In vitro evaluation of antiviral and virucidal activity of a high molecular weight hyaluronic acid.

abstract：BACKGROUND:Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parenterally and occurs both as a primary infection and as reactivation in immunocompromised individuals. C...

journal_title：Virology journal

authors： Burbelo PD,Issa AT,Ching KH,Exner M,Drew WL,Alter HJ,Iadarola MJ

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Porcine epidemic diarrhea virus (PEDV) is the main causative agent of porcine epidemic diarrhea (PED). Since December 2010, a large-scale outbreak of diarrhea has been observed in swine farms in China. Accumulated evidence indicates that this large-scale outbreak of diarrhea were caused by highly virulent PE...

journal_title：Virology journal

authors： Lin H,Chen L,Gao L,Yuan X,Ma Z,Fan H

更新日期：2016-04-22 00:00:00

abstract：:Herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases worldwide. The first time infection of the mother may lead to severe illness in pregnancy and may be associated with virus transmission from mother to foetus/newborn. Since the incidence of this sexually transmitted infe...

journal_title：Virology journal

authors： Anzivino E,Fioriti D,Mischitelli M,Bellizzi A,Barucca V,Chiarini F,Pietropaolo V

更新日期：2009-04-06 00:00:00

abstract：BACKGROUND:We have characterised a new highly divergent geminivirus species, Eragrostis curvula streak virus (ECSV), found infecting a hardy perennial South African wild grass. ECSV represents a new genus-level geminivirus lineage, and has a mixture of features normally associated with other specific geminivirus genera...

journal_title：Virology journal

authors： Varsani A,Shepherd DN,Dent K,Monjane AL,Rybicki EP,Martin DP

更新日期：2009-03-25 00:00:00

abstract：BACKGROUND:The Unique Long 26 (UL26) and UL26.5 proteins of herpes simplex virus are known to function during the assembly of the viruses. However, for duck enteritis virus (DEV), which is an unassigned member of the family Herpesviridae, little information is available about the function of the two proteins. In this s...

journal_title：Virology journal

authors： Liu X,Han Z,Shao Y,Yu D,Li H,Wang Y,Kong X,Liu S

更新日期：2010-09-13 00:00:00

abstract：BACKGROUND:A vaccine against all four dengue virus (DENV) serotypes includes the formulation of one genotype of each serotype. Although genetic similarities among genotypes within a serotype are higher as compared to those among serotypes, differences in the immunogenicity of the included genotypes would be a critical ...

journal_title：Virology journal

authors： Azami NAM,Moi ML,Ami Y,Suzaki Y,Lim CK,Taniguchi S,Saijo M,Takasaki T,Kurane I

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Some genotypes of human papillomaviruses can infect the genital tract and they are important infectious agents which their oncogenicity is regardable. Thus the aim of this study was to determine the prevalence of various genital human papillomaviruses (HPV) among women being subjected to routine pap smear te...

journal_title：Virology journal

authors： Zandi K,Eghbali SS,Hamkar R,Ahmadi S,Ramedani E,Deilami I,Nejad HA,Farshadpour F,Rastian Z

更新日期：2010-03-22 00:00:00

abstract：BACKGROUND:The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain. RESULTS:We have addressed this issue in ...

journal_title：Virology journal

authors： Garg H,Joshi A,Ye C,Shankar P,Manjunath N

更新日期：2011-01-21 00:00:00

abstract：BACKGROUND:Cervical cancer is a major public health problem worldwide. While Romania has the highest incidence of cervical cancer in Europe, the prevalence of HPV has not been evaluated. We report the first data on HPV prevalence and type distribution in Northeast Romania. METHODS:HPV prevalence and genotype distribut...

journal_title：Virology journal

authors： Ursu RG,Onofriescu M,Nemescu D,Iancu LS

更新日期：2011-12-22 00:00:00

abstract：:Virus taxonomy at present is best characterized as a categorization of convenience, without a firm basis in the principles of evolutionary biology. Specifically, virus species definitions appear to depend more on tradition and popular opinion among virologists than on firm, quantitative biological evidence. I suggest ...

journal_title：Virology journal

authors： Peterson AT

更新日期：2014-07-23 00:00:00

abstract：BACKGROUND:The human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein. Though mutants lacking agnoprotein are severely reduced in producing infectious virions, the exact function of this peptide remains incompletely understood. To elucidate the function of agnoprotein, we searched for novel ...

journal_title：Virology journal

authors： Gerits N,Johannessen M,Tümmler C,Walquist M,Kostenko S,Snapkov I,van Loon B,Ferrari E,Hübscher U,Moens U

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Human T-cell Leukemia Virus type 1 (HTLV-1) is the etiological agent of tropical spastic paraparesis/HTLV-associated myelopathy (HAM/TSP) that can be identified in around 0.25%-3.8% of the infected population. Disease progression can be monitored by the proviral load and may depend on genetic factors, howeve...

journal_title：Virology journal

authors： Mota-Miranda AC,Barreto FK,Amarante MF,Batista E,Monteiro-Cunha JP,Farre L,Galvão-Castro B,Alcantara LC

更新日期：2013-03-06 00:00:00

abstract：:The replication of porcine endogenous retrovirus (PERV) in human cell lines suggests a potential infectious risk in xenotransplantation. PERV isolated from human cells following cocultivation with porcine peripheral blood mononuclear cells is a recombinant of PERV-A and PERV-C. We describe two different recombinant PE...

journal_title：Virology journal

authors： Martin SI,Wilkinson R,Fishman JA

更新日期：2006-11-02 00:00:00

abstract：BACKGROUND:Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (UL) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, we constructed a deletion mutant of ORF58 (pOka-BACDelta58) from the Oka parental genome cloned i...

journal_title：Virology journal

authors： Yoshii H,Sadaoka K,Matsuura M,Nagaike K,Takahashi M,Yamanishi K,Mori Y

更新日期：2008-04-30 00:00:00

abstract：BACKGROUND:The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Viruses Surveillance System (KINRESS) to monitor epidemics of influenza and Severe Acute Respiratory Infe...

journal_title：Virology journal

authors： Kim HM,Lee N,Kim MS,Kang C,Chung YS

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:According to international guidelines, HPV DNA tests represent a valid alternative to Pap Test for primary cervical cancer screening, provided that they guarantee balanced clinical sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more severe lesions. The aim of this study was to ...

journal_title：Virology journal

authors： Iacobellis M,Violante C,Notarachille G,Simone A,Scarfì R,Giuffrè G

更新日期：2018-03-20 00:00:00

abstract：BACKGROUND:PHYVV and PepGMV are plant viruses reported in Mexico and Southern US as causal agents of an important pepper disease known as "rizado amarillo". Mixed infections with PHYVV and PepGMV have been reported in several hosts over a wide geographic area. Previous work suggested that these viruses might interact a...

journal_title：Virology journal

authors： Rentería-Canett I,Xoconostle-Cázares B,Ruiz-Medrano R,Rivera-Bustamante RF

更新日期：2011-03-08 00:00:00

abstract：BACKGROUND:Sequence and structural elements in the 3'-untranslated region (UTR) of Japanese encephalitis virus (JEV) are known to regulate translation and replication. We previously reported an abundant accumulation of small subgenomic flaviviral RNA (sfRNA) which is collinear with the highly conserved regions of the 3...

journal_title：Virology journal

authors： Fan YH,Nadar M,Chen CC,Weng CC,Lin YT,Chang RY

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:About half of the world's population are living in the endemic area of dengue viruses implying that a rapid-mass vaccination may be required. In addition, a major target of dengue vaccine are children, thus, a needle-free administration is more attractive. These problems may be overcome by the alternative ro...

journal_title：Virology journal

authors： Nantachit N,Sunintaboon P,Ubol S

更新日期：2016-08-18 00:00:00

abstract：BACKGROUND:Avian hepatitis E virus (aHEV) has been associated with hepatitis-splenomegaly syndrome (HSS) in chickens along with asymptomatic subclinical infection in many cases. So far, four genotypes have been described, which cause infection in chickens, specifically in broiler breeders and layer chickens. In the pre...

journal_title：Virology journal

authors： Iqbal T,Rashid U,Idrees M,Afroz A,Kamili S,Purdy MA

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:Tanganya virus (TGNV), the only shrew-associated hantavirus reported to date from sub-Saharan Africa, is harbored by the Therese's shrew (Crocidura theresae), and is phylogenetically distinct from Thottapalayam virus (TPMV) in the Asian house shrew (Suncus murinus) and Imjin virus (MJNV) in the Ussuri white-...

journal_title：Virology journal

authors： Kang HJ,Kadjo B,Dubey S,Jacquet F,Yanagihara R

更新日期：2011-07-28 00:00:00

abstract：BACKGROUND:Since its first appearance in the USA in 1999, West Nile virus (WNV) has spread in the Western hemisphere and continues to represent an important public health concern. In the absence of effective treatment, there is a medical need for the development of a safe and efficient vaccine. Live attenuated WNV vacc...

journal_title：Virology journal

authors： Spohn G,Jennings GT,Martina BE,Keller I,Beck M,Pumpens P,Osterhaus AD,Bachmann MF

更新日期：2010-07-06 00:00:00

abstract：:Lytic bacteriophage 0305phi8-36 forms visually observed aggregates during plaque formation. Aggregates intrinsically lower propagation potential. In the present study, the following observations indicate that lost propagation potential is regained with time: (1) Aggregates sometimes concentrate at the edge of clear pl...

journal_title：Virology journal

authors： Serwer P,Hayes SJ,Lieman K

更新日期：2007-12-04 00:00:00

abstract：BACKGROUND:Both regulatory T cells (Tregs) and PD-1/PD-L1 pathway were critically involved in HCV viral persistence. However, the association between them was not well investigated. Herein, we aimed to investigate the distributional profiles of Tregs subsets and association between PD-1 expression on these subsets and ...

journal_title：Virology journal

authors： Shen T,Zheng J,Liang H,Xu C,Chen X,Zhang T,Xu Q,Lu F

更新日期：2011-06-07 00:00:00

abstract：BACKGROUND:Citrus sudden death (CSD), a disease that rapidly kills orange trees, is an emerging threat to the Brazilian citrus industry. Although the causal agent of CSD has not been definitively determined, based on the disease's distribution and symptomatology it is suspected that the agent may be a new strain of Cit...

journal_title：Virology journal

authors： Gomes CP,Nagata T,de Jesus WC Jr,Neto CR,Pappas GJ Jr,Martin DP

更新日期：2008-01-16 00:00:00

abstract：BACKGROUND:The membrane topology and molecular mechanisms for endoplasmic reticulum (ER) localization of classical swine fever virus (CSFV) non-structural 2 (NS2) protien is unclear. We attempted to elucidate the subcellular localization, and the molecular mechanisms responsible for the localization of this protein in ...

journal_title：Virology journal

authors： Guo KK,Tang QH,Zhang YM,Kang K,He L

更新日期：2011-05-18 00:00:00

abstract：BACKGROUND:Viruses interact with host cellular factors to construct a more favourable environment for their efficient replication. Expression of cyclophilin B (CypB), a cellular peptidyl-prolyl cis-trans isomerase (PPIase), was found to be significantly up-regulated. Recently, a number of studies have shown that CypB i...

journal_title：Virology journal

authors： Zhao K,Li J,He W,Song D,Zhang X,Zhang D,Zhou Y,Gao F

更新日期：2017-06-15 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) congenital infection is the major viral cause of well-documented birth defects in human. Because CMV is species-specific, the main obstacle to developing animal models for congenital infection is the difference in placental architecture, which preludes virus transmission across the plac...

journal_title：Virology journal

authors： Loh HS,Mohd-Lila MA,Abdul-Rahman SO,Kiew LJ

更新日期：2006-06-01 00:00:00

abstract：:We undertook one of the most detailed studies on the distribution of alpha2,3 sialic acid (SA)-galactose (gal) (avian type) and alpha2,6SA-gal (human type) receptors on different tissues of chickens, ducks and turkeys of varying age groups. On the tracheal epithelium, all 3 bird species expressed strong positive stain...

journal_title：Virology journal

authors： Pillai SP,Lee CW

更新日期：2010-01-12 00:00:00

abstract：BACKGROUND:The family Mesoniviridae (order Nidovirales) comprises of a group of positive-sense, single-stranded RNA ([+]ssRNA) viruses isolated from mosquitoes. FINDINGS:Thirteen novel insect-specific virus isolates were obtained from mosquitoes collected in Indonesia, Thailand and the USA. By electron microscopy, the...

journal_title：Virology journal

authors： Vasilakis N,Guzman H,Firth C,Forrester NL,Widen SG,Wood TG,Rossi SL,Ghedin E,Popov V,Blasdell KR,Walker PJ,Tesh RB

更新日期：2014-05-20 00:00:00