Human immunodeficiency virus type 1 ((HIV-1) subtypes in the northwest region, Cameroon.

abstract：BACKGROUND:Otitis media (OM) affects ≥80% of children before the age of three. OM can arise following co-infection with influenza A virus (IAV) and the bacterium Streptococcus pneumoniae. We have previously shown that H3 IAV strains (such as Udorn/72) induced a higher rate of bacterial OM than H1 strains (such as PR8/3...

journal_title：Virology journal

authors： Short KR,Habets MN,Payne J,Reading PC,Diavatopoulos DA,Wijburg OL

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:The UL54 protein of Duck Enteritis Virus (DEV) is a homolog of herpes simplex virus-1 (HSV-1) immediate-early infectious cell protein 27 (ICP27), a multifunctional protein essential for viral infection. Nonetheless, there is little information on the UL54 protein of DEV. METHODS:The UL54 gene was cloned int...

journal_title：Virology journal

authors： Liu C,Cheng A,Wang M,Chen S,Jia R,Zhu D,Liu M,Sun K,Yang Q,Chen X

更新日期：2015-11-25 00:00:00

abstract：BACKGROUND:Human pegivirus-1 (HPgV-1) is a member of the Flaviviridae family whose genomic organization and mode of cellular entry is similar to that of hepatitis C virus (HCV). The E2 glycoprotein of HPgV-1 is the principle mediator in the virus-cell interaction and as such harbors most of HPgV-1's antigenic determina...

journal_title：Virology journal

authors： Vitrenko Y,Kostenko I,Kulebyakina K,Sorochynska K

更新日期：2017-08-31 00:00:00

abstract：BACKGROUND:Longitudinal mark-recapture studies of rodents in two sites in the Mbaracayú Biosphere Reserve in the Interior Atlantic Forest of eastern Paraguay have revealed a complex and intriguing pattern of hantaviruses harbored by rodents in this area. Full-length sequencing and phylogenetic analyses were conducted f...

journal_title：Virology journal

authors： Chu YK,Owen RD,Jonsson CB

更新日期：2011-08-12 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV), human Rhinovirus (HRV) and human Metapneumo Virus (HMPV) are important viral pathogens causing acute respiratory tract infections in the hospitalized patients. Sensitive and accurate detection of RSV, HRV and HMPV is necessary for clinical diagnosis and treatment. RESULTS:...

journal_title：Virology journal

authors： Feng ZS,Zhao L,Wang J,Qiu FZ,Zhao MC,Wang L,Duan SX,Zhang RQ,Chen C,Qi JJ,Fan T,Li GX,Ma XJ

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:Due to the high prevalence of viral infections having no specific treatment and the constant appearance of resistant viral strains, the development of novel antiviral agents is essential. The aim of this study was to evaluate the antiviral activity against bovine viral diarrhea virus, herpes simplex virus ty...

journal_title：Virology journal

authors： Visintini Jaime MF,Redko F,Muschietti LV,Campos RH,Martino VS,Cavallaro LV

更新日期：2013-07-27 00:00:00

abstract：BACKGROUND:Bovine leukemia virus (BLV), which is closely related to human T-cell leukemia virus, is the etiological agent of enzootic bovine leukosis, a disease characterized by a highly prolonged course involving persistent lymphocytosis and B-cell lymphoma. The bovine major histocompatibility complex class II region ...

journal_title：Virology journal

authors： Bai L,Takeshima SN,Sato M,Davis WC,Wada S,Kohara J,Aida Y

更新日期：2019-12-16 00:00:00

abstract：:A previous study has identified two types of recombinant variants of Potato virus Y strain NTN (PVY(NTN)) in China and sequenced the complete genome of the variant PVY(NTN)-HN2. In this study, the complete genome of isolate PVY(NTN)-HN1 was fully sequenced and analyzed. The most striking difference between the two var...

journal_title：Virology journal

authors： Hu X,Nie X,He C,Xiong X

更新日期：2011-05-07 00:00:00

abstract：:Much of the worlds' population is in active or imminent danger from established infectious pathogens, while sporadic and pandemic infections by these and emerging agents threaten everyone. RNA polymerases (RNApol) generate enormous genetic and consequent antigenic heterogeneity permitting both viruses and cellular pat...

journal_title：Virology journal

authors： Sallie R

更新日期：2005-08-22 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in situations where the immune system is immature or compromised. HCMV immediate early (IE) gene expression is stimulated by the virion phosphoprotein pp71, encoded by open reading frame (ORF) UL82, and this transactivation activity...

journal_title：Virology journal

authors： Nicholson IP,Sutherland JS,Chaudry TN,Blewett EL,Barry PA,Nicholl MJ,Preston CM

更新日期：2009-05-27 00:00:00

abstract：BACKGROUND:Emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) in North America, Asia and Europe has caused severe economic loss to the global swine industry. However, the virome of PEDV infected pigs and its effect on disease severity remains unknown. The advancements of sequencing technology have mad...

journal_title：Virology journal

authors： Chen Q,Wang L,Zheng Y,Zhang J,Guo B,Yoon KJ,Gauger PC,Harmon KM,Main RG,Li G

更新日期：2018-05-25 00:00:00

abstract：BACKGROUND:Sequence and structural elements in the 3'-untranslated region (UTR) of Japanese encephalitis virus (JEV) are known to regulate translation and replication. We previously reported an abundant accumulation of small subgenomic flaviviral RNA (sfRNA) which is collinear with the highly conserved regions of the 3...

journal_title：Virology journal

authors： Fan YH,Nadar M,Chen CC,Weng CC,Lin YT,Chang RY

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression that correspond to that specific pathogen. Venezuelan equine encephalitis (VEE) is a mosquito-borne ...

journal_title：Virology journal

authors： Hammamieh R,Barmada M,Ludwig G,Peel S,Koterski N,Jett M

更新日期：2007-08-29 00:00:00

abstract：:Members of the genus Cypovirus (family Reoviridae) are common pathogens of insects. These viruses have linear dsRNA genomes divided into 10-11 segments, which have generally been assumed to be monocistronic. Here, bioinformatic evidence is presented for a short overlapping coding sequence (CDS) in the cypovirus genome...

journal_title：Virology journal

authors： Firth AE,Atkins JF

更新日期：2008-05-20 00:00:00

abstract：BACKGROUND:Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parenterally and occurs both as a primary infection and as reactivation in immunocompromised individuals. C...

journal_title：Virology journal

authors： Burbelo PD,Issa AT,Ching KH,Exner M,Drew WL,Alter HJ,Iadarola MJ

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The plateau pika (Ochotona curzoniae) is a small rabbit-like mammal that lives at high altitudes in the Qinghai-Tibet plateau and is in close contact with birds. Following the outbreak of highly pathogenic avian influenza (HPAI) H5N1 during 2005 in the migratory birds of Qinghai Lake, two clades of H5N1 have...

journal_title：Virology journal

authors： Li Y,Xiao H,Huang C,Sun H,Li L,Su J,Ma J,Liu D,Wang H,Liu W,Gao GF,Li X,Yan J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:The epidemic pattern of respiratory syncytial virus (RSV) is quite different in regions of Europe (biennial epidemics in alternating cycles of approximately 9 and 15 months) than in the Western Hemisphere (annual epidemics). In order to determine if these differences are accounted for by the circulation of d...

journal_title：Virology journal

authors： Mlinaric-Galinovic G,Vojnovic G,Cepin-Bogovic J,Bace A,Bozikov J,Welliver RC,Wahn U,Cebalo L

更新日期：2009-09-07 00:00:00

abstract：:On 11 March 2020, the World Health Organization (WHO) announced Corona Virus Disease (COVID-19), a disease caused by a pathogen called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pandemic. This ongoing pandemic has now been reported in 215 countries with more than 23 million confirmed cases and mor...

journal_title：Virology journal

authors： Kiros M,Andualem H,Kiros T,Hailemichael W,Getu S,Geteneh A,Alemu D,Abegaz WE

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:Classical swine fever (CSF) caused by virulent strains of Classical swine fever virus (CSFV) is a haemorrhagic disease of pigs, characterized by disseminated intravascular coagulation, thrombocytopoenia and immunosuppression, and the swine endothelial vascular cell is one of the CSFV target cells. In this re...

journal_title：Virology journal

authors： Tang QH,Zhang YM,Fan L,Tong G,He L,Dai C

更新日期：2010-01-11 00:00:00

abstract：BACKGROUND:During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until recently, only a few prokaryotic viruses had been described for one of the lin...

journal_title：Virology journal

authors： San Martín C,van Raaij MJ

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:The broad enforcement of active surveillance for bovine spongiform encephalopathy (BSE) in 2000 led to the discovery of previously unnoticed, atypical BSE phenotypes in aged cattle that differed from classical BSE (C-type) in biochemical properties of the pathological prion protein. Depending on the molecula...

journal_title：Virology journal

authors： Tester S,Juillerat V,Doherr MG,Haase B,Polak M,Ehrensperger F,Leeb T,Zurbriggen A,Seuberlich T

更新日期：2009-05-26 00:00:00

abstract：BACKGROUND:Clinical and laboratory studies have indicated that coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) can suppress one another, eliciting a dominant disease phenotype. To assess whether HBV can influence the antiviral effect of treatment on HCV, we performed a meta-analysis to comparativel...

journal_title：Virology journal

authors： Liu JY,Sheng YJ,Hu HD,Zhong Q,Wang J,Tong SW,Zhou Z,Zhang DZ,Hu P,Ren H

更新日期：2012-09-06 00:00:00

abstract：BACKGROUND:The Epstein-Barr virus (EBV) is associated with lymphoid malignancies, including Burkitt's lymphoma (BL), and can transform human B cells in vitro. EBV-harboring cell lines are widely used to investigate lymphocyte transformation and oncogenesis. Qualitative EBV gene expression has been extensively described...

journal_title：Virology journal

authors： Bernasconi M,Berger C,Sigrist JA,Bonanomi A,Sobek J,Niggli FK,Nadal D

更新日期：2006-06-06 00:00:00

abstract：BACKGROUND:Yearly influenza virus mutations potentially affect the performance of molecular assays, if nucleic acid changes involve the sequences in the assay. Because individual patient viral loads depend on variables such as duration of illness, specimen type, age, and immunosuppression, we examined seasonal populati...

journal_title：Virology journal

authors： Rand KH,Pieretti M,Arcenas R,Beal SG,Houck H,Boslet E,Lednicky JA

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Mumps virus (MuV) is a highly infectious paramyxovirus closely related to measles virus (MeV). Despite the availability of a mumps vaccine, outbreaks continue to occur and no treatment options are available. Vitamin A and other naturally occurring retinoids inhibit the replication of MeV in vitro. METHODS:A...

journal_title：Virology journal

authors： Soye KJ,Trottier C,Di Lenardo TZ,Restori KH,Reichman L,Miller WH Jr,Ward BJ

更新日期：2013-11-14 00:00:00

abstract：:Fatal influenza A virus infection is a major threat to public health throughout the world. Lung macrophages and neutrophils have critical roles for both the pathogenesis and viral clearance of fatal viral infections. These are complicated by the interaction of innate immunity and adaptive immunity against viral infect...

journal_title：Virology journal

authors： Lv J,Hua Y,Wang D,Liu A,An J,Li A,Wang Y,Wang X,Jia N,Jiang Q

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain. RESULTS:We have addressed this issue in ...

journal_title：Virology journal

authors： Garg H,Joshi A,Ye C,Shankar P,Manjunath N

更新日期：2011-01-21 00:00:00

abstract：BACKGROUND:Fast, reliable and easy to handle methods are required to facilitate urgently needed point-of-care testing (POCT) in the current coronavirus pandemic. Life-threatening severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread all over the world, infecting more than 33,500,000 people and...

journal_title：Virology journal

authors： Mautner L,Baillie CK,Herold HM,Volkwein W,Guertler P,Eberle U,Ackermann N,Sing A,Pavlovic M,Goerlich O,Busch U,Wassill L,Huber I,Baiker A

更新日期：2020-10-21 00:00:00

abstract：:Six major Hepatitis C virus (HCV) genotypes and hundreds of subtypes have been identified globally. All these genotypes are generally studied for epidemiology, their vaccine development and clinical management. This article comments the frequency distribution of various HCV genotypes circulate in different areas/distr...

journal_title：Virology journal

authors： Ali A,Ahmed H,Idrees M

更新日期：2010-08-26 00:00:00

abstract：:Most viruses take advantage of endocytic pathways to gain entry into host cells and initiate infections. Understanding of virus entry via endocytosis is critically important for the design of antiviral strategies. Virus entry via endocytosis is a complex process involving hundreds of cellular proteins. The entire proc...

journal_title：Virology journal

authors： Barrow E,Nicola AV,Liu J

更新日期：2013-06-05 00:00:00