without posttraumatic stress disorder (PTSD) who have recently experienced sexual abuse. Therefore, in this pilot study, we utilized non-stressed home saliva collection three times a day for t...

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    pub_type: 杂志文章

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    authors: Keeshin BR,Strawn JR,Out D,Granger DA,Putnam FW

    更新日期:2014-02-01 00:00:00

  • The role of values-consistent behavior in generalized anxiety disorder.

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    journal_title:Depression and anxiety

    pub_type: 杂志文章

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    authors: Michelson SE,Lee JK,Orsillo SM,Roemer L

    更新日期:2011-05-01 00:00:00

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    abstract:BACKGROUND:Although there has been abundant research on chronic low-grade inflammation as a potential mechanism underlying the link between mood disorders and cardiovascular risk, less is known about the role of inflammatory factors and anxiety disorders. The aim of this paper is to evaluate the bi-directional associat...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.22710

    authors: Glaus J,von Känel R,Lasserre AM,Strippoli MF,Vandeleur CL,Castelao E,Gholam-Rezaee M,Marangoni C,Wagner EN,Marques-Vidal P,Waeber G,Vollenweider P,Preisig M,Merikangas KR

    更新日期:2018-04-01 00:00:00

  • Subthreshold PTSD and PTSD in a prospective-longitudinal cohort of military personnel: Potential targets for preventive interventions.

    abstract:BACKGROUND:Prevention of PTSD requires identification of subpopulations contributing most to the population burden of PTSD. This study examines the relative contribution of subthreshold PTSD and probable PTSD on future PTSD in a representative military cohort. METHODS:We analyze data on 3,457 U.S. National Guard membe...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.22819

    authors: Fink DS,Gradus JL,Keyes KM,Calabrese JR,Liberzon I,Tamburrino MB,Cohen GH,Sampson L,Galea S

    更新日期:2018-11-01 00:00:00

  • Are SSRIs better than TCAs? Comparison of SSRIs and TCAs: a meta-analysis.

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    journal_title:Depression and anxiety

    pub_type: 杂志文章,meta分析

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    authors: Steffens DC,Krishnan KR,Helms MJ

    更新日期:1997-01-01 00:00:00

  • The efficacy of metacognitive therapy for anxiety and depression: a meta-analytic review.

    abstract:BACKGROUND:Metacognitive therapy (MCT) is a relatively new approach to treating mental disorders. The aim of the current meta-analysis was to examine the efficacy of MCT in patients with mental disorders. METHOD:A comprehensive literature search revealed 16 published as well as unpublished studies on the efficacy of M...

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    pub_type: 杂志文章,meta分析

    doi:10.1002/da.22273

    authors: Normann N,van Emmerik AA,Morina N

    更新日期:2014-05-01 00:00:00

  • Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study.

    abstract:BACKGROUND:Depression is a highly prevalent disease with a high morbidity and mortality risk. Its pathophysiology is not entirely clear. However, type 2 diabetes is an important risk factor for depression. One mechanism that may explain this association may include the formation of advanced glycation end products (AGEs...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.22527

    authors: van Dooren FE,Pouwer F,Schalkwijk CG,Sep SJ,Stehouwer CD,Henry RM,Dagnelie PC,Schaper NC,van der Kallen CJ,Koster A,Denollet J,Verhey FR,Schram MT

    更新日期:2017-01-01 00:00:00

  • Genetics of anxiety disorders: the complex road from DSM to DNA.

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    journal_title:Depression and anxiety

    pub_type: 杂志文章,评审

    doi:10.1002/da.20623

    authors: Smoller JW,Block SR,Young MM

    更新日期:2009-01-01 00:00:00

  • Changes in reported physical health symptoms and social function with prolonged exposure therapy for chronic posttraumatic stress disorder.

    abstract:BACKGROUND:Posttraumatic stress disorder (PTSD) is associated with significant health risk, illness, and functional impairment, e.g., Green and Kimerling [2004: Physical Health Consequences of Exposure to Extreme Stress. Washington, DC: American Psychological Association] Kimerling et al. [2000: Trauma and Health: J Tr...

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    pub_type: 杂志文章

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    authors: Rauch SA,Grunfeld TE,Yadin E,Cahill SP,Hembree E,Foa EB

    更新日期:2009-01-01 00:00:00

  • Adult mental health outcomes of adolescent depression: A systematic review.

    abstract:BACKGROUND:Adolescent depression may increase risk for poor mental health outcomes in adulthood. The objective of this study was to systematically review the literature on the association between adolescent depression and adult anxiety and depressive disorders as well as suicidality. METHODS:EMBASE, MEDLINE, and PSYCi...

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    authors: Johnson D,Dupuis G,Piche J,Clayborne Z,Colman I

    更新日期:2018-08-01 00:00:00

  • A biopsychosocial model as a guide for psychoeducation and treatment of depression.

    abstract::Effective treatment of severe or chronic unipolar depression requires the combination of pharmacological and psychotherapeutic interventions, and demands a theoretical paradigm integrating biological and psychosocial aspects of depression. Supported by recent research, we propose in our article a biopsychosocial diath...

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    pub_type: 杂志文章,评审

    doi:10.1002/da.20177

    authors: Schotte CK,Van Den Bossche B,De Doncker D,Claes S,Cosyns P

    更新日期:2006-01-01 00:00:00

  • Parental predictors of pediatric panic disorder/agoraphobia: a controlled study in high-risk offspring.

    abstract::Our objective was to evaluate parental risk factors for pediatric-onset panic disorder/agoraphobia (PD/AG) in offspring at high risk for PD/AG. Comparisons were made between parents with PD who had a child with PD or AG (N = 27) and parents with PD without children with PD or AG (N = 79). Comparisons were also made be...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.20122

    authors: Biederman J,Petty C,Faraone SV,Hirshfeld-Becker DR,Henin A,Dougherty M,Lebel TJ,Pollack M,Rosenbaum JF

    更新日期:2005-01-01 00:00:00

  • Physical activity offsets genetic risk for incident depression assessed via electronic health records in a biobank cohort study.

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    pub_type: 杂志文章

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    更新日期:2020-02-01 00:00:00

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    authors: Weller EB,Weller RA,Davis GP

    更新日期:2000-01-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1002/da.20269

    authors: Baños RM,Quero S,Botella C

    更新日期:2008-01-01 00:00:00

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    pub_type: 杂志文章,随机对照试验

    doi:10.1002/da.20147

    authors: Raedler TJ,Jahn H,Goedeken B,Gescher DM,Kellner M,Wiedemann K

    更新日期:2006-01-01 00:00:00

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    authors: Friedman MJ,Resick PA,Bryant RA,Strain J,Horowitz M,Spiegel D

    更新日期:2011-09-01 00:00:00

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    pub_type: 杂志文章,随机对照试验

    doi:10.1002/da.20520

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    更新日期:2009-01-01 00:00:00

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    abstract:BACKGROUND:The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive. METHODS:Using ...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.22379

    authors: Pattyn T,Van Den Eede F,Lamers F,Veltman D,Sabbe BG,Penninx BW

    更新日期:2015-07-01 00:00:00

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    journal_title:Depression and anxiety

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/da.22029

    authors: Bui E,Simon NM,Robinaugh DJ,Leblanc NJ,Wang Y,Skritskaya NA,Mauro C,Shear MK

    更新日期:2013-02-01 00:00:00

  • A placebo-controlled pilot study of a wearable morning bright light treatment for probable PTSD.

    abstract:BACKGROUND:Evidence-based treatments for post-traumatic stress disorder (PTSD) have poor uptake and remission rates, suggesting that alternative treatments are needed. Morning bright light may be an effective treatment for PTSD given its established effects on mood and sleep, however, there are no published trials. ME...

    journal_title:Depression and anxiety

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/da.22897

    authors: Zalta AK,Bravo K,Valdespino-Hayden Z,Pollack MH,Burgess HJ

    更新日期:2019-07-01 00:00:00

  • The relationship between major depression and marital disruption is bidirectional.

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    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.20618

    authors: Bulloch AG,Williams JV,Lavorato DH,Patten SB

    更新日期:2009-01-01 00:00:00

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    abstract:BACKGROUND:The present trial was designed to assess the efficacy and safety of escitalopram prescribed to patients seeking treatment of major depressive disorder (MDD) in a Canadian primary-care setting. METHODS:Investigators (mainly primary-care physicians) enrolled patients with MDD from their daily practice. Patien...

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    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/da.20458

    authors: Chokka P,Legault M

    更新日期:2008-01-01 00:00:00

  • Anxiolytic effect and memory improvement in rats by antisense oligodeoxynucleotide to 5-hydroxytryptamine-2A precursor protein.

    abstract::Serotonergic (5-hydroxytryptamine; 5-HT) mechanisms have been implicated in a number of physiological and pathophysiological processes including mood, anxiety, and cognitive functioning. Among the many 5-HT receptor subtypes, the 5-HT2A receptors (5-HT2A-R) seem to be of particular importance in mediating these effect...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.20087

    authors: Cohen H

    更新日期:2005-01-01 00:00:00

  • EEG effects of ECT: implications for rTMS.

    abstract::Electroconvulsive therapy (ECT) involves the use of electrical stimulation to elicit a series of generalized tonic-clonic seizures for therapeutic purposes and is the most effective treatment known for major depression. These treatments have significant neurophysiologic effects, many of which are manifest in the elect...

    journal_title:Depression and anxiety

    pub_type: 杂志文章,评审

    doi:10.1002/1520-6394(2000)12:3<157::AID-DA7>3.0.CO;2-

    authors: Krystal AD,West M,Prado R,Greenside H,Zoldi S,Weiner RD

    更新日期:2000-01-01 00:00:00

  • Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: A 2-week ambulatory assessment study.

    abstract:BACKGROUND:Actigraphy may provide a more valid assessment of sleep, circadian rhythm (CR), and physical activity (PA) than self-reported questionnaires, but has not been used widely to study the association with depression/anxiety and their clinical characteristics. METHODS:Fourteen-day actigraphy data of 359 particip...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.22949

    authors: Difrancesco S,Lamers F,Riese H,Merikangas KR,Beekman ATF,van Hemert AM,Schoevers RA,Penninx BWJH

    更新日期:2019-10-01 00:00:00

  • Unguided Internet-based cognitive-behavioral therapy for obsessive-compulsive disorder: A randomized controlled trial.

    abstract:BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...

    journal_title:Depression and anxiety

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/da.23105

    authors: Schröder J,Werkle N,Cludius B,Jelinek L,Moritz S,Westermann S

    更新日期:2020-12-01 00:00:00

  • Are obsessive-compulsive symptom dimensions familial in nonclinical individuals?

    abstract:BACKGROUND:Obsessive-compulsive disorder (OCD) is a heterogeneous condition, which can be expressed as various potentially overlapping symptom dimensions. In clinical samples, some of these dimensions are associated with increased familial risk for OCD and appear to be familial (intercorrelated within pairs of affected...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.20606

    authors: Taberner J,Fullana MA,Caseras X,Pertusa A,Bados A,van den Bree M,Torrubia R,Mataix-Cols D

    更新日期:2009-01-01 00:00:00

  • Generalized social phobia and avoidant personality disorder: meaningful distinction or useless duplication?

    abstract::Participants with generalized social phobia (GSP) with (n=36) and without (n=19) avoidant personality disorder (AVPD) were compared via contrasts of group means and classification analysis on purported core features of AVPD. GSP-AVPD participants proved to be more severely impaired or distressed on some group contrast...

    journal_title:Depression and anxiety

    pub_type: 杂志文章

    doi:10.1002/da.20266

    authors: Chambless DL,Fydrich T,Rodebaugh TL

    更新日期:2008-01-01 00:00:00