Abstract:
:Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most important emerging diseases that have no available treatment to date. In recent years, the strategy has focused on the development of replication inhibitors of these viruses designed to act mainly by affecting the activity of enzyme proteins, such as NS3 and NS5, which perform important functions in the viral replication process. This article describes the importance of flaviviruses and the development of molecules used as inhibitors of viral replication in this genus.
journal_name
Virol Jjournal_title
Virology journalauthors
García LL,Padilla L,Castaño JCdoi
10.1186/s12985-017-0761-1subject
Has Abstractpub_date
2017-05-15 00:00:00pages
95issue
1issn
1743-422Xpii
10.1186/s12985-017-0761-1journal_volume
14pub_type
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