First genome sequences of Achromobacter phages reveal new members of the N4 family.

abstract：:One coronavirus strain was isolated from brain tissues of ten piglets with evident clinical manifestations of vomiting, diarrhea and dyskinesia in Jilin province in China. Antigenic and genomic characterizations of the virus (isolate PHEV-JLsp09) were based on multiplex PCR and negative staining electron microscopy an...

journal_title：Virology journal

authors： Gao W,Zhao K,Zhao C,Du C,Ren W,Song D,Lu H,Chen K,Li Z,Lan Y,Xie S,He W,Gao F

更新日期：2011-03-21 00:00:00

abstract：BACKGROUND:Infections with papillomaviruses induce type-specific immune responses, mainly directed against the major capsid protein, L1. Based on the propensity of the L1 protein to self-assemble into virus-like particles (VLPs), type-specific vaccines have already been developed. In order to generate vaccines that tar...

journal_title：Virology journal

authors： Roth SD,Sapp M,Streeck RE,Selinka HC

更新日期：2006-10-02 00:00:00

abstract：BACKGROUND:The diseases caused by Rice black streaked dwarf virus (RBSDV) and Southern rice black streaked dwarf virus (SRBSDV) have been occurring epidemically in China and southeastern Asia in recent years. A sensitive, reliable and quantitative method is required to detect and distinguish for RBSDV and SRBSDV in ric...

journal_title：Virology journal

authors： Zhang P,Mar TT,Liu W,Li L,Wang X

更新日期：2013-01-18 00:00:00

abstract：BACKGROUND:Avian hepatitis E virus (aHEV) has been associated with hepatitis-splenomegaly syndrome (HSS) in chickens along with asymptomatic subclinical infection in many cases. So far, four genotypes have been described, which cause infection in chickens, specifically in broiler breeders and layer chickens. In the pre...

journal_title：Virology journal

authors： Iqbal T,Rashid U,Idrees M,Afroz A,Kamili S,Purdy MA

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:Human T-cell Leukemia Virus type 1 (HTLV-1) is the etiological agent of tropical spastic paraparesis/HTLV-associated myelopathy (HAM/TSP) that can be identified in around 0.25%-3.8% of the infected population. Disease progression can be monitored by the proviral load and may depend on genetic factors, howeve...

journal_title：Virology journal

authors： Mota-Miranda AC,Barreto FK,Amarante MF,Batista E,Monteiro-Cunha JP,Farre L,Galvão-Castro B,Alcantara LC

更新日期：2013-03-06 00:00:00

abstract：BACKGROUND:Cotton blue disease (CBD), an important global cotton crop pathology responsible for major economic losses, is prevalent in the major cotton-producing states of Brazil. Typical CBD symptoms include stunting due to internodal shortening, leaf rolling, intense green foliage, and yellowing veins. Atypical CBD s...

journal_title：Virology journal

authors： Silva TF,Corrêa RL,Castilho Y,Silvie P,Bélot JL,Vaslin MF

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Dengue has emerged as the most significant of arboviral diseases in the 21st century. It is endemic to >100 tropical and sub-tropical countries around the world placing an estimated 3.6 billion people at risk. It is caused by four genetically similar but antigenically distinct, serotypes of dengue viruses. T...

journal_title：Virology journal

authors： Raut R,Beesetti H,Tyagi P,Khanna I,Jain SK,Jeankumar VU,Yogeeswari P,Sriram D,Swaminathan S

更新日期：2015-02-08 00:00:00

abstract：BACKGROUND:HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggested that both host and ...

journal_title：Virology journal

authors： Yamasaki LH,Arcuri HA,Jardim AC,Bittar C,de Carvalho-Mello IM,Rahal P

更新日期：2012-01-12 00:00:00

abstract：BACKGROUND:H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population. Vaccination is the best strategy to control H5N1 HPAIV infection in poultry and transmission to human population. The aim of this study is to identif...

journal_title：Virology journal

authors： Zhang W,Tu J,Zhao Z,Chen H,Jin M

更新日期：2012-05-23 00:00:00

abstract：BACKGROUND:Fast, reliable and easy to handle methods are required to facilitate urgently needed point-of-care testing (POCT) in the current coronavirus pandemic. Life-threatening severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread all over the world, infecting more than 33,500,000 people and...

journal_title：Virology journal

authors： Mautner L,Baillie CK,Herold HM,Volkwein W,Guertler P,Eberle U,Ackermann N,Sing A,Pavlovic M,Goerlich O,Busch U,Wassill L,Huber I,Baiker A

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Echovirus 6 (E6) infections are associated with aseptic meningitis and acute flaccid paralysis (AFP). But some infections, sometimes most of them, are asymptomatic. The mechanism of E6 virulence is unknown. Analyses of the molecular evolution of asymptomatic E6 may help understand why the infections show dif...

journal_title：Virology journal

authors： Sun H,Huang X,Lin K,Huang K,Chu J,Yang Z,Ma S

更新日期：2017-07-25 00:00:00

abstract：:RNA recombination is one of the two major factors that create RNA genome variability. Assessing its incidence in plant RNA viruses helps understand the formation of new isolates and evaluate the effectiveness of crop protection strategies. To search for recombination in Soybean mosaic virus (SMV), the causal agent of ...

journal_title：Virology journal

authors： Gagarinova AG,Babu M,Strömvik MV,Wang A

更新日期：2008-11-26 00:00:00

abstract：:The TAR RNA of HIV was engineered as an siRNA delivery vehicle to develop a combinatorial therapeutic approach. The TAR backbone was found to be a versatile backbone for expressing siRNAs. Upon expression in human cells, pronounced and specific inhibition of reporter gene expression was observed with TARmiR. The resul...

journal_title：Virology journal

authors： Unwalla HJ,Rossi JJ

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:To assess the potential effects of telbivudine (LdT) and entecavir (ETV) on renal function in patients with chronic hepatitis B (CHB), we performed a meta-analysis of the relevant data available on these agents to evaluate their effects on the estimated glomerular filtration rate (eGFR) during treatment. ME...

journal_title：Virology journal

authors： Wu X,Cai S,Li Z,Zheng C,Xue X,Zeng J,Peng J

更新日期：2016-04-09 00:00:00

abstract：BACKGROUND:Jamestown Canyon virus (JCV), family Bunyaviridae, is a mosquito-borne pathogen endemic in the United States and Canada that can cause encephalitis in humans and is considered an emerging threat to public health. The virus is genetically similar to Inkoo virus circulating in Europe, suggesting that much of t...

journal_title：Virology journal

authors： Bennett RS,Nelson JT,Gresko AK,Murphy BR,Whitehead SS

更新日期：2011-03-24 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV), human Rhinovirus (HRV) and human Metapneumo Virus (HMPV) are important viral pathogens causing acute respiratory tract infections in the hospitalized patients. Sensitive and accurate detection of RSV, HRV and HMPV is necessary for clinical diagnosis and treatment. RESULTS:...

journal_title：Virology journal

authors： Feng ZS,Zhao L,Wang J,Qiu FZ,Zhao MC,Wang L,Duan SX,Zhang RQ,Chen C,Qi JJ,Fan T,Li GX,Ma XJ

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. METHODS:The safety of LSDV was tested at doses of 104 and 106 plaque forming units in two strains of i...

journal_title：Virology journal

authors： Shen YJ,Shephard E,Douglass N,Johnston N,Adams C,Williamson C,Williamson AL

更新日期：2011-05-30 00:00:00

abstract：BACKGROUND:In adenoviruses, primary host cell recognition is generally performed by the head domains of their homo-trimeric fibre proteins. This first interaction is reversible. A secondary, irreversible interaction subsequently takes place via other adenovirus capsid proteins and leads to a productive infection. Altho...

journal_title：Virology journal

authors： Nguyen TH,Vidovszky MZ,Ballmann MZ,Sanz-Gaitero M,Singh AK,Harrach B,Benkő M,van Raaij MJ

更新日期：2015-05-22 00:00:00

abstract：BACKGROUND:Saffold Virus (SAFV) is a human cardiovirus that is suspected of causing infection of the central nervous system (CNS) in children. While recent animal studies have started to elucidate the pathogenesis of SAFV, very little is known about the mechanisms behind it. METHOD:In this study, we attempted to eluci...

journal_title：Virology journal

authors： Tan SZ,Prabakaran M

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Due to the high prevalence of viral infections having no specific treatment and the constant appearance of resistant viral strains, the development of novel antiviral agents is essential. The aim of this study was to evaluate the antiviral activity against bovine viral diarrhea virus, herpes simplex virus ty...

journal_title：Virology journal

authors： Visintini Jaime MF,Redko F,Muschietti LV,Campos RH,Martino VS,Cavallaro LV

更新日期：2013-07-27 00:00:00

abstract：BACKGROUND:With the clinical development of several antiviral intervention strategies for influenza, it becomes crucial to explore viral load shedding in the nasal cavity as a biomarker for treatment success, but also to explore sampling strategies for sensible and reliable virus collection. FINDINGS:In this study, 24...

journal_title：Virology journal

authors： Van Wesenbeeck L,Meeuws H,D'Haese D,Ispas G,Houspie L,Van Ranst M,Stuyver LJ

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:The human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein. Though mutants lacking agnoprotein are severely reduced in producing infectious virions, the exact function of this peptide remains incompletely understood. To elucidate the function of agnoprotein, we searched for novel ...

journal_title：Virology journal

authors： Gerits N,Johannessen M,Tümmler C,Walquist M,Kostenko S,Snapkov I,van Loon B,Ferrari E,Hübscher U,Moens U

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The pattern recognition receptors (PPRs) are the earliest phase of the host defense against pathogens in genital epithelium, and toll-like receptors (TLRs) are best characterized PPRs mediating innate immune responses. Herpes simplex virus type 2 (HSV-2), a member of herpesviridae family, causes one of the m...

journal_title：Virology journal

authors： Lv X,Wang H,Su A,Xu S,Chu Y

更新日期：2018-11-12 00:00:00

abstract：BACKGROUND:The influenza virus is still one of the most important respiratory risks affecting humans which require effective treatments. In this case, traditional medications are of interest. HESA-A is an active natural biological compound from herbal-marine origin. Previous studies have reported that the therapeutic p...

journal_title：Virology journal

authors： Mehrbod P,Ideris A,Omar AR,Hair-Bejo M,Tan SW,Kheiri MT,Tabatabaian M

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:Persistent infection of human papillomavirus (HPV) types 16 and 18 causes cervical cancer. To better understand immune responses to the prophylactic vaccine, HPV 16/18 L1 virus-like particles (HPV-VLPs), we investigated B cell epitopes of HPV16 L1-derived peptides. METHODS:Sera from mice immunized with HPV-...

journal_title：Virology journal

authors： Fukui A,Matsueda S,Kawano K,Tsuda N,Komatsu N,Shichijo S,Sasada T,Hattori S,Ushijima K,Itoh K,Kamura T

更新日期：2012-09-14 00:00:00

abstract：:Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated t...

journal_title：Virology journal

authors： Adlhoch C,Kaiser M,Ellerbrok H,Pauli G

更新日期：2010-07-25 00:00:00

abstract：BACKGROUND:The recently sequenced 218 kb genome of morphologically atypical Bacillus thuringiensis phage 0305phi8-36 exhibited only limited detectable homology to known bacteriophages. The only known relative of this phage is a string of phage-like genes called BtI1 in the chromosome of B. thuringiensis israelensis. Th...

journal_title：Virology journal

authors： Hardies SC,Thomas JA,Serwer P

更新日期：2007-10-05 00:00:00

abstract：BACKGROUND:The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain. RESULTS:We have addressed this issue in ...

journal_title：Virology journal

authors： Garg H,Joshi A,Ye C,Shankar P,Manjunath N

更新日期：2011-01-21 00:00:00

abstract：BACKGROUND:Integrase (IN) is an essential protein for HIV replication that catalyzes insertion of the reverse-transcribed viral genome into the host chromosome during the early steps of viral infection. Highly active anti-retroviral therapy is a HIV/AIDS treatment method that combines three or more antiviral drugs ofte...

journal_title：Virology journal

authors： Park KH,Kim M,Bae SE,Lee HJ,Kim KC,Choi BS,Kim YB

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Human caliciviruses (HuCV) are emerging enteric pathogens that are a common cause of diarrhea in humans worldwide. Due to the paucity of information on the molecular characterization of HuCV circulating in Mexico, the aim of this work was to investigate the diversity and molecular epidemiology of the HuCV in...

journal_title：Virology journal

authors： Gómez-Santiago F,Ribas-Aparicio RM,García-Lozano H

更新日期：2012-02-23 00:00:00