High prevalence of porcine Hokovirus in German wild boar populations.

abstract：BACKGROUND:Chronic viral hepatitis B remains a global public health concern. Currently, several drugs, such as lamivudine and telbivudine, are recommended for treatment of patients with chronic hepatitis B. However, there are no conclusive results on the comparison of the efficacy of lamivudine (LAM) and telbivudine (L...

journal_title：Virology journal

authors： Zhao S,Tang L,Fan X,Chen L,Zhou R,Dai X

更新日期：2010-09-03 00:00:00

abstract：BACKGROUND:The binding of viral-specific antibodies to cell-surface antigens usually results in down modulation of the antigen through redistribution of antigens into patches that subsequently may be internalized by endocytosis or may form caps that can be expelled to the extracellular space. Here, by use of confocal-l...

journal_title：Virology journal

authors： Sarmiento RE,Tirado RG,Valverde LE,Gómez-Garcia B

更新日期：2007-07-03 00:00:00

abstract：:Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear. Recently, some new progress were achieved in molecular character of MDV. Along with the genomic sequencing o...

journal_title：Virology journal

authors： Tian M,Zhao Y,Shi M,Lin Y,Zou N,Liu P,Wen X,Cao S,Huang Y

更新日期：2010-12-23 00:00:00

abstract：BACKGROUND:Pseudocowpox virus (PCPV) infects cattle worldwide with zoonotic potential but has not been isolated in Japan. Thus, the epidemiological status of PCPV infection in cattle is undetermined. RESULTS:In May 2016, a cattle in a farm in Yamaguchi Prefecture showed white vesicles and hyperemia in the mucosa under...

journal_title：Virology journal

authors： Ohtani A,Yokoyama A,Narushige H,Inoshima Y

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China, a crucial stopover or wintering site for migratory wild birds along the East As...

journal_title：Virology journal

authors： Hu C,Li X,Zhu C,Zhou F,Tang W,Wu D,Li Z,Zhou L,Liu J,Wei X,Cui J,Wang T,He G

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Astroviruses (AstVs) have been reported to infect and cause gastroenteritis in most animal species. Human AstVs were regarded the causative agent of viral diarrhea in children. In dogs, little is known about the epidemiology and clinical significance of AstV infection. FINDINGS:In this study, we collected a...

journal_title：Virology journal

authors： Zhou H,Liu L,Li R,Qin Y,Fang Q,Balasubramaniam VR,Wang G,Wei Z,Ouyang K,Huang W,Chen Y

更新日期：2017-08-17 00:00:00

abstract：BACKGROUND:Chronic HCV is one of the major causes of morbidity and mortality in the present day world. The assessment of disease progression not only provides useful information for diagnosis and therapeutic supervision judgment but also for monitoring disease. Different invasive and non invasive methods are applied to...

journal_title：Virology journal

authors： Ahmad W,Ijaz B,Gull S,Asad S,Khaliq S,Jahan S,Sarwar MT,Kausar H,Sumrin A,Shahid I,Hassan S

更新日期：2011-02-08 00:00:00

abstract：BACKGROUND:Human enterovirus 71 (EV-71) is known of having caused numerous outbreaks of hand-foot-mouth disease, and other clinical manifestations globally. In 2008, 989 EV-71 strains were isolated in Taiwan. RESULTS:In this study, the genetic and antigenic properties of these strains were analyzed and the genetic div...

journal_title：Virology journal

authors： Huang YP,Lin TL,Hsu LC,Chen YJ,Tseng YH,Hsu CC,Fan WB,Yang JY,Chang FY,Wu HS

更新日期：2010-10-20 00:00:00

abstract：BACKGROUND:The major obstacle to cure of HIV type-1 infection is the presence of the HIV reservoir, hidden from the immune system and insensitive to combined antiretroviral therapy (cART). Eradication approaches have been hindered by the difficulty for accurately monitoring its size in vivo, especially in the lymphoid ...

journal_title：Virology journal

authors： Rochat MA,Schlaepfer E,Kuster SP,Li D,Audige A,Ivic S,Fahrny A,Speck RF

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:The deciphering of cellular networks to determine susceptibility to infection by HIV or the related simian immunodeficiency virus (SIV) is a major challenge in infection biology. RESULTS:Here, we have compared gene expression profiles of a human CD4+ T cell line at 24 h after infection with a cell line of t...

journal_title：Virology journal

authors： He FQ,Sauermann U,Beer C,Winkelmann S,Yu Z,Sopper S,Zeng AP,Wirth M

更新日期：2014-08-27 00:00:00

abstract：BACKGROUND:A novel reassortant H7N9 influenza A virus has crossed the species barrier from poultry to cause human infections in China in 2013 and 2014. Rapid detection of the novel H7N9 virus is important to detect this virus in poultry and reduce the risk of an epidemic in birds or humans. FINDINGS:In this study, a m...

journal_title：Virology journal

authors： Xu X,Bao H,Ma Y,Sun J,Zhao Y,Wang Y,Shi J,Zeng X,Li Y,Wang X,Chen H

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:Aedes aegypti is a competent arthropod vector of chikungunya virus (CHIKV). The rate at which the virus disseminate in the vector is limited by temperature of their environment which can be an important determinant of geographical and seasonal limits to transmission by the arthropods in the tropics. This stu...

journal_title：Virology journal

authors： Mbaika S,Lutomiah J,Chepkorir E,Mulwa F,Khayeka-Wandabwa C,Tigoi C,Oyoo-Okoth E,Mutisya J,Ng'ang'a Z,Sang R

更新日期：2016-06-29 00:00:00

abstract：BACKGROUND:Human cytomegalovirus UL114 encodes a uracil-DNA glycosylase homolog that is highly conserved in all characterized herpesviruses that infect mammals. Previous studies demonstrated that the deletion of this nonessential gene delays significantly the onset of viral DNA synthesis and results in a prolonged repl...

journal_title：Virology journal

authors： Prichard MN,Lawlor H,Duke GM,Mo C,Wang Z,Dixon M,Kemble G,Kern ER

更新日期：2005-07-15 00:00:00

abstract：BACKGROUND:The UL54 protein of Duck Enteritis Virus (DEV) is a homolog of herpes simplex virus-1 (HSV-1) immediate-early infectious cell protein 27 (ICP27), a multifunctional protein essential for viral infection. Nonetheless, there is little information on the UL54 protein of DEV. METHODS:The UL54 gene was cloned int...

journal_title：Virology journal

authors： Liu C,Cheng A,Wang M,Chen S,Jia R,Zhu D,Liu M,Sun K,Yang Q,Chen X

更新日期：2015-11-25 00:00:00

abstract：BACKGROUND:Persistent infection of human papillomavirus (HPV) types 16 and 18 causes cervical cancer. To better understand immune responses to the prophylactic vaccine, HPV 16/18 L1 virus-like particles (HPV-VLPs), we investigated B cell epitopes of HPV16 L1-derived peptides. METHODS:Sera from mice immunized with HPV-...

journal_title：Virology journal

authors： Fukui A,Matsueda S,Kawano K,Tsuda N,Komatsu N,Shichijo S,Sasada T,Hattori S,Ushijima K,Itoh K,Kamura T

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:Foot-and mouth disease (FMD) is an acute, febrile, and contagious vesicular disease affecting cloven-hoofed animals. Some animals may become persistent infected carriers when they contact FMD virus (FMDV), and persistent infected animals are a dangerous factor to cause FMD outbreak. FINDINGS:300 OP (oesopha...

journal_title：Virology journal

authors： Bao HF,Li D,Sun P,Zhou Q,Hu J,Bai XW,Fu YF,Lu ZJ,Liu ZX

更新日期：2011-12-14 00:00:00

abstract：BACKGROUND:During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until recently, only a few prokaryotic viruses had been described for one of the lin...

journal_title：Virology journal

authors： San Martín C,van Raaij MJ

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:Human adenoviruses (Ads) have substantial potential for clinical applications in cancer patients. Conditionally replicating adenoviruses (CRAds) include oncolytic adenoviruses in which expression of the immediate early viral transactivator protein E1A is controlled by a cancer cell-selective promoter. To enh...

journal_title：Virology journal

authors： Fontecedro AC,Lutschg V,Eichhoff O,Dummer R,Greber UF,Hemmi S

更新日期：2010-07-29 00:00:00

abstract：BACKGROUND:Production of cassava (Manihot esculenta Crantz), a food security crop in sub-Saharan Africa, is threatened by the spread of cassava brown streak disease (CBSD) which manifests in part as a corky necrosis in the storage root. It is caused by either of two virus species, Cassava brown streak virus (CBSV) and ...

journal_title：Virology journal

authors： Kaweesi T,Kawuki R,Kyaligonza V,Baguma Y,Tusiime G,Ferguson ME

更新日期：2014-12-20 00:00:00

abstract：BACKGROUND:Human caliciviruses (HuCV) are emerging enteric pathogens that are a common cause of diarrhea in humans worldwide. Due to the paucity of information on the molecular characterization of HuCV circulating in Mexico, the aim of this work was to investigate the diversity and molecular epidemiology of the HuCV in...

journal_title：Virology journal

authors： Gómez-Santiago F,Ribas-Aparicio RM,García-Lozano H

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:Panicum streak virus (PanSV; Family Geminiviridae; Genus Mastrevirus) is a close relative of Maize streak virus (MSV), the most serious viral threat to maize production in Africa. PanSV and MSV have the same leafhopper vector species, largely overlapping natural host ranges and similar geographical distribut...

journal_title：Virology journal

authors： Varsani A,Monjane AL,Donaldson L,Oluwafemi S,Zinga I,Komba EK,Plakoutene D,Mandakombo N,Mboukoulida J,Semballa S,Briddon RW,Markham PG,Lett JM,Lefeuvre P,Rybicki EP,Martin DP

更新日期：2009-11-10 00:00:00

abstract：BACKGROUND:Previously, we have reported the isolation and molecular characterization of human Hepatitis C virus genotype 1 (HCV-1) from infected patients. We are now reporting an analysis of HCV obtained from patients infected with HCV genotype 3 (HCV-3) as diagnosed by clinical laboratories. RESULTS:HCV was cultured ...

journal_title：Virology journal

authors： Revie D,Alberti MO,Prichard JG,Kelley AS,Salahuddin SZ

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Viruses Surveillance System (KINRESS) to monitor epidemics of influenza and Severe Acute Respiratory Infe...

journal_title：Virology journal

authors： Kim HM,Lee N,Kim MS,Kang C,Chung YS

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:An extensive outbreak of equine influenza occurred across multiple countries in South America during 2012. The epidemic was first reported in Chile then spread to Brazil, Uruguay and Argentina, where both vaccinated and unvaccinated animals were affected. In Brazil, infections were widespread within 3months ...

journal_title：Virology journal

authors： Alves Beuttemmüller E,Woodward A,Rash A,Dos Santos Ferraz LE,Fernandes Alfieri A,Alfieri AA,Elton D

更新日期：2016-03-19 00:00:00

abstract：BACKGROUND:The Urabe AM9 vaccine strain of mumps virus contains two variants of V protein: VWT (of HN-A1081 viral population) and VGly (of HN-G1081). The V protein is a promoting factor of viral replication by blocking the IFN antiviral pathway. FINDINGS:We studied the relationship between V protein variants and IFN-α...

journal_title：Virology journal

authors： Rosas-Murrieta NH,Santos-López G,Reyes-Leyva J,Jurado FS,Herrera-Camacho I

更新日期：2011-05-13 00:00:00

abstract：:Hepatitis E virus (HEV) is a zoonotic pathogen of which several species of animal were reported as reservoirs. Swine stands out as the major reservoir for HEV infection in humans, as suggested by the close genetic relationship of swine and human virus and cross-species infection of HEV. Up to now, the mechanism of cro...

journal_title：Virology journal

authors： Zhang W,Hua X,Shen Q,Yang S,Yin H,Cui L

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:The membrane topology and molecular mechanisms for endoplasmic reticulum (ER) localization of classical swine fever virus (CSFV) non-structural 2 (NS2) protien is unclear. We attempted to elucidate the subcellular localization, and the molecular mechanisms responsible for the localization of this protein in ...

journal_title：Virology journal

authors： Guo KK,Tang QH,Zhang YM,Kang K,He L

更新日期：2011-05-18 00:00:00

abstract：:We undertook one of the most detailed studies on the distribution of alpha2,3 sialic acid (SA)-galactose (gal) (avian type) and alpha2,6SA-gal (human type) receptors on different tissues of chickens, ducks and turkeys of varying age groups. On the tracheal epithelium, all 3 bird species expressed strong positive stain...

journal_title：Virology journal

authors： Pillai SP,Lee CW

更新日期：2010-01-12 00:00:00

abstract：:Papillomaviruses (PVs) are associated with the development of neoplasias and have been found in several different species, most of them in humans and other mammals. We identified, cloned and sequenced PV DNA from pigmented papilloma-like lesions of a diamond python (Morelia spilota spilota). This represents the first ...

journal_title：Virology journal

authors： Lange CE,Favrot C,Ackermann M,Gull J,Vetsch E,Tobler K

更新日期：2011-09-12 00:00:00

abstract：BACKGROUND:T4 phage is a model species that has contributed broadly to our understanding of molecular biology. T4 DNA replication and packaging share various mechanisms with human double-stranded DNA viruses such as herpes virus. The literature indicates that T4-like phage genomes have permuted terminal sequences, and ...

journal_title：Virology journal

authors： Jiang X,Jiang H,Li C,Wang S,Mi Z,An X,Chen J,Tong Y

更新日期：2011-04-27 00:00:00