Genomic and phylogenetic characterization of ChPV2, a novel goat PV closely related to the Xi-PV1 species infecting bovines.

abstract：BACKGROUND:Human papillomavirus (HPV) bivalent and quadrivalent vaccines have been widely implemented in worldwide organized immunization programs. A nonavalent HPV vaccine is now available in several countries. The objective was to describe the fraction of squamous non-invasive high-grade cervical intraepithelial lesi...

journal_title：Virology journal

authors： Perez S,Iñarrea A,Pérez-Tanoira R,Gil M,López-Díez E,Valenzuela O,Porto M,Alberte-Lista L,Peteiro-Cancelo MA,Treinta A,Carballo R,Reboredo MC,Alvarez-Argüelles ME,Purriños MJ

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:ORFV attenuated live vaccines have been the main prophylactic measure against contagious ecthyma in sheep and goats in the last decades, which play an important role in preventing the outbreak of the disease. However, the available vaccines do not induce lasting immunity in sheep and goats. On the other hand...

journal_title：Virology journal

authors： Zhao K,He W,Gao W,Lu H,Han T,Li J,Zhang X,Zhang B,Wang G,Su G,Zhao Z,Song D,Gao F

更新日期：2011-12-29 00:00:00

abstract：BACKGROUND:Influenza virus infections are responsible for significant morbidity worldwide and therefore it remains a high priority to develop more broadly protective vaccines. Adjuvation of current seasonal influenza vaccines has the potential to achieve this goal. METHODS:To assess the immune potentiating properties ...

journal_title：Virology journal

authors： Cox F,Saeland E,Baart M,Koldijk M,Tolboom J,Dekking L,Koudstaal W,Lövgren Bengtsson K,Goudsmit J,Radošević K

更新日期：2015-12-08 00:00:00

abstract：:The prevalence of North American orthopoxviruses in nature is unknown and may be more difficult to ascertain due to wide spread use of vaccinia virus recombinant vaccines in the wild. A real time PCR assay was developed to allow for highly sensitive and specific detection of North American orthopoxvirus DNA in animal ...

journal_title：Virology journal

authors： Gallardo-Romero NF,Velasco-Villa A,Weiss SL,Emerson GL,Carroll DS,Hughes CM,Li Y,Karem KL,Damon IK,Olson VA

更新日期：2011-06-20 00:00:00

abstract：BACKGROUND:Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationship of HLA-DP rs9277535 and HLA-DQ rs7453920 with the outcomes of HCV infection. METHODS:The rs927...

journal_title：Virology journal

authors： Huang P,Fan H,Tian T,Liao P,Li J,Yu R,Xia X,Feng Y,Wang J,Liu Y,Zhang Y,Yue M

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:Since avian-origin H3N2 canine influenza virus (CIV) was first identified in South Korea in 2008, the novel influenza virus has been reported in several countries in Asia. Reverse zoonotic transmission of pandemic H1N1 (2009) influenza virus (pH1N1) has been observed in a broad range of animal species. Viral...

journal_title：Virology journal

authors： Na W,Lyoo KS,Song EJ,Hong M,Yeom M,Moon H,Kang BK,Kim DJ,Kim JK,Song D

更新日期：2015-09-04 00:00:00

abstract：BACKGROUND:There are over 100 known human adenovirus (HAdV) types, which are able to cause a broad variety of different self-limiting but also lethal diseases especially in immunocompromised patients. Only limited information about the pathogenesis and biology of the majority of these virus types is available. In the p...

journal_title：Virology journal

authors： Mese K,Bunz O,Schellhorn S,Volkwein W,Jung D,Gao J,Zhang W,Baiker A,Ehrhardt A

更新日期：2020-04-09 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne virus that has four serotypes. Collection of serum from patients is time- and labor- consuming, and presents a high injury risk for infants and children. The genomic and serological diagnosis of imported dengue fever from a urine sample was used as a non-invasive diagnostic meth...

journal_title：Virology journal

authors： Ma X,Zhen W,Yang P,Sun X,Nie W,Zhang L,Xu H,Hu K

更新日期：2014-03-25 00:00:00

abstract：BACKGROUND:Rodent borne hantaviruses are emerging viruses infecting humans through inhalation. They cause hemorrhagic fever with renal syndrome and hemorrhagic cardiopulmonary syndrome. Recently, hantaviruses have been detected in other small mammals such as Soricomorpha (shrews, moles) and Chiroptera (bats), suggested...

journal_title：Virology journal

authors： Lwande OW,Mohamed N,Bucht G,Ahlm C,Olsson G,Evander M

更新日期：2020-12-29 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a blood borne infectious disease that affects the liver. Human bone marrow mesenchymal stem cells (BMSCs) may serve as a cell source for adult stem cell transplantation in liver repair. However, the susceptibility of human BMSCs to HBV infection is poorly understood. The ...

journal_title：Virology journal

authors： Ma R,Xing Q,Shao L,Wang D,Hao Q,Li X,Sai L,Ma L

更新日期：2011-10-31 00:00:00

abstract：BACKGROUND:The genus Orbivirus includes several species that infect livestock - including Bluetongue virus (BTV) and African horse sickness virus (AHSV). These viruses have linear dsRNA genomes divided into ten segments, all of which have previously been assumed to be monocistronic. RESULTS:Bioinformatic evidence is p...

journal_title：Virology journal

authors： Firth AE

更新日期：2008-04-14 00:00:00

abstract：:More than 20 years ago, hantaviral antigens were reported in tissues of the Eurasian common shrew (Sorex araneus), Eurasian water shrew (Neomys fodiens) and common mole (Talpa europea), suggesting that insectivores, or soricomorphs, might serve as reservoirs of unique hantaviruses. Using RT-PCR, sequences of a genetic...

journal_title：Virology journal

authors： Song JW,Gu SH,Bennett SN,Arai S,Puorger M,Hilbe M,Yanagihara R

更新日期：2007-10-30 00:00:00

abstract：BACKGROUND:An HIV cure has not yet been achieved because latent viral reservoirs persist, particularly in resting CD4+ T lymphocytes. In vitro, it is difficult to infect resting CD4+ T cells with HIV-1, but infections readily occur in vivo. Endothelial cells (EC) line the lymphatic vessels in the lymphoid tissues and r...

journal_title：Virology journal

authors： Schilthuis M,Verkaik S,Walhof M,Philipose A,Harlow O,Kamp D,Kim BR,Shen A

更新日期：2018-10-03 00:00:00

abstract：:Herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases worldwide. The first time infection of the mother may lead to severe illness in pregnancy and may be associated with virus transmission from mother to foetus/newborn. Since the incidence of this sexually transmitted infe...

journal_title：Virology journal

authors： Anzivino E,Fioriti D,Mischitelli M,Bellizzi A,Barucca V,Chiarini F,Pietropaolo V

更新日期：2009-04-06 00:00:00

abstract：BACKGROUND:SEN virus is a blood-borne, circular ssDNA virus and possessing nine genotypes (A to I). Among nine genotypes, SENV-D and SENV-H genotypes have the strong link with patients with unknown (none-A to E) hepatitis infections. Infection with blood-borne viruses is the second important cause of death in thalassem...

journal_title：Virology journal

authors： Karimi-Rastehkenari A,Bouzari M

更新日期：2010-01-02 00:00:00

abstract：BACKGROUND:Foot-and-mouth disease (FMD) is an extremely contagious viral disease of cattle, pigs, sheep, goats, and many cloven-hoofed wild animals. FMDV serotypes O and Asia 1 have circulated separately in China during the last fifty years, and eliminating infected animals and vaccination are the main policies to prev...

journal_title：Virology journal

authors： Wu L,Jiang T,Lu ZJ,Yang YM,Sun P,Liang Z,Li D,Fu YF,Cao YM,Liu XT,Liu ZX

更新日期：2011-04-23 00:00:00

abstract：BACKGROUND:Uukuniemi virus (UUKV) belongs to the Phlebovirus genus in the family Bunyaviridae. As a non-pathogenic virus for humans UUKV has served as a safe model bunyavirus in a number of studies addressing fundamental questions such as organization and regulation of viral genes, genome replication, structure and ass...

journal_title：Virology journal

authors： Katz A,Freiberg AN,Backström V,Schulz AR,Mateos A,Holm L,Pettersson RF,Vaheri A,Flick R,Plyusnin A

更新日期：2010-08-10 00:00:00

abstract：BACKGROUND:Highly pathogenic avian influenza virus (AIV) subtype H5N1 remains a threat to poultry. Duck enteritis virus (DEV)-vectored vaccines expressing AIV H5N1 hemagglutinin (HA) may be viable AIV and DEV vaccine candidates. METHODS:To facilitate the generation and further improvement of DEV-vectored HA(H5) vaccin...

journal_title：Virology journal

authors： Wang J,Ge A,Xu M,Wang Z,Qiao Y,Gu Y,Liu C,Liu Y,Hou J

更新日期：2015-08-13 00:00:00

abstract：BACKGROUND:Crimean-Congo Hemorrhagic Fever virus (CCHFV), a member of the genus Nairovirus, family Bunyaviridae, is a tick-borne pathogen causing severe disease in humans. To better understand the CCHFV life cycle and explore potential intervention strategies, we studied the biosynthesis and intracellular targeting of ...

journal_title：Virology journal

authors： Haferkamp S,Fernando L,Schwarz TF,Feldmann H,Flick R

更新日期：2005-04-25 00:00:00

abstract：BACKGROUND:Human Enterovirus 71 (EV71) has emerged as the leading cause of viral encephalitis in children, especially in the Asia-Pacific regions. EV71 vaccine development is of high priority at present, and neutralization antibodies have been documented to play critical roles during in vitro and in vivo protection aga...

journal_title：Virology journal

authors： Li YX,Zhao H,Cao RY,Deng YQ,Han JF,Zhu SY,Ma J,Liu L,Qin ED,Qin CF

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Human enterovirus 71 (EV-71) is known of having caused numerous outbreaks of hand-foot-mouth disease, and other clinical manifestations globally. In 2008, 989 EV-71 strains were isolated in Taiwan. RESULTS:In this study, the genetic and antigenic properties of these strains were analyzed and the genetic div...

journal_title：Virology journal

authors： Huang YP,Lin TL,Hsu LC,Chen YJ,Tseng YH,Hsu CC,Fan WB,Yang JY,Chang FY,Wu HS

更新日期：2010-10-20 00:00:00

abstract：:Virology Journal is an exclusively on-line, Open Access journal devoted to the presentation of high-quality original research concerning human, animal, plant, insect bacterial, and fungal viruses. Virology Journal will establish a strategic alternative to the traditional virology communication process. ...

journal_title：Virology journal

authors： Garry RF

更新日期：2004-08-26 00:00:00

abstract：BACKGROUND:Double-stranded RNA (dsRNA) and its mimic, polyinosinic acid: polycytidylic acid [Poly (I:C)], are recognized by toll-like receptor 3 (TLR3) and induce interferon (IFN)-β in many cell types. Poly (I:C) is the most potent IFN inducer. In in vivo mouse studies, intraperitoneal injection of Poly (I:C) elicited ...

journal_title：Virology journal

authors： Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-Nuegoonpipat A,Pan Y,Kameoka M,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

更新日期：2012-06-14 00:00:00

abstract：BACKGROUND:Little is known at the molecular level concerning the differences and/or similarities between alcohol and hepatitis C virus induced liver disease. Global transcriptional profiling using oligonucleotide microarrays was therefore performed on liver biopsies from patients with cirrhosis caused by either chronic...

journal_title：Virology journal

authors： Lederer SL,Walters KA,Proll S,Paeper B,Robinzon S,Boix L,Fausto N,Bruix J,Katze MG

更新日期：2006-11-22 00:00:00

abstract：BACKGROUND:Viral delivery remains one of the most commonly used techniques today in the field of gene therapy. However, one of the remaining hurdles is the off-targeting effect of viral delivery. To overcome this obstacle, we recently developed a method to incorporate an antibody and a fusogenic molecule (FM) as two di...

journal_title：Virology journal

authors： Lei Y,Joo KI,Zarzar J,Wong C,Wang P

更新日期：2010-02-11 00:00:00

abstract：BACKGROUND:hyaluronic acid (HA), a non-sulphated glycosaminoglycan, is present in synovial fluid, vitreous humour serum and many connective tissues. Pharmaceutical preparations of HA are used in clinical practice for wound healing, joint pain, kerato-conjunctivitis, asthma, mouth care, oesophageal-reflux, and gastritis...

journal_title：Virology journal

authors： Cermelli C,Cuoghi A,Scuri M,Bettua C,Neglia RG,Ardizzoni A,Blasi E,Iannitti T,Palmieri B

更新日期：2011-03-25 00:00:00

abstract：:The I5L gene is one of approximately 90 genes that are conserved throughout the chordopoxvirus family, and hence are presumed to play vital roles in the poxvirus life cycle. Previous work had indicated that the VP13 protein, a component of the virion membrane, was encoded by the I5L gene, but no additional studies had...

journal_title：Virology journal

authors： Unger B,Nichols RJ,Stanitsa ES,Traktman P

更新日期：2008-12-15 00:00:00

abstract：:Hepatitis E virus (HEV) is a zoonotic pathogen of which several species of animal were reported as reservoirs. Swine stands out as the major reservoir for HEV infection in humans, as suggested by the close genetic relationship of swine and human virus and cross-species infection of HEV. Up to now, the mechanism of cro...

journal_title：Virology journal

authors： Zhang W,Hua X,Shen Q,Yang S,Yin H,Cui L

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:The pattern recognition receptors (PPRs) are the earliest phase of the host defense against pathogens in genital epithelium, and toll-like receptors (TLRs) are best characterized PPRs mediating innate immune responses. Herpes simplex virus type 2 (HSV-2), a member of herpesviridae family, causes one of the m...

journal_title：Virology journal

authors： Lv X,Wang H,Su A,Xu S,Chu Y

更新日期：2018-11-12 00:00:00

abstract：BACKGROUND:Although prophylactic vaccines have been developed against HPV6, HPV11, HPV16 and HPV18 there is the clear unmet medical need in order to justify the development of drugs targeting human papillomavirus replication. The native host cells of HPVs are human primary keratinocytes which can be cultivated in raft ...

journal_title：Virology journal

authors： Isok-Paas H,Männik A,Ustav E,Ustav M

更新日期：2015-04-14 00:00:00