Evaluation of nanoparticle tracking analysis for total virus particle determination.

abstract：BACKGROUND:With the clinical development of several antiviral intervention strategies for influenza, it becomes crucial to explore viral load shedding in the nasal cavity as a biomarker for treatment success, but also to explore sampling strategies for sensible and reliable virus collection. FINDINGS:In this study, 24...

journal_title：Virology journal

authors： Van Wesenbeeck L,Meeuws H,D'Haese D,Ispas G,Houspie L,Van Ranst M,Stuyver LJ

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:RNA viruses are characterized by high rate of mutations mainly due to the lack of proofreading repair activities associated with its RNA-dependent RNA-polymerase (RdRp). In case of arboviruses, this phenomenon has lead to the existence of mixed population of genomic variants within the host called quasi-spec...

journal_title：Virology journal

authors： Jain J,Mathur K,Shrinet J,Bhatnagar RK,Sunil S

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:The genus Flavivirus includes several pathogenic agents that cause severe illness in humans. Re-emergence of West Nile virus in Europe and continuous spread of certain flaviviruses such as dengue, yellow fever and Japanese encephalitis viruses represent a global danger to public health. Therefore, a rapid an...

journal_title：Virology journal

authors： Patel P,Landt O,Kaiser M,Faye O,Koppe T,Lass U,Sall AA,Niedrig M

更新日期：2013-02-14 00:00:00

abstract：BACKGROUND:We have characterised a new highly divergent geminivirus species, Eragrostis curvula streak virus (ECSV), found infecting a hardy perennial South African wild grass. ECSV represents a new genus-level geminivirus lineage, and has a mixture of features normally associated with other specific geminivirus genera...

journal_title：Virology journal

authors： Varsani A,Shepherd DN,Dent K,Monjane AL,Rybicki EP,Martin DP

更新日期：2009-03-25 00:00:00

abstract：BACKGROUND:Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (UL) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, we constructed a deletion mutant of ORF58 (pOka-BACDelta58) from the Oka parental genome cloned i...

journal_title：Virology journal

authors： Yoshii H,Sadaoka K,Matsuura M,Nagaike K,Takahashi M,Yamanishi K,Mori Y

更新日期：2008-04-30 00:00:00

abstract：BACKGROUND:Uukuniemi virus (UUKV) belongs to the Phlebovirus genus in the family Bunyaviridae. As a non-pathogenic virus for humans UUKV has served as a safe model bunyavirus in a number of studies addressing fundamental questions such as organization and regulation of viral genes, genome replication, structure and ass...

journal_title：Virology journal

authors： Katz A,Freiberg AN,Backström V,Schulz AR,Mateos A,Holm L,Pettersson RF,Vaheri A,Flick R,Plyusnin A

更新日期：2010-08-10 00:00:00

abstract：:Guards of Cyprian honey bee colonies, Apis mellifera cypria, display a great defensive behaviour against hornets' attacks. The deformed wing virus (DWV) and the kakugo virus (KV) genomes are very similar, but unlike KV, the presence of DWV is not related to honey bees' aggressiveness. This discrepancy is further discu...

journal_title：Virology journal

authors： Rortais A,Tentcheva D,Papachristoforou A,Gauthier L,Arnold G,Colin ME,Bergoin M

更新日期：2006-08-30 00:00:00

abstract：:We undertook one of the most detailed studies on the distribution of alpha2,3 sialic acid (SA)-galactose (gal) (avian type) and alpha2,6SA-gal (human type) receptors on different tissues of chickens, ducks and turkeys of varying age groups. On the tracheal epithelium, all 3 bird species expressed strong positive stain...

journal_title：Virology journal

authors： Pillai SP,Lee CW

更新日期：2010-01-12 00:00:00

abstract：BACKGROUND:The influenza RNA dependent RNA polymerase synthesizes viral RNA in the nucleus as functional viral ribonucleoprotein (vRNP) complexes with RNA and nucleoprotein (NP). The N-terminus of NP contains an unconventional nuclear localization signal (NLS) important for initial vRNP nuclear localization but which a...

journal_title：Virology journal

authors： Sanchez A,Guerrero-Juarez CF,Ramirez J,Newcomb LL

更新日期：2014-08-31 00:00:00

abstract：BACKGROUND:Using a murine model of parainfluenza virus infection (mPIV1 or Sendai virus; SeV), we compared the inflammatory responses to lethal and sub-lethal infections in inbred DBA/2 mice. METHODS:Mice were intranasally inoculated with either 1.6×10(3) or 1.6×10(5) infectious units (IU) of SeV or diluent control. C...

journal_title：Virology journal

authors： Suryadevara M,Bonville CA,Rosenberg HF,Domachowske JB

更新日期：2013-12-21 00:00:00

abstract：:Hepatitis C virus (HCV) is endemic worldwide, and it causes cirrhosis and other complications that often lead to death; nevertheless, our knowledge of the disease and its mechanisms is limited. HCV is most common in underdeveloped nations, including many in Africa and Asia. The virus is usually transmitted by parenter...

journal_title：Virology journal

authors： Aman W,Mousa S,Shiha G,Mousa SA

更新日期：2012-03-02 00:00:00

abstract：:We describe an improvement of an earlier reported real-time RT-PCR assay for the detection of enterovirus RNA, based on the 5' exonuclease digestion of a dual-labeled fluorogenic probe by Taq DNA polymerase. A different extraction method, real-time RT-PCR instrument and primer set were evaluated. Our data show that th...

journal_title：Virology journal

authors： Piqueur MA,Verstrepen WA,Bruynseels P,Mertens AH

更新日期：2009-07-07 00:00:00

abstract：BACKGROUND:R849 is a neurovirulent γ₁34.5 gene-deficient form of herpes simplex virus type 1 (HSV-1) and has LacZ genes at the deleted sites of the γ₁34.5 gene. HF is a spontaneously occurring, fusogenic HSV-1 strain. The purpose of this work was to generate a virus that has the syncytial character of HF, while preserv...

journal_title：Virology journal

authors： Takaoka H,Takahashi G,Ogawa F,Imai T,Iwai S,Yura Y

更新日期：2011-06-10 00:00:00

abstract：:A previous study has identified two types of recombinant variants of Potato virus Y strain NTN (PVY(NTN)) in China and sequenced the complete genome of the variant PVY(NTN)-HN2. In this study, the complete genome of isolate PVY(NTN)-HN1 was fully sequenced and analyzed. The most striking difference between the two var...

journal_title：Virology journal

authors： Hu X,Nie X,He C,Xiong X

更新日期：2011-05-07 00:00:00

abstract：BACKGROUND:Infection with H5N1 highly pathogenic avian influenza viruses (HPAIVs) of domestic poultry and wild birds has spread to more than 60 countries in Eurasia and Africa. It is concerned that HPAIVs may be perpetuated in the lakes in Siberia where migratory water birds nest in summer. To monitor whether HPAIVs ci...

journal_title：Virology journal

authors： Yamamoto N,Sakoda Y,Motoshima M,Yoshino F,Soda K,Okamatsu M,Kida H

更新日期：2011-02-11 00:00:00

abstract：BACKGROUND:Xenotransplantation using pig cells, tissues and organs may help to overcome the shortage of human tissues and organs for the treatment of tissue and organ failure. Progress in the prevention of immunological rejection using genetically modified pigs and new, more effective, immunosuppression regimens will a...

journal_title：Virology journal

authors： Denner J

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:Cervical cancer is a major public health problem worldwide. While Romania has the highest incidence of cervical cancer in Europe, the prevalence of HPV has not been evaluated. We report the first data on HPV prevalence and type distribution in Northeast Romania. METHODS:HPV prevalence and genotype distribut...

journal_title：Virology journal

authors： Ursu RG,Onofriescu M,Nemescu D,Iancu LS

更新日期：2011-12-22 00:00:00

abstract：BACKGROUND:There are over 100 known human adenovirus (HAdV) types, which are able to cause a broad variety of different self-limiting but also lethal diseases especially in immunocompromised patients. Only limited information about the pathogenesis and biology of the majority of these virus types is available. In the p...

journal_title：Virology journal

authors： Mese K,Bunz O,Schellhorn S,Volkwein W,Jung D,Gao J,Zhang W,Baiker A,Ehrhardt A

更新日期：2020-04-09 00:00:00

abstract：BACKGROUND:Pear ring rot, caused by Botryosphaeria species, is responsible for substantial economic losses by causing severe recession of pear tree growth in China. Mycovirus-mediated hypovirulence in plant pathogenic fungi is a crucial biological method to control fungal diseases. METHODS:We conducted a large-scale a...

journal_title：Virology journal

authors： Wang L,Luo H,Hu W,Yang Y,Hong N,Wang G,Wang A,Wang L

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:To construct a recombinant adenovirus containing CDglyTK double suicide genes and evaluate the killing effect of the double suicide genes driven by kinase domain insert containing receptor (KDR) promoter on human umbilical vein endothelial cells. METHODS:Human KDR promoter, Escherichia coli (E. coli) cytosi...

journal_title：Virology journal

authors： Jia W,Mei L,Wang Y,Liu L,Che G

更新日期：2011-02-21 00:00:00

abstract：BACKGROUND:The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. METHODS:The safety of LSDV was tested at doses of 104 and 106 plaque forming units in two strains of i...

journal_title：Virology journal

authors： Shen YJ,Shephard E,Douglass N,Johnston N,Adams C,Williamson C,Williamson AL

更新日期：2011-05-30 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) has a causal role in cervical cancer with almost half a million new cases occurring each year. Presence of the carcinogenic HPV is necessary for the development of the invasive carcinoma of the genital tract. Therefore, persistent infection with carcinogenic HPV causes virtually al...

journal_title：Virology journal

authors： Angulo M,Carvajal-Rodríguez A

更新日期：2007-03-28 00:00:00

abstract：BACKGROUND:Highly-pathogenic avian influenza (HPAI) H5N1 and Newcastle disease (ND) viruses are the two most important poultry viruses in the world, with the ability to cause classic central nervous system dysfunction in poultry and migratory birds. To elucidate the mechanisms of neurovirulence caused by these viruses,...

journal_title：Virology journal

authors： Balasubramaniam VR,Wai TH,Omar AR,Othman I,Hassan SS

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:Endometrial cancer (EC) is one of the most common gynecological malignancies globally. Although progress has been made in surgical and other adjuvant therapies, there is still a great need to develop new approaches to further reduce the incidence and mortality of EC. Oncolytic virotherapy offers a novel prom...

journal_title：Virology journal

authors： Lin Y,Wang W,Wan J,Yang Y,Fu W,Pan D,Cai L,Cheng T,Huang X,Wang Y

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:T4 phage is a model species that has contributed broadly to our understanding of molecular biology. T4 DNA replication and packaging share various mechanisms with human double-stranded DNA viruses such as herpes virus. The literature indicates that T4-like phage genomes have permuted terminal sequences, and ...

journal_title：Virology journal

authors： Jiang X,Jiang H,Li C,Wang S,Mi Z,An X,Chen J,Tong Y

更新日期：2011-04-27 00:00:00

abstract：BACKGROUND:Nipah virus (NiV) is a zoonotic virus belonging to the henipavirus genus in the family Paramyxoviridae. Since NiV was first identified in 1999, outbreaks have continued to occur in humans in Bangladesh and India on an almost annual basis with case fatality rates reported between 40% and 100%. METHODS:Ferret...

journal_title：Virology journal

authors： Pallister JA,Klein R,Arkinstall R,Haining J,Long F,White JR,Payne J,Feng YR,Wang LF,Broder CC,Middleton D

更新日期：2013-07-16 00:00:00

abstract：BACKGROUND:H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China, a crucial stopover or wintering site for migratory wild birds along the East As...

journal_title：Virology journal

authors： Hu C,Li X,Zhu C,Zhou F,Tang W,Wu D,Li Z,Zhou L,Liu J,Wei X,Cui J,Wang T,He G

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Clinical and laboratory studies have indicated that coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) can suppress one another, eliciting a dominant disease phenotype. To assess whether HBV can influence the antiviral effect of treatment on HCV, we performed a meta-analysis to comparativel...

journal_title：Virology journal

authors： Liu JY,Sheng YJ,Hu HD,Zhong Q,Wang J,Tong SW,Zhou Z,Zhang DZ,Hu P,Ren H

更新日期：2012-09-06 00:00:00

abstract：BACKGROUND:Patchouli alcohol (PA) is a tricyclic sesquiterpene extracted from Pogostemonis Herba, which is a traditional Chinese medicine used for therapy of inflammatory diseases. Recent studies have shown that PA has various pharmacological activities, including anti-bacterial and anti-viral effects. METHODS:In this...

journal_title：Virology journal

authors： Yu Y,Zhang Y,Wang S,Liu W,Hao C,Wang W

更新日期：2019-12-23 00:00:00

abstract：:Hairpin RNAs have been used to confer resistance to viruses in plants through RNA silencing. However, it has not been demonstrated that RNA silencing was effective against inoculation by aphids of non-persistently transmitted viruses, the major route of plant virus spread in nature. As a proof-of-principle strategy, w...

journal_title：Virology journal

authors： Vargas M,Martínez-García B,Díaz-Ruíz JR,Tenllado F

更新日期：2008-03-19 00:00:00