MicroRNAs and hepatitis C virus: toward the end of miR-122 supremacy.

abstract：BACKGROUND:Hepatitis B virus (HBV) can be classified into nine genotypes (A-I) defined by sequence divergence of more than 8% based on the complete genome. This study aims to identify the genotypic distribution of HBV in 40 HBsAg-positive patients from Rondônia, Brazil. A fragment of 1306 bp partially comprising surfac...

journal_title：Virology journal

authors： Santos AO,Alvarado-Mora MV,Botelho L,Vieira DS,Pinho JR,Carrilho FJ,Honda ER,Salcedo JM

更新日期：2010-11-12 00:00:00

abstract：:The prevalence of North American orthopoxviruses in nature is unknown and may be more difficult to ascertain due to wide spread use of vaccinia virus recombinant vaccines in the wild. A real time PCR assay was developed to allow for highly sensitive and specific detection of North American orthopoxvirus DNA in animal ...

journal_title：Virology journal

authors： Gallardo-Romero NF,Velasco-Villa A,Weiss SL,Emerson GL,Carroll DS,Hughes CM,Li Y,Karem KL,Damon IK,Olson VA

更新日期：2011-06-20 00:00:00

abstract：BACKGROUND:The threat of recurring influenza pandemics caused by new viral strains and the occurrence of escape mutants necessitate the search for potent therapeutic targets. The dependence of viruses on cellular factors provides a weak-spot in the viral multiplication strategy and a means to interfere with viral multi...

journal_title：Virology journal

authors： Sun L,Hemgård GV,Susanto SA,Wirth M

更新日期：2010-05-26 00:00:00

abstract：BACKGROUND:Xenotransplantation using pig cells, tissues and organs may help to overcome the shortage of human tissues and organs for the treatment of tissue and organ failure. Progress in the prevention of immunological rejection using genetically modified pigs and new, more effective, immunosuppression regimens will a...

journal_title：Virology journal

authors： Denner J

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:Endometrial cancer (EC) is one of the most common gynecological malignancies globally. Although progress has been made in surgical and other adjuvant therapies, there is still a great need to develop new approaches to further reduce the incidence and mortality of EC. Oncolytic virotherapy offers a novel prom...

journal_title：Virology journal

authors： Lin Y,Wang W,Wan J,Yang Y,Fu W,Pan D,Cai L,Cheng T,Huang X,Wang Y

更新日期：2018-04-10 00:00:00

abstract：:We report the presence of three new O1 ElTor vibriophages named AS1, AS2 and AS3, isolated from the sewage and pond waters of the outskirts of Kolkata. A few phages, named AS4, with hexagonal heads and abnormally long tails with typical curly projections were also found in the water samples. ...

journal_title：Virology journal

authors： Sen A,Ghosh AN

更新日期：2005-04-11 00:00:00

abstract：BACKGROUND:An HIV cure has not yet been achieved because latent viral reservoirs persist, particularly in resting CD4+ T lymphocytes. In vitro, it is difficult to infect resting CD4+ T cells with HIV-1, but infections readily occur in vivo. Endothelial cells (EC) line the lymphatic vessels in the lymphoid tissues and r...

journal_title：Virology journal

authors： Schilthuis M,Verkaik S,Walhof M,Philipose A,Harlow O,Kamp D,Kim BR,Shen A

更新日期：2018-10-03 00:00:00

abstract：BACKGROUND:Pear ring rot, caused by Botryosphaeria species, is responsible for substantial economic losses by causing severe recession of pear tree growth in China. Mycovirus-mediated hypovirulence in plant pathogenic fungi is a crucial biological method to control fungal diseases. METHODS:We conducted a large-scale a...

journal_title：Virology journal

authors： Wang L,Luo H,Hu W,Yang Y,Hong N,Wang G,Wang A,Wang L

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:Dengue has emerged as the most significant of arboviral diseases in the 21st century. It is endemic to >100 tropical and sub-tropical countries around the world placing an estimated 3.6 billion people at risk. It is caused by four genetically similar but antigenically distinct, serotypes of dengue viruses. T...

journal_title：Virology journal

authors： Raut R,Beesetti H,Tyagi P,Khanna I,Jain SK,Jeankumar VU,Yogeeswari P,Sriram D,Swaminathan S

更新日期：2015-02-08 00:00:00

abstract：BACKGROUND:At the moment, there are a number of publications describing gene expression profiling in virus-infected plants. Most of the data are limited to specific host-pathogen interactions involving a given virus and a model host plant - usually Arabidopsis thaliana. Even though several summarizing attempts have bee...

journal_title：Virology journal

authors： Postnikova OA,Nemchinov LG

更新日期：2012-05-29 00:00:00

abstract：BACKGROUND:hyaluronic acid (HA), a non-sulphated glycosaminoglycan, is present in synovial fluid, vitreous humour serum and many connective tissues. Pharmaceutical preparations of HA are used in clinical practice for wound healing, joint pain, kerato-conjunctivitis, asthma, mouth care, oesophageal-reflux, and gastritis...

journal_title：Virology journal

authors： Cermelli C,Cuoghi A,Scuri M,Bettua C,Neglia RG,Ardizzoni A,Blasi E,Iannitti T,Palmieri B

更新日期：2011-03-25 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) congenital infection is the major viral cause of well-documented birth defects in human. Because CMV is species-specific, the main obstacle to developing animal models for congenital infection is the difference in placental architecture, which preludes virus transmission across the plac...

journal_title：Virology journal

authors： Loh HS,Mohd-Lila MA,Abdul-Rahman SO,Kiew LJ

更新日期：2006-06-01 00:00:00

abstract：:Human cytomegalovirus (HCMV), a member of the Betaherpesvirinae sub-family of Herpesviridae family, is a widespread pathogen that infects a majority of the world's population by early adulthood. In individuals whose immune systems are immature or weakened, HCMV is a significant pathogen causing morbidity and mortality...

journal_title：Virology journal

authors： Tomtishen JP 3rd

更新日期：2012-01-17 00:00:00

abstract：:A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV infected patients also contains a heterogeneous population of wild-type and mutant 3a transcripts...

journal_title：Virology journal

authors： Tan TH,Barkham T,Fielding BC,Chou CF,Shen S,Lim SG,Hong W,Tan YJ

更新日期：2005-06-20 00:00:00

abstract：BACKGROUND:The major structural protein of coronaviruses, the membrane (M) protein, can elicit the formation of protective antibodies, but little information is available about the M protein of porcine epidemic diarrhea virus (PEDV). Identification of epitopes on the PEDV M protein will be helpful in the elucidation of...

journal_title：Virology journal

authors： Zhang Z,Chen J,Shi H,Chen X,Shi D,Feng L,Yang B

更新日期：2012-10-01 00:00:00

abstract：:Virus taxonomy at present is best characterized as a categorization of convenience, without a firm basis in the principles of evolutionary biology. Specifically, virus species definitions appear to depend more on tradition and popular opinion among virologists than on firm, quantitative biological evidence. I suggest ...

journal_title：Virology journal

authors： Peterson AT

更新日期：2014-07-23 00:00:00

abstract：BACKGROUND:Foot-and mouth disease (FMD) is an acute, febrile, and contagious vesicular disease affecting cloven-hoofed animals. Some animals may become persistent infected carriers when they contact FMD virus (FMDV), and persistent infected animals are a dangerous factor to cause FMD outbreak. FINDINGS:300 OP (oesopha...

journal_title：Virology journal

authors： Bao HF,Li D,Sun P,Zhou Q,Hu J,Bai XW,Fu YF,Lu ZJ,Liu ZX

更新日期：2011-12-14 00:00:00

abstract：:During the outbreak of SARS in 2002/3, a prototype virus was isolated from a patient in Frankfurt/Germany (strain Frankfurt-1). As opposed to all other SARS-Coronavirus strains, Frankfurt-1 has a 45-nucleotide deletion in the transmembrane domain of its ORF 7b protein. When over-expressed in HEK 293 cells, the full-le...

journal_title：Virology journal

authors： Pfefferle S,Krähling V,Ditt V,Grywna K,Mühlberger E,Drosten C

更新日期：2009-08-24 00:00:00

abstract：BACKGROUND:Pseudocowpox virus (PCPV) infects cattle worldwide with zoonotic potential but has not been isolated in Japan. Thus, the epidemiological status of PCPV infection in cattle is undetermined. RESULTS:In May 2016, a cattle in a farm in Yamaguchi Prefecture showed white vesicles and hyperemia in the mucosa under...

journal_title：Virology journal

authors： Ohtani A,Yokoyama A,Narushige H,Inoshima Y

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Tanganya virus (TGNV), the only shrew-associated hantavirus reported to date from sub-Saharan Africa, is harbored by the Therese's shrew (Crocidura theresae), and is phylogenetically distinct from Thottapalayam virus (TPMV) in the Asian house shrew (Suncus murinus) and Imjin virus (MJNV) in the Ussuri white-...

journal_title：Virology journal

authors： Kang HJ,Kadjo B,Dubey S,Jacquet F,Yanagihara R

更新日期：2011-07-28 00:00:00

abstract：:Retroviral transduction involves integrase-dependent linkage of viral and host DNA that leaves an intermediate that requires post-integration repair (PIR). We and others proposed that PIR hijacks the host cell double-strand DNA break (DSB) repair pathways. Nevertheless, the geometry of retroviral DNA integration diffe...

journal_title：Virology journal

authors： Smith JA,Wang FX,Zhang H,Wu KJ,Williams KJ,Daniel R

更新日期：2008-01-22 00:00:00

abstract：:Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most important emerging diseases that have no available treatment to date. In recent yea...

journal_title：Virology journal

authors： García LL,Padilla L,Castaño JC

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:Taiwan has been considered free from canine parvovirus type 2c (CPV-2c) based on the last report of canine parvovirus type 2 (CPV-2) surveillance. However, since January 2015, the first report of CPV-2c in a puppy has occurred in Taiwan. There is currently limited information about the CPV-2c variant in Taiw...

journal_title：Virology journal

authors： Chiang SY,Wu HY,Chiou MT,Chang MC,Lin CN

更新日期：2016-09-23 00:00:00

abstract：BACKGROUND:Most of the non-B HIV-1 subtypes are predominant in Sub-Saharan Africa and India although they have been found worldwide. In the last decade, immigration from these areas has increased considerably in Spain. The objective of this study was to evaluate the prevalence of non-B subtypes circulating in a cohort ...

journal_title：Virology journal

authors： de Felipe B,Pérez-Romero P,Abad-Fernández M,Fernandez-Cuenca F,Martinez-Fernandez FJ,Trastoy M,Mata Rdel C,López-Cortés LF,Leal M,Viciana P,Vallejo A

更新日期：2011-08-26 00:00:00

abstract：:Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial and complete structures of nine out of twenty tail structural p...

journal_title：Virology journal

authors： Leiman PG,Arisaka F,van Raaij MJ,Kostyuchenko VA,Aksyuk AA,Kanamaru S,Rossmann MG

更新日期：2010-12-03 00:00:00

abstract：BACKGROUND:HIV infection of cells varies greatly between individuals, with multiple steps in the replication cycle potentially contributing to the variability. Although entry and post-entry variability of HIV infection levels in cells has been demonstrated, variability in HIV binding has not been examined. In this stud...

journal_title：Virology journal

authors： Anzinger JJ,Olinger GG,Spear GT

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:Clinical and laboratory studies have indicated that coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) can suppress one another, eliciting a dominant disease phenotype. To assess whether HBV can influence the antiviral effect of treatment on HCV, we performed a meta-analysis to comparativel...

journal_title：Virology journal

authors： Liu JY,Sheng YJ,Hu HD,Zhong Q,Wang J,Tong SW,Zhou Z,Zhang DZ,Hu P,Ren H

更新日期：2012-09-06 00:00:00

abstract：BACKGROUND:Bovine viral diarrhea virus (BVDV) infections continue to cause significantly losses in the deer population. Better isolation and identification of BVDV from sika deer may contribute significantly to the development of prophylactic therapeutic, and diagnostic reagents as well as help in prevention and contro...

journal_title：Virology journal

authors： Gao Y,Wang S,Du R,Wang Q,Sun C,Wang N,Zhang P,Zhang L

更新日期：2011-02-25 00:00:00

abstract：BACKGROUND:Tomato leaf curl virus (ToLCV), a constituent of the genus Begomovirus, infects tomato and other plants with a hallmark disease symptom of upward leaf curling. Since microRNAs (miRs) are known to control plants developmental processes, we evaluated the roles of miRNAs in Tomato leaf curl New Delhi virus (ToL...

journal_title：Virology journal

authors： Naqvi AR,Haq QM,Mukherjee SK

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:LIN28B is involved in multiple cellular developmental processes, tissue inflammatory response and tumourigenesis. The association of LIN28B polymorphisms with hepatitis B virus (HBV) infection remains unknown. METHODS:This study investigated the association of LIN28B rs314277, rs314280, rs369065 and rs77599...

journal_title：Virology journal

authors： Han Q,Sang J,Fan X,Wang X,Zeng L,Zhang X,Zhang K,Li N,Lv Y,Liu Z

更新日期：2020-06-22 00:00:00