Exposure-based therapy changes amygdala and hippocampus resting-state functional connectivity in patients with posttraumatic stress disorder.

abstract：:Internet-delivered cognitive behavioral therapy (iCBT) was developed to overcome some of the barriers in accessing best practice face-to-face CBT. iCBT affords many benefits, such as high fidelity, greater accessibility, convenience, and reduced cost to patients and health-care systems. Recent meta-analyses of iCBT fo...

journal_title：Depression and anxiety

authors： Andrews G,Williams AD

更新日期：2014-11-01 00:00:00

abstract：:An impediment to progress in mood disorders research is the lack of analytically valid and qualified diagnostic and treatment biomarkers. Consistent with the National Institute of Mental Health (NIMH)'s Research Domain Criteria (RDoC) initiative, the lack of diagnostic biomarkers has precluded us from moving away from...

journal_title：Depression and anxiety

authors： Niciu MJ,Mathews DC,Nugent AC,Ionescu DF,Furey ML,Richards EM,Machado-Vieira R,Zarate CA Jr

更新日期：2014-04-01 00:00:00

abstract：:The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the treatment of depressi...

journal_title：Depression and anxiety

authors： Lee S,Walker JR,Jakul L,Sexton K

更新日期：2004-01-01 00:00:00

abstract：:The selective serotonin reuptake inhibitors (SSRIs) are recognized as effective as and better tolerated than older antidepressant therapies and have become the drugs of choice in the treatment of mild to moderate depression. However, there is a clinical impression that the SSRIs are less effective than older therapies...

journal_title：Depression and anxiety

authors： Schatzberg AF

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To examine (1) clinically relevant anxiety with comorbid depression in an older population, and the presentation of subthreshold symptoms; (2) to assess anxiety and levels of comorbid depression associated with migration, religion, loneliness and long-term illness. METHODS:Analysis of Wave 1 of The Irish Lon...

journal_title：Depression and anxiety

authors： Curran E,Rosato M,Cooper J,Mc Garrigle CA,Leavey G

更新日期：2019-09-01 00:00:00

abstract：:This study sought to describe clinical and demographic characteristics differentiating patients with DSM-III-R simple phobias comorbid with one or more of five DSM-III-R index anxiety disorders as compared with those with the index diagnoses alone. From 711 subjects participating in a multicenter, longitudinal, natura...

journal_title：Depression and anxiety

authors： Goisman RM,Allsworth J,Rogers MP,Warshaw MG,Goldenberg I,Vasile RG,Rodriguez-Villa F,Mallya G,Keller MB

更新日期：1998-01-01 00:00:00

abstract：:There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems in depression and anxiety disorders. The majority of evidence supports underactivation of serotonergic function and complex dysregulation of noradrenergic function, most consistent with overactivation o...

journal_title：Depression and anxiety

authors： Ressler KJ,Nemeroff CB

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Depression outcomes in research and clinical practice are commonly defined by the concepts of remission, recovery, relapse, and recurrence. Despite their widespread use, there has been little empirical examination of these concepts. Therefore, we investigated profiles of individual symptoms during each of th...

journal_title：Depression and anxiety

authors： Conradi HJ,Ormel J,de Jonge P

更新日期：2012-07-01 00:00:00

abstract：:Age at onset is an important dimension in the classification of mood disorders. Recent findings on early-onset (EO) versus late-onset (LO) unipolar chronic depressions support this subtyping. The aim of the present study was to determine clinical differences between EO and LO bipolar II chronic depression and to suppo...

journal_title：Depression and anxiety

authors： Benazzi F

更新日期：2001-01-01 00:00:00

abstract：:This review covers the literature since the publication of DSM-IV on the diagnostic criteria for panic attacks (PAs) and panic disorder (PD). Specific recommendations are made based on the evidence available. In particular, slight changes are proposed for the wording of the diagnostic criteria for PAs to ease the diff...

journal_title：Depression and anxiety

authors： Craske MG,Kircanski K,Epstein A,Wittchen HU,Pine DS,Lewis-Fernández R,Hinton D,DSM V Anxiety.,OC Spectrum.,Posttraumatic and Dissociative Disorder Work Group.

更新日期：2010-02-01 00:00:00

abstract：:Serotonergic (5-hydroxytryptamine; 5-HT) mechanisms have been implicated in a number of physiological and pathophysiological processes including mood, anxiety, and cognitive functioning. Among the many 5-HT receptor subtypes, the 5-HT2A receptors (5-HT2A-R) seem to be of particular importance in mediating these effect...

journal_title：Depression and anxiety

authors： Cohen H

更新日期：2005-01-01 00:00:00

abstract：:This study assessed striatal dopamine 1 (D1) receptor binding in patients with major depressive disorder and anger attacks (MDD+A) and healthy volunteers. We used positron emission tomography with [(11)C]SCH 23,390 to compare 10 patients with MDD+A to 10 healthy volunteers. [(11)C]SCH 23,390 binding in bilateral stria...

journal_title：Depression and anxiety

authors： Dougherty DD,Bonab AA,Ottowitz WE,Livni E,Alpert NM,Rauch SL,Fava M,Fischman AJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Although several studies have documented a higher prevalence of psychiatric disorders in children of depressed than nondepressed parents, previous research was conducted in predominantly White, middle, or upper-middle class populations. Only limited information is available on psychiatric disorders and psych...

journal_title：Depression and anxiety

authors： Feder A,Alonso A,Tang M,Liriano W,Warner V,Pilowsky D,Barranco E,Wang Y,Verdeli H,Wickramaratne P,Weissman MM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that posttraumatic stress disorder (PTSD) is associated with disrupted default mode network (DMN) connectivity, but findings across studies have not been uniform. Individual differences in relevant genes may account for some of the reported variability in the relationship betwe...

journal_title：Depression and anxiety

authors： Miller DR,Logue MW,Wolf EJ,Maniates H,Robinson ME,Hayes JP,Stone A,Schichman S,McGlinchey RE,Milberg WP,Miller MW

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Depression is a highly prevalent disease with a high morbidity and mortality risk. Its pathophysiology is not entirely clear. However, type 2 diabetes is an important risk factor for depression. One mechanism that may explain this association may include the formation of advanced glycation end products (AGEs...

journal_title：Depression and anxiety

authors： van Dooren FE,Pouwer F,Schalkwijk CG,Sep SJ,Stehouwer CD,Henry RM,Dagnelie PC,Schaper NC,van der Kallen CJ,Koster A,Denollet J,Verhey FR,Schram MT

更新日期：2017-01-01 00:00:00

abstract：:This study explores the psychometric properties of the Portuguese version of Corah's Dental Anxiety Scale (DAS), an instrument designed to assess the manifestations of dental anxiety. The DAS has been translated into several languages, but no adaptation and reliability analysis of the Portuguese version of the scale h...

journal_title：Depression and anxiety

authors： Hu LW,Gorenstein C,Fuentes D

更新日期：2007-01-01 00:00:00

abstract：:Clinical commentators widely interpret crying as a sign of depressed mood. However, there is virtually no empirical data on this topic, and the evidence that mood disorders alter crying is surprisingly weak. This study compared mood disordered patients to a nonpsychiatric reference group on the frequency, antecedents,...

journal_title：Depression and anxiety

authors： Rottenberg J,Cevaal A,Vingerhoets AJ

更新日期：2008-01-01 00:00:00

abstract：:Although the use of telemedicine in psychiatry has a long history in providing clinical care to patients, its use in clinical trials research has not yet been commonly employed. Telemedicine allows for the remote assessment of study patients, which could be done by a centralized, highly calibrated, and impartial cohor...

journal_title：Depression and anxiety

authors： Kobak KA,Williams JB,Jeglic E,Salvucci D,Sharp IR

更新日期：2008-01-01 00:00:00

abstract：:We successfully treated a 46-year-old narcoleptic woman suffering from atypical depression with bupropion hydrochloride. Diagnostic evaluation revealed a Beck Depression Inventory (BDI) score of 24, a short nocturnal REM-sleep latency, subjective and objective sleepiness (mean sleep latency (MSL) = 1.8 minutes), and t...

journal_title：Depression and anxiety

authors： Rye DB,Dihenia B,Bliwise DL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Patients with obsessive-compulsive disorder (OCD) experience abnormally high levels of uncertainty, and unpredictability is evaluated negatively and not well tolerated. The current study examined neural correlates of attentional processing in response to experimentally induced uncertainty in OCD. METHODS:Tw...

journal_title：Depression and anxiety

authors： Dieterich R,Endrass T,Kathmann N

更新日期：2017-11-01 00:00:00

abstract：:Given the high rates of maladjustment among children of depressed mothers, parenting is likely to cause significant life stress in this population, potentially worsening the course of mothers' depression. The present study is a comparison of severe life stress in 38 mothers and 62 non-mothers receiving treatment for r...

journal_title：Depression and anxiety

authors： Feske U,Shear MK,Anderson B,Cyranowski J,Strassburger M,Matty M,Luther J,Frank E

更新日期：2001-01-01 00:00:00

abstract：:A National Institutes of Health (National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Aging) working group meeting focused on the non-motor aspects of Parkinson's disease (PD). Below is the summary of the meeting presentations and recommendations for a res...

journal_title：Depression and anxiety

authors： Edwards E,Kitt C,Oliver E,Finkelstein J,Wagster M,McDonald WM

更新日期：2002-01-01 00:00:00

abstract：:Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...

journal_title：Depression and anxiety

authors： Chang SC

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Brain structures underlying posttraumatic stress disorder (PTSD) have been a focus of imaging studies, but associations between treatment outcome and alterations in brain structures remain largely unexamined. We longitudinally examined the relation of structural changes in the rostral anterior cingulate cort...

journal_title：Depression and anxiety

authors： Helpman L,Papini S,Chhetry BT,Shvil E,Rubin M,Sullivan GM,Markowitz JC,Mann JJ,Neria Y

更新日期：2016-05-01 00:00:00

abstract：:There is an urgent need for more rapidly effective pharmacotherapies for major depressive disorder and bipolar disorder (BP) that are efficacious and tolerable for depressed patients who respond poorly to conventional treatments. Multiple controlled trials have now demonstrated a rapid, nonsustained antidepressive res...

journal_title：Depression and anxiety

authors： Bobo WV,Vande Voort JL,Croarkin PE,Leung JG,Tye SJ,Frye MA

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Metacognitive therapy (MCT) is a relatively new approach to treating mental disorders. The aim of the current meta-analysis was to examine the efficacy of MCT in patients with mental disorders. METHOD:A comprehensive literature search revealed 16 published as well as unpublished studies on the efficacy of M...

journal_title：Depression and anxiety

authors： Normann N,van Emmerik AA,Morina N

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:A pooled analysis was performed on data from two studies evaluating the efficacy of once-daily extended-release quetiapine fumarate (quetiapine XR) monotherapy for patients with major depressive disorder. Through these analyses (based on Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale ...

journal_title：Depression and anxiety

authors： Thase ME,Demyttenaere K,Earley WR,Gustafsson U,Udd M,Eriksson H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Theory and research suggest that generalized anxiety disorder (GAD) is associated with diminished quality of life and restriction in valued action. The purpose of this study was to examine the relevance of values-consistent behavior (valued action) in understanding the impairment in quality of life in GAD. ...

journal_title：Depression and anxiety

authors： Michelson SE,Lee JK,Orsillo SM,Roemer L

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:We used a dot-probe paradigm to examine attention bias toward threat (i.e., angry) and happy face stimuli in severe mood dysregulation (SMD) versus healthy comparison (HC) youth. The tendency to allocate attention to threat is well established in anxiety and other disorders of negative affect. SMD is charact...

journal_title：Depression and anxiety

authors： Hommer RE,Meyer A,Stoddard J,Connolly ME,Mogg K,Bradley BP,Pine DS,Leibenluft E,Brotman MA

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:This study examined the feasibility and preliminary effectiveness of d-cycloserine (DCS)-augmented cognitive behavioral therapy (CBT) for children and adolescents with difficult-to-treat Obsessive Compulsive Disorder, in a double-blind randomized controlled pilot trial (RCT). METHODS:Seventeen children and ...

journal_title：Depression and anxiety

authors： Farrell LJ,Waters AM,Boschen MJ,Hattingh L,McConnell H,Milliner EL,Collings N,Zimmer-Gembeck M,Shelton D,Ollendick TH,Testa C,Storch EA

更新日期：2013-08-01 00:00:00