Detection and genetic characterization of canine astroviruses in pet dogs in Guangxi, China.

abstract：BACKGROUND:The COVID-19 causing coronavirus is an enveloped RNA virus that utilizes an enzyme RNA dependent RNA polymerase for its replication. Favipiravir (FVP) triphosphate, a purine nucleoside analog, inhibits that enzyme. We have conducted this systematic review and meta-analysis on efficacy and safety of the drug ...

journal_title：Virology journal

authors： Shrestha DB,Budhathoki P,Khadka S,Shah PB,Pokharel N,Rashmi P

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:There has been a recent resurgent interest in bacteriophage biology. Research was initiated to examine Campylobacter jejuni-specific bacteriophage in the Russian Federation to develop alternative control measures for this pathogen. RESULTS:A C. jejuni flagellum-specific phage PV22 from Proteus vulgaris was ...

journal_title：Virology journal

authors： Zhilenkov EL,Popova VM,Popov DV,Zavalsky LY,Svetoch EA,Stern NJ,Seal BS

更新日期：2006-06-27 00:00:00

abstract：BACKGROUND:Human pegivirus (HPgV) is structurally similar to hepatitis C virus (HCV) and was discovered 20 years ago. Its distribution, natural history and exact rule of this viral group in human hosts remain unclear. Our aim was to determine, by deep next-generation sequencing (NGS), the entire genome sequence of HPgV...

journal_title：Virology journal

authors： Soliman HK,Abouelhoda M,El Rouby MN,Ahmed OS,Esmat G,Hassan ZK,Hafez MM,Mehaney DA,Selvaraju M,Darwish RK,Osman YA,Zekri AN

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:It is becoming progressively more understandable that genetic variability of viruses is a major challenge in translating the laboratory findings to clinic. Genetic variability is the underlying cause of variant viral proteins which are not targetable by host immunological machinery. METHODS:500 patients wer...

journal_title：Virology journal

authors： Kanwal S,Mahmood T

更新日期：2014-09-30 00:00:00

abstract：BACKGROUND:Varicella (chickenpox) exhibits a characteristic epidemiological pattern which is associated with climate. In general, primary infections in tropical regions are comparatively less frequent among children than in temperate regions. This peculiarity regarding varicella-zoster virus (VZV) infection among certa...

journal_title：Virology journal

authors： Vaughan G,Rodríguez-Castillo A,Cruz-Rivera MY,Ruiz-Tovar K,Ramírez-González JE,Rivera-Osorio P,Fonseca-Coronado S,Carpio-Pedroza JC,Cazares F,Vazquez-Pichardo M,Anaya L,Escobar-Gutiérrez A

更新日期：2011-07-27 00:00:00

abstract：BACKGROUND:Lassa hemorrhagic fever (LHF) is a neglected tropical disease with significant impact on the health care system, society, and economy of Western and Central African nations where it is endemic. With a high rate of infection that may lead to morbidity and mortality, understanding how the virus interacts with ...

journal_title：Virology journal

authors： Branco LM,Grove JN,Moses LM,Goba A,Fullah M,Momoh M,Schoepp RJ,Bausch DG,Garry RF

更新日期：2010-11-09 00:00:00

abstract：BACKGROUND:Human astroviruses (HAstVs) are one of the important causes of acute gastroenteritis in children. Currently, eight HAstV genotypes have been identified and all but two (HAstV-6 and HAstV-7) have been fully sequenced. We here sequenced and analyzed the complete genome of a HAstV-6 strain (192-BJ07), which was...

journal_title：Virology journal

authors： Guo L,Gonzalez R,Wang W,Li Y,Paranhos-Baccalà G,Vernet G,Wang J

更新日期：2010-02-08 00:00:00

abstract：BACKGROUND:Evaluation of the primary etiologic agents that cause aseptic meningitis outbreaks may provide valuable information regarding the prevention and management of aseptic meningitis. An outbreak of aseptic meningitis occurred from May to June, 2012, in Guangdong Province, China. In order to determine the etiolog...

journal_title：Virology journal

authors： Xiao H,Guan D,Chen R,Chen P,Monagin C,Li W,Su J,Ma C,Zhang W,Ke C

更新日期：2013-08-23 00:00:00

abstract：BACKGROUND:Ebola viruses (EBOVs) cause severe hemorrhagic fever with a high mortality rate. At present, there are no licensed vaccines or efficient therapies to combat EBOV infection. Previous studies have shown that both humoral and cellular immune responses are crucial for controlling Ebola infection. CD8+ T cells pl...

journal_title：Virology journal

authors： Wu S,Yu T,Song X,Yi S,Hou L,Chen W

更新日期：2012-06-13 00:00:00

abstract：BACKGROUND:PCR-based detection and identification of viruses assumes a known, relatively stable genome. Unfortunately, high mutation rates may lead to extensive changes in viral nucleic acid sequences making dedicated PCR primer use problematic. Furthermore, in bioterrorism, viral consensus sequences can be genetically...

journal_title：Virology journal

authors： Clem AL,Sims J,Telang S,Eaton JW,Chesney J

更新日期：2007-06-28 00:00:00

abstract：:Cyclooxygenases (COXs) play a significant role in many different viral infections with respect to replication and pathogenesis. Here we investigated the role of COXs in the mouse hepatitis coronavirus (MHV) infection cycle. Blocking COX activity by different inhibitors or by RNA interference affected MHV infection in ...

journal_title：Virology journal

authors： Raaben M,Einerhand AW,Taminiau LJ,van Houdt M,Bouma J,Raatgeep RH,Büller HA,de Haan CA,Rossen JW

更新日期：2007-06-07 00:00:00

abstract：BACKGROUND:Foot-and mouth disease (FMD) is an acute, febrile, and contagious vesicular disease affecting cloven-hoofed animals. Some animals may become persistent infected carriers when they contact FMD virus (FMDV), and persistent infected animals are a dangerous factor to cause FMD outbreak. FINDINGS:300 OP (oesopha...

journal_title：Virology journal

authors： Bao HF,Li D,Sun P,Zhou Q,Hu J,Bai XW,Fu YF,Lu ZJ,Liu ZX

更新日期：2011-12-14 00:00:00

abstract：:Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated t...

journal_title：Virology journal

authors： Adlhoch C,Kaiser M,Ellerbrok H,Pauli G

更新日期：2010-07-25 00:00:00

abstract：BACKGROUND:The threat of recurring influenza pandemics caused by new viral strains and the occurrence of escape mutants necessitate the search for potent therapeutic targets. The dependence of viruses on cellular factors provides a weak-spot in the viral multiplication strategy and a means to interfere with viral multi...

journal_title：Virology journal

authors： Sun L,Hemgård GV,Susanto SA,Wirth M

更新日期：2010-05-26 00:00:00

abstract：BACKGROUND:Herpesviruses are ubiquitous pathogens that infect and cause recurrent disease in multiple animal species. Feline herpesvirus-1 (FHV-1), a member of the alphaherpesvirus family, causes respiratory illness and conjunctivitis, and approximately 80% of domestic cats are latently infected. Oral administration of...

journal_title：Virology journal

authors： Semenkow SL,Johnson NM,Maggs DJ,Margulies BJ

更新日期：2014-02-22 00:00:00

abstract：BACKGROUND:The binding of viral-specific antibodies to cell-surface antigens usually results in down modulation of the antigen through redistribution of antigens into patches that subsequently may be internalized by endocytosis or may form caps that can be expelled to the extracellular space. Here, by use of confocal-l...

journal_title：Virology journal

authors： Sarmiento RE,Tirado RG,Valverde LE,Gómez-Garcia B

更新日期：2007-07-03 00:00:00

abstract：BACKGROUND:A variety of interactions between up to three different movement proteins (MPs), the coat protein (CP) and genomic DNA mediate the inter- and intra-cellular movement of geminiviruses in the genus Begomovirus. Although movement of viruses in the genus Mastrevirus is less well characterized, direct interaction...

journal_title：Virology journal

authors： van der Walt E,Palmer KE,Martin DP,Rybicki EP

更新日期：2008-05-20 00:00:00

abstract：:Here we report the case of a 54-year old, immunocompetent German patient with primary varicella whose Varicella-Zoster Virus (VZV)-specific T-cell responses could be detected early in infection and before the onset of seroconversion. This case demonstrates that the detection of VZV-specific T-cells may under certain c...

journal_title：Virology journal

authors： Baiker A,Haase R,Eberle J,Vizoso Pinto MG,Pfrepper KI,Petrich A,Deml L,Campe H,Nitschko H,Jaeger G

更新日期：2010-03-06 00:00:00

abstract：BACKGROUND:A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of antibodies titers after vaccination. METHOD:The microspheres coated with purified recombinant glycop...

journal_title：Virology journal

authors： Wang H,Cong F,Guan J,Xiao L,Zhu Y,Lian Y,Huang R,Chen M,Guo P

更新日期：2018-09-21 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in situations where the immune system is immature or compromised. HCMV immediate early (IE) gene expression is stimulated by the virion phosphoprotein pp71, encoded by open reading frame (ORF) UL82, and this transactivation activity...

journal_title：Virology journal

authors： Nicholson IP,Sutherland JS,Chaudry TN,Blewett EL,Barry PA,Nicholl MJ,Preston CM

更新日期：2009-05-27 00:00:00

abstract：:The occurrence of homologous recombination in influenza viruses has been under some debate recently. To determine the extent of homologous recombination in influenza C virus, recombination analyses of all available gene sequences of influenza C virus were carried out. No recombination signal was found. With the previo...

journal_title：Virology journal

authors： Han GZ,Boni MF,Li SS

更新日期：2010-09-14 00:00:00

abstract：BACKGROUND:Patchouli alcohol (PA) is a tricyclic sesquiterpene extracted from Pogostemonis Herba, which is a traditional Chinese medicine used for therapy of inflammatory diseases. Recent studies have shown that PA has various pharmacological activities, including anti-bacterial and anti-viral effects. METHODS:In this...

journal_title：Virology journal

authors： Yu Y,Zhang Y,Wang S,Liu W,Hao C,Wang W

更新日期：2019-12-23 00:00:00

abstract：:Bats have been recognized as the natural reservoirs of a large variety of viruses. Special attention has been paid to bat coronaviruses as the two emerging coronaviruses which have caused unexpected human disease outbreaks in the 21st century, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Re...

journal_title：Virology journal

authors： Hu B,Ge X,Wang LF,Shi Z

更新日期：2015-12-22 00:00:00

abstract：BACKGROUND:Aleutian mink disease has major economic consequences on the mink farming industry worldwide, as it causes a disease that affects both the fur quality and the health and welfare of the mink. The virus causing this disease is a single-stranded DNA virus of the genus Amdoparvovirus belonging to the family of P...

journal_title：Virology journal

authors： Ryt-Hansen P,Hagberg EE,Chriél M,Struve T,Pedersen AG,Larsen LE,Hjulsager CK

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:Sheeppox (SPP) and goatpox (GTP) caused by sheeppox virus (SPPV) and goatpox virus (GTPV), respectively of the genus Capripoxvirus in the family Poxviridae, are severely afflicting small ruminants' production systems in Africa and Asia. In endemic areas, SPP and GTP are controlled using vaccination with live...

journal_title：Virology journal

authors： Chibssa TR,Grabherr R,Loitsch A,Settypalli TBK,Tuppurainen E,Nwankpa N,Tounkara K,Madani H,Omani A,Diop M,Cattoli G,Diallo A,Lamien CE

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Protease inhibitors (PIs) to treat hepatitis C (HCV) virus infection have been approved and others are under development. RESULTS:The aims of this study were to illustrate natural polymorphisms in the HCV protease and measure the frequency of PI resistance mutations in different HCV genotypes from PI-naïve ...

journal_title：Virology journal

authors： Paolucci S,Fiorina L,Piralla A,Gulminetti R,Novati S,Barbarini G,Sacchi P,Gatti M,Dossena L,Baldanti F

更新日期：2012-10-24 00:00:00

abstract：BACKGROUND:HIV-1 is highly variable genetically and at protein level, a property it uses to subvert antiviral immunity and treatment. The aim of this study was to assess if HIV subtype differences were associated with variations in glycosylation patterns and co-receptor tropism among HAART patients experiencing differe...

journal_title：Virology journal

authors： Kitawi RC,Hunja CW,Aman R,Ogutu BR,Muigai AW,Kokwaro GO,Ochieng W

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND/AIM:Hepatitis C virus (HCV) has been the subject of intense research and clinical investigation as its major role in human disease has emerged. HCV circulates in vivo as a complex population of different but closely related viral variants, commonly referred to as a quasispecies. The extent to which recombina...

journal_title：Virology journal

authors： Moreno MP,Casane D,López L,Cristina J

更新日期：2006-10-24 00:00:00

abstract：:Secondary pneumonia due to Staphylococcus aureus (S. aureus) causes significant morbidity and mortality. The aim of the research was designed a novel DNA vaccine encoding the Mycobacterium tuberculosis secreted antigen Ag85A fused with the influenza A virus (IAV) HA2 protein to provide protection against both influenz...

journal_title：Virology journal

authors： Dai J,Pei D,Wang B,Kuang Y,Ren L,Cao K,Zuo B,Shao J,Li S,Jiang Z,Li H,Li M

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:Tembusu virus is a newly emerging flavivirus that caused egg-drop syndrome in ducks in China. TMUV envelope protein is a major structural protein locates at the surface of tembusu virus particle. During tembusu virus infection, envelope protein plays a pivotal role in induction of neutralizing antibody. Howe...

journal_title：Virology journal

authors： Zhao D,Han K,Huang X,Zhang L,Wang H,Liu N,Tian Y,Liu Q,Yang J,Liu Y,Li Y

更新日期：2018-09-17 00:00:00