The influence of hepatitis B virus on antiviral treatment with interferon and ribavirin in Asian patients with hepatitis C virus/hepatitis B virus coinfection: a meta-analysis.

abstract：BACKGROUND:Recent studies have revealed that Mitochondrial Antiviral Signaling (MAVS) protein plays an essential role in the inhibition of viral infection through type I interferon (IFN) pathway. It has been shown that 3C (pro) cysteine protease of coxsackievirus B3 (CVB3) cleaves MAVS to inhibit type I IFNs induction....

journal_title：Virology journal

authors： Zhang QM,Song WQ,Li YJ,Qian J,Zhai AX,Wu J,Li AM,He JM,Zhao JY,Yu X,Wei LL,Zhang FM

更新日期：2012-12-19 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in situations where the immune system is immature or compromised. HCMV immediate early (IE) gene expression is stimulated by the virion phosphoprotein pp71, encoded by open reading frame (ORF) UL82, and this transactivation activity...

journal_title：Virology journal

authors： Nicholson IP,Sutherland JS,Chaudry TN,Blewett EL,Barry PA,Nicholl MJ,Preston CM

更新日期：2009-05-27 00:00:00

abstract：BACKGROUND:The recent 2009 (H1N1) influenza A pandemic saw a rapid spread of the virus to essentially all parts of the world. In the course of its evolution, the virus acquired many mutations, some of which have been investigated in the context of increased severity due to high occurrences in fatal cases. For example, ...

journal_title：Virology journal

authors： Lee RT,Santos CL,de Paiva TM,Cui L,Sirota FL,Eisenhaber F,Maurer-Stroh S

更新日期：2010-11-01 00:00:00

abstract：:Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most important emerging diseases that have no available treatment to date. In recent yea...

journal_title：Virology journal

authors： García LL,Padilla L,Castaño JC

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:Chronic viral hepatitis B remains a global public health concern. Currently, several drugs, such as lamivudine and telbivudine, are recommended for treatment of patients with chronic hepatitis B. However, there are no conclusive results on the comparison of the efficacy of lamivudine (LAM) and telbivudine (L...

journal_title：Virology journal

authors： Zhao S,Tang L,Fan X,Chen L,Zhou R,Dai X

更新日期：2010-09-03 00:00:00

abstract：BACKGROUND:The gut microbiome is closely associated with the health of the host; although the interaction between the bacterial microbiome and the whole virome has rarely been studied, it is likely of medical importance. Examination of the interactions between the gut bacterial microbiome and virome of rhesus monkey wo...

journal_title：Virology journal

authors： Li H,Li H,Wang J,Guo L,Fan H,Zheng H,Yang Z,Huang X,Chu M,Yang F,He Z,Li N,Yang J,Wu Q,Shi H,Liu L

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and sub-tropical countries, affecting about 50 million people around the world yearly. In Colombia, dengue virus was first detected in 1971 and still remains as a major public health issue. Although four viral serotyp...

journal_title：Virology journal

authors： Méndez JA,Usme-Ciro JA,Domingo C,Rey GJ,Sánchez JA,Tenorio A,Gallego-Gomez JC

更新日期：2012-03-09 00:00:00

abstract：:The European swine influenza viruses (SIVs) show considerable diversity comprising different types of H1N1, H3N2, and H1N2 strains. The intensifying full genome sequencing efforts reveal further reassortants within these subtypes. Here we report the identification of an uncommon reassortant variant of H1N2 subtype inf...

journal_title：Virology journal

authors： Bálint A,Metreveli G,Widén F,Zohari S,Berg M,Isaksson M,Renström LH,Wallgren P,Belák S,Segall T,Kiss I

更新日期：2009-10-28 00:00:00

abstract：BACKGROUND:Although prophylactic vaccines have been developed against HPV6, HPV11, HPV16 and HPV18 there is the clear unmet medical need in order to justify the development of drugs targeting human papillomavirus replication. The native host cells of HPVs are human primary keratinocytes which can be cultivated in raft ...

journal_title：Virology journal

authors： Isok-Paas H,Männik A,Ustav E,Ustav M

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:The family Mesoniviridae (order Nidovirales) comprises of a group of positive-sense, single-stranded RNA ([+]ssRNA) viruses isolated from mosquitoes. FINDINGS:Thirteen novel insect-specific virus isolates were obtained from mosquitoes collected in Indonesia, Thailand and the USA. By electron microscopy, the...

journal_title：Virology journal

authors： Vasilakis N,Guzman H,Firth C,Forrester NL,Widen SG,Wood TG,Rossi SL,Ghedin E,Popov V,Blasdell KR,Walker PJ,Tesh RB

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:Some genotypes of human papillomaviruses can infect the genital tract and they are important infectious agents which their oncogenicity is regardable. Thus the aim of this study was to determine the prevalence of various genital human papillomaviruses (HPV) among women being subjected to routine pap smear te...

journal_title：Virology journal

authors： Zandi K,Eghbali SS,Hamkar R,Ahmadi S,Ramedani E,Deilami I,Nejad HA,Farshadpour F,Rastian Z

更新日期：2010-03-22 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus. Previous studies have identified neutralizing antibodies from Zika patients that bind to quaternary epitopes across neighboring envelope (E) proteins, called E dimer epitopes (EDE). An asparagine-linked glycan on the "glycan loop...

journal_title：Virology journal

authors： Henderson EA,Tam CC,Cheng LW,Ngono AE,Nguyen AV,Shresta S,McGee M,Padgett H,Grill LK,Martchenko Shilman M

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is of growing concern in public health with around 350 million chronically infected individuals worldwide. Although the IFN-alpha/rivabirin is the only approved therapy with 10-30% clinical efficacy, the protective molecular mechanism involved during the treatment is still u...

journal_title：Virology journal

authors： Gómez CE,Vandermeeren AM,García MA,Domingo-Gil E,Esteban M

更新日期：2005-09-12 00:00:00

abstract：BACKGROUND:Otitis media (OM) affects ≥80% of children before the age of three. OM can arise following co-infection with influenza A virus (IAV) and the bacterium Streptococcus pneumoniae. We have previously shown that H3 IAV strains (such as Udorn/72) induced a higher rate of bacterial OM than H1 strains (such as PR8/3...

journal_title：Virology journal

authors： Short KR,Habets MN,Payne J,Reading PC,Diavatopoulos DA,Wijburg OL

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:The genetic element s2m seems to represent one of very few examples of mobile genetic elements in viruses. The function remains obscure and a scattered taxonomical distribution has been reported by numerous groups. METHODS:We have searched GenBank in order to identify all viral accessions that have s2m(-lik...

journal_title：Virology journal

authors： Tengs T,Kristoffersen AB,Bachvaroff TR,Jonassen CM

更新日期：2013-04-25 00:00:00

abstract：:On 11 March 2020, the World Health Organization (WHO) announced Corona Virus Disease (COVID-19), a disease caused by a pathogen called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pandemic. This ongoing pandemic has now been reported in 215 countries with more than 23 million confirmed cases and mor...

journal_title：Virology journal

authors： Kiros M,Andualem H,Kiros T,Hailemichael W,Getu S,Geteneh A,Alemu D,Abegaz WE

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:Human T-cell Leukemia Virus type 1 (HTLV-1) is the etiological agent of tropical spastic paraparesis/HTLV-associated myelopathy (HAM/TSP) that can be identified in around 0.25%-3.8% of the infected population. Disease progression can be monitored by the proviral load and may depend on genetic factors, howeve...

journal_title：Virology journal

authors： Mota-Miranda AC,Barreto FK,Amarante MF,Batista E,Monteiro-Cunha JP,Farre L,Galvão-Castro B,Alcantara LC

更新日期：2013-03-06 00:00:00

abstract：BACKGROUND:Ticks are implicated as hosts to a wide range of animal and human pathogens. The full range of microbes harbored by ticks has not yet been fully explored. METHODS:As part of a viral surveillance and discovery project in arthropods, we used unbiased high-throughput sequencing to examine viromes of ticks coll...

journal_title：Virology journal

authors： Tokarz R,Sameroff S,Leon MS,Jain K,Lipkin WI

更新日期：2014-02-11 00:00:00

abstract：BACKGROUND:Infections with papillomaviruses induce type-specific immune responses, mainly directed against the major capsid protein, L1. Based on the propensity of the L1 protein to self-assemble into virus-like particles (VLPs), type-specific vaccines have already been developed. In order to generate vaccines that tar...

journal_title：Virology journal

authors： Roth SD,Sapp M,Streeck RE,Selinka HC

更新日期：2006-10-02 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV), human Rhinovirus (HRV) and human Metapneumo Virus (HMPV) are important viral pathogens causing acute respiratory tract infections in the hospitalized patients. Sensitive and accurate detection of RSV, HRV and HMPV is necessary for clinical diagnosis and treatment. RESULTS:...

journal_title：Virology journal

authors： Feng ZS,Zhao L,Wang J,Qiu FZ,Zhao MC,Wang L,Duan SX,Zhang RQ,Chen C,Qi JJ,Fan T,Li GX,Ma XJ

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) Core protein regulates multiple signaling pathways and alters cellular genes expression responsible for HCV induced pathogenesis leading to hepatocellular carcinoma (HCC). Prevalence of HCV genotype 3a associated HCC is higher in Pakistan as compare to the rest of world; however the m...

journal_title：Virology journal

authors： Jahan S,Khaliq S,Siddiqi MH,Ijaz B,Ahmad W,Ashfaq UA,Hassan S

更新日期：2011-11-23 00:00:00

abstract：BACKGROUND:The membrane topology and molecular mechanisms for endoplasmic reticulum (ER) localization of classical swine fever virus (CSFV) non-structural 2 (NS2) protien is unclear. We attempted to elucidate the subcellular localization, and the molecular mechanisms responsible for the localization of this protein in ...

journal_title：Virology journal

authors： Guo KK,Tang QH,Zhang YM,Kang K,He L

更新日期：2011-05-18 00:00:00

abstract：AIM:To evaluate the efficacy and safety of Entecavir (ETV) plus adefovir (ADV) for chronic hepatitis B (CHB) patients after multiple nucleos(t)ide analogue (NAs) failure treatment. METHODS:Hepatitis B e antigen (HBeAg)-positive patients who had a suboptimal response or developed resistance to two or more previous NAs ...

journal_title：Virology journal

authors： Xu XH,Li GL,Qin Y,Li Q,He FQ,Li JY,Pan QR,Deng JY

更新日期：2013-05-25 00:00:00

abstract：BACKGROUND:Swine-origin virus infection spreading widely could cause significant economic loss to porcine industry. Novel antiviral agents need to be developed to control this situation. METHODS:In this study, we evaluated the activities of five broad-spectrum antimicrobial peptides (AMPs) against several important sw...

journal_title：Virology journal

authors： Hu H,Guo N,Chen S,Guo X,Liu X,Ye S,Chai Q,Wang Y,Liu B,He Q

更新日期：2019-07-31 00:00:00

abstract：BACKGROUND:Varicella-zoster virus (VZV) causes chickenpox in children and shingles in older people. Currently, live attenuated vaccines based on the Oka strain are available worldwide. In Korea, an attenuated VZV vaccine has been developed from a Korean isolate and has been commercially available since 1994. Despite th...

journal_title：Virology journal

authors： Kim JI,Jung GS,Kim YY,Ji GY,Kim HS,Wang WD,Park HS,Park SY,Kim GH,Kwon SN,Lee KM,Ahn JH,Yoon Y,Lee CH

更新日期：2011-12-16 00:00:00

abstract：BACKGROUND:Endometrial cancer (EC) is one of the most common gynecological malignancies globally. Although progress has been made in surgical and other adjuvant therapies, there is still a great need to develop new approaches to further reduce the incidence and mortality of EC. Oncolytic virotherapy offers a novel prom...

journal_title：Virology journal

authors： Lin Y,Wang W,Wan J,Yang Y,Fu W,Pan D,Cai L,Cheng T,Huang X,Wang Y

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:In China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population. METHODS:The data were retrospectively extracted from the hospital medical charts of five centers...

journal_title：Virology journal

authors： Gu J,Yu G,Zhang X,Zhang S,Cai H,Ye C,Yang Y,Li D,Tong Z,Shen H,Chen H,Ding F,Lai X,Liu J,Xu M,Wu W

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are two of the most frequent respiratory pathogens that circulate worldwide. Infection with either virus can lead to hospitalization of young children, immunocompromised people and the elderly.A better understanding of the epidemiologi...

journal_title：Virology journal

authors： Sastre P,Ruiz T,Schildgen O,Schildgen V,Vela C,Rueda P

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:PHYVV and PepGMV are plant viruses reported in Mexico and Southern US as causal agents of an important pepper disease known as "rizado amarillo". Mixed infections with PHYVV and PepGMV have been reported in several hosts over a wide geographic area. Previous work suggested that these viruses might interact a...

journal_title：Virology journal

authors： Rentería-Canett I,Xoconostle-Cázares B,Ruiz-Medrano R,Rivera-Bustamante RF

更新日期：2011-03-08 00:00:00

abstract：:Members of the genus Cypovirus (family Reoviridae) are common pathogens of insects. These viruses have linear dsRNA genomes divided into 10-11 segments, which have generally been assumed to be monocistronic. Here, bioinformatic evidence is presented for a short overlapping coding sequence (CDS) in the cypovirus genome...

journal_title：Virology journal

authors： Firth AE,Atkins JF

更新日期：2008-05-20 00:00:00