Human herpesvirus-8 in northwestern China: epidemiology and characterization among blood donors.

abstract：BACKGROUND:In China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population. METHODS:The data were retrospectively extracted from the hospital medical charts of five centers...

journal_title：Virology journal

authors： Gu J,Yu G,Zhang X,Zhang S,Cai H,Ye C,Yang Y,Li D,Tong Z,Shen H,Chen H,Ding F,Lai X,Liu J,Xu M,Wu W

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Begomoviruses have emerged as serious problem for vegetable and fiber crops in the recent past, frequently in tropical and subtropical region of the world. The association of begomovirus with eggplant yellow mosaic disease is hitherto unknown apart from one report from Thailand. A survey in Nagpur, Central I...

journal_title：Virology journal

authors： Pratap D,Kashikar AR,Mukherjee SK

更新日期：2011-06-16 00:00:00

abstract：BACKGROUND:A novel reassortant H7N9 influenza A virus has crossed the species barrier from poultry to cause human infections in China in 2013 and 2014. Rapid detection of the novel H7N9 virus is important to detect this virus in poultry and reduce the risk of an epidemic in birds or humans. FINDINGS:In this study, a m...

journal_title：Virology journal

authors： Xu X,Bao H,Ma Y,Sun J,Zhao Y,Wang Y,Shi J,Zeng X,Li Y,Wang X,Chen H

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:Ebola viruses (EBOVs) cause severe hemorrhagic fever with a high mortality rate. At present, there are no licensed vaccines or efficient therapies to combat EBOV infection. Previous studies have shown that both humoral and cellular immune responses are crucial for controlling Ebola infection. CD8+ T cells pl...

journal_title：Virology journal

authors： Wu S,Yu T,Song X,Yi S,Hou L,Chen W

更新日期：2012-06-13 00:00:00

abstract：BACKGROUND:Cervical cancer is the fourth most common cancer in women. Early detection and diagnosis play an important role in secondary prevention of cervical cancer. This study aims to provide more information to develop an effective strategy for the prevention and control of cervical cancer in northern China. METHOD...

journal_title：Virology journal

authors： Liu Y,Ang Q,Wu H,Xu J,Chen D,Zhao H,Liu H,Guo X,Gu Y,Qiu H

更新日期：2020-07-13 00:00:00

abstract：:Porcine circoviruses are circular single-stranded DNA viruses that infect swine and wild boars. Two species of porcine circoviruses exist. Porcine circovirus type 1 is non pathogenic contrary to porcine circovirus type 2 which is associated with the disease known as Post-weaning Multisystemic Wasting Syndrome. Porcine...

journal_title：Virology journal

authors： Faurez F,Dory D,Grasland B,Jestin A

更新日期：2009-05-18 00:00:00

abstract：BACKGROUND:Recently, a new subset of CD4(+)T helper cell termed Follicular helper T cells (Tfh), which play a pivotal role in B cell activation and differentiation in lymphoid structures, has been reported to participate in some certain autoimmune diseases. But whether Tfh cells are involved in the pathogenesis of VMC ...

journal_title：Virology journal

authors： Yang F,Mo WH,Tan BP,Wei XM,Wang H

更新日期：2015-02-11 00:00:00

abstract：BACKGROUND:Infection with Chikungunya alphavirus (CHIKV) can cause severe arthralgia and chronic arthritis in humans with persistence of the virus in perivascular macrophages of the synovial membrane by mechanisms largely ill-characterized. FINDINGS:We herein analysed the innate immune response (cytokine and programme...

journal_title：Virology journal

authors： Kumar S,Jaffar-Bandjee MC,Giry C,Connen de Kerillis L,Merits A,Gasque P,Hoarau JJ

更新日期：2012-12-19 00:00:00

abstract：BACKGROUND:The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. METHODS:The safety of LSDV was tested at doses of 104 and 106 plaque forming units in two strains of i...

journal_title：Virology journal

authors： Shen YJ,Shephard E,Douglass N,Johnston N,Adams C,Williamson C,Williamson AL

更新日期：2011-05-30 00:00:00

abstract：BACKGROUND:A variety of interactions between up to three different movement proteins (MPs), the coat protein (CP) and genomic DNA mediate the inter- and intra-cellular movement of geminiviruses in the genus Begomovirus. Although movement of viruses in the genus Mastrevirus is less well characterized, direct interaction...

journal_title：Virology journal

authors： van der Walt E,Palmer KE,Martin DP,Rybicki EP

更新日期：2008-05-20 00:00:00

abstract：:A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV infected patients also contains a heterogeneous population of wild-type and mutant 3a transcripts...

journal_title：Virology journal

authors： Tan TH,Barkham T,Fielding BC,Chou CF,Shen S,Lim SG,Hong W,Tan YJ

更新日期：2005-06-20 00:00:00

abstract：BACKGROUND:Transmissible spongiform encephalopathy (TSE) diseases are known to be zoonotic diseases that can infect different kinds of animals. The transmissibility of TSE, like that of other infectious diseases, shows marked species barrier, either being unable to infect heterologous species or difficult to form trans...

journal_title：Virology journal

authors： Shi Q,Zhang BY,Gao C,Zhang J,Jiang HY,Chen C,Han J,Dong XP

更新日期：2012-03-09 00:00:00

abstract：BACKGROUND:Human Enterovirus 71 (EV71) has emerged as the leading cause of viral encephalitis in children, especially in the Asia-Pacific regions. EV71 vaccine development is of high priority at present, and neutralization antibodies have been documented to play critical roles during in vitro and in vivo protection aga...

journal_title：Virology journal

authors： Li YX,Zhao H,Cao RY,Deng YQ,Han JF,Zhu SY,Ma J,Liu L,Qin ED,Qin CF

更新日期：2014-05-06 00:00:00

abstract：:Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated t...

journal_title：Virology journal

authors： Adlhoch C,Kaiser M,Ellerbrok H,Pauli G

更新日期：2010-07-25 00:00:00

abstract：BACKGROUND:Torque teno virus is a small chronically persisting circular negative ssDNA virus reaching near 100% prevalence. It is reported to be a marker for immune function in immunocompromised patients. The possibility of vertical maternal-fetal transmission remains controversial but incidence rate of TTV DNA in chil...

journal_title：Virology journal

authors： Tyschik EA,Rasskazova AS,Degtyareva AV,Rebrikov DV,Sukhikh GT

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:The major obstacle to cure of HIV type-1 infection is the presence of the HIV reservoir, hidden from the immune system and insensitive to combined antiretroviral therapy (cART). Eradication approaches have been hindered by the difficulty for accurately monitoring its size in vivo, especially in the lymphoid ...

journal_title：Virology journal

authors： Rochat MA,Schlaepfer E,Kuster SP,Li D,Audige A,Ivic S,Fahrny A,Speck RF

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:Human noroviruses (NoVs) are the main cause of gastroenteritis worldwide. The most commonly detected NoV strains belong to the genetically diverse GII.4 genotype, with new pandemic variants emerging periodically. Despite extensive efforts, NoV investigation has been hampered by the lack of an effective in vi...

journal_title：Virology journal

authors： Carmona-Vicente N,Allen DJ,Rodríguez-Díaz J,Iturriza-Gómara M,Buesa J

更新日期：2016-05-21 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are two of the most frequent respiratory pathogens that circulate worldwide. Infection with either virus can lead to hospitalization of young children, immunocompromised people and the elderly.A better understanding of the epidemiologi...

journal_title：Virology journal

authors： Sastre P,Ruiz T,Schildgen O,Schildgen V,Vela C,Rueda P

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:Duck circovirus (DuCV) infection in farmed ducks is associated with growth problems or retardation syndromes. Rapid identification of DuCV infected ducks is essential to control DuCV effectively. Therefore, this study aims to develop of an assay for DuCV to be highly specific, sensitive, and simple without a...

journal_title：Virology journal

authors： Xie L,Xie Z,Zhao G,Liu J,Pang Y,Deng X,Xie Z,Fan Q,Luo S

更新日期：2014-04-29 00:00:00

abstract：BACKGROUND:Viral delivery remains one of the most commonly used techniques today in the field of gene therapy. However, one of the remaining hurdles is the off-targeting effect of viral delivery. To overcome this obstacle, we recently developed a method to incorporate an antibody and a fusogenic molecule (FM) as two di...

journal_title：Virology journal

authors： Lei Y,Joo KI,Zarzar J,Wong C,Wang P

更新日期：2010-02-11 00:00:00

abstract：BACKGROUND:The effect of antiviral therapy in chronic hepatitis B (CHB) on reducing the risk of long-term complications (LTCs) remains unclear so far. To study whether long-term nucleos(t)ide analogues therapy can reduce the risk of long-term complications. METHODS:We searched MEDLINE, EMBASE, OVID, the Cochrane Centr...

journal_title：Virology journal

authors： Zhang QQ,An X,Liu YH,Li SY,Zhong Q,Wang J,Hu HD,Zhang DZ,Ren H,Hu P

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:Tomato yellow leaf curl virus (TYLCV), a monopartite begomovirus (family Geminiviridae) is responsible for heavy yield losses for tomato production around the globe. In Oman at least five distinct begomoviruses cause disease in tomato, including TYLCV. Unusually, TYLCV infections in Oman are sometimes associ...

journal_title：Virology journal

authors： Ammara Ue,Mansoor S,Saeed M,Amin I,Briddon RW,Al-Sadi AM

更新日期：2015-03-04 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV)-associated malignancy remain a main cause of cancer in men and women. Cancer immunotherapy has represented great potential as a new promising cancer therapeutic approach. Here, we report Mesenchymal stem cells (MSCs) as a carrier for the delivery of oncolytic Newcastle disease viru...

journal_title：Virology journal

authors： Keshavarz M,Ebrahimzadeh MS,Miri SM,Dianat-Moghadam H,Ghorbanhosseini SS,Mohebbi SR,Keyvani H,Ghaemi A

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Human astroviruses (HAstVs) are one of the important causes of acute gastroenteritis in children. Currently, eight HAstV genotypes have been identified and all but two (HAstV-6 and HAstV-7) have been fully sequenced. We here sequenced and analyzed the complete genome of a HAstV-6 strain (192-BJ07), which was...

journal_title：Virology journal

authors： Guo L,Gonzalez R,Wang W,Li Y,Paranhos-Baccalà G,Vernet G,Wang J

更新日期：2010-02-08 00:00:00

abstract：BACKGROUND:Reporting new cases of enterovirus (EV)-D68-associated acute flaccid myelitis (AFM) is essential to understand how the virus causes neurological damage and to characterize EV-D68 strains associated with AFM. CASE PRESENTATION:A previously healthy 4-year-old boy presented with sudden weakness and limited mob...

journal_title：Virology journal

authors： Esposito S,Chidini G,Cinnante C,Napolitano L,Giannini A,Terranova L,Niesters H,Principi N,Calderini E

更新日期：2017-01-11 00:00:00

abstract：:The triple-gene-block protein 2 (TGBp2) of Bamboo mosaic virus (BaMV) is a transmembrane protein which was proposed to be involved in viral RNA binding during virus transport. Here, we report on the RNA-binding properties of TGBp2. Using tyrosine fluorescence spectroscopy and UV-crosslinking assays, the TGBp2 solubili...

journal_title：Virology journal

authors： Hsu HT,Tseng YH,Chou YL,Su SH,Hsu YH,Chang BY

更新日期：2009-05-07 00:00:00

abstract：BACKGROUND:With the clinical development of several antiviral intervention strategies for influenza, it becomes crucial to explore viral load shedding in the nasal cavity as a biomarker for treatment success, but also to explore sampling strategies for sensible and reliable virus collection. FINDINGS:In this study, 24...

journal_title：Virology journal

authors： Van Wesenbeeck L,Meeuws H,D'Haese D,Ispas G,Houspie L,Van Ranst M,Stuyver LJ

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until recently, only a few prokaryotic viruses had been described for one of the lin...

journal_title：Virology journal

authors： San Martín C,van Raaij MJ

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV) is associated with 20-40% of Hodgkin's Lymphoma (HL) cases. EBV-encoded latent membrane protein 1 (LMP1) is a well-known oncogenic protein and two C-terminal deletion variants, del30-LMP1 and del69-LMP1, have been described in animal models to be more tumorigenic than the wild-type f...

journal_title：Virology journal

authors： Sueur C,Lupo J,Mas P,Morand P,Boyer V

更新日期：2014-05-19 00:00:00

abstract：BACKGROUND:It is becoming progressively more understandable that genetic variability of viruses is a major challenge in translating the laboratory findings to clinic. Genetic variability is the underlying cause of variant viral proteins which are not targetable by host immunological machinery. METHODS:500 patients wer...

journal_title：Virology journal

authors： Kanwal S,Mahmood T

更新日期：2014-09-30 00:00:00