Abstract:
BACKGROUND:Theory and research suggest that generalized anxiety disorder (GAD) is associated with diminished quality of life and restriction in valued action. The purpose of this study was to examine the relevance of values-consistent behavior (valued action) in understanding the impairment in quality of life in GAD. METHOD:Treatment-seeking clients with a principal diagnosis of GAD (n = 30) were compared with demographically matched nonanxious controls (n = 30) using self-report measures. RESULTS:Participants with GAD reported significantly less valued action compared with controls, and within the GAD group, diminished valued action was not fully explained by depression comorbidity. Valued action was significantly correlated with measures of experiential avoidance, distress about emotions, and quality of life. Further, consistent with a theoretical model of GAD, restrictions in valued action contributed unique variance to diminished quality of life over and above the contributions of gender, GAD severity, experiential avoidance, distress about emotions, and depression comorbidity. Finally, an acceptance-based behavioral therapy significantly improved self-reports of valued action for GAD clients with 40% achieving clinically significant change in this domain. CONCLUSION:The findings provide preliminary support for the relevance of valued action in understanding the functional impairment associated with GAD, and the beneficial effects of an acceptance-based behavior therapy in increasing valued action.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Michelson SE,Lee JK,Orsillo SM,Roemer Ldoi
10.1002/da.20793subject
Has Abstractpub_date
2011-05-01 00:00:00pages
358-66issue
5eissn
1091-4269issn
1520-6394journal_volume
28pub_type
杂志文章abstract::Participants with generalized social phobia (GSP) with (n=36) and without (n=19) avoidant personality disorder (AVPD) were compared via contrasts of group means and classification analysis on purported core features of AVPD. GSP-AVPD participants proved to be more severely impaired or distressed on some group contrast...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20266
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Anxiety symptoms are common in adolescence and are often considered developmentally benign. Yet for some, anxiety presents with serious comorbid nonanxiety psychopathology. Early identification of such "malignant" anxiety presentations is a major challenge. We aimed to characterize anxiety symptoms suggestiv...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23060
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Exposure therapy, a gold-standard treatment for anxiety disorders, is assumed to work via extinction learning, but this has never been tested. Anxious individuals demonstrate extinction learning deficits, likely related to less ventromedial prefrontal cortex (vmPFC) and more amygdala activation, but the rela...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22583
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Hypothalamic-pituitary-adrenal (HPA) axis functioning has been implicated in the development of stress-related psychiatric diagnoses and response to adverse life experiences. This study aimed to investigate the association between genetic and epigenetics in HPA axis and response to cognitive behavior therapy...
journal_title:Depression and anxiety
pub_type: 杂志文章,多中心研究
doi:10.1002/da.22430
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Psychosocial factors, including religious coping, consistently have been implicated in the expression of anxiety disorders. This study sought to investigate the relationship between religious coping on anxiety symptoms among a nonclinical sample of African American and European American young adults. METHOD...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20510
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Bipolar disorder (BD) is highly familial, but studies have yet to examine preschoolers at risk for BD using standardized, developmentally appropriate clinical assessment tools. We used such methods to test whether preschoolers at familial risk for BD have more observed difficulty modulating emotions and beha...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22342
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Amygdala-prefrontal cortex (PFC) functional connectivity may be influenced by anxiety and development. A prior study on anxiety found age-specific dysfunction in the ventromedial PFC (vmPFC), but not amygdala, associated with threat-safety discrimination during extinction recall (Britton et al.). However, tr...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22470
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Brain structures underlying posttraumatic stress disorder (PTSD) have been a focus of imaging studies, but associations between treatment outcome and alterations in brain structures remain largely unexamined. We longitudinally examined the relation of structural changes in the rostral anterior cingulate cort...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22471
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Social anxiety disorder (SAD) is an incapacitating disorder running in families. Previous work associated social fearfulness with a failure to habituate, but the habituation response to neutral faces has, as of yet, not been investigated in patients with SAD and their family members concurrently. Here, we ex...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22962
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:In this study, we examined executive control of attention in individuals with contamination-related obsessive-compulsive (OC) symptoms using a modified version of the Eriksen flanker task. The task indexes one's ability to resolve attentional conflict between different responses and to ignore task distracter...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20703
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive. METHODS:Using ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22379
更新日期:2015-07-01 00:00:00
abstract::The diagnosis of anxiety disorders and major depression can be reliably made based on signs and symptoms. However there are significant limitations to the current system of classification including overlapping criteria, high comorbidity, and the issue of subthreshold syndromes. The literature on treatment response doc...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.1049
更新日期:2001-01-01 00:00:00
abstract::Data from early studies of selective serotonin reuptake inhibitors have shown that these agents are effective in the treatment of social anxiety disorder (social phobia). This review highlights the outcomes of three large clinical trials of paroxetine in patients with social anxiety disorder. In two of the studies, pa...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Parental mental disorders have been shown to predict offspring's mental health problems. We examined whether pathways from parental mental disorders to offspring's psychiatric work disability in early adulthood are mediated through offspring's mental disorders and social disadvantage in adolescence. METHODS...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22847
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Evidence-based treatments for post-traumatic stress disorder (PTSD) have poor uptake and remission rates, suggesting that alternative treatments are needed. Morning bright light may be an effective treatment for PTSD given its established effects on mood and sleep, however, there are no published trials. ME...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22897
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of c...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22683
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Dimensional assessments are planned to be included as supplements to categorical diagnoses in DSM-V. The aim of this study was to examine the unidimensionality, reliability, validity, and clinical sensitivity of brief self-rated scales for specific anxiety disorders in an unselected German sample of consecut...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21994
更新日期:2012-12-01 00:00:00
abstract::This study examined sex differences in the use of coping strategies and their relationship to depression and anxiety-related psychopathology. Responses on measures of coping strategies, depression, and anxiety were obtained from a carefully screened nonclinical sample (N = 107). The results demonstrated that women who...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20341
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20612
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Smoking in patients with bipolar disorder is known to be related to suicidality. This link has not been investigated, however, in community-based samples. The aim of this study is to delineate the sociodemographic and clinical characteristics of bipolar smokers and examine the relationship between these char...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22107
更新日期:2013-10-01 00:00:00
abstract::The objective was to present naturalistic 1-year follow-up information of 96 child and adolescent outpatients with major depressive disorder who had been randomized in an 8-week double-blind, placebo-controlled trial of fluoxetine. Subjects were children and adolescents, ages 8-18 years, who were entered in a randomiz...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/(sici)1520-6394(1998)7:1<32::aid-da4>3.0.c
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Previous studies have indicated a high prevalence of generalized anxiety disorder (GAD) in women with anorexia nervosa (AN). However, the shared genetic and environmental components of these disorders have not been explored. This study seeks to elucidate the shared genetic and environmental components betwee...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20834
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The present trial was designed to assess the efficacy and safety of escitalopram prescribed to patients seeking treatment of major depressive disorder (MDD) in a Canadian primary-care setting. METHODS:Investigators (mainly primary-care physicians) enrolled patients with MDD from their daily practice. Patien...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/da.20458
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22394
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Anticipatory anxiety can be described as a conditioned response with a defensive posture of freezing and autonomic activation. The purpose of this study was to assess the postural control analysis and autonomic activation in panic disorder (PD) patients presented with visual stimuli. METHODS:PD patients (n=...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20593
更新日期:2009-01-01 00:00:00
abstract::Because of their high comorbidity and strong associations, the distinctiveness of anxiety and depression in youth continues to be debated. In this study we used cluster analysis in a community sample (n=225) of youth to test tripartite model predictions regarding the grouping of individuals based on their levels of an...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20215
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Reducing access to lethal means (especially firearms) might prevent suicide, but counseling of at-risk individuals about this strategy may not be routine. Among emergency department (ED) patients with suicidal ideation or attempts (SI/SA), we sought to describe home firearm access and examine ED provider ass...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22486
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Individuals with depression may not seek treatment for their symptoms due to several types of barriers to treatment. In support of the growing research on mental health care access and the role of social media, this study aimed to increase knowledge of these barriers among social media users. METHODS:Partic...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22990
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light thera...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22739
更新日期:2018-05-01 00:00:00
abstract::Paruresis is characterized by the fear of not being able to urinate in public bathrooms and has been classified by some to be a sub-type of social anxiety disorder (social phobia). Despite the existence of a consumer advocacy organization, the "Intentional Paruresis Association (www.paruresis.org)," there is sparse li...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.10061
更新日期:2002-01-01 00:00:00