Characterization of hepatitis B virus (HBV) genotypes in patients from Rondônia, Brazil.

abstract：BACKGROUND:Lassa hemorrhagic fever (LHF) is a neglected tropical disease with significant impact on the health care system, society, and economy of Western and Central African nations where it is endemic. With a high rate of infection that may lead to morbidity and mortality, understanding how the virus interacts with ...

journal_title：Virology journal

authors： Branco LM,Grove JN,Moses LM,Goba A,Fullah M,Momoh M,Schoepp RJ,Bausch DG,Garry RF

更新日期：2010-11-09 00:00:00

abstract：BACKGROUND:Human noroviruses (NoVs) are the main cause of gastroenteritis worldwide. The most commonly detected NoV strains belong to the genetically diverse GII.4 genotype, with new pandemic variants emerging periodically. Despite extensive efforts, NoV investigation has been hampered by the lack of an effective in vi...

journal_title：Virology journal

authors： Carmona-Vicente N,Allen DJ,Rodríguez-Díaz J,Iturriza-Gómara M,Buesa J

更新日期：2016-05-21 00:00:00

abstract：:A previous study has identified two types of recombinant variants of Potato virus Y strain NTN (PVY(NTN)) in China and sequenced the complete genome of the variant PVY(NTN)-HN2. In this study, the complete genome of isolate PVY(NTN)-HN1 was fully sequenced and analyzed. The most striking difference between the two var...

journal_title：Virology journal

authors： Hu X,Nie X,He C,Xiong X

更新日期：2011-05-07 00:00:00

abstract：BACKGROUND:Subviral particles of hepatitis B virus (HBV) composed of L protein deletion variants with the 48 N-terminal amino acids of preS joined to the N-terminus of S protein (1-48preS/S) induced broadly neutralizing antibodies after immunization of mice with a Semliki Forest virus vector. A practical limitation for...

journal_title：Virology journal

authors： Niedre-Otomere B,Bogdanova A,Bruvere R,Ose V,Gerlich WH,Pumpens P,Glebe D,Kozlovska T

更新日期：2013-02-25 00:00:00

abstract：BACKGROUND:Double-stranded RNA (dsRNA) and its mimic, polyinosinic acid: polycytidylic acid [Poly (I:C)], are recognized by toll-like receptor 3 (TLR3) and induce interferon (IFN)-β in many cell types. Poly (I:C) is the most potent IFN inducer. In in vivo mouse studies, intraperitoneal injection of Poly (I:C) elicited ...

journal_title：Virology journal

authors： Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-Nuegoonpipat A,Pan Y,Kameoka M,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

更新日期：2012-06-14 00:00:00

abstract：BACKGROUND:The COVID-19 causing coronavirus is an enveloped RNA virus that utilizes an enzyme RNA dependent RNA polymerase for its replication. Favipiravir (FVP) triphosphate, a purine nucleoside analog, inhibits that enzyme. We have conducted this systematic review and meta-analysis on efficacy and safety of the drug ...

journal_title：Virology journal

authors： Shrestha DB,Budhathoki P,Khadka S,Shah PB,Pokharel N,Rashmi P

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:Infectious salmon anemia virus (ISAV) is an important fish pathogen that causes high mortality in farmed Atlantic salmon. The ISAV genome consists of eight single-stranded, negative-sense RNA segments. The six largest segments contain one open reading frame (ORF) each, and encode three polymerase proteins, n...

journal_title：Virology journal

authors： Zhang W,Cai C,Lin L,Tao YJ,Jin M

更新日期：2017-02-15 00:00:00

abstract：:Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear. Recently, some new progress were achieved in molecular character of MDV. Along with the genomic sequencing o...

journal_title：Virology journal

authors： Tian M,Zhao Y,Shi M,Lin Y,Zou N,Liu P,Wen X,Cao S,Huang Y

更新日期：2010-12-23 00:00:00

abstract：BACKGROUND:Porcine circovirus type 2 (PCV2), the causative agent of postweaning multisystemic wasting syndrome (PMWS), is a serious economic problem in the swine industry. Different genotypes (PCV2a, PCV2b and PCV2d) of the virus are present in the clinical cases in China, and it is necessary to elucidate the pathogeni...

journal_title：Virology journal

authors： Guo LJ,Lu YH,Huang LP,Wei YW,Wu HL,Liu CM

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:The gut microbiome is closely associated with the health of the host; although the interaction between the bacterial microbiome and the whole virome has rarely been studied, it is likely of medical importance. Examination of the interactions between the gut bacterial microbiome and virome of rhesus monkey wo...

journal_title：Virology journal

authors： Li H,Li H,Wang J,Guo L,Fan H,Zheng H,Yang Z,Huang X,Chu M,Yang F,He Z,Li N,Yang J,Wu Q,Shi H,Liu L

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1 and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been shown to bind cellular receptors including CD81. In this study, alanine substitutions in E2 were generated within putative CD81 binding regions to define resi...

journal_title：Virology journal

authors： Rothwangl KB,Manicassamy B,Uprichard SL,Rong L

更新日期：2008-03-20 00:00:00

abstract：BACKGROUND/AIM:Hepatitis C virus (HCV) has been the subject of intense research and clinical investigation as its major role in human disease has emerged. HCV circulates in vivo as a complex population of different but closely related viral variants, commonly referred to as a quasispecies. The extent to which recombina...

journal_title：Virology journal

authors： Moreno MP,Casane D,López L,Cristina J

更新日期：2006-10-24 00:00:00

abstract：BACKGROUND:A vaccine against all four dengue virus (DENV) serotypes includes the formulation of one genotype of each serotype. Although genetic similarities among genotypes within a serotype are higher as compared to those among serotypes, differences in the immunogenicity of the included genotypes would be a critical ...

journal_title：Virology journal

authors： Azami NAM,Moi ML,Ami Y,Suzaki Y,Lim CK,Taniguchi S,Saijo M,Takasaki T,Kurane I

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Porcine sapovirus was first identified in the United States in 1980, hitherto, several Asian countries have detected this virus. In 2008, the first outbreak of gastroenteritis in piglets caused by porcine sapovirus in China was reported. The complete genome of the identified SaV strain Ch-sw-sav1 was sequenc...

journal_title：Virology journal

authors： Yang S,Zhang W,Shen Q,Huang F,Wang Y,Zhu J,Cui L,Yang Z,Hua X

更新日期：2009-12-06 00:00:00

abstract：BACKGROUND:The broad enforcement of active surveillance for bovine spongiform encephalopathy (BSE) in 2000 led to the discovery of previously unnoticed, atypical BSE phenotypes in aged cattle that differed from classical BSE (C-type) in biochemical properties of the pathological prion protein. Depending on the molecula...

journal_title：Virology journal

authors： Tester S,Juillerat V,Doherr MG,Haase B,Polak M,Ehrensperger F,Leeb T,Zurbriggen A,Seuberlich T

更新日期：2009-05-26 00:00:00

abstract：BACKGROUND:Host serine proteases are essential for the influenza virus life cycle because the viral haemagglutinin is synthesized as a precursor which requires proteolytic maturation. Therefore, we studied the activity and expression of serine proteases in lungs from mice infected with influenza and evaluated the effec...

journal_title：Virology journal

authors： Bahgat MM,Błazejewska P,Schughart K

更新日期：2011-01-20 00:00:00

abstract：BACKGROUND:Torque teno virus is a small chronically persisting circular negative ssDNA virus reaching near 100% prevalence. It is reported to be a marker for immune function in immunocompromised patients. The possibility of vertical maternal-fetal transmission remains controversial but incidence rate of TTV DNA in chil...

journal_title：Virology journal

authors： Tyschik EA,Rasskazova AS,Degtyareva AV,Rebrikov DV,Sukhikh GT

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Classical swine fever (CSF) caused by virulent strains of Classical swine fever virus (CSFV) is a haemorrhagic disease of pigs, characterized by disseminated intravascular coagulation, thrombocytopoenia and immunosuppression, and the swine endothelial vascular cell is one of the CSFV target cells. In this re...

journal_title：Virology journal

authors： Tang QH,Zhang YM,Fan L,Tong G,He L,Dai C

更新日期：2010-01-11 00:00:00

abstract：BACKGROUND:Multiple studies proved that miRNAs have a causal role in tumorigenesis. Some miRNAs are regulated by epigenetic alterations in their promoter regions and can be activated by chromatin- modifying drugs. METHODS:We treated cervical cancer cells with 5-aza-2'-deoxycytidine and get a microarray analysis. Dysre...

journal_title：Virology journal

authors： Yao T,Rao Q,Liu L,Zheng C,Xie Q,Liang J,Lin Z

更新日期：2013-06-03 00:00:00

abstract：BACKGROUND:With the clinical development of several antiviral intervention strategies for influenza, it becomes crucial to explore viral load shedding in the nasal cavity as a biomarker for treatment success, but also to explore sampling strategies for sensible and reliable virus collection. FINDINGS:In this study, 24...

journal_title：Virology journal

authors： Van Wesenbeeck L,Meeuws H,D'Haese D,Ispas G,Houspie L,Van Ranst M,Stuyver LJ

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:The genus Flavivirus includes several pathogenic agents that cause severe illness in humans. Re-emergence of West Nile virus in Europe and continuous spread of certain flaviviruses such as dengue, yellow fever and Japanese encephalitis viruses represent a global danger to public health. Therefore, a rapid an...

journal_title：Virology journal

authors： Patel P,Landt O,Kaiser M,Faye O,Koppe T,Lass U,Sall AA,Niedrig M

更新日期：2013-02-14 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV)-associated malignancy remain a main cause of cancer in men and women. Cancer immunotherapy has represented great potential as a new promising cancer therapeutic approach. Here, we report Mesenchymal stem cells (MSCs) as a carrier for the delivery of oncolytic Newcastle disease viru...

journal_title：Virology journal

authors： Keshavarz M,Ebrahimzadeh MS,Miri SM,Dianat-Moghadam H,Ghorbanhosseini SS,Mohebbi SR,Keyvani H,Ghaemi A

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence in Cameroon, all the major HIV subtypes alongside several circulating recombinant forms (CRFs) and uniqu...

journal_title：Virology journal

authors： Abongwa LE,Nyamache AK,Torimiro JN,Okemo P,Charles F

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Post-transplant lymphoproliferative disorders (PTLD) are serious complications in lung transplant recipients. No consensus on EBV DNAemia levels predictive of PTLD has been reached. In addition, in many instances EBV DNAemia is determined in patients with suggestive symptoms only. METHODS:The characteristic...

journal_title：Virology journal

authors： Baldanti F,Rognoni V,Cascina A,Oggionni T,Tinelli C,Meloni F

更新日期：2011-09-05 00:00:00

abstract：BACKGROUND:Nuclear factor-kappaB (NF-κB) is an inducible transcription factor that plays a key role in inflammation and immune responses, as well as in the regulation of cell proliferation and survival. Previous studies by our group and others have demonstrated that porcine reproductive and respiratory syndrome virus (...

journal_title：Virology journal

authors： Fang Y,Fang L,Wang Y,Lei Y,Luo R,Wang D,Chen H,Xiao S

更新日期：2012-04-30 00:00:00

abstract：:Retroviral transduction involves integrase-dependent linkage of viral and host DNA that leaves an intermediate that requires post-integration repair (PIR). We and others proposed that PIR hijacks the host cell double-strand DNA break (DSB) repair pathways. Nevertheless, the geometry of retroviral DNA integration diffe...

journal_title：Virology journal

authors： Smith JA,Wang FX,Zhang H,Wu KJ,Williams KJ,Daniel R

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Influenza virus infections are responsible for significant morbidity worldwide and therefore it remains a high priority to develop more broadly protective vaccines. Adjuvation of current seasonal influenza vaccines has the potential to achieve this goal. METHODS:To assess the immune potentiating properties ...

journal_title：Virology journal

authors： Cox F,Saeland E,Baart M,Koldijk M,Tolboom J,Dekking L,Koudstaal W,Lövgren Bengtsson K,Goudsmit J,Radošević K

更新日期：2015-12-08 00:00:00

abstract：BACKGROUND:The influenza RNA dependent RNA polymerase synthesizes viral RNA in the nucleus as functional viral ribonucleoprotein (vRNP) complexes with RNA and nucleoprotein (NP). The N-terminus of NP contains an unconventional nuclear localization signal (NLS) important for initial vRNP nuclear localization but which a...

journal_title：Virology journal

authors： Sanchez A,Guerrero-Juarez CF,Ramirez J,Newcomb LL

更新日期：2014-08-31 00:00:00

abstract：BACKGROUND:Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parenterally and occurs both as a primary infection and as reactivation in immunocompromised individuals. C...

journal_title：Virology journal

authors： Burbelo PD,Issa AT,Ching KH,Exner M,Drew WL,Alter HJ,Iadarola MJ

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Clinical and laboratory studies have indicated that coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) can suppress one another, eliciting a dominant disease phenotype. To assess whether HBV can influence the antiviral effect of treatment on HCV, we performed a meta-analysis to comparativel...

journal_title：Virology journal

authors： Liu JY,Sheng YJ,Hu HD,Zhong Q,Wang J,Tong SW,Zhou Z,Zhang DZ,Hu P,Ren H

更新日期：2012-09-06 00:00:00