Abstract:
:Increasing infections with Monkeypox and Cowpox viruses pose a continuous and growing threat to human health. The standard method for detecting poxvirus neutralizing antibodies is the plaque-reduction neutralization test that is specific but also time-consuming and laborious. Therefore, a rapid and reliable method was developed to determine neutralizing antibody titers within twelve hours. The new assay measures viral mRNA transcription as a marker for actively replicating virus after incomplete neutralization using real-time PCR.
journal_name
Virol Jjournal_title
Virology journalauthors
Kramski M,Drozd A,Lichtfuss GF,Dabrowski PW,Ellerbrok Hdoi
10.1186/1743-422X-8-139subject
Has Abstractpub_date
2011-03-25 00:00:00pages
139issn
1743-422Xpii
1743-422X-8-139journal_volume
8pub_type
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