Biochemical typing of pathological prion protein in aging cattle with BSE.

abstract：BACKGROUND:Oral malignancy is a major global health problem. Besides the main risk factors of tobacco, smoking and alcohol, infection by human papillomavirus (HPV) and genetic alterations are likely to play an important role in these lesions. The purpose of this study was to compare the efficacy of HC-II assay and PCR ...

journal_title：Virology journal

authors： Chaudhary AK,Pandya S,Mehrotra R,Bharti AC,Singh M,Singh M

更新日期：2010-09-23 00:00:00

abstract：BACKGROUND:Co-circulation of multiple dengue virus serotypes has been reported from many parts of the world including India, however concurrent infection with more than one serotype of dengue viruses in the same individual is rarely documented. An outbreak of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) occ...

journal_title：Virology journal

authors： Bharaj P,Chahar HS,Pandey A,Diddi K,Dar L,Guleria R,Kabra SK,Broor S

更新日期：2008-01-09 00:00:00

abstract：BACKGROUND:Enzootic nasal tumor virus (ENTV) is a betaretrovirus of sheep (ENTV-1) and goats (ENTV-2) associated with neoplastic transformation of epithelial cells of the ethmoid turbinate. Confirmation of the role of ENTV in the pathogenesis of enzootic nasal adenocarcinoma (ENA) has yet to be resolved due to the inab...

journal_title：Virology journal

authors： He Y,Zhang Q,Wang J,Zhou M,Fu M,Xu X

更新日期：2017-07-26 00:00:00

abstract：BACKGROUND:The context and purpose of the study included 1) bacterial expression of viral protein 6 (VP6) of porcine rotavirus (PRV) and generation of rabbit polyclonal antiserum to the VP6 protein; 3) establishment of a discrimination ELISA to distinguish PRV from a panel of other porcine viruses. RESULTS:The VP6 gen...

journal_title：Virology journal

authors： Zhu J,Yang Q,Cao L,Dou X,Zhao J,Zhu W,Ding F,Bu RE,Suo S,Ren Y,Li G,Ren X

更新日期：2013-03-22 00:00:00

abstract：BACKGROUND:Throughout the history of human influenza pandemics, pigs have been considered the most likely "mixing vessel" for reassortment between human and avian influenza viruses (AIVs). However, the replication efficiencies of influenza viruses from various hosts, as well as the expression of sialic acid (Sia) recep...

journal_title：Virology journal

authors： Van Poucke SG,Nicholls JM,Nauwynck HJ,Van Reeth K

更新日期：2010-02-16 00:00:00

abstract：BACKGROUND:Citrus sudden death (CSD), a disease that rapidly kills orange trees, is an emerging threat to the Brazilian citrus industry. Although the causal agent of CSD has not been definitively determined, based on the disease's distribution and symptomatology it is suspected that the agent may be a new strain of Cit...

journal_title：Virology journal

authors： Gomes CP,Nagata T,de Jesus WC Jr,Neto CR,Pappas GJ Jr,Martin DP

更新日期：2008-01-16 00:00:00

abstract：BACKGROUND:To assess the potential effects of telbivudine (LdT) and entecavir (ETV) on renal function in patients with chronic hepatitis B (CHB), we performed a meta-analysis of the relevant data available on these agents to evaluate their effects on the estimated glomerular filtration rate (eGFR) during treatment. ME...

journal_title：Virology journal

authors： Wu X,Cai S,Li Z,Zheng C,Xue X,Zeng J,Peng J

更新日期：2016-04-09 00:00:00

abstract：BACKGROUND:Due to potential advantages, human adenoviral vectors have been evaluated pre-clinically as recombinant vaccine vectors against several cancers and infectious diseases, including human immunodeficiency virus (HIV) infection. The V3 loop of HIV-1 glycoprotein 120 (gp120) contains important neutralizing epitop...

journal_title：Virology journal

authors： Gu L,Krendelchtchikova V,Krendelchtchikov A,Oster RA,Fujihashi K,Matthews QL

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is a major public health problem with more than 170 million cases of chronic infections worldwide. There is no protective vaccine currently available for HCV, therefore the development of novel strategy to prevent chronic infection is important. We reported earlier that a re...

journal_title：Virology journal

authors： Chandra PK,Hazari S,Poat B,Gunduz F,Prabhu R,Liu G,Burioni R,Clementi M,Garry RF,Dash S

更新日期：2010-06-07 00:00:00

abstract：BACKGROUND:Lassa hemorrhagic fever (LHF) is a neglected tropical disease with significant impact on the health care system, society, and economy of Western and Central African nations where it is endemic. With a high rate of infection that may lead to morbidity and mortality, understanding how the virus interacts with ...

journal_title：Virology journal

authors： Branco LM,Grove JN,Moses LM,Goba A,Fullah M,Momoh M,Schoepp RJ,Bausch DG,Garry RF

更新日期：2010-11-09 00:00:00

abstract：BACKGROUND:A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 based lentiviral vector. Bicistronic and tricistronic self-inactivating lentiviral vectors were constr...

journal_title：Virology journal

authors： Chinnasamy D,Milsom MD,Shaffer J,Neuenfeldt J,Shaaban AF,Margison GP,Fairbairn LJ,Chinnasamy N

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Understanding how an organism replicates and assembles a multi-segmented genome with fidelity previously measured at 100% presents a model system for exploring questions involving genome assortment and RNA/protein interactions in general. The virus family Reoviridae, containing nine genera and more than 200 ...

journal_title：Virology journal

authors： Roner MR,Roehr J

更新日期：2006-01-03 00:00:00

abstract：:Porcine circoviruses are circular single-stranded DNA viruses that infect swine and wild boars. Two species of porcine circoviruses exist. Porcine circovirus type 1 is non pathogenic contrary to porcine circovirus type 2 which is associated with the disease known as Post-weaning Multisystemic Wasting Syndrome. Porcine...

journal_title：Virology journal

authors： Faurez F,Dory D,Grasland B,Jestin A

更新日期：2009-05-18 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) congenital infection is the major viral cause of well-documented birth defects in human. Because CMV is species-specific, the main obstacle to developing animal models for congenital infection is the difference in placental architecture, which preludes virus transmission across the plac...

journal_title：Virology journal

authors： Loh HS,Mohd-Lila MA,Abdul-Rahman SO,Kiew LJ

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifier hosts of JEV. Emerging evidence indicates that host microRNAs (miRNAs) play key roles in modulating viral infection and pathogenesis. However, mechanistic studies deli...

journal_title：Virology journal

authors： Yang S,Pei Y,Li X,Zhao S,Zhu M,Zhao A

更新日期：2016-06-21 00:00:00

abstract：BACKGROUND:Tembusu virus is a newly emerging flavivirus that caused egg-drop syndrome in ducks in China. TMUV envelope protein is a major structural protein locates at the surface of tembusu virus particle. During tembusu virus infection, envelope protein plays a pivotal role in induction of neutralizing antibody. Howe...

journal_title：Virology journal

authors： Zhao D,Han K,Huang X,Zhang L,Wang H,Liu N,Tian Y,Liu Q,Yang J,Liu Y,Li Y

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is of growing concern in public health with around 350 million chronically infected individuals worldwide. Although the IFN-alpha/rivabirin is the only approved therapy with 10-30% clinical efficacy, the protective molecular mechanism involved during the treatment is still u...

journal_title：Virology journal

authors： Gómez CE,Vandermeeren AM,García MA,Domingo-Gil E,Esteban M

更新日期：2005-09-12 00:00:00

abstract：BACKGROUND:Since avian-origin H3N2 canine influenza virus (CIV) was first identified in South Korea in 2008, the novel influenza virus has been reported in several countries in Asia. Reverse zoonotic transmission of pandemic H1N1 (2009) influenza virus (pH1N1) has been observed in a broad range of animal species. Viral...

journal_title：Virology journal

authors： Na W,Lyoo KS,Song EJ,Hong M,Yeom M,Moon H,Kang BK,Kim DJ,Kim JK,Song D

更新日期：2015-09-04 00:00:00

abstract：BACKGROUND:The membrane topology and molecular mechanisms for endoplasmic reticulum (ER) localization of classical swine fever virus (CSFV) non-structural 2 (NS2) protien is unclear. We attempted to elucidate the subcellular localization, and the molecular mechanisms responsible for the localization of this protein in ...

journal_title：Virology journal

authors： Guo KK,Tang QH,Zhang YM,Kang K,He L

更新日期：2011-05-18 00:00:00

abstract：:Phage vB_EcoM_CBA120 (CBA120), isolated against Escherichia coli O157:H7 from a cattle feedlot, is morphologically very similar to the classic phage ViI of Salmonella enterica serovar Typhi. Until recently, little was known genetically or physiologically about the ViI-like phages, and none targeting E. coli have been ...

journal_title：Virology journal

authors： Kutter EM,Skutt-Kakaria K,Blasdel B,El-Shibiny A,Castano A,Bryan D,Kropinski AM,Villegas A,Ackermann HW,Toribio AL,Pickard D,Anany H,Callaway T,Brabban AD

更新日期：2011-09-07 00:00:00

abstract：BACKGROUND:In South Korea, about 20 types of antiretroviral drugs are used in the treatment of patients with human immunodeficiency virus/acquired immune deficiency syndrome. Since 2010, raltegravir, etravirine, and darunavir have been spotlighted as new drugs for highly active antiretroviral therapy (HAART)-experience...

journal_title：Virology journal

authors： Kwon OK,Kim SS,Rhee JE,Kee MK,Park M,Oh HR,Choi JY

更新日期：2015-04-09 00:00:00

abstract：BACKGROUND:The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). The HIV-1 Vpu protein is an oligomeric integral membrane protein essential for particle release, viral load and CD4 degradation. In silico models show Vpu to form penta...

journal_title：Virology journal

authors： Hussain A,Das SR,Tanwar C,Jameel S

更新日期：2007-08-29 00:00:00

abstract：:Retroviral transduction involves integrase-dependent linkage of viral and host DNA that leaves an intermediate that requires post-integration repair (PIR). We and others proposed that PIR hijacks the host cell double-strand DNA break (DSB) repair pathways. Nevertheless, the geometry of retroviral DNA integration diffe...

journal_title：Virology journal

authors： Smith JA,Wang FX,Zhang H,Wu KJ,Williams KJ,Daniel R

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in situations where the immune system is immature or compromised. HCMV immediate early (IE) gene expression is stimulated by the virion phosphoprotein pp71, encoded by open reading frame (ORF) UL82, and this transactivation activity...

journal_title：Virology journal

authors： Nicholson IP,Sutherland JS,Chaudry TN,Blewett EL,Barry PA,Nicholl MJ,Preston CM

更新日期：2009-05-27 00:00:00

abstract：BACKGROUND:H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population. Vaccination is the best strategy to control H5N1 HPAIV infection in poultry and transmission to human population. The aim of this study is to identif...

journal_title：Virology journal

authors： Zhang W,Tu J,Zhao Z,Chen H,Jin M

更新日期：2012-05-23 00:00:00

abstract：:Hepatitis E virus (HEV) is a zoonotic pathogen of which several species of animal were reported as reservoirs. Swine stands out as the major reservoir for HEV infection in humans, as suggested by the close genetic relationship of swine and human virus and cross-species infection of HEV. Up to now, the mechanism of cro...

journal_title：Virology journal

authors： Zhang W,Hua X,Shen Q,Yang S,Yin H,Cui L

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:Highly-pathogenic avian influenza (HPAI) H5N1 and Newcastle disease (ND) viruses are the two most important poultry viruses in the world, with the ability to cause classic central nervous system dysfunction in poultry and migratory birds. To elucidate the mechanisms of neurovirulence caused by these viruses,...

journal_title：Virology journal

authors： Balasubramaniam VR,Wai TH,Omar AR,Othman I,Hassan SS

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:With the clinical development of several antiviral intervention strategies for influenza, it becomes crucial to explore viral load shedding in the nasal cavity as a biomarker for treatment success, but also to explore sampling strategies for sensible and reliable virus collection. FINDINGS:In this study, 24...

journal_title：Virology journal

authors： Van Wesenbeeck L,Meeuws H,D'Haese D,Ispas G,Houspie L,Van Ranst M,Stuyver LJ

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:Nonstructural glycoprotein 4 (NSP4) encoded by rotavirus is the only viral protein currently believed to function as an enterotoxin. NSP4 is synthesized as an intracellular transmembrane glycoprotein and as such is essential for virus assembly. Infection of polarized Caco-2 cells with rotavirus also results ...

journal_title：Virology journal

authors： Didsbury A,Wang C,Verdon D,Sewell MA,McIntosh JD,Taylor JA

更新日期：2011-12-20 00:00:00

abstract：:Six major Hepatitis C virus (HCV) genotypes and hundreds of subtypes have been identified globally. All these genotypes are generally studied for epidemiology, their vaccine development and clinical management. This article comments the frequency distribution of various HCV genotypes circulate in different areas/distr...

journal_title：Virology journal

authors： Ali A,Ahmed H,Idrees M

更新日期：2010-08-26 00:00:00