Morphological evidence for phages in Xylella fastidiosa.

abstract：BACKGROUND:Porcine circovirus type 2 (PCV2), the causative agent of postweaning multisystemic wasting syndrome (PMWS), is a serious economic problem in the swine industry. Different genotypes (PCV2a, PCV2b and PCV2d) of the virus are present in the clinical cases in China, and it is necessary to elucidate the pathogeni...

journal_title：Virology journal

authors： Guo LJ,Lu YH,Huang LP,Wei YW,Wu HL,Liu CM

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Influenza viruses are characterized by their highly variable surface proteins HA and NA. The third surface protein M2 is a nearly invariant protein in all Influenza A strains. Despite extensive studies in other animal models, this study is the first to describe the use of recombinant M2 protein and a peptide...

journal_title：Virology journal

authors： Swinkels WJ,Hoeboer J,Sikkema R,Vervelde L,Koets AD

更新日期：2013-06-24 00:00:00

abstract：BACKGROUND:Patchouli alcohol (PA) is a tricyclic sesquiterpene extracted from Pogostemonis Herba, which is a traditional Chinese medicine used for therapy of inflammatory diseases. Recent studies have shown that PA has various pharmacological activities, including anti-bacterial and anti-viral effects. METHODS:In this...

journal_title：Virology journal

authors： Yu Y,Zhang Y,Wang S,Liu W,Hao C,Wang W

更新日期：2019-12-23 00:00:00

abstract：BACKGROUND:Using a murine model of parainfluenza virus infection (mPIV1 or Sendai virus; SeV), we compared the inflammatory responses to lethal and sub-lethal infections in inbred DBA/2 mice. METHODS:Mice were intranasally inoculated with either 1.6×10(3) or 1.6×10(5) infectious units (IU) of SeV or diluent control. C...

journal_title：Virology journal

authors： Suryadevara M,Bonville CA,Rosenberg HF,Domachowske JB

更新日期：2013-12-21 00:00:00

abstract：BACKGROUND:Rotavirus (RV) is the main cause of severe gastroenteritis in children. An effective vaccination regime against RV can substantially reduce morbidity and mortality. Previous studies have demonstrated the efficacy of virus-like particles formed by RV VP2 and VP6 (VLP2/6), as well as that of recombinant adenov...

journal_title：Virology journal

authors： Zhou H,Guo L,Wang M,Qu J,Zhao Z,Wang J,Hung T

更新日期：2011-01-05 00:00:00

abstract：BACKGROUND:Influenza A virus infects not only humans, but also other species including avian and swine. If a novel influenza A subtype acquires the ability to spread between humans efficiently, it could cause the next pandemic. Therefore it is necessary to understand the evolutionary processes of influenza A viruses in...

journal_title：Virology journal

authors： Furuse Y,Suzuki A,Kamigaki T,Oshitani H

更新日期：2009-05-29 00:00:00

abstract：:Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear. Recently, some new progress were achieved in molecular character of MDV. Along with the genomic sequencing o...

journal_title：Virology journal

authors： Tian M,Zhao Y,Shi M,Lin Y,Zou N,Liu P,Wen X,Cao S,Huang Y

更新日期：2010-12-23 00:00:00

abstract：BACKGROUND:The UL54 protein of Duck Enteritis Virus (DEV) is a homolog of herpes simplex virus-1 (HSV-1) immediate-early infectious cell protein 27 (ICP27), a multifunctional protein essential for viral infection. Nonetheless, there is little information on the UL54 protein of DEV. METHODS:The UL54 gene was cloned int...

journal_title：Virology journal

authors： Liu C,Cheng A,Wang M,Chen S,Jia R,Zhu D,Liu M,Sun K,Yang Q,Chen X

更新日期：2015-11-25 00:00:00

abstract：:The Filoviridae family comprises of Ebola and Marburg viruses, which are known to cause lethal hemorrhagic fever. However, there is no effective anti-viral therapy or licensed vaccines currently available for these human pathogens. The envelope glycoprotein (GP) of Ebola virus, which mediates entry into target cells, ...

journal_title：Virology journal

authors： Bhattacharyya S,Hope TJ

更新日期：2011-01-12 00:00:00

abstract：BACKGROUND:HIV-1 is highly variable genetically and at protein level, a property it uses to subvert antiviral immunity and treatment. The aim of this study was to assess if HIV subtype differences were associated with variations in glycosylation patterns and co-receptor tropism among HAART patients experiencing differe...

journal_title：Virology journal

authors： Kitawi RC,Hunja CW,Aman R,Ogutu BR,Muigai AW,Kokwaro GO,Ochieng W

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:In China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population. METHODS:The data were retrospectively extracted from the hospital medical charts of five centers...

journal_title：Virology journal

authors： Gu J,Yu G,Zhang X,Zhang S,Cai H,Ye C,Yang Y,Li D,Tong Z,Shen H,Chen H,Ding F,Lai X,Liu J,Xu M,Wu W

更新日期：2021-01-13 00:00:00

abstract：:Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial and complete structures of nine out of twenty tail structural p...

journal_title：Virology journal

authors： Leiman PG,Arisaka F,van Raaij MJ,Kostyuchenko VA,Aksyuk AA,Kanamaru S,Rossmann MG

更新日期：2010-12-03 00:00:00

abstract：BACKGROUND:Some genotypes of human papillomaviruses can infect the genital tract and they are important infectious agents which their oncogenicity is regardable. Thus the aim of this study was to determine the prevalence of various genital human papillomaviruses (HPV) among women being subjected to routine pap smear te...

journal_title：Virology journal

authors： Zandi K,Eghbali SS,Hamkar R,Ahmadi S,Ramedani E,Deilami I,Nejad HA,Farshadpour F,Rastian Z

更新日期：2010-03-22 00:00:00

abstract：BACKGROUND:Andes virus (ANDV), a rodent-borne Hantavirus, is the major etiological agent of Hantavirus cardiopulmonary syndrome (HCPS) in South America, which is mainly characterized by a vascular leakage with high rate of fatal outcomes for infected patients. Currently, neither specific therapy nor vaccines are availa...

journal_title：Virology journal

authors： Marsac D,García S,Fournet A,Aguirre A,Pino K,Ferres M,Kalergis AM,Lopez-Lastra M,Veas F

更新日期：2011-05-13 00:00:00

abstract：BACKGROUND:Early in infection, the genome of the influenza A virus, consisting of eight complexes of RNA and proteins (termed viral ribonucleoproteins; vRNPs), enters the nucleus of infected cells for replication. Incoming vRNPs are imported into the nucleus of infected cells using at least two nuclear localization seq...

journal_title：Virology journal

authors： Wu WW,Panté N

更新日期：2009-06-02 00:00:00

abstract：BACKGROUND:Public health risks associated to infection by human coronaviruses remain considerable and vaccination is a key option for preventing the resurgence of severe acute respiratory syndrome coronavirus (SARS-CoV). We have previously reported that antibodies elicited by a SARS-CoV vaccine candidate based on recom...

journal_title：Virology journal

authors： Yip MS,Leung NH,Cheung CY,Li PH,Lee HH,Daëron M,Peiris JS,Bruzzone R,Jaume M

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Acute gastroenteritis caused by bacteria, virus and parasite is an important cause of childhood morbidity and mortality in developing countries. Rotavirus and norovirus have been recognized as the most common pathogens causing acute gastroenteritis among children. However, there is still no valuable data abo...

journal_title：Virology journal

authors： Sai L,Sun J,Shao L,Chen S,Liu H,Ma L

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:Mumps virus (MuV) is a highly infectious paramyxovirus closely related to measles virus (MeV). Despite the availability of a mumps vaccine, outbreaks continue to occur and no treatment options are available. Vitamin A and other naturally occurring retinoids inhibit the replication of MeV in vitro. METHODS:A...

journal_title：Virology journal

authors： Soye KJ,Trottier C,Di Lenardo TZ,Restori KH,Reichman L,Miller WH Jr,Ward BJ

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:An extensive outbreak of equine influenza occurred across multiple countries in South America during 2012. The epidemic was first reported in Chile then spread to Brazil, Uruguay and Argentina, where both vaccinated and unvaccinated animals were affected. In Brazil, infections were widespread within 3months ...

journal_title：Virology journal

authors： Alves Beuttemmüller E,Woodward A,Rash A,Dos Santos Ferraz LE,Fernandes Alfieri A,Alfieri AA,Elton D

更新日期：2016-03-19 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is the most common cause of intrauterine infections worldwide. The toll-like receptors (TLRs) have been reported as important factors in immune response against HCMV. Particularly, TLR2, TLR4 and TLR9 have been shown to be involved in antiviral immunity. Evaluation of the role of...

journal_title：Virology journal

authors： Wujcicka W,Paradowska E,Studzińska M,Wilczyński J,Nowakowska D

更新日期：2017-03-24 00:00:00

abstract：INTRODUCTION:Despite being a leading infectious cause of childhood disability globally, testing for cytomegalovirus (CMV) infections in pregnancy is generally not done in Sub-Sahara Africa (SSA), where breastfeeding practice is almost universal. Whilst CMV and human immunodeficiency virus (HIV) are both endemic in SSA,...

journal_title：Virology journal

authors： Duri K,Chimhuya S,Gomo E,Munjoma PT,Chandiwana P,Yindom LM,Mhandire K,Ziruma A,Mtapuri-Zinyowera S,Mazengera LR,Misselwitz B,Gumbo FZ,Jordi S,Rowland-Jones S,for (UZBCS) The U Z Birth Cohort Study Team.

更新日期：2021-01-29 00:00:00

abstract：BACKGROUND:Human pegivirus-1 (HPgV-1) is a member of the Flaviviridae family whose genomic organization and mode of cellular entry is similar to that of hepatitis C virus (HCV). The E2 glycoprotein of HPgV-1 is the principle mediator in the virus-cell interaction and as such harbors most of HPgV-1's antigenic determina...

journal_title：Virology journal

authors： Vitrenko Y,Kostenko I,Kulebyakina K,Sorochynska K

更新日期：2017-08-31 00:00:00

abstract：:The I5L gene is one of approximately 90 genes that are conserved throughout the chordopoxvirus family, and hence are presumed to play vital roles in the poxvirus life cycle. Previous work had indicated that the VP13 protein, a component of the virion membrane, was encoded by the I5L gene, but no additional studies had...

journal_title：Virology journal

authors： Unger B,Nichols RJ,Stanitsa ES,Traktman P

更新日期：2008-12-15 00:00:00

abstract：BACKGROUND:Data about molecular diversity of commonly circulating type A influenza viruses in Ontario swine are scarce. Yet, this information is essential for surveillance of animal and public health, vaccine updates, and for understanding virus evolution and its large-scale spread. METHODS:The study population consis...

journal_title：Virology journal

authors： Grgić H,Costa M,Friendship RM,Carman S,Nagy É,Wideman G,Weese S,Poljak Z

更新日期：2014-11-22 00:00:00

abstract：BACKGROUND:Classical swine fever (CSF) is a highly contagious fatal infectious disease caused by classical swine fever virus (CSFV). A better understanding of CSFV replication is important for the study of pathogenic mechanism of CSF. With the development of novel RNA in situ Hybridization method, quantitatively locali...

journal_title：Virology journal

authors： Zhang Q,Xu L,Zhang Y,Wang T,Zou X,Zhu Y,Zhao Y,Li C,Chen K,Sun Y,Sun J,Zhao Q,Wang Q

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND:Porcine sapovirus was first identified in the United States in 1980, hitherto, several Asian countries have detected this virus. In 2008, the first outbreak of gastroenteritis in piglets caused by porcine sapovirus in China was reported. The complete genome of the identified SaV strain Ch-sw-sav1 was sequenc...

journal_title：Virology journal

authors： Yang S,Zhang W,Shen Q,Huang F,Wang Y,Zhu J,Cui L,Yang Z,Hua X

更新日期：2009-12-06 00:00:00

abstract：BACKGROUND:Host serine proteases are essential for the influenza virus life cycle because the viral haemagglutinin is synthesized as a precursor which requires proteolytic maturation. Therefore, we studied the activity and expression of serine proteases in lungs from mice infected with influenza and evaluated the effec...

journal_title：Virology journal

authors： Bahgat MM,Błazejewska P,Schughart K

更新日期：2011-01-20 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus. Previous studies have identified neutralizing antibodies from Zika patients that bind to quaternary epitopes across neighboring envelope (E) proteins, called E dimer epitopes (EDE). An asparagine-linked glycan on the "glycan loop...

journal_title：Virology journal

authors： Henderson EA,Tam CC,Cheng LW,Ngono AE,Nguyen AV,Shresta S,McGee M,Padgett H,Grill LK,Martchenko Shilman M

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:Aleutian mink disease virus (AMDV) is the cause of a chronic immune complex disease, Aleutian disease (AD), which is common in mink-producing countries. In 2005, implementation of an AMDV eradication programme in Finland created a need for an automated high-throughput assay. The aim of this study was to vali...

journal_title：Virology journal

authors： Knuuttila A,Aronen P,Eerola M,Gardner IA,Virtala AM,Vapalahti O

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:The effect of antiviral therapy in chronic hepatitis B (CHB) on reducing the risk of long-term complications (LTCs) remains unclear so far. To study whether long-term nucleos(t)ide analogues therapy can reduce the risk of long-term complications. METHODS:We searched MEDLINE, EMBASE, OVID, the Cochrane Centr...

journal_title：Virology journal

authors： Zhang QQ,An X,Liu YH,Li SY,Zhong Q,Wang J,Hu HD,Zhang DZ,Ren H,Hu P

更新日期：2011-02-15 00:00:00