Molecular characterization and infectivity of a Tomato leaf curl New Delhi virus variant associated with newly emerging yellow mosaic disease of eggplant in India.

abstract：BACKGROUND:HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggested that both host and ...

journal_title：Virology journal

authors： Yamasaki LH,Arcuri HA,Jardim AC,Bittar C,de Carvalho-Mello IM,Rahal P

更新日期：2012-01-12 00:00:00

abstract：:In September 2012, a novel coronavirus was isolated from a patient in Saudi Arabia who had died of an acute respiratory illness and renal failure. The clinical presentation was reminiscent of the outbreak caused by the SARS-coronavirus (SARS-CoV) exactly ten years ago that resulted in over 8000 cases. Sequence analysi...

journal_title：Virology journal

authors： Khan G

更新日期：2013-02-28 00:00:00

abstract：BACKGROUND:The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence in Cameroon, all the major HIV subtypes alongside several circulating recombinant forms (CRFs) and uniqu...

journal_title：Virology journal

authors： Abongwa LE,Nyamache AK,Torimiro JN,Okemo P,Charles F

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:The influenza virus is still one of the most important respiratory risks affecting humans which require effective treatments. In this case, traditional medications are of interest. HESA-A is an active natural biological compound from herbal-marine origin. Previous studies have reported that the therapeutic p...

journal_title：Virology journal

authors： Mehrbod P,Ideris A,Omar AR,Hair-Bejo M,Tan SW,Kheiri MT,Tabatabaian M

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:Previously, we showed that the tetraspanin membrane protein CD63 mediates both early and post-integration stages of the HIV-1 replication cycle. The temporal roles of CD63 were discerned using monoclonal antibodies and small interfering RNAs (siRNAs) to block CD63 function, and determining which of the seque...

journal_title：Virology journal

authors： Li G,Endsley MA,Somasunderam A,Gbota SL,Mbaka MI,Murray JL,Ferguson MR

更新日期：2014-02-08 00:00:00

abstract：BACKGROUND:Hepatitis A virus is an infection of liver; it is hyperendemic in vast areas of the world including India. In most cases it causes an acute self limited illness but rarely fulminant. There is growing concern about change in pattern from asymptomatic childhood infection to an increased incidence of symptomati...

journal_title：Virology journal

authors： Hussain Z,Husain SA,Almajhdi FN,Kar P

更新日期：2011-05-23 00:00:00

abstract：BACKGROUND:Porcine circovirus type-2b (PCV2b) is recognized as the etiological agent of the various clinical manifestations of porcine circovirus-associated disease (PCVAD). Previous studies have demonstrated effectiveness of chimeric PCV1-2 vaccines against PCV2b challenge. In this study, the efficacy of inactivated a...

journal_title：Virology journal

authors： Li J,Yu T,Wang X,Zhou J,Gao R,Zhang F,Gao X,Gao S,Liu X

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Norovirus (NoV) has been recognized as the leading cause of both outbreaks and sporadic cases of acute gastroenteritis in children and adults worldwide. Stool samples collected from outpatients with clinical symptoms of acute gastroenteritis in all age groups at the First People's Hospital in Huzhou, Huzhou,...

journal_title：Virology journal

authors： Han J,Ji L,Shen Y,Wu X,Xu D,Chen L

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:The incidence of dengue, an infectious disease caused by dengue virus (DENV), has dramatically increased around the world in recent decades and is becoming a severe public health threat. However, there is currently no specific treatment for dengue fever, and licensed vaccine against dengue is not available. ...

journal_title：Virology journal

authors： Zhang S,Liang M,Gu W,Li C,Miao F,Wang X,Jin C,Zhang L,Zhang F,Zhang Q,Jiang L,Li M,Li D

更新日期：2011-06-30 00:00:00

abstract：:Phage vB_EcoM_CBA120 (CBA120), isolated against Escherichia coli O157:H7 from a cattle feedlot, is morphologically very similar to the classic phage ViI of Salmonella enterica serovar Typhi. Until recently, little was known genetically or physiologically about the ViI-like phages, and none targeting E. coli have been ...

journal_title：Virology journal

authors： Kutter EM,Skutt-Kakaria K,Blasdel B,El-Shibiny A,Castano A,Bryan D,Kropinski AM,Villegas A,Ackermann HW,Toribio AL,Pickard D,Anany H,Callaway T,Brabban AD

更新日期：2011-09-07 00:00:00

abstract：BACKGROUND:Rapid advances in research on antisense transcripts are gradually changing our comprehension of genomic and gene expression aspects of the Herpesviridae. One such herpesvirus is the human cytomegalovirus (HCMV). Although transcription of the HCMV UL87 gene has not been specifically investigated, cDNA clones ...

journal_title：Virology journal

authors： Ma Y,Wang N,Li M,Gao S,Wang L,Ji Y,Qi Y,He R,Sun Z,Ruan Q

更新日期：2011-11-11 00:00:00

abstract：BACKGROUND:Enteroviruses (EVs) are the leading cause of aseptic meningitis, which is the most frequent central nervous system infection worldwide. We aimed to characterize the EVs involved in an aseptic meningitis outbreak in Korea in 2008. In Korea, Echovirus type 30 (E30) and E6 have been associated with outbreaks an...

journal_title：Virology journal

authors： Kim HJ,Kang B,Hwang S,Hong J,Kim K,Cheon DS

更新日期：2012-02-15 00:00:00

abstract：:A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV infected patients also contains a heterogeneous population of wild-type and mutant 3a transcripts...

journal_title：Virology journal

authors： Tan TH,Barkham T,Fielding BC,Chou CF,Shen S,Lim SG,Hong W,Tan YJ

更新日期：2005-06-20 00:00:00

abstract：BACKGROUND:T4 phage is a model species that has contributed broadly to our understanding of molecular biology. T4 DNA replication and packaging share various mechanisms with human double-stranded DNA viruses such as herpes virus. The literature indicates that T4-like phage genomes have permuted terminal sequences, and ...

journal_title：Virology journal

authors： Jiang X,Jiang H,Li C,Wang S,Mi Z,An X,Chen J,Tong Y

更新日期：2011-04-27 00:00:00

abstract：BACKGROUND:The implementation of phage therapy is re-emerging with the increase in widespread antibiotic-resistant bacteria. METHODS:Staphylococcus phage JD007 was characterized and its complete genome sequence analysed. RESULTS:Staphylococcus phage JD007 was classified as belonging to the Myoviridae family based on ...

journal_title：Virology journal

authors： Cui Z,Feng T,Gu F,Li Q,Dong K,Zhang Y,Zhu Y,Han L,Qin J,Guo X

更新日期：2017-02-08 00:00:00

abstract：BACKGROUND:Endometrial cancer (EC) is one of the most common gynecological malignancies globally. Although progress has been made in surgical and other adjuvant therapies, there is still a great need to develop new approaches to further reduce the incidence and mortality of EC. Oncolytic virotherapy offers a novel prom...

journal_title：Virology journal

authors： Lin Y,Wang W,Wan J,Yang Y,Fu W,Pan D,Cai L,Cheng T,Huang X,Wang Y

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Classical swine fever (CSF) caused by virulent strains of Classical swine fever virus (CSFV) is a haemorrhagic disease of pigs, characterized by disseminated intravascular coagulation, thrombocytopoenia and immunosuppression, and the swine endothelial vascular cell is one of the CSFV target cells. In this re...

journal_title：Virology journal

authors： Tang QH,Zhang YM,Fan L,Tong G,He L,Dai C

更新日期：2010-01-11 00:00:00

abstract：BACKGROUND:LIN28B is involved in multiple cellular developmental processes, tissue inflammatory response and tumourigenesis. The association of LIN28B polymorphisms with hepatitis B virus (HBV) infection remains unknown. METHODS:This study investigated the association of LIN28B rs314277, rs314280, rs369065 and rs77599...

journal_title：Virology journal

authors： Han Q,Sang J,Fan X,Wang X,Zeng L,Zhang X,Zhang K,Li N,Lv Y,Liu Z

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:Varicella (chickenpox) exhibits a characteristic epidemiological pattern which is associated with climate. In general, primary infections in tropical regions are comparatively less frequent among children than in temperate regions. This peculiarity regarding varicella-zoster virus (VZV) infection among certa...

journal_title：Virology journal

authors： Vaughan G,Rodríguez-Castillo A,Cruz-Rivera MY,Ruiz-Tovar K,Ramírez-González JE,Rivera-Osorio P,Fonseca-Coronado S,Carpio-Pedroza JC,Cazares F,Vazquez-Pichardo M,Anaya L,Escobar-Gutiérrez A

更新日期：2011-07-27 00:00:00

abstract：:On 11 March 2020, the World Health Organization (WHO) announced Corona Virus Disease (COVID-19), a disease caused by a pathogen called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pandemic. This ongoing pandemic has now been reported in 215 countries with more than 23 million confirmed cases and mor...

journal_title：Virology journal

authors： Kiros M,Andualem H,Kiros T,Hailemichael W,Getu S,Geteneh A,Alemu D,Abegaz WE

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) bivalent and quadrivalent vaccines have been widely implemented in worldwide organized immunization programs. A nonavalent HPV vaccine is now available in several countries. The objective was to describe the fraction of squamous non-invasive high-grade cervical intraepithelial lesi...

journal_title：Virology journal

authors： Perez S,Iñarrea A,Pérez-Tanoira R,Gil M,López-Díez E,Valenzuela O,Porto M,Alberte-Lista L,Peteiro-Cancelo MA,Treinta A,Carballo R,Reboredo MC,Alvarez-Argüelles ME,Purriños MJ

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and sub-tropical countries, affecting about 50 million people around the world yearly. In Colombia, dengue virus was first detected in 1971 and still remains as a major public health issue. Although four viral serotyp...

journal_title：Virology journal

authors： Méndez JA,Usme-Ciro JA,Domingo C,Rey GJ,Sánchez JA,Tenorio A,Gallego-Gomez JC

更新日期：2012-03-09 00:00:00

abstract：BACKGROUND:It is becoming progressively more understandable that genetic variability of viruses is a major challenge in translating the laboratory findings to clinic. Genetic variability is the underlying cause of variant viral proteins which are not targetable by host immunological machinery. METHODS:500 patients wer...

journal_title：Virology journal

authors： Kanwal S,Mahmood T

更新日期：2014-09-30 00:00:00

abstract：BACKGROUND:Longitudinal mark-recapture studies of rodents in two sites in the Mbaracayú Biosphere Reserve in the Interior Atlantic Forest of eastern Paraguay have revealed a complex and intriguing pattern of hantaviruses harbored by rodents in this area. Full-length sequencing and phylogenetic analyses were conducted f...

journal_title：Virology journal

authors： Chu YK,Owen RD,Jonsson CB

更新日期：2011-08-12 00:00:00

abstract：BACKGROUND:Cell culture adaptation of very virulent infectious bursal disease virus (vvIBDV) was shown to be mainly associated with the VP2 capsid protein residues 253, 279, and 284. The single mutation A284T proved critical for cell culture tropism, but did not confer efficient virus replication, which at least requir...

journal_title：Virology journal

authors： Ben Abdeljelil N,Khabouchi N,Kassar S,Miled K,Boubaker S,Ghram A,Mardassi H

更新日期：2014-11-25 00:00:00

abstract：:In Pakistan, there are estimated 7-9 million carriers of hepatitis B virus (HBV) with a carrier rate of 3-5%. This article reviews the available literature about the prevalence, risk factors, awareness status and genotypes of the HBV in Pakistan by using key words; HBV prevalence, risk factors, awareness status and ge...

journal_title：Virology journal

authors： Ali M,Idrees M,Ali L,Hussain A,Ur Rehman I,Saleem S,Afzal S,Butt S

更新日期：2011-03-06 00:00:00

abstract：BACKGROUND:West Nile virus (WNV) and Usutu virus (USUV), both belonging to the genus Flavivirus, are emerging in Italy as important human and animal pathogens. Migratory birds are involved in the spread of Flaviviruses over long distances, particularly from Africa to Europe. Once introduced, these viruses can be furthe...

journal_title：Virology journal

authors： Grisenti M,Arnoldi D,Rizzolli F,Giacobini M,Bertolotti L,Rizzoli A

更新日期：2013-10-11 00:00:00

abstract：BACKGROUND:Both regulatory T cells (Tregs) and PD-1/PD-L1 pathway were critically involved in HCV viral persistence. However, the association between them was not well investigated. Herein, we aimed to investigate the distributional profiles of Tregs subsets and association between PD-1 expression on these subsets and ...

journal_title：Virology journal

authors： Shen T,Zheng J,Liang H,Xu C,Chen X,Zhang T,Xu Q,Lu F

更新日期：2011-06-07 00:00:00

abstract：BACKGROUND:Porcine epidemic diarrhea virus (PEDV) is the main causative agent of porcine epidemic diarrhea (PED). Since December 2010, a large-scale outbreak of diarrhea has been observed in swine farms in China. Accumulated evidence indicates that this large-scale outbreak of diarrhea were caused by highly virulent PE...

journal_title：Virology journal

authors： Lin H,Chen L,Gao L,Yuan X,Ma Z,Fan H

更新日期：2016-04-22 00:00:00

abstract：BACKGROUND:The aquatic birnavirus infectious pancreatic necrosis virus (IPNV) causes infectious pancreatic necrosis (IPN), a severe disease in farmed salmonid fish. IPNV has a very broad host range and infects many different species of fish as well as molluscs and crustaceans. Investigation of the host reservoir of a v...

journal_title：Virology journal

authors： Ørpetveit I,Küntziger T,Sindre H,Rimstad E,Dannevig BH

更新日期：2012-10-05 00:00:00