Molecular evolution of two asymptomatic echovirus 6 strains that constitute a novel branch of recently epidemic echovirus 6 in China.

abstract：BACKGROUND:Mumps virus is a negative-sense, single stranded RNA virus consisting of a ribonucleocapsid core enveloped by a lipid membrane derived from host cell, which causes mumps disease preventable by vaccination. Since virus lipid envelope and glycosylation pattern are not encoded by the virus but dependent on the ...

journal_title：Virology journal

authors： Brgles M,Bonta M,Šantak M,Jagušić M,Forčić D,Halassy B,Allmaier G,Marchetti-Deschmann M

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:Varicella (chickenpox) exhibits a characteristic epidemiological pattern which is associated with climate. In general, primary infections in tropical regions are comparatively less frequent among children than in temperate regions. This peculiarity regarding varicella-zoster virus (VZV) infection among certa...

journal_title：Virology journal

authors： Vaughan G,Rodríguez-Castillo A,Cruz-Rivera MY,Ruiz-Tovar K,Ramírez-González JE,Rivera-Osorio P,Fonseca-Coronado S,Carpio-Pedroza JC,Cazares F,Vazquez-Pichardo M,Anaya L,Escobar-Gutiérrez A

更新日期：2011-07-27 00:00:00

abstract：BACKGROUND:Since its emergence in March 2009, the pandemic 2009 H1N1 influenza A virus has posed a serious threat to public health. To trace the evolutionary path of these new pathogens, we performed a selection-pressure analysis of a large number of hemagglutinin (HA) and neuraminidase (NA) gene sequences of H1N1 infl...

journal_title：Virology journal

authors： Li W,Shi W,Qiao H,Ho SY,Luo A,Zhang Y,Zhu C

更新日期：2011-04-21 00:00:00

abstract：BACKGROUND:Farmington virus (FARV) is a rhabdovirus that was isolated from a wild bird during an outbreak of epizootic eastern equine encephalitis on a pheasant farm in Connecticut, USA. FINDINGS:Analysis of the nearly complete genome sequence of the prototype CT AN 114 strain indicates that it encodes the five canoni...

journal_title：Virology journal

authors： Palacios G,Forrester NL,Savji N,Travassos da Rosa AP,Guzman H,Detoy K,Popov VL,Walker PJ,Lipkin WI,Vasilakis N,Tesh RB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Entry of Ebolavirus to the target cells is mediated by the viral glycoprotein GP. The native GP exists as a homotrimer on the virions and contains two subunits, a surface subunit (GP1) that is involved in receptor binding and a transmembrane subunit (GP2) that mediates the virus-host membrane fusion. Previou...

journal_title：Virology journal

authors： Manicassamy B,Rong L

更新日期：2009-06-08 00:00:00

abstract：BACKGROUND:Newcastle disease (ND), caused by Newcastle disease virus (NDV), is a highly contagious disease of birds and has been one of the major causes of economic losses in the poultry industry. Despite routine vaccination programs, sporadic cases have occasionally occurred in the country and remain a constant threat...

journal_title：Virology journal

authors： Berhanu A,Ideris A,Omar AR,Bejo MH

更新日期：2010-08-08 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne virus that has four serotypes. Collection of serum from patients is time- and labor- consuming, and presents a high injury risk for infants and children. The genomic and serological diagnosis of imported dengue fever from a urine sample was used as a non-invasive diagnostic meth...

journal_title：Virology journal

authors： Ma X,Zhen W,Yang P,Sun X,Nie W,Zhang L,Xu H,Hu K

更新日期：2014-03-25 00:00:00

abstract：BACKGROUND:Co-infection of multiple genotypes of human papillomavirus (HPV) is commonly observed among women with abnormal cervical cytology, but how different HPVs interact with each other in the same cell is not clearly understood. A previous study using cultured keratinocytes revealed that genome replication of one ...

journal_title：Virology journal

authors： Mori S,Kusumoto-Matsuo R,Ishii Y,Takeuchi T,Kukimoto I

更新日期：2014-01-24 00:00:00

abstract：BACKGROUND:Human herpesviruses have been hypothesized as environmental triggers in the development of autoimmune thyroid diseases (AITD), and in particular active human herpesvirus 6A (HHV-6A) infection was detected in thyrocytes of Hashimoto's thyroiditis (HT) patients, who also show specific anti-viral immune respons...

journal_title：Virology journal

authors： Caselli E,D'Accolti M,Soffritti I,Zatelli MC,Rossi R,Degli Uberti E,Di Luca D

更新日期：2017-01-11 00:00:00

abstract：:The prevalence of North American orthopoxviruses in nature is unknown and may be more difficult to ascertain due to wide spread use of vaccinia virus recombinant vaccines in the wild. A real time PCR assay was developed to allow for highly sensitive and specific detection of North American orthopoxvirus DNA in animal ...

journal_title：Virology journal

authors： Gallardo-Romero NF,Velasco-Villa A,Weiss SL,Emerson GL,Carroll DS,Hughes CM,Li Y,Karem KL,Damon IK,Olson VA

更新日期：2011-06-20 00:00:00

abstract：BACKGROUND:Saffold Virus (SAFV) is a human cardiovirus that is suspected of causing infection of the central nervous system (CNS) in children. While recent animal studies have started to elucidate the pathogenesis of SAFV, very little is known about the mechanisms behind it. METHOD:In this study, we attempted to eluci...

journal_title：Virology journal

authors： Tan SZ,Prabakaran M

更新日期：2016-11-25 00:00:00

abstract：:Hairpin RNAs have been used to confer resistance to viruses in plants through RNA silencing. However, it has not been demonstrated that RNA silencing was effective against inoculation by aphids of non-persistently transmitted viruses, the major route of plant virus spread in nature. As a proof-of-principle strategy, w...

journal_title：Virology journal

authors： Vargas M,Martínez-García B,Díaz-Ruíz JR,Tenllado F

更新日期：2008-03-19 00:00:00

abstract：BACKGROUND:Double-stranded RNA (dsRNA) and its mimic, polyinosinic acid: polycytidylic acid [Poly (I:C)], are recognized by toll-like receptor 3 (TLR3) and induce interferon (IFN)-β in many cell types. Poly (I:C) is the most potent IFN inducer. In in vivo mouse studies, intraperitoneal injection of Poly (I:C) elicited ...

journal_title：Virology journal

authors： Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-Nuegoonpipat A,Pan Y,Kameoka M,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

更新日期：2012-06-14 00:00:00

abstract：BACKGROUND:We have characterised a new highly divergent geminivirus species, Eragrostis curvula streak virus (ECSV), found infecting a hardy perennial South African wild grass. ECSV represents a new genus-level geminivirus lineage, and has a mixture of features normally associated with other specific geminivirus genera...

journal_title：Virology journal

authors： Varsani A,Shepherd DN,Dent K,Monjane AL,Rybicki EP,Martin DP

更新日期：2009-03-25 00:00:00

abstract：BACKGROUND:Nonstructural glycoprotein 4 (NSP4) encoded by rotavirus is the only viral protein currently believed to function as an enterotoxin. NSP4 is synthesized as an intracellular transmembrane glycoprotein and as such is essential for virus assembly. Infection of polarized Caco-2 cells with rotavirus also results ...

journal_title：Virology journal

authors： Didsbury A,Wang C,Verdon D,Sewell MA,McIntosh JD,Taylor JA

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Rabbit haemorrhagic disease virus (RHDV), as the pathogeny of Rabbit haemorrhagic disease, can cause a highly infectious and often fatal disease only affecting wild and domestic rabbits. Recent researches revealed that it, as one number of the Caliciviridae, has some specialties in its genome, its reproducti...

journal_title：Virology journal

authors： Tian XT,Li BY,Zhang L,Jiao WQ,Liu JX

更新日期：2011-11-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a zoonotic pathogen of which several species of animal were reported as reservoirs. Swine stands out as the major reservoir for HEV infection in humans, as suggested by the close genetic relationship of swine and human virus and cross-species infection of HEV. Up to now, the mechanism of cro...

journal_title：Virology journal

authors： Zhang W,Hua X,Shen Q,Yang S,Yin H,Cui L

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus. Previous studies have identified neutralizing antibodies from Zika patients that bind to quaternary epitopes across neighboring envelope (E) proteins, called E dimer epitopes (EDE). An asparagine-linked glycan on the "glycan loop...

journal_title：Virology journal

authors： Henderson EA,Tam CC,Cheng LW,Ngono AE,Nguyen AV,Shresta S,McGee M,Padgett H,Grill LK,Martchenko Shilman M

更新日期：2020-03-31 00:00:00

abstract：:Most viruses take advantage of endocytic pathways to gain entry into host cells and initiate infections. Understanding of virus entry via endocytosis is critically important for the design of antiviral strategies. Virus entry via endocytosis is a complex process involving hundreds of cellular proteins. The entire proc...

journal_title：Virology journal

authors： Barrow E,Nicola AV,Liu J

更新日期：2013-06-05 00:00:00

abstract：BACKGROUND:This study aimed at reseaching the immune effect of porcine circovirus type 2 (PCV2) DNA vaccine containing CpG motif on mice. METHODS:A total of 40 6-week-old female BALB/c mice were randomly divided into four groups which were immunized by 18CpG-pVAX1-ORF2, pVAX1-ORF2, pVAX1 and PBS, respectively, and imm...

journal_title：Virology journal

authors： Li J,Yu J,Xu S,Shi J,Xu S,Wu X,Fu F,Peng Z,Zhang L,Zheng S,Yuan X,Cong X,Sun W,Cheng K,Du Y,Wu J,Wang J

更新日期：2016-11-14 00:00:00

abstract：:The NanoSight LM10 with Nanoparticle tracking analysis (NTA) software was evaluated for the quantification of latex particles, adenovirus 5, and influenza virus. The inter-day variability was determined by measuring the same sample over several consecutive days and the method's accuracy was demonstrated by using known...

journal_title：Virology journal

authors： Kramberger P,Ciringer M,Štrancar A,Peterka M

更新日期：2012-11-12 00:00:00

abstract：BACKGROUND:Nuclear factor-kappaB (NF-κB) is an inducible transcription factor that plays a key role in inflammation and immune responses, as well as in the regulation of cell proliferation and survival. Previous studies by our group and others have demonstrated that porcine reproductive and respiratory syndrome virus (...

journal_title：Virology journal

authors： Fang Y,Fang L,Wang Y,Lei Y,Luo R,Wang D,Chen H,Xiao S

更新日期：2012-04-30 00:00:00

abstract：BACKGROUND:Classical swine fever (CSF) is a highly contagious fatal infectious disease caused by classical swine fever virus (CSFV). A better understanding of CSFV replication is important for the study of pathogenic mechanism of CSF. With the development of novel RNA in situ Hybridization method, quantitatively locali...

journal_title：Virology journal

authors： Zhang Q,Xu L,Zhang Y,Wang T,Zou X,Zhu Y,Zhao Y,Li C,Chen K,Sun Y,Sun J,Zhao Q,Wang Q

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND:H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China, a crucial stopover or wintering site for migratory wild birds along the East As...

journal_title：Virology journal

authors： Hu C,Li X,Zhu C,Zhou F,Tang W,Wu D,Li Z,Zhou L,Liu J,Wei X,Cui J,Wang T,He G

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:The plateau pika (Ochotona curzoniae) is a small rabbit-like mammal that lives at high altitudes in the Qinghai-Tibet plateau and is in close contact with birds. Following the outbreak of highly pathogenic avian influenza (HPAI) H5N1 during 2005 in the migratory birds of Qinghai Lake, two clades of H5N1 have...

journal_title：Virology journal

authors： Li Y,Xiao H,Huang C,Sun H,Li L,Su J,Ma J,Liu D,Wang H,Liu W,Gao GF,Li X,Yan J

更新日期：2015-04-14 00:00:00

abstract：:Presumptive phage particles associated with Xylella fastidiosa strain Temecula-1 grown in PW broth were observed by transmission electron microscopy (TEM) in ultrathin sections of bacterial cell-containing low speed centrifugation pellets and in partially purified preparations from CsCl equilibrium centrifugation dens...

journal_title：Virology journal

authors： Chen J,Civerolo EL

更新日期：2008-06-06 00:00:00

abstract：BACKGROUND:Bovine leukemia virus (BLV), which is closely related to human T-cell leukemia virus, is the etiological agent of enzootic bovine leukosis, a disease characterized by a highly prolonged course involving persistent lymphocytosis and B-cell lymphoma. The bovine major histocompatibility complex class II region ...

journal_title：Virology journal

authors： Bai L,Takeshima SN,Sato M,Davis WC,Wada S,Kohara J,Aida Y

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:Newcastle Disease (ND) is a highly contagious and economically devastating disease of poultry. At present, limited molecular epidemiological data are available regarding the causes of ND outbreaks in vaccinated commercial poultry farms. Knowing the genomic characteristics of Newcastle disease virus (NDV) inf...

journal_title：Virology journal

authors： Umali DV,Ito H,Suzuki T,Shirota K,Katoh H,Ito T

更新日期：2013-11-09 00:00:00

abstract：BACKGROUND:Host serine proteases are essential for the influenza virus life cycle because the viral haemagglutinin is synthesized as a precursor which requires proteolytic maturation. Therefore, we studied the activity and expression of serine proteases in lungs from mice infected with influenza and evaluated the effec...

journal_title：Virology journal

authors： Bahgat MM,Błazejewska P,Schughart K

更新日期：2011-01-20 00:00:00

abstract：BACKGROUND:Yearly influenza virus mutations potentially affect the performance of molecular assays, if nucleic acid changes involve the sequences in the assay. Because individual patient viral loads depend on variables such as duration of illness, specimen type, age, and immunosuppression, we examined seasonal populati...

journal_title：Virology journal

authors： Rand KH,Pieretti M,Arcenas R,Beal SG,Houck H,Boslet E,Lednicky JA

更新日期：2017-07-14 00:00:00