Small noncoding RNA modulates Japanese encephalitis virus replication and translation in trans.

abstract：BACKGROUND:Hepatitis C virus (HCV) encodes several proteins that interfere with the host cell antiviral response. Previously, the serine protease NS3/4A was shown to inhibit IFN-beta gene expression by blocking dsRNA-activated retinoic acid-inducible gene I (RIG-I) and Toll-like receptor 3 (TLR3)-mediated signaling pat...

journal_title：Virology journal

authors： Kaukinen P,Sillanpää M,Kotenko S,Lin R,Hiscott J,Melén K,Julkunen I

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:HIV-1 subtype B' isolates have been predominantly circulating in China. Their intra- and inter-subtype neutralization sensitivity to autologous and heterologous plasmas has not been well studied. RESULTS:Twelve HIV-1 B' clinical isolates obtained from patients were tested for their intra- and inter-subtype ...

journal_title：Virology journal

authors： OuYang Y,Sun J,Huang Y,Lu L,Xu W,Hu X,Hong K,Jiang S,Shao Y,Ma L

更新日期：2013-01-05 00:00:00

abstract：BACKGROUND:Hepatitis C Virus (HCV) infected patients are frequently repeatedly exposed to the virus, but very few recombinants between two genotypes have been reported. FINDINGS:We describe the discovery of an HCV recombinant using a method developed in a United States clinical lab for HCV genotyping that employs sequ...

journal_title：Virology journal

authors： Bhattacharya D,Accola MA,Ansari IH,Striker R,Rehrauer WM

更新日期：2011-10-03 00:00:00

abstract：BACKGROUND:Co-infection of multiple genotypes of human papillomavirus (HPV) is commonly observed among women with abnormal cervical cytology, but how different HPVs interact with each other in the same cell is not clearly understood. A previous study using cultured keratinocytes revealed that genome replication of one ...

journal_title：Virology journal

authors： Mori S,Kusumoto-Matsuo R,Ishii Y,Takeuchi T,Kukimoto I

更新日期：2014-01-24 00:00:00

abstract：:Guards of Cyprian honey bee colonies, Apis mellifera cypria, display a great defensive behaviour against hornets' attacks. The deformed wing virus (DWV) and the kakugo virus (KV) genomes are very similar, but unlike KV, the presence of DWV is not related to honey bees' aggressiveness. This discrepancy is further discu...

journal_title：Virology journal

authors： Rortais A,Tentcheva D,Papachristoforou A,Gauthier L,Arnold G,Colin ME,Bergoin M

更新日期：2006-08-30 00:00:00

abstract：BACKGROUND:Since its first appearance in the USA in 1999, West Nile virus (WNV) has spread in the Western hemisphere and continues to represent an important public health concern. In the absence of effective treatment, there is a medical need for the development of a safe and efficient vaccine. Live attenuated WNV vacc...

journal_title：Virology journal

authors： Spohn G,Jennings GT,Martina BE,Keller I,Beck M,Pumpens P,Osterhaus AD,Bachmann MF

更新日期：2010-07-06 00:00:00

abstract：:Ten potential reference genes were compared for their use in experiments investigating cellular mRNA expression of virus infected cells. Human cell lines were infected with Cytomegalovirus, Human Herpesvirus-6, Camelpox virus, SARS coronavirus or Yellow fever virus. The expression levels of these genes and the viral r...

journal_title：Virology journal

authors： Radonić A,Thulke S,Bae HG,Müller MA,Siegert W,Nitsche A

更新日期：2005-02-10 00:00:00

abstract：BACKGROUND:Influenza A virus evolution in humans is driven at least in part by mutations allowing the virus to escape antibody neutralization. Little is known about the evolution of influenza in birds, a major reservoir of influenza A. METHODS:Neutralizing polyclonal antiserum was raised in chicken against reassortant...

journal_title：Virology journal

authors： Thangavel RR,Reed A,Norcross EW,Dixon SN,Marquart ME,Stray SJ

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:Ticks are implicated as hosts to a wide range of animal and human pathogens. The full range of microbes harbored by ticks has not yet been fully explored. METHODS:As part of a viral surveillance and discovery project in arthropods, we used unbiased high-throughput sequencing to examine viromes of ticks coll...

journal_title：Virology journal

authors： Tokarz R,Sameroff S,Leon MS,Jain K,Lipkin WI

更新日期：2014-02-11 00:00:00

abstract：BACKGROUND:Due to the high prevalence of viral infections having no specific treatment and the constant appearance of resistant viral strains, the development of novel antiviral agents is essential. The aim of this study was to evaluate the antiviral activity against bovine viral diarrhea virus, herpes simplex virus ty...

journal_title：Virology journal

authors： Visintini Jaime MF,Redko F,Muschietti LV,Campos RH,Martino VS,Cavallaro LV

更新日期：2013-07-27 00:00:00

abstract：:Secondary pneumonia due to Staphylococcus aureus (S. aureus) causes significant morbidity and mortality. The aim of the research was designed a novel DNA vaccine encoding the Mycobacterium tuberculosis secreted antigen Ag85A fused with the influenza A virus (IAV) HA2 protein to provide protection against both influenz...

journal_title：Virology journal

authors： Dai J,Pei D,Wang B,Kuang Y,Ren L,Cao K,Zuo B,Shao J,Li S,Jiang Z,Li H,Li M

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:Foot-and-mouth disease (FMD) is an extremely contagious viral disease of cattle, pigs, sheep, goats, and many cloven-hoofed wild animals. FMDV serotypes O and Asia 1 have circulated separately in China during the last fifty years, and eliminating infected animals and vaccination are the main policies to prev...

journal_title：Virology journal

authors： Wu L,Jiang T,Lu ZJ,Yang YM,Sun P,Liang Z,Li D,Fu YF,Cao YM,Liu XT,Liu ZX

更新日期：2011-04-23 00:00:00

abstract：BACKGROUND:Few studies have used quantitative polymerase chain reaction (qPCR) as an approach to measure virus neutralization assay endpoints. Its lack of use may not be surprising considering that sample nucleic acid extraction and purification can be expensive, labor-intensive, and rate-limiting. METHODS:Virus/antib...

journal_title：Virology journal

authors： Varada JC,Teferedegne B,Crim RL,Mdluli T,Audet S,Peden K,Beeler J,Murata H

更新日期：2013-06-15 00:00:00

abstract：BACKGROUND:Controversy remains as to whether antiviral agents contribute to renal dysfunction in patients with chronic hepatitis B virus (HBV) infection. Thus, the aim of study was to analyze the changes in renal function of chronic hepatitis B (CHB) patients in response to anti-HBV therapy and the association with tre...

journal_title：Virology journal

authors： Zhang Y,Zhang WL,Pang XW,Wang LX,Wei X,Huang CX,Bai XF,Han S,Liu LN,Lian JQ

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:Norovirus (NoV) has been recognized as the leading cause of both outbreaks and sporadic cases of acute gastroenteritis in children and adults worldwide. Stool samples collected from outpatients with clinical symptoms of acute gastroenteritis in all age groups at the First People's Hospital in Huzhou, Huzhou,...

journal_title：Virology journal

authors： Han J,Ji L,Shen Y,Wu X,Xu D,Chen L

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:Longitudinal mark-recapture studies of rodents in two sites in the Mbaracayú Biosphere Reserve in the Interior Atlantic Forest of eastern Paraguay have revealed a complex and intriguing pattern of hantaviruses harbored by rodents in this area. Full-length sequencing and phylogenetic analyses were conducted f...

journal_title：Virology journal

authors： Chu YK,Owen RD,Jonsson CB

更新日期：2011-08-12 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in situations where the immune system is immature or compromised. HCMV immediate early (IE) gene expression is stimulated by the virion phosphoprotein pp71, encoded by open reading frame (ORF) UL82, and this transactivation activity...

journal_title：Virology journal

authors： Nicholson IP,Sutherland JS,Chaudry TN,Blewett EL,Barry PA,Nicholl MJ,Preston CM

更新日期：2009-05-27 00:00:00

abstract：BACKGROUND:During October 2010, Egypt reported an outbreak of acute hemorrhagic conjunctivitis (AHC). A total of 1831 cases were reported from three governorates; 1703 cases in El Daqahliya, 92 cases in Port Said, and 36 in Damietta. The purpose of this study was to identify and characterize the causative agent associa...

journal_title：Virology journal

authors： Ayoub EA,Shafik CF,Gaynor AM,Mohareb EW,Amin MA,Yassin AS,El-Refaey S,Genedy M,Kandeel A

更新日期：2013-03-25 00:00:00

abstract：BACKGROUND:Little is known at the molecular level concerning the differences and/or similarities between alcohol and hepatitis C virus induced liver disease. Global transcriptional profiling using oligonucleotide microarrays was therefore performed on liver biopsies from patients with cirrhosis caused by either chronic...

journal_title：Virology journal

authors： Lederer SL,Walters KA,Proll S,Paeper B,Robinzon S,Boix L,Fausto N,Bruix J,Katze MG

更新日期：2006-11-22 00:00:00

abstract：BACKGROUND:Human herpes virus 8 (HHV-8) is the etiologic agent associated with development of classical, AIDS-related, iatrogenic, and endemic Kaposi's sarcoma (KS). Several studies provide strong evidence that HHV-8 can be transmitted by blood transfusion. We evaluated the seroprevalence and potential risk factors of ...

journal_title：Virology journal

authors： Wang X,He B,Zhang Z,Liu T,Wang H,Li X,Zhang Q,Lan K,Lu X,Wen H

更新日期：2010-03-17 00:00:00

abstract：BACKGROUND:To understand the prevalence and characteristics of human cytomegalovirus (HCMV) infection in children in the Weifang area, and to provide information for its prevention and treatment. METHODS:A comprehensive survey was performed from 2009 to 2012 in 7582 children from birth to 6 years of age hospitalized i...

journal_title：Virology journal

authors： Sun X,Liu Z,Wang B,Shi L,Liang R,Li L,Qian D,Song X

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Rapid advances in research on antisense transcripts are gradually changing our comprehension of genomic and gene expression aspects of the Herpesviridae. One such herpesvirus is the human cytomegalovirus (HCMV). Although transcription of the HCMV UL87 gene has not been specifically investigated, cDNA clones ...

journal_title：Virology journal

authors： Ma Y,Wang N,Li M,Gao S,Wang L,Ji Y,Qi Y,He R,Sun Z,Ruan Q

更新日期：2011-11-11 00:00:00

abstract：BACKGROUND:The plateau pika (Ochotona curzoniae) is a small rabbit-like mammal that lives at high altitudes in the Qinghai-Tibet plateau and is in close contact with birds. Following the outbreak of highly pathogenic avian influenza (HPAI) H5N1 during 2005 in the migratory birds of Qinghai Lake, two clades of H5N1 have...

journal_title：Virology journal

authors： Li Y,Xiao H,Huang C,Sun H,Li L,Su J,Ma J,Liu D,Wang H,Liu W,Gao GF,Li X,Yan J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Uukuniemi virus (UUKV) belongs to the Phlebovirus genus in the family Bunyaviridae. As a non-pathogenic virus for humans UUKV has served as a safe model bunyavirus in a number of studies addressing fundamental questions such as organization and regulation of viral genes, genome replication, structure and ass...

journal_title：Virology journal

authors： Katz A,Freiberg AN,Backström V,Schulz AR,Mateos A,Holm L,Pettersson RF,Vaheri A,Flick R,Plyusnin A

更新日期：2010-08-10 00:00:00

abstract：:In September 2012, a novel coronavirus was isolated from a patient in Saudi Arabia who had died of an acute respiratory illness and renal failure. The clinical presentation was reminiscent of the outbreak caused by the SARS-coronavirus (SARS-CoV) exactly ten years ago that resulted in over 8000 cases. Sequence analysi...

journal_title：Virology journal

authors： Khan G

更新日期：2013-02-28 00:00:00

abstract：:We describe an improvement of an earlier reported real-time RT-PCR assay for the detection of enterovirus RNA, based on the 5' exonuclease digestion of a dual-labeled fluorogenic probe by Taq DNA polymerase. A different extraction method, real-time RT-PCR instrument and primer set were evaluated. Our data show that th...

journal_title：Virology journal

authors： Piqueur MA,Verstrepen WA,Bruynseels P,Mertens AH

更新日期：2009-07-07 00:00:00

abstract：BACKGROUND:Polyomaviruses (PyVs) have a wide range of hosts, from humans to fish, and their effects on hosts vary. The differences in the infection characteristics of PyV with respect to the host are assumed to be influenced by the biochemical function of the LT-Ag protein, which is related to the cytopathic effect and...

journal_title：Virology journal

authors： Cho M,Kim H,Son HS

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:Duck circovirus (DuCV) infection in farmed ducks is associated with growth problems or retardation syndromes. Rapid identification of DuCV infected ducks is essential to control DuCV effectively. Therefore, this study aims to develop of an assay for DuCV to be highly specific, sensitive, and simple without a...

journal_title：Virology journal

authors： Xie L,Xie Z,Zhao G,Liu J,Pang Y,Deng X,Xie Z,Fan Q,Luo S

更新日期：2014-04-29 00:00:00

abstract：: Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009. In this study, enteroviruses showed similar seasonal prevalent pattern from summer to fall and age distribution to...

journal_title：Virology journal

authors： Baek K,Yeo S,Lee B,Park K,Song J,Yu J,Rheem I,Kim J,Hwang S,Choi Y,Cheon D,Park J

更新日期：2011-06-13 00:00:00

abstract：BACKGROUND:West Nile virus (WNV) is an emerging zoonotic pathogen which is harmful to human and animal health. Effective vaccination in susceptible hosts should protect against WNV infection and significantly reduce viral transmission between animals and from animals to humans. A versatile vaccine suitable for differen...

journal_title：Virology journal

authors： Wang J,Yang J,Ge J,Hua R,Liu R,Li X,Wang X,Shao Y,Sun E,Wu D,Qin C,Wen Z,Bu Z

更新日期：2016-06-24 00:00:00