Viral trans-factor independent replication of human papillomavirus genomes.

abstract：BACKGROUND:Human enterovirus (EV) and parechovirus (HPeV) are significant causes of encephalitis and meningitis in children. The aim of this study was to determine the prevalence, type and viral RNA concentration of EV and HPeV in cerebrospinal fluid (CSF) samples in an unselected cohort of patients <18 years admitted ...

journal_title：Virology journal

authors： Vollbach S,Müller A,Drexler JF,Simon A,Drosten C,Eis-Hübinger AM,Panning M

更新日期：2015-11-25 00:00:00

abstract：BACKGROUND:The effect of antiviral therapy in chronic hepatitis B (CHB) on reducing the risk of long-term complications (LTCs) remains unclear so far. To study whether long-term nucleos(t)ide analogues therapy can reduce the risk of long-term complications. METHODS:We searched MEDLINE, EMBASE, OVID, the Cochrane Centr...

journal_title：Virology journal

authors： Zhang QQ,An X,Liu YH,Li SY,Zhong Q,Wang J,Hu HD,Zhang DZ,Ren H,Hu P

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:Sheeppox (SPP) and goatpox (GTP) caused by sheeppox virus (SPPV) and goatpox virus (GTPV), respectively of the genus Capripoxvirus in the family Poxviridae, are severely afflicting small ruminants' production systems in Africa and Asia. In endemic areas, SPP and GTP are controlled using vaccination with live...

journal_title：Virology journal

authors： Chibssa TR,Grabherr R,Loitsch A,Settypalli TBK,Tuppurainen E,Nwankpa N,Tounkara K,Madani H,Omani A,Diop M,Cattoli G,Diallo A,Lamien CE

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Tembusu virus is a newly emerging flavivirus that caused egg-drop syndrome in ducks in China. TMUV envelope protein is a major structural protein locates at the surface of tembusu virus particle. During tembusu virus infection, envelope protein plays a pivotal role in induction of neutralizing antibody. Howe...

journal_title：Virology journal

authors： Zhao D,Han K,Huang X,Zhang L,Wang H,Liu N,Tian Y,Liu Q,Yang J,Liu Y,Li Y

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:The implementation of phage therapy is re-emerging with the increase in widespread antibiotic-resistant bacteria. METHODS:Staphylococcus phage JD007 was characterized and its complete genome sequence analysed. RESULTS:Staphylococcus phage JD007 was classified as belonging to the Myoviridae family based on ...

journal_title：Virology journal

authors： Cui Z,Feng T,Gu F,Li Q,Dong K,Zhang Y,Zhu Y,Han L,Qin J,Guo X

更新日期：2017-02-08 00:00:00

abstract：BACKGROUND:Dengue has emerged as the most significant of arboviral diseases in the 21st century. It is endemic to >100 tropical and sub-tropical countries around the world placing an estimated 3.6 billion people at risk. It is caused by four genetically similar but antigenically distinct, serotypes of dengue viruses. T...

journal_title：Virology journal

authors： Raut R,Beesetti H,Tyagi P,Khanna I,Jain SK,Jeankumar VU,Yogeeswari P,Sriram D,Swaminathan S

更新日期：2015-02-08 00:00:00

abstract：BACKGROUND:H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China, a crucial stopover or wintering site for migratory wild birds along the East As...

journal_title：Virology journal

authors： Hu C,Li X,Zhu C,Zhou F,Tang W,Wu D,Li Z,Zhou L,Liu J,Wei X,Cui J,Wang T,He G

更新日期：2020-04-29 00:00:00

abstract：UNLABELLED:In the study, a method called "hardening in liquid phase" for preparing chitosan granules with glutaraldehyde as crosslinker and Tween 80 as surfactant and paraffin liquid as dispersant was established. The chitosan granules were light yellow and insoluble in water or oil, but they swelled in acid solution a...

journal_title：Virology journal

authors： Li D

更新日期：2010-06-12 00:00:00

abstract：BACKGROUND:Infection with Chikungunya alphavirus (CHIKV) can cause severe arthralgia and chronic arthritis in humans with persistence of the virus in perivascular macrophages of the synovial membrane by mechanisms largely ill-characterized. FINDINGS:We herein analysed the innate immune response (cytokine and programme...

journal_title：Virology journal

authors： Kumar S,Jaffar-Bandjee MC,Giry C,Connen de Kerillis L,Merits A,Gasque P,Hoarau JJ

更新日期：2012-12-19 00:00:00

abstract：:One coronavirus strain was isolated from brain tissues of ten piglets with evident clinical manifestations of vomiting, diarrhea and dyskinesia in Jilin province in China. Antigenic and genomic characterizations of the virus (isolate PHEV-JLsp09) were based on multiplex PCR and negative staining electron microscopy an...

journal_title：Virology journal

authors： Gao W,Zhao K,Zhao C,Du C,Ren W,Song D,Lu H,Chen K,Li Z,Lan Y,Xie S,He W,Gao F

更新日期：2011-03-21 00:00:00

abstract：BACKGROUND:Echovirus 6 (E6) infections are associated with aseptic meningitis and acute flaccid paralysis (AFP). But some infections, sometimes most of them, are asymptomatic. The mechanism of E6 virulence is unknown. Analyses of the molecular evolution of asymptomatic E6 may help understand why the infections show dif...

journal_title：Virology journal

authors： Sun H,Huang X,Lin K,Huang K,Chu J,Yang Z,Ma S

更新日期：2017-07-25 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are two of the most frequent respiratory pathogens that circulate worldwide. Infection with either virus can lead to hospitalization of young children, immunocompromised people and the elderly.A better understanding of the epidemiologi...

journal_title：Virology journal

authors： Sastre P,Ruiz T,Schildgen O,Schildgen V,Vela C,Rueda P

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:Throughout the history of human influenza pandemics, pigs have been considered the most likely "mixing vessel" for reassortment between human and avian influenza viruses (AIVs). However, the replication efficiencies of influenza viruses from various hosts, as well as the expression of sialic acid (Sia) recep...

journal_title：Virology journal

authors： Van Poucke SG,Nicholls JM,Nauwynck HJ,Van Reeth K

更新日期：2010-02-16 00:00:00

abstract：BACKGROUND:Human Enterovirus 71 (EV71) has emerged as the leading cause of viral encephalitis in children, especially in the Asia-Pacific regions. EV71 vaccine development is of high priority at present, and neutralization antibodies have been documented to play critical roles during in vitro and in vivo protection aga...

journal_title：Virology journal

authors： Li YX,Zhao H,Cao RY,Deng YQ,Han JF,Zhu SY,Ma J,Liu L,Qin ED,Qin CF

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:The plateau pika (Ochotona curzoniae) is a small rabbit-like mammal that lives at high altitudes in the Qinghai-Tibet plateau and is in close contact with birds. Following the outbreak of highly pathogenic avian influenza (HPAI) H5N1 during 2005 in the migratory birds of Qinghai Lake, two clades of H5N1 have...

journal_title：Virology journal

authors： Li Y,Xiao H,Huang C,Sun H,Li L,Su J,Ma J,Liu D,Wang H,Liu W,Gao GF,Li X,Yan J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Persistent infection of human papillomavirus (HPV) types 16 and 18 causes cervical cancer. To better understand immune responses to the prophylactic vaccine, HPV 16/18 L1 virus-like particles (HPV-VLPs), we investigated B cell epitopes of HPV16 L1-derived peptides. METHODS:Sera from mice immunized with HPV-...

journal_title：Virology journal

authors： Fukui A,Matsueda S,Kawano K,Tsuda N,Komatsu N,Shichijo S,Sasada T,Hattori S,Ushijima K,Itoh K,Kamura T

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:Human pegivirus (HPgV) is structurally similar to hepatitis C virus (HCV) and was discovered 20 years ago. Its distribution, natural history and exact rule of this viral group in human hosts remain unclear. Our aim was to determine, by deep next-generation sequencing (NGS), the entire genome sequence of HPgV...

journal_title：Virology journal

authors： Soliman HK,Abouelhoda M,El Rouby MN,Ahmed OS,Esmat G,Hassan ZK,Hafez MM,Mehaney DA,Selvaraju M,Darwish RK,Osman YA,Zekri AN

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:According to international guidelines, HPV DNA tests represent a valid alternative to Pap Test for primary cervical cancer screening, provided that they guarantee balanced clinical sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more severe lesions. The aim of this study was to ...

journal_title：Virology journal

authors： Iacobellis M,Violante C,Notarachille G,Simone A,Scarfì R,Giuffrè G

更新日期：2018-03-20 00:00:00

abstract：BACKGROUND:Acute gastroenteritis caused by bacteria, virus and parasite is an important cause of childhood morbidity and mortality in developing countries. Rotavirus and norovirus have been recognized as the most common pathogens causing acute gastroenteritis among children. However, there is still no valuable data abo...

journal_title：Virology journal

authors： Sai L,Sun J,Shao L,Chen S,Liu H,Ma L

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:Human caliciviruses (HuCV) are emerging enteric pathogens that are a common cause of diarrhea in humans worldwide. Due to the paucity of information on the molecular characterization of HuCV circulating in Mexico, the aim of this work was to investigate the diversity and molecular epidemiology of the HuCV in...

journal_title：Virology journal

authors： Gómez-Santiago F,Ribas-Aparicio RM,García-Lozano H

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) congenital infection is the major viral cause of well-documented birth defects in human. Because CMV is species-specific, the main obstacle to developing animal models for congenital infection is the difference in placental architecture, which preludes virus transmission across the plac...

journal_title：Virology journal

authors： Loh HS,Mohd-Lila MA,Abdul-Rahman SO,Kiew LJ

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:R849 is a neurovirulent γ₁34.5 gene-deficient form of herpes simplex virus type 1 (HSV-1) and has LacZ genes at the deleted sites of the γ₁34.5 gene. HF is a spontaneously occurring, fusogenic HSV-1 strain. The purpose of this work was to generate a virus that has the syncytial character of HF, while preserv...

journal_title：Virology journal

authors： Takaoka H,Takahashi G,Ogawa F,Imai T,Iwai S,Yura Y

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Duck circovirus (DuCV) infection in farmed ducks is associated with growth problems or retardation syndromes. Rapid identification of DuCV infected ducks is essential to control DuCV effectively. Therefore, this study aims to develop of an assay for DuCV to be highly specific, sensitive, and simple without a...

journal_title：Virology journal

authors： Xie L,Xie Z,Zhao G,Liu J,Pang Y,Deng X,Xie Z,Fan Q,Luo S

更新日期：2014-04-29 00:00:00

abstract：:Secondary pneumonia due to Staphylococcus aureus (S. aureus) causes significant morbidity and mortality. The aim of the research was designed a novel DNA vaccine encoding the Mycobacterium tuberculosis secreted antigen Ag85A fused with the influenza A virus (IAV) HA2 protein to provide protection against both influenz...

journal_title：Virology journal

authors： Dai J,Pei D,Wang B,Kuang Y,Ren L,Cao K,Zuo B,Shao J,Li S,Jiang Z,Li H,Li M

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:Influenza viruses are characterized by their highly variable surface proteins HA and NA. The third surface protein M2 is a nearly invariant protein in all Influenza A strains. Despite extensive studies in other animal models, this study is the first to describe the use of recombinant M2 protein and a peptide...

journal_title：Virology journal

authors： Swinkels WJ,Hoeboer J,Sikkema R,Vervelde L,Koets AD

更新日期：2013-06-24 00:00:00

abstract：BACKGROUND:During the pandemic [Influenza A(H1N1)pdm09] period in 2009-2010, an influenza A (Inf-A) virus with H1N2 subtype (designated as A/Eastern India/N-1289/2009) was detected from a 25 years old male from Mizoram (North-eastern India). OBJECTIVE:To characterize full genome of the H1N2 influenza virus. METHODS:F...

journal_title：Virology journal

authors： Mukherjee TR,Agrawal AS,Chakrabarti S,Chawla-Sarkar M

更新日期：2012-10-11 00:00:00

abstract：BACKGROUND:In South Korea, about 20 types of antiretroviral drugs are used in the treatment of patients with human immunodeficiency virus/acquired immune deficiency syndrome. Since 2010, raltegravir, etravirine, and darunavir have been spotlighted as new drugs for highly active antiretroviral therapy (HAART)-experience...

journal_title：Virology journal

authors： Kwon OK,Kim SS,Rhee JE,Kee MK,Park M,Oh HR,Choi JY

更新日期：2015-04-09 00:00:00

abstract：BACKGROUND:The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. METHODS:The safety of LSDV was tested at doses of 104 and 106 plaque forming units in two strains of i...

journal_title：Virology journal

authors： Shen YJ,Shephard E,Douglass N,Johnston N,Adams C,Williamson C,Williamson AL

更新日期：2011-05-30 00:00:00

abstract：:The prevalence of North American orthopoxviruses in nature is unknown and may be more difficult to ascertain due to wide spread use of vaccinia virus recombinant vaccines in the wild. A real time PCR assay was developed to allow for highly sensitive and specific detection of North American orthopoxvirus DNA in animal ...

journal_title：Virology journal

authors： Gallardo-Romero NF,Velasco-Villa A,Weiss SL,Emerson GL,Carroll DS,Hughes CM,Li Y,Karem KL,Damon IK,Olson VA

更新日期：2011-06-20 00:00:00

abstract：BACKGROUND:HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggested that both host and ...

journal_title：Virology journal

authors： Yamasaki LH,Arcuri HA,Jardim AC,Bittar C,de Carvalho-Mello IM,Rahal P

更新日期：2012-01-12 00:00:00