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  • Role of antenatal plasma cytomegalovirus DNA levels on pregnancy outcome and HIV-1 vertical transmission among mothers in the University of Zimbabwe birth cohort study (UZBCS).

    abstract:INTRODUCTION:Despite being a leading infectious cause of childhood disability globally, testing for cytomegalovirus (CMV) infections in pregnancy is generally not done in Sub-Sahara Africa (SSA), where breastfeeding practice is almost universal. Whilst CMV and human immunodeficiency virus (HIV) are both endemic in SSA,...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Duri K,Chimhuya S,Gomo E,Munjoma PT,Chandiwana P,Yindom LM,Mhandire K,Ziruma A,Mtapuri-Zinyowera S,Mazengera LR,Misselwitz B,Gumbo FZ,Jordi S,Rowland-Jones S,for (UZBCS) The U Z Birth Cohort Study Team.

    更新日期:2021-01-29 00:00:00

  • Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers.

    abstract:BACKGROUND:Diverse vaccination outcomes and protection levels among different populations pose a serious challenge to the development of an effective malaria vaccine. Co-infections are among many factors associated with immune dysfunction and sub-optimal vaccination outcomes. Chronic, asymptomatic viral infections can ...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Tumbo AM,Schindler T,Dangy JP,Orlova-Fink N,Bieri JR,Mpina M,Milando FA,Juma O,Hamad A,Nyakarungu E,Chemba M,Mtoro A,Ramadhan K,Olotu A,Makweba D,Mgaya S,Stuart K,Perreau M,Stapleton JT,Jongo S,Hoffman SL,Tanner

    更新日期:2021-01-26 00:00:00

  • Cross-sectional retrospective analysis of clinical characteristics of chronic hepatitis B patients with oral antiviral treatment in eastern China.

    abstract:BACKGROUND:In China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population. METHODS:The data were retrospectively extracted from the hospital medical charts of five centers...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Gu J,Yu G,Zhang X,Zhang S,Cai H,Ye C,Yang Y,Li D,Tong Z,Shen H,Chen H,Ding F,Lai X,Liu J,Xu M,Wu W

    更新日期:2021-01-13 00:00:00

  • Study on suitable analysis method for HIV-1 non-catalytic integrase inhibitor.

    abstract:BACKGROUND:Integrase (IN) is an essential protein for HIV replication that catalyzes insertion of the reverse-transcribed viral genome into the host chromosome during the early steps of viral infection. Highly active anti-retroviral therapy is a HIV/AIDS treatment method that combines three or more antiviral drugs ofte...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Park KH,Kim M,Bae SE,Lee HJ,Kim KC,Choi BS,Kim YB

    更新日期:2021-01-13 00:00:00

  • Seewis hantavirus in common shrew (Sorex araneus) in Sweden.

    abstract:BACKGROUND:Rodent borne hantaviruses are emerging viruses infecting humans through inhalation. They cause hemorrhagic fever with renal syndrome and hemorrhagic cardiopulmonary syndrome. Recently, hantaviruses have been detected in other small mammals such as Soricomorpha (shrews, moles) and Chiroptera (bats), suggested...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Lwande OW,Mohamed N,Bucht G,Ahlm C,Olsson G,Evander M

    更新日期:2020-12-29 00:00:00

  • Seroprevalence and genotypic characterization of HBV among low risk voluntary blood donors in Nairobi, Kenya.

    abstract:BACKGROUND:Hepatitis B virus (HBV) causes significant morbidity and mortality globally primarily due to its ability to cause hepatitis, liver cirrhosis and hepatocellular carcinoma. The Kenya National Blood Transfusion Services screens for Hepatitis B antibodies using the chemiluminescent microparticle immunoassay meth...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Aluora PO,Muturi MW,Gachara G

    更新日期:2020-11-13 00:00:00

  • Author Correction: In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2.

    abstract::The original version of the acknowledgement unfortunately contained a mistake. ...

    journal_title:Virology journal

    pub_type: 已发布勘误


    authors: Signer J,Jonsdottir HR,Albrich WC,Strasser M,Züst R,Ryter S,Ackermann-Gäumann R,Lenz N,Siegrist D,Suter A,Schoop R,Engler OB

    更新日期:2020-11-09 00:00:00

  • Genomic and phylogenetic characterization of ChPV2, a novel goat PV closely related to the Xi-PV1 species infecting bovines.

    abstract:BACKGROUND:Papillomaviruses (PVs) infecting artiodactyls are very diverse, and only second in number to PVs infecting primates. PVs associated to lesions in economically important ruminant species have been isolated from cattle and sheep. METHODS:Potential PV DNA from teat lesions of a Damascus goat was isolated, clon...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Willemsen A,van den Boom A,Dietz J,Bilge Dagalp S,Dogan F,Bravo IG,Ehrhardt A,Ehrke-Schulz E

    更新日期:2020-10-30 00:00:00

  • Rapid point-of-care detection of SARS-CoV-2 using reverse transcription loop-mediated isothermal amplification (RT-LAMP).

    abstract:BACKGROUND:Fast, reliable and easy to handle methods are required to facilitate urgently needed point-of-care testing (POCT) in the current coronavirus pandemic. Life-threatening severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread all over the world, infecting more than 33,500,000 people and...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Mautner L,Baillie CK,Herold HM,Volkwein W,Guertler P,Eberle U,Ackermann N,Sing A,Pavlovic M,Goerlich O,Busch U,Wassill L,Huber I,Baiker A

    更新日期:2020-10-21 00:00:00

  • COVID-19 pandemic: current knowledge about the role of pets and other animals in disease transmission.

    abstract::On 11 March 2020, the World Health Organization (WHO) announced Corona Virus Disease (COVID-19), a disease caused by a pathogen called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pandemic. This ongoing pandemic has now been reported in 215 countries with more than 23 million confirmed cases and mor...

    journal_title:Virology journal

    pub_type: 杂志文章,评审


    authors: Kiros M,Andualem H,Kiros T,Hailemichael W,Getu S,Geteneh A,Alemu D,Abegaz WE

    更新日期:2020-10-02 00:00:00

  • Favipiravir versus other antiviral or standard of care for COVID-19 treatment: a rapid systematic review and meta-analysis.

    abstract:BACKGROUND:The COVID-19 causing coronavirus is an enveloped RNA virus that utilizes an enzyme RNA dependent RNA polymerase for its replication. Favipiravir (FVP) triphosphate, a purine nucleoside analog, inhibits that enzyme. We have conducted this systematic review and meta-analysis on efficacy and safety of the drug ...

    journal_title:Virology journal

    pub_type: 杂志文章,meta分析


    authors: Shrestha DB,Budhathoki P,Khadka S,Shah PB,Pokharel N,Rashmi P

    更新日期:2020-09-24 00:00:00

  • Prevalence of human papillomavirus genotypes and precancerous cervical lesions in a screening population in Beijing, China: analysis of results from China's top 3 hospital, 2009-2019.

    abstract:BACKGROUND:Cervical cancer is the fourth most common cancer in women. Early detection and diagnosis play an important role in secondary prevention of cervical cancer. This study aims to provide more information to develop an effective strategy for the prevention and control of cervical cancer in northern China. METHOD...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Liu Y,Ang Q,Wu H,Xu J,Chen D,Zhao H,Liu H,Guo X,Gu Y,Qiu H

    更新日期:2020-07-13 00:00:00

  • Genotyping of 30 kinds of cutaneous human papillomaviruses by a multiplex microfluidic loop-mediated isothermal amplification and visual detection method.

    abstract:BACKGROUND:Human papillomaviruses (HPVs), a group of non-enveloped small viruses with double-stranded circular DNA which lead to multiple skin diseases such as benign warts, are commonly seen in clinics. The current HPV detection systems aim mainly at mucosal HPVs, however, an efficient clinical approach for cutaneous ...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Wang Y,Ge G,Mao R,Wang Z,Sun YZ,Du YG,Gao XH,Qi RQ,Chen HD

    更新日期:2020-07-09 00:00:00

  • Characterization of neuraminidase inhibitor-resistant influenza virus isolates from immunocompromised patients in the Republic of Korea.

    abstract:BACKGROUND:The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Viruses Surveillance System (KINRESS) to monitor epidemics of influenza and Severe Acute Respiratory Infe...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Kim HM,Lee N,Kim MS,Kang C,Chung YS

    更新日期:2020-07-06 00:00:00

  • Association of LIN28B polymorphisms with chronic hepatitis B virus infection.

    abstract:BACKGROUND:LIN28B is involved in multiple cellular developmental processes, tissue inflammatory response and tumourigenesis. The association of LIN28B polymorphisms with hepatitis B virus (HBV) infection remains unknown. METHODS:This study investigated the association of LIN28B rs314277, rs314280, rs369065 and rs77599...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Han Q,Sang J,Fan X,Wang X,Zeng L,Zhang X,Zhang K,Li N,Lv Y,Liu Z

    更新日期:2020-06-22 00:00:00

  • Oncolytic Newcastle disease virus delivered by Mesenchymal stem cells-engineered system enhances the therapeutic effects altering tumor microenvironment.

    abstract:BACKGROUND:Human papillomavirus (HPV)-associated malignancy remain a main cause of cancer in men and women. Cancer immunotherapy has represented great potential as a new promising cancer therapeutic approach. Here, we report Mesenchymal stem cells (MSCs) as a carrier for the delivery of oncolytic Newcastle disease viru...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Keshavarz M,Ebrahimzadeh MS,Miri SM,Dianat-Moghadam H,Ghorbanhosseini SS,Mohebbi SR,Keyvani H,Ghaemi A

    更新日期:2020-05-05 00:00:00

  • Co-circulation of multiple reassortant H6 subtype avian influenza viruses in wild birds in eastern China, 2016-2017.

    abstract:BACKGROUND:H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China, a crucial stopover or wintering site for migratory wild birds along the East As...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Hu C,Li X,Zhu C,Zhou F,Tang W,Wu D,Li Z,Zhou L,Liu J,Wei X,Cui J,Wang T,He G

    更新日期:2020-04-29 00:00:00

  • Identification of novel human adenovirus candidates using the coxsackievirus and adenovirus receptor for cell entry.

    abstract:BACKGROUND:There are over 100 known human adenovirus (HAdV) types, which are able to cause a broad variety of different self-limiting but also lethal diseases especially in immunocompromised patients. Only limited information about the pathogenesis and biology of the majority of these virus types is available. In the p...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Mese K,Bunz O,Schellhorn S,Volkwein W,Jung D,Gao J,Zhang W,Baiker A,Ehrhardt A

    更新日期:2020-04-09 00:00:00

  • Investigation of the immunogenicity of Zika glycan loop.

    abstract:BACKGROUND:Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus. Previous studies have identified neutralizing antibodies from Zika patients that bind to quaternary epitopes across neighboring envelope (E) proteins, called E dimer epitopes (EDE). An asparagine-linked glycan on the "glycan loop...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Henderson EA,Tam CC,Cheng LW,Ngono AE,Nguyen AV,Shresta S,McGee M,Padgett H,Grill LK,Martchenko Shilman M

    更新日期:2020-03-31 00:00:00

  • Suitability of individual and bulk milk samples to investigate the humoral immune response to lumpy skin disease vaccination by ELISA.

    abstract:BACKGROUND:The detection of antibodies against capripoxvirus has become easier with a commercially available ELISA validated for serum and plasma. In order to explore its suitability for immunological investigations on alternative samples, this study targeted milk as sample matrix available through non-invasive samplin...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Milovanović M,Milićević V,Radojičić S,Valčić M,Hoffmann B,Dietze K

    更新日期:2020-03-05 00:00:00

  • Inhibition effects of patchouli alcohol against influenza a virus through targeting cellular PI3K/Akt and ERK/MAPK signaling pathways.

    abstract:BACKGROUND:Patchouli alcohol (PA) is a tricyclic sesquiterpene extracted from Pogostemonis Herba, which is a traditional Chinese medicine used for therapy of inflammatory diseases. Recent studies have shown that PA has various pharmacological activities, including anti-bacterial and anti-viral effects. METHODS:In this...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Yu Y,Zhang Y,Wang S,Liu W,Hao C,Wang W

    更新日期:2019-12-23 00:00:00

  • Mapping of CD4+ T-cell epitopes in bovine leukemia virus from five cattle with differential susceptibilities to bovine leukemia virus disease progression.

    abstract:BACKGROUND:Bovine leukemia virus (BLV), which is closely related to human T-cell leukemia virus, is the etiological agent of enzootic bovine leukosis, a disease characterized by a highly prolonged course involving persistent lymphocytosis and B-cell lymphoma. The bovine major histocompatibility complex class II region ...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Bai L,Takeshima SN,Sato M,Davis WC,Wada S,Kohara J,Aida Y

    更新日期:2019-12-16 00:00:00

  • A novel avian isolate of hepatitis E virus from Pakistan.

    abstract:BACKGROUND:Avian hepatitis E virus (aHEV) has been associated with hepatitis-splenomegaly syndrome (HSS) in chickens along with asymptomatic subclinical infection in many cases. So far, four genotypes have been described, which cause infection in chickens, specifically in broiler breeders and layer chickens. In the pre...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Iqbal T,Rashid U,Idrees M,Afroz A,Kamili S,Purdy MA

    更新日期:2019-11-21 00:00:00

  • Codon usage patterns of LT-Ag genes in polyomaviruses from different host species.

    abstract:BACKGROUND:Polyomaviruses (PyVs) have a wide range of hosts, from humans to fish, and their effects on hosts vary. The differences in the infection characteristics of PyV with respect to the host are assumed to be influenced by the biochemical function of the LT-Ag protein, which is related to the cytopathic effect and...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Cho M,Kim H,Son HS

    更新日期:2019-11-14 00:00:00

  • Whole-genome sequencing of human Pegivirus variant from an Egyptian patient co-infected with hepatitis C virus: a case report.

    abstract:BACKGROUND:Human pegivirus (HPgV) is structurally similar to hepatitis C virus (HCV) and was discovered 20 years ago. Its distribution, natural history and exact rule of this viral group in human hosts remain unclear. Our aim was to determine, by deep next-generation sequencing (NGS), the entire genome sequence of HPgV...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Soliman HK,Abouelhoda M,El Rouby MN,Ahmed OS,Esmat G,Hassan ZK,Hafez MM,Mehaney DA,Selvaraju M,Darwish RK,Osman YA,Zekri AN

    更新日期:2019-11-11 00:00:00

  • Tumor necrosis factor-α-induced protein 8-like 2 mRNA in peripheral blood mononuclear cells is associated with the disease progression of chronic hepatitis B virus infection.

    abstract:BACKGROUND:Tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) is a novel target and molecule in the negative regulation of immune homeostasis. The present study aimed to investigate the dynamic expression of TIPE2 mRNA during the progression of chronic hepatitis B virus (HBV) infection. METHODS:A total of 19...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Liu Y,Jin J,Ji J,Gao XM,Fan YC

    更新日期:2019-10-28 00:00:00

  • Serum and tissue miRNAs: potential biomarkers for the diagnosis of cervical cancer.

    abstract:BACKGROUND:Finding new biomarkers for the early detection of cervical cancer is an essential requirement in this field. In this study, we aimed to evaluate the expression level of potential biomarkers in progression of cervical cancer in patients with cervical cancer compared to normal subjects. METHODS:The expression...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Farzanehpour M,Mozhgani SH,Jalilvand S,Faghihloo E,Akhavan S,Salimi V,Azad TM

    更新日期:2019-10-07 00:00:00

  • The altered gut virome community in rhesus monkeys is correlated with the gut bacterial microbiome and associated metabolites.

    abstract:BACKGROUND:The gut microbiome is closely associated with the health of the host; although the interaction between the bacterial microbiome and the whole virome has rarely been studied, it is likely of medical importance. Examination of the interactions between the gut bacterial microbiome and virome of rhesus monkey wo...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Li H,Li H,Wang J,Guo L,Fan H,Zheng H,Yang Z,Huang X,Chu M,Yang F,He Z,Li N,Yang J,Wu Q,Shi H,Liu L

    更新日期:2019-08-19 00:00:00

  • Human immunodeficiency virus type 1 ((HIV-1) subtypes in the northwest region, Cameroon.

    abstract:BACKGROUND:The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence in Cameroon, all the major HIV subtypes alongside several circulating recombinant forms (CRFs) and uniqu...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Abongwa LE,Nyamache AK,Torimiro JN,Okemo P,Charles F

    更新日期:2019-08-15 00:00:00

  • Antiviral activity of Piscidin 1 against pseudorabies virus both in vitro and in vivo.

    abstract:BACKGROUND:Swine-origin virus infection spreading widely could cause significant economic loss to porcine industry. Novel antiviral agents need to be developed to control this situation. METHODS:In this study, we evaluated the activities of five broad-spectrum antimicrobial peptides (AMPs) against several important sw...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Hu H,Guo N,Chen S,Guo X,Liu X,Ye S,Chai Q,Wang Y,Liu B,He Q

    更新日期:2019-07-31 00:00:00

  • A divergent strain of melon chlorotic spot virus isolated from black medic (Medicago lupulina) in Austria.

    abstract::A tenuivirus, referred to here as JKI 29327, was isolated from a black medic (Medicago lupulina) plant collected in Austria. The virus was mechanically transmitted to Nicotiana benthamiana, M. lupulina, M. sativa, Pisum sativum and Vicia faba. The complete genome was determined by high throughput sequencing. The genom...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Gaafar YZA,Richert-Pöggeler KR,Sieg-Müller A,Lüddecke P,Herz K,Hartrick J,Seide Y,Vetten HJ,Ziebell H

    更新日期:2019-07-05 00:00:00

  • Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China.

    abstract:BACKGROUND:Human papillomavirus (HPV) E6 and E7 oncoproteins play a crucial role in HPV-related diseases, such as cervical cancer, and can be used as ideal targets for therapeutic vaccines. Human leukocyte antigen (HLA) participates in the immune response to block HPV infection and invasion by its target/recognition fu...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: He J,Yang Y,Chen Z,Liu Y,Bao S,Zhao Y,Ding X

    更新日期:2019-05-28 00:00:00

  • Comparative genomic analyses of a virulent pseudorabies virus and a series of its in vitro passaged strains.

    abstract:BACKGROUND:Pseudorabies virus (PRV) of the family Herpesviridae is the causative agent of Aujeszky's disease. Attenuation of PRV by serial passaging in vitro is a well-established method; however, the dynamic variations occurring on viral genome during this process have not been characterized. METHODS:Genome sequencin...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Ye C,Wu J,Tong W,Shan T,Cheng X,Xu J,Liang C,Zheng H,Li G,Tong G

    更新日期:2018-12-29 00:00:00

  • Monitoring HIV DNA and cellular activation markers in HIV-infected humanized mice under cART.

    abstract:BACKGROUND:The major obstacle to cure of HIV type-1 infection is the presence of the HIV reservoir, hidden from the immune system and insensitive to combined antiretroviral therapy (cART). Eradication approaches have been hindered by the difficulty for accurately monitoring its size in vivo, especially in the lymphoid ...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Rochat MA,Schlaepfer E,Kuster SP,Li D,Audige A,Ivic S,Fahrny A,Speck RF

    更新日期:2018-12-17 00:00:00

  • The so far farthest reaches of the double jelly roll capsid protein fold.

    abstract:BACKGROUND:During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until recently, only a few prokaryotic viruses had been described for one of the lin...

    journal_title:Virology journal

    pub_type: 杂志文章,评审


    authors: San Martín C,van Raaij MJ

    更新日期:2018-11-23 00:00:00

  • Herpes simplex virus type 2 infection triggers AP-1 transcription activity through TLR4 signaling in genital epithelial cells.

    abstract:BACKGROUND:The pattern recognition receptors (PPRs) are the earliest phase of the host defense against pathogens in genital epithelium, and toll-like receptors (TLRs) are best characterized PPRs mediating innate immune responses. Herpes simplex virus type 2 (HSV-2), a member of herpesviridae family, causes one of the m...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Lv X,Wang H,Su A,Xu S,Chu Y

    更新日期:2018-11-12 00:00:00

  • Reduction of the survival time of pig xenotransplants by porcine cytomegalovirus.

    abstract:BACKGROUND:Xenotransplantation using pig cells, tissues and organs may help to overcome the shortage of human tissues and organs for the treatment of tissue and organ failure. Progress in the prevention of immunological rejection using genetically modified pigs and new, more effective, immunosuppression regimens will a...

    journal_title:Virology journal

    pub_type: 杂志文章,评审


    authors: Denner J

    更新日期:2018-11-08 00:00:00

  • A multiplex one-tube nested real time RT-PCR assay for simultaneous detection of respiratory syncytial virus, human rhinovirus and human metapneumovirus.

    abstract:BACKGROUND:Respiratory syncytial virus (RSV), human Rhinovirus (HRV) and human Metapneumo Virus (HMPV) are important viral pathogens causing acute respiratory tract infections in the hospitalized patients. Sensitive and accurate detection of RSV, HRV and HMPV is necessary for clinical diagnosis and treatment. RESULTS:...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Feng ZS,Zhao L,Wang J,Qiu FZ,Zhao MC,Wang L,Duan SX,Zhang RQ,Chen C,Qi JJ,Fan T,Li GX,Ma XJ

    更新日期:2018-10-30 00:00:00

  • Lymphatic endothelial cells promote productive and latent HIV infection in resting CD4+ T cells.

    abstract:BACKGROUND:An HIV cure has not yet been achieved because latent viral reservoirs persist, particularly in resting CD4+ T lymphocytes. In vitro, it is difficult to infect resting CD4+ T cells with HIV-1, but infections readily occur in vivo. Endothelial cells (EC) line the lymphatic vessels in the lymphoid tissues and r...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Schilthuis M,Verkaik S,Walhof M,Philipose A,Harlow O,Kamp D,Kim BR,Shen A

    更新日期:2018-10-03 00:00:00

  • Satisfactory virological response and fibrosis improvement of sofosbuvir-based regimens for Chinese patients with hepatitis C virus genotype 3 infection: results of a real-world cohort study.

    abstract:BACKGROUND:Chronic hepatitis C virus (HCV) genotype (GT) 3 infection with advanced liver disease has emerged as a challenging to treat by direct-acting antivirals (DAAs), but the efficacy of DAAs in Chinese HCV-GT3 patients is rarely reported. This study aimed to analyze the efficacy of sofosbuvir (SOF)-based regimens ...

    journal_title:Virology journal

    pub_type: 杂志文章


    authors: Tao YC,Deng R,Wang ML,Lv DD,Yuan M,Wang YH,Chen EQ,Tang H

    更新日期:2018-10-01 00:00:00

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