Screening and identification of B-cell epitopes within envelope protein of tembusu virus.

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is the leading viral pathogen associated with bronchiolitis and lower respiratory tract disease in infants and young children worldwide. The respiratory epithelium is the primary initiator of pulmonary inflammation in RSV infections, which cause significant perturbations of ...

journal_title：Virology journal

authors： Zhao D,Peng D,Li L,Zhang Q,Zhang C

更新日期：2008-10-06 00:00:00

abstract：BACKGROUND:The membrane topology and molecular mechanisms for endoplasmic reticulum (ER) localization of classical swine fever virus (CSFV) non-structural 2 (NS2) protien is unclear. We attempted to elucidate the subcellular localization, and the molecular mechanisms responsible for the localization of this protein in ...

journal_title：Virology journal

authors： Guo KK,Tang QH,Zhang YM,Kang K,He L

更新日期：2011-05-18 00:00:00

abstract：:Fatal influenza A virus infection is a major threat to public health throughout the world. Lung macrophages and neutrophils have critical roles for both the pathogenesis and viral clearance of fatal viral infections. These are complicated by the interaction of innate immunity and adaptive immunity against viral infect...

journal_title：Virology journal

authors： Lv J,Hua Y,Wang D,Liu A,An J,Li A,Wang Y,Wang X,Jia N,Jiang Q

更新日期：2014-03-26 00:00:00

abstract：:Papillomaviruses (PVs) are associated with the development of neoplasias and have been found in several different species, most of them in humans and other mammals. We identified, cloned and sequenced PV DNA from pigmented papilloma-like lesions of a diamond python (Morelia spilota spilota). This represents the first ...

journal_title：Virology journal

authors： Lange CE,Favrot C,Ackermann M,Gull J,Vetsch E,Tobler K

更新日期：2011-09-12 00:00:00

abstract：BACKGROUND:During October 2010, Egypt reported an outbreak of acute hemorrhagic conjunctivitis (AHC). A total of 1831 cases were reported from three governorates; 1703 cases in El Daqahliya, 92 cases in Port Said, and 36 in Damietta. The purpose of this study was to identify and characterize the causative agent associa...

journal_title：Virology journal

authors： Ayoub EA,Shafik CF,Gaynor AM,Mohareb EW,Amin MA,Yassin AS,El-Refaey S,Genedy M,Kandeel A

更新日期：2013-03-25 00:00:00

abstract：BACKGROUND:Few studies have used quantitative polymerase chain reaction (qPCR) as an approach to measure virus neutralization assay endpoints. Its lack of use may not be surprising considering that sample nucleic acid extraction and purification can be expensive, labor-intensive, and rate-limiting. METHODS:Virus/antib...

journal_title：Virology journal

authors： Varada JC,Teferedegne B,Crim RL,Mdluli T,Audet S,Peden K,Beeler J,Murata H

更新日期：2013-06-15 00:00:00

abstract：BACKGROUND:The threat of recurring influenza pandemics caused by new viral strains and the occurrence of escape mutants necessitate the search for potent therapeutic targets. The dependence of viruses on cellular factors provides a weak-spot in the viral multiplication strategy and a means to interfere with viral multi...

journal_title：Virology journal

authors： Sun L,Hemgård GV,Susanto SA,Wirth M

更新日期：2010-05-26 00:00:00

abstract：BACKGROUND:The BK Polyomavirus (BKPyV) and JC polyomavirus (JCPyV) infections are widespread in human population and have been associated with severe kidney and brain disorders, respectively. The viruses remain latent primarily in reno-urinary tract, reactivating only in case of a compromised immune system. The seroepi...

journal_title：Virology journal

authors： Hussain I,Tasneem F,Umer M,Pervaiz A,Raza M,Arshad MI,Shahzad N

更新日期：2017-04-24 00:00:00

abstract：:Hepatitis C virus (HCV) is endemic worldwide, and it causes cirrhosis and other complications that often lead to death; nevertheless, our knowledge of the disease and its mechanisms is limited. HCV is most common in underdeveloped nations, including many in Africa and Asia. The virus is usually transmitted by parenter...

journal_title：Virology journal

authors： Aman W,Mousa S,Shiha G,Mousa SA

更新日期：2012-03-02 00:00:00

abstract：BACKGROUND:Xenotransplantation using pig cells, tissues and organs may help to overcome the shortage of human tissues and organs for the treatment of tissue and organ failure. Progress in the prevention of immunological rejection using genetically modified pigs and new, more effective, immunosuppression regimens will a...

journal_title：Virology journal

authors： Denner J

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) encodes several proteins that interfere with the host cell antiviral response. Previously, the serine protease NS3/4A was shown to inhibit IFN-beta gene expression by blocking dsRNA-activated retinoic acid-inducible gene I (RIG-I) and Toll-like receptor 3 (TLR3)-mediated signaling pat...

journal_title：Virology journal

authors： Kaukinen P,Sillanpää M,Kotenko S,Lin R,Hiscott J,Melén K,Julkunen I

更新日期：2006-09-01 00:00:00

abstract：:Retroviral transduction involves integrase-dependent linkage of viral and host DNA that leaves an intermediate that requires post-integration repair (PIR). We and others proposed that PIR hijacks the host cell double-strand DNA break (DSB) repair pathways. Nevertheless, the geometry of retroviral DNA integration diffe...

journal_title：Virology journal

authors： Smith JA,Wang FX,Zhang H,Wu KJ,Williams KJ,Daniel R

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Recently, human leukocyte antigen (HLA) class-II gene polymorphisms have been reported to be related to Hepatitis C virus (HCV) infection and chronicity. The objective of this study was to explore the relationship of HLA-DP rs9277535 and HLA-DQ rs7453920 with the outcomes of HCV infection. METHODS:The rs927...

journal_title：Virology journal

authors： Huang P,Fan H,Tian T,Liao P,Li J,Yu R,Xia X,Feng Y,Wang J,Liu Y,Zhang Y,Yue M

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:Ebola viruses (EBOVs) cause severe hemorrhagic fever with a high mortality rate. At present, there are no licensed vaccines or efficient therapies to combat EBOV infection. Previous studies have shown that both humoral and cellular immune responses are crucial for controlling Ebola infection. CD8+ T cells pl...

journal_title：Virology journal

authors： Wu S,Yu T,Song X,Yi S,Hou L,Chen W

更新日期：2012-06-13 00:00:00

abstract：BACKGROUND:H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population. Vaccination is the best strategy to control H5N1 HPAIV infection in poultry and transmission to human population. The aim of this study is to identif...

journal_title：Virology journal

authors： Zhang W,Tu J,Zhao Z,Chen H,Jin M

更新日期：2012-05-23 00:00:00

abstract：BACKGROUND:A novel reassortant H7N9 influenza A virus has crossed the species barrier from poultry to cause human infections in China in 2013 and 2014. Rapid detection of the novel H7N9 virus is important to detect this virus in poultry and reduce the risk of an epidemic in birds or humans. FINDINGS:In this study, a m...

journal_title：Virology journal

authors： Xu X,Bao H,Ma Y,Sun J,Zhao Y,Wang Y,Shi J,Zeng X,Li Y,Wang X,Chen H

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:Diverse vaccination outcomes and protection levels among different populations pose a serious challenge to the development of an effective malaria vaccine. Co-infections are among many factors associated with immune dysfunction and sub-optimal vaccination outcomes. Chronic, asymptomatic viral infections can ...

journal_title：Virology journal

authors： Tumbo AM,Schindler T,Dangy JP,Orlova-Fink N,Bieri JR,Mpina M,Milando FA,Juma O,Hamad A,Nyakarungu E,Chemba M,Mtoro A,Ramadhan K,Olotu A,Makweba D,Mgaya S,Stuart K,Perreau M,Stapleton JT,Jongo S,Hoffman SL,Tanner

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:The epidemic pattern of respiratory syncytial virus (RSV) is quite different in regions of Europe (biennial epidemics in alternating cycles of approximately 9 and 15 months) than in the Western Hemisphere (annual epidemics). In order to determine if these differences are accounted for by the circulation of d...

journal_title：Virology journal

authors： Mlinaric-Galinovic G,Vojnovic G,Cepin-Bogovic J,Bace A,Bozikov J,Welliver RC,Wahn U,Cebalo L

更新日期：2009-09-07 00:00:00

abstract：:A TaqMan-based real-time polymerase chain reaction (PCR) assay was devised for the detection of porcine parvovirus (PPV). Two primers and a TaqMan probe for the non-structural protein NS1 gene were designed. The detection limit was 1 x 10² DNA copies/μL, and the assay was linear in the range of 1 x 10² to 1 x 10⁹ copi...

journal_title：Virology journal

authors： Song C,Zhu C,Zhang C,Cui S

更新日期：2010-12-02 00:00:00

abstract：BACKGROUND:hyaluronic acid (HA), a non-sulphated glycosaminoglycan, is present in synovial fluid, vitreous humour serum and many connective tissues. Pharmaceutical preparations of HA are used in clinical practice for wound healing, joint pain, kerato-conjunctivitis, asthma, mouth care, oesophageal-reflux, and gastritis...

journal_title：Virology journal

authors： Cermelli C,Cuoghi A,Scuri M,Bettua C,Neglia RG,Ardizzoni A,Blasi E,Iannitti T,Palmieri B

更新日期：2011-03-25 00:00:00

abstract：BACKGROUND:Polyomaviruses (PyVs) have a wide range of hosts, from humans to fish, and their effects on hosts vary. The differences in the infection characteristics of PyV with respect to the host are assumed to be influenced by the biochemical function of the LT-Ag protein, which is related to the cytopathic effect and...

journal_title：Virology journal

authors： Cho M,Kim H,Son HS

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:Finding new biomarkers for the early detection of cervical cancer is an essential requirement in this field. In this study, we aimed to evaluate the expression level of potential biomarkers in progression of cervical cancer in patients with cervical cancer compared to normal subjects. METHODS:The expression...

journal_title：Virology journal

authors： Farzanehpour M,Mozhgani SH,Jalilvand S,Faghihloo E,Akhavan S,Salimi V,Azad TM

更新日期：2019-10-07 00:00:00

abstract：BACKGROUND:Infection with Chikungunya alphavirus (CHIKV) can cause severe arthralgia and chronic arthritis in humans with persistence of the virus in perivascular macrophages of the synovial membrane by mechanisms largely ill-characterized. FINDINGS:We herein analysed the innate immune response (cytokine and programme...

journal_title：Virology journal

authors： Kumar S,Jaffar-Bandjee MC,Giry C,Connen de Kerillis L,Merits A,Gasque P,Hoarau JJ

更新日期：2012-12-19 00:00:00

abstract：BACKGROUND:The amino terminus of the tobacco etch virus (TEV) capsid protein is located on the external surface of infectious TEV particles, as proposed by previous studies and an in silico model. The epsilon amino groups on the exposed lysine residues are available for chemical conjugation to any given protein, and ca...

journal_title：Virology journal

authors： Manuel-Cabrera CA,Márquez-Aguirre A,Rodolfo HG,Ortiz-Lazareno PC,Chavez-Calvillo G,Carrillo-Tripp M,Silva-Rosales L,Gutiérrez-Ortega A

更新日期：2012-03-27 00:00:00

abstract：BACKGROUND:Some genotypes of human papillomaviruses can infect the genital tract and they are important infectious agents which their oncogenicity is regardable. Thus the aim of this study was to determine the prevalence of various genital human papillomaviruses (HPV) among women being subjected to routine pap smear te...

journal_title：Virology journal

authors： Zandi K,Eghbali SS,Hamkar R,Ahmadi S,Ramedani E,Deilami I,Nejad HA,Farshadpour F,Rastian Z

更新日期：2010-03-22 00:00:00

abstract：:In Pakistan, there are estimated 7-9 million carriers of hepatitis B virus (HBV) with a carrier rate of 3-5%. This article reviews the available literature about the prevalence, risk factors, awareness status and genotypes of the HBV in Pakistan by using key words; HBV prevalence, risk factors, awareness status and ge...

journal_title：Virology journal

authors： Ali M,Idrees M,Ali L,Hussain A,Ur Rehman I,Saleem S,Afzal S,Butt S

更新日期：2011-03-06 00:00:00

abstract：:During the outbreak of SARS in 2002/3, a prototype virus was isolated from a patient in Frankfurt/Germany (strain Frankfurt-1). As opposed to all other SARS-Coronavirus strains, Frankfurt-1 has a 45-nucleotide deletion in the transmembrane domain of its ORF 7b protein. When over-expressed in HEK 293 cells, the full-le...

journal_title：Virology journal

authors： Pfefferle S,Krähling V,Ditt V,Grywna K,Mühlberger E,Drosten C

更新日期：2009-08-24 00:00:00

abstract：:From April 2007 to March 2008, cloacal swabs were obtained from 246 casualty raptors recovered by various wildlife rehabilitation centers in the United States. The swabs were placed in a virus transport medium and transported to the laboratory on ice packs. At the laboratory, the samples were pooled with each pool con...

journal_title：Virology journal

authors： Goyal SM,Jindal N,Chander Y,Ramakrishnan MA,Redig PT,Sreevatsan S

更新日期：2010-07-28 00:00:00

abstract：BACKGROUND:Yearly influenza virus mutations potentially affect the performance of molecular assays, if nucleic acid changes involve the sequences in the assay. Because individual patient viral loads depend on variables such as duration of illness, specimen type, age, and immunosuppression, we examined seasonal populati...

journal_title：Virology journal

authors： Rand KH,Pieretti M,Arcenas R,Beal SG,Houck H,Boslet E,Lednicky JA

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Cotton blue disease (CBD), an important global cotton crop pathology responsible for major economic losses, is prevalent in the major cotton-producing states of Brazil. Typical CBD symptoms include stunting due to internodal shortening, leaf rolling, intense green foliage, and yellowing veins. Atypical CBD s...

journal_title：Virology journal

authors： Silva TF,Corrêa RL,Castilho Y,Silvie P,Bélot JL,Vaslin MF

更新日期：2008-10-20 00:00:00