Abstract:
BACKGROUND:Evidence-based treatments for post-traumatic stress disorder (PTSD) have poor uptake and remission rates, suggesting that alternative treatments are needed. Morning bright light may be an effective treatment for PTSD given its established effects on mood and sleep, however, there are no published trials. METHODS:We conducted a placebo-controlled pilot trial of a wearable light device, the Re-timer®, for individuals with probable PTSD. Individuals were randomly assigned to the active Re-timer® (n = 9) or a placebo Re-timer® dimmed with neutral density filters (n = 6). Participants self-administered the treatment at home 1 hr each morning over 4 weeks. PTSD and depression symptoms were assessed at pre- and post-treatment. RESULTS:The Re-timer® was well tolerated and the perceived benefit was high, though treatment adherence was only moderate. Those in the active group were more likely to achieve a minimal clinically important change in PTSD and depression symptoms and had larger symptom reductions than those in the placebo group CONCLUSIONS: A wearable morning light treatment was acceptable and feasible for patients with probable PTSD. This study provides initial proof-of-concept that light treatment can improve PTSD. A larger trial is warranted to establish treatment efficacy. NCT#: 03513848.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Zalta AK,Bravo K,Valdespino-Hayden Z,Pollack MH,Burgess HJdoi
10.1002/da.22897subject
Has Abstractpub_date
2019-07-01 00:00:00pages
617-624issue
7eissn
1091-4269issn
1520-6394journal_volume
36pub_type
杂志文章,随机对照试验abstract::We successfully treated a 46-year-old narcoleptic woman suffering from atypical depression with bupropion hydrochloride. Diagnostic evaluation revealed a Beck Depression Inventory (BDI) score of 24, a short nocturnal REM-sleep latency, subjective and objective sleepiness (mean sleep latency (MSL) = 1.8 minutes), and t...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Electroconvulsive therapy (ECT) involves the use of electrical stimulation to elicit a series of generalized tonic-clonic seizures for therapeutic purposes and is the most effective treatment known for major depression. These treatments have significant neurophysiologic effects, many of which are manifest in the elect...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/1520-6394(2000)12:3<157::AID-DA7>3.0.CO;2-
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Little is known about the association between trauma exposure and suicidal ideation across racial/ethnic groups. Our study aim was to determine the association between trauma exposure and suicidal ideation in a nationally representative ethnically diverse sample of adults. METHODS:This study included 14,866...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22485
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Adolescent depression may increase risk for poor mental health outcomes in adulthood. The objective of this study was to systematically review the literature on the association between adolescent depression and adult anxiety and depressive disorders as well as suicidality. METHODS:EMBASE, MEDLINE, and PSYCi...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.22777
更新日期:2018-08-01 00:00:00
abstract::The chronicity and morbidity of established post-traumatic stress disorder (PTSD) has stimulated interest in recognizing and understanding the early development of the disorder. Acute stress disorder, a new diagnosis intended to facilitate early case detection, rests on the occurrence of dissociative reactions. It rem...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.1071
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explor...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22672
更新日期:2017-11-01 00:00:00
abstract::There are well-established sex differences in the prevalence of certain mental disorders. Work in animal models has provided us with an emerging understanding of the role that epigenetic factors play in establishing sex differences in the brain during development. Similarly, work in animal models, and a more limited b...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.22167
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:An issue of critical importance for psychiatry and women's health is whether postpartum depression (PPD) represents a unique condition. The Diagnostic and Statistical Manual of Mental Disorders asserts that major depressive disorder (MDD) may present with peripartum onset, without suggesting any other differ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22719
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Accumulating evidence suggests that posttraumatic stress disorder (PTSD) is associated with disrupted default mode network (DMN) connectivity, but findings across studies have not been uniform. Individual differences in relevant genes may account for some of the reported variability in the relationship betwe...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22633
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Panic disorder (PD) is highly comorbid with major depressive disorder (MDD) with potential impact on patient-reported outcomes of quality of life (QOL), functioning, and depressive symptom severity. METHODS:Using data from the sequenced treatment alternatives to relieve depression (STAR*D) trial, we compare...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/da.22152
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Anticipatory anxiety can be described as a conditioned response with a defensive posture of freezing and autonomic activation. The purpose of this study was to assess the postural control analysis and autonomic activation in panic disorder (PD) patients presented with visual stimuli. METHODS:PD patients (n=...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20593
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Parental mental disorders have been shown to predict offspring's mental health problems. We examined whether pathways from parental mental disorders to offspring's psychiatric work disability in early adulthood are mediated through offspring's mental disorders and social disadvantage in adolescence. METHODS...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22847
更新日期:2019-04-01 00:00:00
abstract::Clinical commentators widely interpret crying as a sign of depressed mood. However, there is virtually no empirical data on this topic, and the evidence that mood disorders alter crying is surprisingly weak. This study compared mood disordered patients to a nonpsychiatric reference group on the frequency, antecedents,...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20331
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Anxiety symptoms are common in adolescence and are often considered developmentally benign. Yet for some, anxiety presents with serious comorbid nonanxiety psychopathology. Early identification of such "malignant" anxiety presentations is a major challenge. We aimed to characterize anxiety symptoms suggestiv...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23060
更新日期:2020-09-01 00:00:00
abstract::This study seeks to determine how panic disorder patients with anxiety and depression comorbidity differ from panic disorder patients without comorbidity at the time of presentation for treatment. One-hundred seventy-one panic disorder patients presenting for their initial assessment and treatment at the Payne Whitney...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/1520-6394(2000)12:2<78::AID-DA3>3.0.CO;2-5
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Diagnostic criteria for DSM-5 posttraumatic stress disorder (PTSD) are in many ways similar to DSM-IV criteria, raising the possibility that it might be possible to closely approximate DSM-5 diagnoses using DSM-IV symptoms. If so, the resulting transformation rules could be used to pool research data based o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22364
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Controversy surrounds the question of whether agoraphobia (AG) exists as an independent diagnostic entity apart from panic. In favor of this position, AG without panic disorder (PD) in parents was found being unrelated to offsprings' risk for AG or PD, albeit it may enhance the familial transmission of PD (N...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21975
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20612
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Women are at an increased risk of depression and other mental health problems following rape. Various etiological factors for depression, including predisposing genetic factors, have been identified. Telomeres are repetitive nucleoprotein structures located at chromosomal ends that protect them from prematur...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20903
更新日期:2011-12-21 00:00:00
abstract:BACKGROUND:To examine the potential mediating role of parenting behaviors in the longitudinal, bidirectional relationships between maternal depression and child internalizing symptoms (i.e. depression and anxiety). METHODS:We analyzed data from 4,581 mother-child dyads from the Fragile Families and Child Wellbeing Stu...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22688
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Maintenance of gains with cognitive-behavioral treatment for trichotillomania (TTM) has historically been problematic. METHODS:We conducted follow-up assessments 3 and 6 months after completion of a 3-month maintenance phase on 10 individuals with DSM-IV-TR TTM who participated in an open trial of a dialect...
journal_title:Depression and anxiety
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/da.20778
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Internet-delivered cognitive behavioral therapy (iCBT) is a relatively novel treatment method that may improve the accessibility of mental health care for individuals with posttraumatic stress disorder (PTSD). The aim of this meta-analysis was to evaluate the effectiveness of iCBT compared to inactive (waitl...
journal_title:Depression and anxiety
pub_type: 杂志文章,meta分析,评审
doi:10.1002/da.22533
更新日期:2016-09-01 00:00:00
abstract::Research has shown that obsessive compulsive disorder (OCD) is related to structural and functional abnormalities in the brain, and several authors have organized these findings into theories of OCD neuropsychiatric dysfunction. In this paper, these theories were used to develop a neural network model of OCD. OCD symp...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1998)8:3<91::aid-da1>3.0.c
更新日期:1998-01-01 00:00:00
abstract::Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/(sici)1520-6394(1997)5:3<115::aid-da1>3.0.
更新日期:1997-01-01 00:00:00
abstract::In spite of substantial advances in the treatment of major depression by pharmacotherapy and other means, a significant number of depressed patients require hospitalization. In the context of the Jerusalem Collaborative Depression Project, possible precipitants of psychiatric hospitalization were sought in a cohort of...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Disrupted sensory filtering, or problems with suppressing irrelevant environmental sensory stimuli, has been reported in individuals with posttraumatic stress disorder (PTSD). However, the relationship of sensory filtering deficits to specific PTSD symptoms versus an association with general trauma exposure is unclear...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20255
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23101
更新日期:2020-10-14 00:00:00
abstract:BACKGROUND:There is ample evidence of the efficacy of cognitive-behavioral therapy (CBT) for depression in adolescents, including Puerto Rican adolescents. However, there is still a high percentage of adolescents who do not respond to a standard "dose" of 12 sessions of CBT. This clinical case study explores the charac...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20457
更新日期:2009-01-01 00:00:00
abstract::This study examined the 3-year outcome of major depression (MD)/dysthymic disorder (DD), minor depression (MinD), and subsyndromal symptomatic depression (SSD) in a population-based sample. The aims were to study the fluctuating nature of the symptoms of depression and to analyze the risk of fulfilling the criteria fo...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20231
更新日期:2007-01-01 00:00:00
abstract::The purpose of this study was to correlate subjective sleep characteristics based on questionnaire response, and objective sleep EEG features based on polysomnography, in 52 patients with major depressive disorders (MDD) and 49 healthy controls. With the exception of the number of awakenings, subjective and objective ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1997)5:2<97::aid-da6>3.0.c
更新日期:1997-01-01 00:00:00