Cross-sectional retrospective analysis of clinical characteristics of chronic hepatitis B patients with oral antiviral treatment in eastern China.

abstract：BACKGROUND:Porcine circovirus type-2b (PCV2b) is recognized as the etiological agent of the various clinical manifestations of porcine circovirus-associated disease (PCVAD). Previous studies have demonstrated effectiveness of chimeric PCV1-2 vaccines against PCV2b challenge. In this study, the efficacy of inactivated a...

journal_title：Virology journal

authors： Li J,Yu T,Wang X,Zhou J,Gao R,Zhang F,Gao X,Gao S,Liu X

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha interferon and ribavirin combined therapy for 24-48 weeks. One of the predictor of sustained virological response is an early virological response to treatment characterized as rapid respon...

journal_title：Virology journal

authors： Akram M,Idrees M,Hussain A,Afzal S,Ilyas M,Zafar S,Aftab M,Badar S,Khubaib B

更新日期：2011-05-23 00:00:00

abstract：BACKGROUND:Longitudinal mark-recapture studies of rodents in two sites in the Mbaracayú Biosphere Reserve in the Interior Atlantic Forest of eastern Paraguay have revealed a complex and intriguing pattern of hantaviruses harbored by rodents in this area. Full-length sequencing and phylogenetic analyses were conducted f...

journal_title：Virology journal

authors： Chu YK,Owen RD,Jonsson CB

更新日期：2011-08-12 00:00:00

abstract：BACKGROUND:Genome-wide RNAi screening has been widely used to identify host proteins involved in replication and infection of different viruses, and numerous host factors are implicated in the replication cycles of these viruses, demonstrating the power of this approach. However, discrepancies on target identification ...

journal_title：Virology journal

authors： Cheng H,Koning K,O'Hearn A,Wang M,Rumschlag-Booms E,Varhegyi E,Rong L

更新日期：2015-11-24 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide. There is no effective vaccine for prevention of HCV infection; however, a number of drugs are available for the treatment of infection. The availability of d...

journal_title：Virology journal

authors： Jardim ACG,Shimizu JF,Rahal P,Harris M

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Human cytomegalovirus UL114 encodes a uracil-DNA glycosylase homolog that is highly conserved in all characterized herpesviruses that infect mammals. Previous studies demonstrated that the deletion of this nonessential gene delays significantly the onset of viral DNA synthesis and results in a prolonged repl...

journal_title：Virology journal

authors： Prichard MN,Lawlor H,Duke GM,Mo C,Wang Z,Dixon M,Kemble G,Kern ER

更新日期：2005-07-15 00:00:00

abstract：:On 11 March 2020, the World Health Organization (WHO) announced Corona Virus Disease (COVID-19), a disease caused by a pathogen called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pandemic. This ongoing pandemic has now been reported in 215 countries with more than 23 million confirmed cases and mor...

journal_title：Virology journal

authors： Kiros M,Andualem H,Kiros T,Hailemichael W,Getu S,Geteneh A,Alemu D,Abegaz WE

更新日期：2020-10-02 00:00:00

abstract：:Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial and complete structures of nine out of twenty tail structural p...

journal_title：Virology journal

authors： Leiman PG,Arisaka F,van Raaij MJ,Kostyuchenko VA,Aksyuk AA,Kanamaru S,Rossmann MG

更新日期：2010-12-03 00:00:00

abstract：:Intracellular influenza virus nucleoprotein (NP) is characterized by a high efficiency of homo-polymers formation, however their antigenic structure is still incompletely known. Herein, we report that RNase-resistant intracellular NP homo-polymers have a highly ordered conformational antigenic epitope, which depends o...

journal_title：Virology journal

authors： Prokudina EN,Semenova N,Chumakov V,Stitz L

更新日期：2008-02-29 00:00:00

abstract：BACKGROUND:Astroviruses (AstVs) have been reported to infect and cause gastroenteritis in most animal species. Human AstVs were regarded the causative agent of viral diarrhea in children. In dogs, little is known about the epidemiology and clinical significance of AstV infection. FINDINGS:In this study, we collected a...

journal_title：Virology journal

authors： Zhou H,Liu L,Li R,Qin Y,Fang Q,Balasubramaniam VR,Wang G,Wei Z,Ouyang K,Huang W,Chen Y

更新日期：2017-08-17 00:00:00

abstract：BACKGROUND:Cotton blue disease (CBD), an important global cotton crop pathology responsible for major economic losses, is prevalent in the major cotton-producing states of Brazil. Typical CBD symptoms include stunting due to internodal shortening, leaf rolling, intense green foliage, and yellowing veins. Atypical CBD s...

journal_title：Virology journal

authors： Silva TF,Corrêa RL,Castilho Y,Silvie P,Bélot JL,Vaslin MF

更新日期：2008-10-20 00:00:00

abstract：:The most common etiologic agents causing chronic hepatitis are hepatitis C and B viruses (HCV and HBV, respectively). Chronic infection caused by HCV is considered one of the major causative agents of liver cirrhosis and hepatocellular carcinoma worldwide. In combination with the increasing rate of new HCV infections,...

journal_title：Virology journal

authors： Hoffmann TW,Duverlie G,Bengrine A

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Double-stranded RNA (dsRNA) and its mimic, polyinosinic acid: polycytidylic acid [Poly (I:C)], are recognized by toll-like receptor 3 (TLR3) and induce interferon (IFN)-β in many cell types. Poly (I:C) is the most potent IFN inducer. In in vivo mouse studies, intraperitoneal injection of Poly (I:C) elicited ...

journal_title：Virology journal

authors： Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-Nuegoonpipat A,Pan Y,Kameoka M,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

更新日期：2012-06-14 00:00:00

abstract：BACKGROUND:The broad enforcement of active surveillance for bovine spongiform encephalopathy (BSE) in 2000 led to the discovery of previously unnoticed, atypical BSE phenotypes in aged cattle that differed from classical BSE (C-type) in biochemical properties of the pathological prion protein. Depending on the molecula...

journal_title：Virology journal

authors： Tester S,Juillerat V,Doherr MG,Haase B,Polak M,Ehrensperger F,Leeb T,Zurbriggen A,Seuberlich T

更新日期：2009-05-26 00:00:00

abstract：BACKGROUND:RNA viruses are characterized by high rate of mutations mainly due to the lack of proofreading repair activities associated with its RNA-dependent RNA-polymerase (RdRp). In case of arboviruses, this phenomenon has lead to the existence of mixed population of genomic variants within the host called quasi-spec...

journal_title：Virology journal

authors： Jain J,Mathur K,Shrinet J,Bhatnagar RK,Sunil S

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:Human adenoviruses (Ads) have substantial potential for clinical applications in cancer patients. Conditionally replicating adenoviruses (CRAds) include oncolytic adenoviruses in which expression of the immediate early viral transactivator protein E1A is controlled by a cancer cell-selective promoter. To enh...

journal_title：Virology journal

authors： Fontecedro AC,Lutschg V,Eichhoff O,Dummer R,Greber UF,Hemmi S

更新日期：2010-07-29 00:00:00

abstract：BACKGROUND:A vaccine against all four dengue virus (DENV) serotypes includes the formulation of one genotype of each serotype. Although genetic similarities among genotypes within a serotype are higher as compared to those among serotypes, differences in the immunogenicity of the included genotypes would be a critical ...

journal_title：Virology journal

authors： Azami NAM,Moi ML,Ami Y,Suzaki Y,Lim CK,Taniguchi S,Saijo M,Takasaki T,Kurane I

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:PCR-based detection and identification of viruses assumes a known, relatively stable genome. Unfortunately, high mutation rates may lead to extensive changes in viral nucleic acid sequences making dedicated PCR primer use problematic. Furthermore, in bioterrorism, viral consensus sequences can be genetically...

journal_title：Virology journal

authors： Clem AL,Sims J,Telang S,Eaton JW,Chesney J

更新日期：2007-06-28 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) can be classified into nine genotypes (A-I) defined by sequence divergence of more than 8% based on the complete genome. This study aims to identify the genotypic distribution of HBV in 40 HBsAg-positive patients from Rondônia, Brazil. A fragment of 1306 bp partially comprising surfac...

journal_title：Virology journal

authors： Santos AO,Alvarado-Mora MV,Botelho L,Vieira DS,Pinho JR,Carrilho FJ,Honda ER,Salcedo JM

更新日期：2010-11-12 00:00:00

abstract：BACKGROUND:Progressive multifocal leukoencephalopathy (PML) onset, caused by Polyomavirus JC (JCPyV) in patients affected by immune-mediated diseases during biological treatment, raised concerns about the safety profile of these agents. Therefore, the aims of this study were the JCPyV reactivation monitoring and the no...

journal_title：Virology journal

authors： Bellizzi A,Anzivino E,Rodio DM,Cioccolo S,Scrivo R,Morreale M,Pontecorvo S,Ferrari F,Di Nardo G,Nencioni L,Carluccio S,Valesini G,Francia A,Cucchiara S,Palamara AT,Pietropaolo V

更新日期：2013-09-30 00:00:00

abstract：:Phage vB_EcoM_CBA120 (CBA120), isolated against Escherichia coli O157:H7 from a cattle feedlot, is morphologically very similar to the classic phage ViI of Salmonella enterica serovar Typhi. Until recently, little was known genetically or physiologically about the ViI-like phages, and none targeting E. coli have been ...

journal_title：Virology journal

authors： Kutter EM,Skutt-Kakaria K,Blasdel B,El-Shibiny A,Castano A,Bryan D,Kropinski AM,Villegas A,Ackermann HW,Toribio AL,Pickard D,Anany H,Callaway T,Brabban AD

更新日期：2011-09-07 00:00:00

abstract：BACKGROUND:Human herpes virus 8 (HHV-8) is the etiologic agent associated with development of classical, AIDS-related, iatrogenic, and endemic Kaposi's sarcoma (KS). Several studies provide strong evidence that HHV-8 can be transmitted by blood transfusion. We evaluated the seroprevalence and potential risk factors of ...

journal_title：Virology journal

authors： Wang X,He B,Zhang Z,Liu T,Wang H,Li X,Zhang Q,Lan K,Lu X,Wen H

更新日期：2010-03-17 00:00:00

abstract：BACKGROUND:Construction of conditionally-replicative Adenovirus (CRAd) is complex and time-consuming. While homologous recombination (HR) using a two-plasmid system in bacteria is commonly used to generate CRAds, alternative methods may be required when HR fails. Previously, in vitro ligation has been suggested to faci...

journal_title：Virology journal

authors： Haviv YS

更新日期：2009-02-07 00:00:00

abstract：:Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most important emerging diseases that have no available treatment to date. In recent yea...

journal_title：Virology journal

authors： García LL,Padilla L,Castaño JC

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) congenital infection is the major viral cause of well-documented birth defects in human. Because CMV is species-specific, the main obstacle to developing animal models for congenital infection is the difference in placental architecture, which preludes virus transmission across the plac...

journal_title：Virology journal

authors： Loh HS,Mohd-Lila MA,Abdul-Rahman SO,Kiew LJ

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (UL) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, we constructed a deletion mutant of ORF58 (pOka-BACDelta58) from the Oka parental genome cloned i...

journal_title：Virology journal

authors： Yoshii H,Sadaoka K,Matsuura M,Nagaike K,Takahashi M,Yamanishi K,Mori Y

更新日期：2008-04-30 00:00:00

abstract：:This study describes the prevalence of culture-positive adenovirus serotypes in culture-positive respiratory specimens sent to the Central Public Health Laboratory, Toronto, Ontario, Canada for the period September 2007-June 2008. Total nucleic acid was extracted from virus cultures using an automated extraction metho...

journal_title：Virology journal

authors： Yeung R,Eshaghi A,Lombos E,Blair J,Mazzulli T,Burton L,Drews SJ

更新日期：2009-01-26 00:00:00

abstract：BACKGROUND:LIN28B is involved in multiple cellular developmental processes, tissue inflammatory response and tumourigenesis. The association of LIN28B polymorphisms with hepatitis B virus (HBV) infection remains unknown. METHODS:This study investigated the association of LIN28B rs314277, rs314280, rs369065 and rs77599...

journal_title：Virology journal

authors： Han Q,Sang J,Fan X,Wang X,Zeng L,Zhang X,Zhang K,Li N,Lv Y,Liu Z

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:Otitis media (OM) affects ≥80% of children before the age of three. OM can arise following co-infection with influenza A virus (IAV) and the bacterium Streptococcus pneumoniae. We have previously shown that H3 IAV strains (such as Udorn/72) induced a higher rate of bacterial OM than H1 strains (such as PR8/3...

journal_title：Virology journal

authors： Short KR,Habets MN,Payne J,Reading PC,Diavatopoulos DA,Wijburg OL

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:Human caliciviruses (HuCV) are emerging enteric pathogens that are a common cause of diarrhea in humans worldwide. Due to the paucity of information on the molecular characterization of HuCV circulating in Mexico, the aim of this work was to investigate the diversity and molecular epidemiology of the HuCV in...

journal_title：Virology journal

authors： Gómez-Santiago F,Ribas-Aparicio RM,García-Lozano H

更新日期：2012-02-23 00:00:00