Decreased striatal D1 binding as measured using PET and [11C]SCH 23,390 in patients with major depression with anger attacks.

abstract：BACKGROUND:Controversy surrounds the question of whether agoraphobia (AG) exists as an independent diagnostic entity apart from panic. In favor of this position, AG without panic disorder (PD) in parents was found being unrelated to offsprings' risk for AG or PD, albeit it may enhance the familial transmission of PD (N...

journal_title：Depression and anxiety

authors： Knappe S,Beesdo-Baum K,Nocon A,Wittchen HU

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:A pooled analysis was performed on data from two studies evaluating the efficacy of once-daily extended-release quetiapine fumarate (quetiapine XR) monotherapy for patients with major depressive disorder. Through these analyses (based on Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale ...

journal_title：Depression and anxiety

authors： Thase ME,Demyttenaere K,Earley WR,Gustafsson U,Udd M,Eriksson H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:A history of past major depressive episodes (MDEs) is known to be a risk factor for future MDEs. Additional information about the relationship between past and future episodes would be useful in clinical practice, it is therefore important to fully understand the epidemiology of major depression. We asked wh...

journal_title：Depression and anxiety

authors： Bulloch A,Williams J,Lavorato D,Patten S

更新日期：2014-01-01 00:00:00

abstract：:Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...

journal_title：Depression and anxiety

authors： Chang SC

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...

journal_title：Depression and anxiety

authors： Ollmann TM,Voss C,Venz J,Seidl E,Hoyer J,Kische H,Pieper L,Schiele MA,Domschke K,Beesdo-Baum K

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Individuals with depression may not seek treatment for their symptoms due to several types of barriers to treatment. In support of the growing research on mental health care access and the role of social media, this study aimed to increase knowledge of these barriers among social media users. METHODS:Partic...

journal_title：Depression and anxiety

authors： Szlyk H,Deng J,Xu C,Krauss MJ,Cavazos-Rehg PA

更新日期：2020-05-01 00:00:00

abstract：:Serotonergic (5-hydroxytryptamine; 5-HT) mechanisms have been implicated in a number of physiological and pathophysiological processes including mood, anxiety, and cognitive functioning. Among the many 5-HT receptor subtypes, the 5-HT2A receptors (5-HT2A-R) seem to be of particular importance in mediating these effect...

journal_title：Depression and anxiety

authors： Cohen H

更新日期：2005-01-01 00:00:00

abstract：:This study examined the validity of the Assessment of Depression Inventory (ADI), a 39-item measure of depression with three embedded validity scales, using inpatient participants. The ADI Depression (Dep) and Feigning (Fg) scales were compared to the corresponding scales of a widely used multiscale instrument, the Pe...

journal_title：Depression and anxiety

authors： Mogge NL

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Although numerous studies have examined the role of latent predispositions to internalizing and externalizing disorders in the structure of comorbidity among common mental disorders, none examined latent predispositions in predicting development of comorbidity. METHODS:A novel method was used to study the r...

journal_title：Depression and anxiety

authors： Kessler RC,Cox BJ,Green JG,Ormel J,McLaughlin KA,Merikangas KR,Petukhova M,Pine DS,Russo LJ,Swendsen J,Wittchen HU,Zaslavsky AM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Physical activity is increasingly recognized as an important modifiable factor for depression. However, the extent to which individuals with stable risk factors for depression, such as high genetic vulnerability, can benefit from the protective effects of physical activity, remains unknown. Using a longitudi...

journal_title：Depression and anxiety

authors： Choi KW,Zheutlin AB,Karlson RA,Wang MJ,Dunn EC,Stein MB,Karlson EW,Smoller JW

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Recent research suggests that posttraumatic stress disorder (PTSD) is associated with altered amygdala and hippocampal resting-state functional connectivity (rsFC). However, less research has examined whether Prolonged Exposure (PE), a first line exposure-based treatment for PTSD, has the potential to alter ...

journal_title：Depression and anxiety

authors： Zhu X,Suarez-Jimenez B,Lazarov A,Helpman L,Papini S,Lowell A,Durosky A,Lindquist MA,Markowitz JC,Schneier F,Wager TD,Neria Y

更新日期：2018-10-01 00:00:00

abstract：:This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week open-label study of f...

journal_title：Depression and anxiety

authors： Escalona R,Canive JM,Calais LA,Davidson JR

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Smoking in patients with bipolar disorder is known to be related to suicidality. This link has not been investigated, however, in community-based samples. The aim of this study is to delineate the sociodemographic and clinical characteristics of bipolar smokers and examine the relationship between these char...

journal_title：Depression and anxiety

authors： Baek JH,Eisner LR,Nierenberg AA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Depression and anxiety have been related to poorer self-reported physical functioning over time; however, objective measures of physical function are less frequently examined. This study assessed the 6-year trajectory of hand-grip strength and lung function in persons with depressive and/or anxiety disorders...

journal_title：Depression and anxiety

authors： Lever-van Milligen BA,Lamers F,Smit JH,Penninx BW

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Comorbid psychiatric disorders, cardiovascular disease, chronic hypertension, diabetes, and musculoskeletal disorders are highly prevalent in depression. However, the extent to which these conditions affect the recurrence of depression-related work disability is unknown. The specific aims of the study were t...

journal_title：Depression and anxiety

authors： Ervasti J,Vahtera J,Pentti J,Oksanen T,Ahola K,Kivekäs T,Kivimäki M,Virtanen M

更新日期：2014-09-01 00:00:00

abstract：:Given the high rates of maladjustment among children of depressed mothers, parenting is likely to cause significant life stress in this population, potentially worsening the course of mothers' depression. The present study is a comparison of severe life stress in 38 mothers and 62 non-mothers receiving treatment for r...

journal_title：Depression and anxiety

authors： Feske U,Shear MK,Anderson B,Cyranowski J,Strassburger M,Matty M,Luther J,Frank E

更新日期：2001-01-01 00:00:00

abstract：:The current study describes the validation of a new cognitive assessment measure for social phobia, entitled the Appraisal of Social Concerns (ASC). Item content is relevant to a range of social situations. The ASC can be used to tailor interventions to patients' idiosyncratic concerns. Data are presented from both cl...

journal_title：Depression and anxiety

authors： Telch MJ,Lucas RA,Smits JA,Powers MB,Heimberg R,Hart T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Irritability is prevalent and impairing in pediatric bipolar disorder (BD) but has been minimally studied using neuroimaging techniques. We used magnetoencephalography (MEG) to study theta band oscillations in the anterior cingulate cortex (ACC) during frustration in BD youth. ACC theta power is associated w...

journal_title：Depression and anxiety

authors： Rich BA,Holroyd T,Carver FW,Onelio LM,Mendoza JK,Cornwell BR,Fox NA,Pine DS,Coppola R,Leibenluft E

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Fear overgeneralization is a central feature of anxiety disorders and can lead to excessive avoidance. As perceptual discrimination is a key component of fear overgeneralization, a perceptual discrimination training task was created aimed at improving perceptual discrimination and reducing fear overgeneraliz...

journal_title：Depression and anxiety

authors： Ginat-Frolich R,Klein Z,Aderka IM,Shechner T

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome characterized by traumatic and separation distress lasting over 6 months. Little is known about the role of dissociation experienced during or immediately after the loss of a loved one (i.e., periloss dissociation [PLD]) in CG. The present study aimed...

journal_title：Depression and anxiety

authors： Bui E,Simon NM,Robinaugh DJ,Leblanc NJ,Wang Y,Skritskaya NA,Mauro C,Shear MK

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Although a large body of empirical research has examined negative psychological outcomes in older veterans, relatively little is known about the prevalence and determinants of psychological resilience in this population. METHODS:A nationally representative sample of 2,025 U.S. veterans aged 60 and older (me...

journal_title：Depression and anxiety

authors： Pietrzak RH,Cook JM

更新日期：2013-05-01 00:00:00

abstract：:This study replicated the factor structure of the Parental Bonding Instrument (PBI), and explored the relationships of PBI scores to demographic variables. We investigated the association between parental bonding in the parents measured by the PBI, and lifetime history of depression in their children assessed by the I...

journal_title：Depression and anxiety

authors： Uehara T,Sato T,Sakado K,Someya T

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:A significant proportion of soldiers return from deployment with symptoms of fatigue, sleep difficulties, and posttraumatic complaints. Disrupted sleep has been proposed as a contributing factor for the development of posttraumatic stress disorder (PTSD). This study investigates the impact of impaired sleep ...

journal_title：Depression and anxiety

authors： van Liempt S,van Zuiden M,Westenberg H,Super A,Vermetten E

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Although diagnostically dissociable, anxiety is strongly co-morbid with depression. To examine further the clinical symptoms of anxiety in major depressive disorder (MDD), a non-parametric item response analysis on "blinded" data from four pharmaceutical company clinical trials was performed on the Hamilton ...

journal_title：Depression and anxiety

authors： Vaccarino AL,Evans KR,Sills TL,Kalali AH

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Dimensional assessments are planned to be included as supplements to categorical diagnoses in DSM-V. The aim of this study was to examine the unidimensionality, reliability, validity, and clinical sensitivity of brief self-rated scales for specific anxiety disorders in an unselected German sample of consecut...

journal_title：Depression and anxiety

authors： Beesdo-Baum K,Klotsche J,Knappe S,Craske MG,Lebeau RT,Hoyer J,Strobel A,Pieper L,Wittchen HU

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that posttraumatic stress disorder (PTSD) is associated with disrupted default mode network (DMN) connectivity, but findings across studies have not been uniform. Individual differences in relevant genes may account for some of the reported variability in the relationship betwe...

journal_title：Depression and anxiety

authors： Miller DR,Logue MW,Wolf EJ,Maniates H,Robinson ME,Hayes JP,Stone A,Schichman S,McGlinchey RE,Milberg WP,Miller MW

更新日期：2017-07-01 00:00:00

abstract：:The chronicity and morbidity of established post-traumatic stress disorder (PTSD) has stimulated interest in recognizing and understanding the early development of the disorder. Acute stress disorder, a new diagnosis intended to facilitate early case detection, rests on the occurrence of dissociative reactions. It rem...

journal_title：Depression and anxiety

authors： Mellman TA,David D,Bustamante V,Fins AI,Esposito K

更新日期：2001-01-01 00:00:00

abstract：:Ninety-three patients, including 47 patients with Generalized Anxiety Disorder (GAD) and 46 patients with Major Depression (MD), were entered into recent clinical trials. Clinicians acknowledge that during the initial screening process, clear separation between depressed and anxious patients may be difficult. By using...

journal_title：Depression and anxiety

authors： Freeman AM 3rd,Kablinger AS,Rolland PD,Brannon GE

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Depression outcomes in research and clinical practice are commonly defined by the concepts of remission, recovery, relapse, and recurrence. Despite their widespread use, there has been little empirical examination of these concepts. Therefore, we investigated profiles of individual symptoms during each of th...

journal_title：Depression and anxiety

authors： Conradi HJ,Ormel J,de Jonge P

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Patients with obsessive-compulsive disorder (OCD) experience abnormally high levels of uncertainty, and unpredictability is evaluated negatively and not well tolerated. The current study examined neural correlates of attentional processing in response to experimentally induced uncertainty in OCD. METHODS:Tw...

journal_title：Depression and anxiety

authors： Dieterich R,Endrass T,Kathmann N

更新日期：2017-11-01 00:00:00