Abstract:
:Internet-delivered cognitive behavioral therapy (iCBT) was developed to overcome some of the barriers in accessing best practice face-to-face CBT. iCBT affords many benefits, such as high fidelity, greater accessibility, convenience, and reduced cost to patients and health-care systems. Recent meta-analyses of iCBT for depressive and anxiety disorders demonstrate large effect size for superiority of iCBT over control conditions (ES>.95; number needed to treat (NNT) = 2) and data collected in routine practice supports the effectiveness of these programs. Tailoring treatment to match patient variables may be one means to increase adherence and optimize clinical outcomes. However, we propose that a "personalized medicine" approach will require looking beyond patient characteristics and comorbidities to consideration of the cognitive processes that subserve depression and anxiety symptomatology.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Andrews G,Williams ADdoi
10.1002/da.22302subject
Has Abstractpub_date
2014-11-01 00:00:00pages
912-5issue
11eissn
1091-4269issn
1520-6394journal_volume
31pub_type
杂志文章abstract:BACKGROUND:Diagnostic criteria for DSM-5 posttraumatic stress disorder (PTSD) are in many ways similar to DSM-IV criteria, raising the possibility that it might be possible to closely approximate DSM-5 diagnoses using DSM-IV symptoms. If so, the resulting transformation rules could be used to pool research data based o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22364
更新日期:2015-07-01 00:00:00
abstract::Research has shown that obsessive compulsive disorder (OCD) is related to structural and functional abnormalities in the brain, and several authors have organized these findings into theories of OCD neuropsychiatric dysfunction. In this paper, these theories were used to develop a neural network model of OCD. OCD symp...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1998)8:3<91::aid-da1>3.0.c
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Preliminary evidence suggests intravenous ketamine has rapid effects on suicidal cognition, making it an attractive candidate for depressed patients at imminent risk of suicide. In the first randomized controlled trial of ketamine using an anesthetic control condition, we tested ketamine's acute effects on e...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22253
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Major depressive disorder (MDD) has been associated with changes in mean telomere length and mitochondrial DNA (mtDNA) copy number. This study investigates if clinical features of MDD differentially impact these molecular markers. METHODS:Data from a large, clinically ascertained sample of Han Chinese women...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22517
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To examine (1) clinically relevant anxiety with comorbid depression in an older population, and the presentation of subthreshold symptoms; (2) to assess anxiety and levels of comorbid depression associated with migration, religion, loneliness and long-term illness. METHODS:Analysis of Wave 1 of The Irish Lon...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22893
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:Comparing the overall and differential effects of psychodynamic psychotherapy (PDT) versus cognitive behavior therapy (CBT) for social anxiety disorder (SAD). DESIGN:Patients with a primary SAD (N = 47) were randomly assigned to PDT (N = 22) or CBT (N = 27). Both PDT and CBT consisted of up to 36 sessions (...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22246
更新日期:2014-05-01 00:00:00
abstract::There are well-established sex differences in the prevalence of certain mental disorders. Work in animal models has provided us with an emerging understanding of the role that epigenetic factors play in establishing sex differences in the brain during development. Similarly, work in animal models, and a more limited b...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.22167
更新日期:2013-12-01 00:00:00
abstract::This paper discusses the role of psychosocial intervention in the treatment of suicidal youth, summarizes the existing relevant literature, describes model programs for treating suicidal youth, and discusses efficacy-to-effectiveness issues in working with this population. ...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.1066
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20612
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.23105
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:There is ample evidence of the efficacy of cognitive-behavioral therapy (CBT) for depression in adolescents, including Puerto Rican adolescents. However, there is still a high percentage of adolescents who do not respond to a standard "dose" of 12 sessions of CBT. This clinical case study explores the charac...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20457
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Generalized anxiety disorder (GAD) is a common and sometimes disabling condition often associated with stressful life events that involve significant loss or danger. The disorder appears moderately heritable. Polymorphisms in the RGS2 (regulator of G-protein signaling 2) gene were recently associated with an...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20528
更新日期:2009-01-01 00:00:00
abstract::In this analysis we examined studies of tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) to compare efficacy and drop-out rates. Frequency of reported side effects was also studied. Using Medline, we located 36 clinical trials of TCAs and SSRIs in a double-blind comparison. We perfo...
journal_title:Depression and anxiety
pub_type: 杂志文章,meta分析
doi:10.1002/(sici)1520-6394(1997)6:1<10::aid-da2>3.0.c
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:We used a dot-probe paradigm to examine attention bias toward threat (i.e., angry) and happy face stimuli in severe mood dysregulation (SMD) versus healthy comparison (HC) youth. The tendency to allocate attention to threat is well established in anxiety and other disorders of negative affect. SMD is charact...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22145
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:The link between systemic inflammation and depression has been deeply investigated, but relatively few studies explored symptom-specific associations, mostly focusing on common inflammatory biomarkers like C-reactive protein (CRP) levels. METHODS:We investigated associations of low-grade inflammation with d...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23070
更新日期:2020-09-01 00:00:00
abstract::This review examines the question of whether there should be a cluster of disorders, including the adjustment disorders (ADs), acute stress disorder (ASD), posttraumatic stress disorder (PTSD), and the dissociative disorders (DDs), in a section devoted to abnormal responses to stress and trauma in the DSM-5. Environme...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.20845
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Although numerous studies have examined the role of latent predispositions to internalizing and externalizing disorders in the structure of comorbidity among common mental disorders, none examined latent predispositions in predicting development of comorbidity. METHODS:A novel method was used to study the r...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20760
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:This study examined the feasibility and preliminary effectiveness of d-cycloserine (DCS)-augmented cognitive behavioral therapy (CBT) for children and adolescents with difficult-to-treat Obsessive Compulsive Disorder, in a double-blind randomized controlled pilot trial (RCT). METHODS:Seventeen children and ...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22132
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Theory and research suggest that generalized anxiety disorder (GAD) is associated with diminished quality of life and restriction in valued action. The purpose of this study was to examine the relevance of values-consistent behavior (valued action) in understanding the impairment in quality of life in GAD. ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20793
更新日期:2011-05-01 00:00:00
abstract::Data from early studies of selective serotonin reuptake inhibitors have shown that these agents are effective in the treatment of social anxiety disorder (social phobia). This review highlights the outcomes of three large clinical trials of paroxetine in patients with social anxiety disorder. In two of the studies, pa...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Pediatric psychopharmacology is hindered by the relative lack of controlled, empirical clinical trials [Shatzberg and Nemeroff, 1998: Washington, D.C.: The American Psychiatric Press, Inc. p 301-306]. Psychiatric disorders in children and adolescents carry considerable morbidity, impede development, and carry a signif...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/1520-6394(2000)12:1+<85::AID-DA12>3.0.CO;2
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Whether psychological resilience correlates with neurocognitive performance is largely unknown. Therefore, we assessed association between neurocognitive performance and resilience in individuals with a history of childhood abuse or trauma exposure. METHODS:In this cross-sectional study of 226 highly trauma...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20675
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Parental mental disorders have been shown to predict offspring's mental health problems. We examined whether pathways from parental mental disorders to offspring's psychiatric work disability in early adulthood are mediated through offspring's mental disorders and social disadvantage in adolescence. METHODS...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22847
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Smoking in patients with bipolar disorder is known to be related to suicidality. This link has not been investigated, however, in community-based samples. The aim of this study is to delineate the sociodemographic and clinical characteristics of bipolar smokers and examine the relationship between these char...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22107
更新日期:2013-10-01 00:00:00
abstract::Functional impairment might amplify suicide risk in later life. A positive view of the future may reduce this risk. We tested the hypothesis that hopelessness and positive future orientation moderate the association between functional status and suicide ideation in a sample of 136 patients, 55 years of age or older, i...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20224
更新日期:2007-01-01 00:00:00
abstract::The growing recognition and occurrence of traumatic exposure in the general population has given increased salience to the need to understand the concept of resilience. More than just the "flip side" of a risk factor, the notion of resilience encompasses psychological and biological characteristics, intrinsic to an in...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.20175
更新日期:2007-01-01 00:00:00
abstract::There is an urgent need for more rapidly effective pharmacotherapies for major depressive disorder and bipolar disorder (BP) that are efficacious and tolerable for depressed patients who respond poorly to conventional treatments. Multiple controlled trials have now demonstrated a rapid, nonsustained antidepressive res...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.22505
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explor...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22672
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:To examine the potential mediating role of parenting behaviors in the longitudinal, bidirectional relationships between maternal depression and child internalizing symptoms (i.e. depression and anxiety). METHODS:We analyzed data from 4,581 mother-child dyads from the Fragile Families and Child Wellbeing Stu...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22688
更新日期:2018-01-01 00:00:00
abstract::This report describes the reactivation of a posttraumatic stress disorder (PTSD) after a minor head injury in two young women who had recovered from extreme stress caused by sexual abuse during adolescence. Intrusive thoughts, images, dreams, and phobic avoidance bear a direct relationship to the specific circumstance...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1998)8:1<43::aid-da9>3.0.c
更新日期:1998-01-01 00:00:00