Seewis virus, a genetically distinct hantavirus in the Eurasian common shrew (Sorex araneus).

abstract：BACKGROUND:The effect of antiviral therapy in chronic hepatitis B (CHB) on reducing the risk of long-term complications (LTCs) remains unclear so far. To study whether long-term nucleos(t)ide analogues therapy can reduce the risk of long-term complications. METHODS:We searched MEDLINE, EMBASE, OVID, the Cochrane Centr...

journal_title：Virology journal

authors： Zhang QQ,An X,Liu YH,Li SY,Zhong Q,Wang J,Hu HD,Zhang DZ,Ren H,Hu P

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression that correspond to that specific pathogen. Venezuelan equine encephalitis (VEE) is a mosquito-borne ...

journal_title：Virology journal

authors： Hammamieh R,Barmada M,Ludwig G,Peel S,Koterski N,Jett M

更新日期：2007-08-29 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are two of the most frequent respiratory pathogens that circulate worldwide. Infection with either virus can lead to hospitalization of young children, immunocompromised people and the elderly.A better understanding of the epidemiologi...

journal_title：Virology journal

authors： Sastre P,Ruiz T,Schildgen O,Schildgen V,Vela C,Rueda P

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) Core protein regulates multiple signaling pathways and alters cellular genes expression responsible for HCV induced pathogenesis leading to hepatocellular carcinoma (HCC). Prevalence of HCV genotype 3a associated HCC is higher in Pakistan as compare to the rest of world; however the m...

journal_title：Virology journal

authors： Jahan S,Khaliq S,Siddiqi MH,Ijaz B,Ahmad W,Ashfaq UA,Hassan S

更新日期：2011-11-23 00:00:00

abstract：BACKGROUND:Andes virus (ANDV), a rodent-borne Hantavirus, is the major etiological agent of Hantavirus cardiopulmonary syndrome (HCPS) in South America, which is mainly characterized by a vascular leakage with high rate of fatal outcomes for infected patients. Currently, neither specific therapy nor vaccines are availa...

journal_title：Virology journal

authors： Marsac D,García S,Fournet A,Aguirre A,Pino K,Ferres M,Kalergis AM,Lopez-Lastra M,Veas F

更新日期：2011-05-13 00:00:00

abstract：:Much of the worlds' population is in active or imminent danger from established infectious pathogens, while sporadic and pandemic infections by these and emerging agents threaten everyone. RNA polymerases (RNApol) generate enormous genetic and consequent antigenic heterogeneity permitting both viruses and cellular pat...

journal_title：Virology journal

authors： Sallie R

更新日期：2005-08-22 00:00:00

abstract：:Presumptive phage particles associated with Xylella fastidiosa strain Temecula-1 grown in PW broth were observed by transmission electron microscopy (TEM) in ultrathin sections of bacterial cell-containing low speed centrifugation pellets and in partially purified preparations from CsCl equilibrium centrifugation dens...

journal_title：Virology journal

authors： Chen J,Civerolo EL

更新日期：2008-06-06 00:00:00

abstract：BACKGROUND:The major structural protein of coronaviruses, the membrane (M) protein, can elicit the formation of protective antibodies, but little information is available about the M protein of porcine epidemic diarrhea virus (PEDV). Identification of epitopes on the PEDV M protein will be helpful in the elucidation of...

journal_title：Virology journal

authors： Zhang Z,Chen J,Shi H,Chen X,Shi D,Feng L,Yang B

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Rotavirus (RV) is the main cause of severe gastroenteritis in children. An effective vaccination regime against RV can substantially reduce morbidity and mortality. Previous studies have demonstrated the efficacy of virus-like particles formed by RV VP2 and VP6 (VLP2/6), as well as that of recombinant adenov...

journal_title：Virology journal

authors： Zhou H,Guo L,Wang M,Qu J,Zhao Z,Wang J,Hung T

更新日期：2011-01-05 00:00:00

abstract：BACKGROUND:Controversy remains as to whether antiviral agents contribute to renal dysfunction in patients with chronic hepatitis B virus (HBV) infection. Thus, the aim of study was to analyze the changes in renal function of chronic hepatitis B (CHB) patients in response to anti-HBV therapy and the association with tre...

journal_title：Virology journal

authors： Zhang Y,Zhang WL,Pang XW,Wang LX,Wei X,Huang CX,Bai XF,Han S,Liu LN,Lian JQ

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:The amino terminus of the tobacco etch virus (TEV) capsid protein is located on the external surface of infectious TEV particles, as proposed by previous studies and an in silico model. The epsilon amino groups on the exposed lysine residues are available for chemical conjugation to any given protein, and ca...

journal_title：Virology journal

authors： Manuel-Cabrera CA,Márquez-Aguirre A,Rodolfo HG,Ortiz-Lazareno PC,Chavez-Calvillo G,Carrillo-Tripp M,Silva-Rosales L,Gutiérrez-Ortega A

更新日期：2012-03-27 00:00:00

abstract：:The European swine influenza viruses (SIVs) show considerable diversity comprising different types of H1N1, H3N2, and H1N2 strains. The intensifying full genome sequencing efforts reveal further reassortants within these subtypes. Here we report the identification of an uncommon reassortant variant of H1N2 subtype inf...

journal_title：Virology journal

authors： Bálint A,Metreveli G,Widén F,Zohari S,Berg M,Isaksson M,Renström LH,Wallgren P,Belák S,Segall T,Kiss I

更新日期：2009-10-28 00:00:00

abstract：BACKGROUND:The threat of recurring influenza pandemics caused by new viral strains and the occurrence of escape mutants necessitate the search for potent therapeutic targets. The dependence of viruses on cellular factors provides a weak-spot in the viral multiplication strategy and a means to interfere with viral multi...

journal_title：Virology journal

authors： Sun L,Hemgård GV,Susanto SA,Wirth M

更新日期：2010-05-26 00:00:00

abstract：BACKGROUND:Host serine proteases are essential for the influenza virus life cycle because the viral haemagglutinin is synthesized as a precursor which requires proteolytic maturation. Therefore, we studied the activity and expression of serine proteases in lungs from mice infected with influenza and evaluated the effec...

journal_title：Virology journal

authors： Bahgat MM,Błazejewska P,Schughart K

更新日期：2011-01-20 00:00:00

abstract：CORRECTION:After publication of the article [1], it has been brought to our attention that an incorrect genetic sequence has been cited. On page 4, paragraph 1 the following sequence is cited "ATG GAT GCC GAC AAG ATT GTM TTY AAA GTY AAT A 3". This is an error and the correct sequence should be "GGG GGC TTT YCC TAG GGT ...

journal_title：Virology journal

authors： Schlottau K,Freuling CM,Müller T,Beer M,Hoffmann B

更新日期：2017-11-14 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is the most common cause of intrauterine infections worldwide. The toll-like receptors (TLRs) have been reported as important factors in immune response against HCMV. Particularly, TLR2, TLR4 and TLR9 have been shown to be involved in antiviral immunity. Evaluation of the role of...

journal_title：Virology journal

authors： Wujcicka W,Paradowska E,Studzińska M,Wilczyński J,Nowakowska D

更新日期：2017-03-24 00:00:00

abstract：BACKGROUND:Torque teno virus is a small chronically persisting circular negative ssDNA virus reaching near 100% prevalence. It is reported to be a marker for immune function in immunocompromised patients. The possibility of vertical maternal-fetal transmission remains controversial but incidence rate of TTV DNA in chil...

journal_title：Virology journal

authors： Tyschik EA,Rasskazova AS,Degtyareva AV,Rebrikov DV,Sukhikh GT

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population. Vaccination is the best strategy to control H5N1 HPAIV infection in poultry and transmission to human population. The aim of this study is to identif...

journal_title：Virology journal

authors： Zhang W,Tu J,Zhao Z,Chen H,Jin M

更新日期：2012-05-23 00:00:00

abstract：BACKGROUND:The mechanisms through which the avian influenza virus H5N1 modulate the host's innate immune defense during invasion, remains incompletely understood. RIG-I as a pattern recognition receptor plays an important role in mediating innate immune response induced by influenza virus. So, modulating RIG-I might be...

journal_title：Virology journal

authors： Mi Z,Ma Y,Tong Y

更新日期：2012-08-03 00:00:00

abstract：BACKGROUND:Recombinant Salmonella vaccine vectors may potentially be used to induce specific CD4+ T cell responses against foreign viral antigens. Such immune responses are required features of vaccines against pathogens such as human immunodeficiency virus type 1 (HIV-1). The aim of this study was to investigate the i...

journal_title：Virology journal

authors： Chin'ombe N,Bourn WR,Williamson AL,Shephard EG

更新日期：2009-06-25 00:00:00

abstract：BACKGROUND:Porcine circovirus type 2 (PCV2), the causative agent of postweaning multisystemic wasting syndrome (PMWS), is a serious economic problem in the swine industry. Different genotypes (PCV2a, PCV2b and PCV2d) of the virus are present in the clinical cases in China, and it is necessary to elucidate the pathogeni...

journal_title：Virology journal

authors： Guo LJ,Lu YH,Huang LP,Wei YW,Wu HL,Liu CM

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Human Enterovirus 71 (EV71) has emerged as the leading cause of viral encephalitis in children, especially in the Asia-Pacific regions. EV71 vaccine development is of high priority at present, and neutralization antibodies have been documented to play critical roles during in vitro and in vivo protection aga...

journal_title：Virology journal

authors： Li YX,Zhao H,Cao RY,Deng YQ,Han JF,Zhu SY,Ma J,Liu L,Qin ED,Qin CF

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Taiwan has been considered free from canine parvovirus type 2c (CPV-2c) based on the last report of canine parvovirus type 2 (CPV-2) surveillance. However, since January 2015, the first report of CPV-2c in a puppy has occurred in Taiwan. There is currently limited information about the CPV-2c variant in Taiw...

journal_title：Virology journal

authors： Chiang SY,Wu HY,Chiou MT,Chang MC,Lin CN

更新日期：2016-09-23 00:00:00

abstract：:The most common etiologic agents causing chronic hepatitis are hepatitis C and B viruses (HCV and HBV, respectively). Chronic infection caused by HCV is considered one of the major causative agents of liver cirrhosis and hepatocellular carcinoma worldwide. In combination with the increasing rate of new HCV infections,...

journal_title：Virology journal

authors： Hoffmann TW,Duverlie G,Bengrine A

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Newcastle disease (ND), caused by Newcastle disease virus (NDV), is a highly contagious disease of birds and has been one of the major causes of economic losses in the poultry industry. Despite routine vaccination programs, sporadic cases have occasionally occurred in the country and remain a constant threat...

journal_title：Virology journal

authors： Berhanu A,Ideris A,Omar AR,Bejo MH

更新日期：2010-08-08 00:00:00

abstract：BACKGROUND:Viral delivery remains one of the most commonly used techniques today in the field of gene therapy. However, one of the remaining hurdles is the off-targeting effect of viral delivery. To overcome this obstacle, we recently developed a method to incorporate an antibody and a fusogenic molecule (FM) as two di...

journal_title：Virology journal

authors： Lei Y,Joo KI,Zarzar J,Wong C,Wang P

更新日期：2010-02-11 00:00:00

abstract：BACKGROUND:Otitis media (OM) affects ≥80% of children before the age of three. OM can arise following co-infection with influenza A virus (IAV) and the bacterium Streptococcus pneumoniae. We have previously shown that H3 IAV strains (such as Udorn/72) induced a higher rate of bacterial OM than H1 strains (such as PR8/3...

journal_title：Virology journal

authors： Short KR,Habets MN,Payne J,Reading PC,Diavatopoulos DA,Wijburg OL

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:Previously, we showed that the tetraspanin membrane protein CD63 mediates both early and post-integration stages of the HIV-1 replication cycle. The temporal roles of CD63 were discerned using monoclonal antibodies and small interfering RNAs (siRNAs) to block CD63 function, and determining which of the seque...

journal_title：Virology journal

authors： Li G,Endsley MA,Somasunderam A,Gbota SL,Mbaka MI,Murray JL,Ferguson MR

更新日期：2014-02-08 00:00:00

abstract：BACKGROUND:Panicum streak virus (PanSV; Family Geminiviridae; Genus Mastrevirus) is a close relative of Maize streak virus (MSV), the most serious viral threat to maize production in Africa. PanSV and MSV have the same leafhopper vector species, largely overlapping natural host ranges and similar geographical distribut...

journal_title：Virology journal

authors： Varsani A,Monjane AL,Donaldson L,Oluwafemi S,Zinga I,Komba EK,Plakoutene D,Mandakombo N,Mboukoulida J,Semballa S,Briddon RW,Markham PG,Lett JM,Lefeuvre P,Rybicki EP,Martin DP

更新日期：2009-11-10 00:00:00

abstract：BACKGROUND:The diseases caused by Rice black streaked dwarf virus (RBSDV) and Southern rice black streaked dwarf virus (SRBSDV) have been occurring epidemically in China and southeastern Asia in recent years. A sensitive, reliable and quantitative method is required to detect and distinguish for RBSDV and SRBSDV in ric...

journal_title：Virology journal

authors： Zhang P,Mar TT,Liu W,Li L,Wang X

更新日期：2013-01-18 00:00:00