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  • Usefulness of automated fragmented red blood cell percentage in the diagnosis of paediatric haemolytic uraemic syndrome.

    abstract:INTRODUCTION:Presence of schistocytes in peripheral blood smear supporting haemolysis is important for diagnosis and decision-making in paediatric haemolytic uraemic syndrome (HUS). High observer dependency and requirement of expertise for peripheral smear evaluation propels us to think of other modalities to overcome ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13324

    authors: Govindarajan S,Bhatia P,Dawman L,Tiewsoh K

    更新日期:2021-02-01 00:00:00

  • The HemoScreen hematology point-of-care device is suitable for rapid evaluation of acute leukemia patients.

    abstract:BACKGROUND:Hematological patients, receiving intensive chemotherapy (predominantly acute leukemia patients), have repeated postchemotherapy periods with severe bone marrow suppression. As a result, these patients require regular monitoring of the complete blood counts (CBC) for optimal patient care. To reduce the strai...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13330

    authors: Kristian Kur D,Thøgersen D,Kjeldsen L,Friis-Hansen L

    更新日期:2021-02-01 00:00:00

  • ADAMTS13 activity to von Willebrand factor antigen ratio predicts acute kidney injury in patients with COVID-19: Evidence of SARS-CoV-2 induced secondary thrombotic microangiopathy.

    abstract:INTRODUCTION:Severe COVID-19 is often compounded by a prothrombotic state that is associated with poor outcomes. In this investigation, we aimed to evaluate ADAMTS13 activity, von Willebrand factor level (VWF:Ag), and the corresponding ADAMTS13 activity/VWF:Ag ratio, in patients with COVID-19 and for associations with ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13415

    authors: Henry BM,Benoit SW,de Oliveira MHS,Lippi G,Favaloro EJ,Benoit JL

    更新日期:2020-12-03 00:00:00

  • Multicentric evaluation of the new HemosIL Acustar® chemiluminescence ADAMTS13 activity assay.

    abstract:INTRODUCTION:Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening thrombotic microangiopathy (TMA) characterized by the severe deficiency of ADAMTS13 activity (<10%). Rapid ADAMTS13 testing is crucial for early diagnosis and optimal management of TTP patients and other TMAs. The objective of this study ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13414

    authors: Pascual C,Nieto JM,Fidalgo T,Seguí IG,Díaz-Ricart M,Docampo MF,Del Rio J,Salinas R

    更新日期:2020-12-02 00:00:00

  • Use of Sysmex XN-10 red blood cell parameters for screening of hereditary red blood cell diseases and iron deficiency anaemia.

    abstract:INTRODUCTION:In daily practice in haematology laboratories, red blood cell (RBC) abnormalities are frequent and their management is a real challenge. The aim of this study is to establish a "decision tree" using RBC and reticulocyte parameters from the SYSMEX XN-10 analyser to distinguish between patients with a heredi...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13278

    authors: Nivaggioni V,Bouriche L,Coito S,Le Floch AS,Ibrahim-Kosta M,Leonnet C,Arnoux I,Loosveld M

    更新日期:2020-12-01 00:00:00

  • Clinical and hematological characteristics of 88 patients with COVID-19.

    abstract:INTRODUCTION:To retrospectively analyze epidemiological, clinical and hematological characteristics of COVID-19 patients. METHODS:The demographic, symptoms, and physiological parameters of 88 patients were collected and analyzed. The performance of complete blood count (CBC) indexes for monitoring and predicting the s...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13291

    authors: Zhang H,Cao X,Kong M,Mao X,Huang L,He P,Pan S,Li J,Lu Z

    更新日期:2020-12-01 00:00:00

  • International Council for Standardization in Haematology (ICSH) laboratory guidance for the evaluation of haemostasis analyser-reagent test systems. Part 1: Instrument-specific issues and commonly used coagulation screening tests.

    abstract::Before a new method is used for clinical testing, it is essential that it is evaluated for suitability for its intended purpose. This document gives guidance for the performance of verification, validation and implementation processes required by regulatory and accreditation bodies. It covers the planning and executio...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,评审

    doi:10.1111/ijlh.13411

    authors: Gardiner C,Coleman R,de Maat MPM,Dorgalaleh A,Echenagucia M,Gosselin RC,Ieko M,Kitchen S

    更新日期:2020-11-29 00:00:00

  • Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID-19.

    abstract:INTRODUCTION:Early diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) abnormalities related to COVID-19 at disease onset. METHODS:Baseline ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13395

    authors: Naoum FA,Ruiz ALZ,Martin FHO,Brito THG,Hassem V,Oliveira MGL

    更新日期:2020-11-15 00:00:00

  • The hematology laboratory's response to the COVID-19 pandemic: A scoping review.

    abstract::The ongoing COVID-19 pandemic has had a profound worldwide impact on the laboratory hematology community. Nevertheless, the pace of COVID-19 hematology-related research has continued to accelerate and has established the role of laboratory hematology data for many purposes including disease prognosis and outcome. The ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,评审

    doi:10.1111/ijlh.13381

    authors: Bell R,Zini G,d'Onofrio G,Rogers HJ,Lee YS,Frater JL

    更新日期:2020-11-12 00:00:00

  • Assessing maternal clotting function with novel global coagulation assays: A prospective pilot study.

    abstract:INTRODUCTION:Women are at higher risk of venous thromboembolism (VTE) during pregnancy and the puerperium. Global coagulation assays (GCAs), including thromboelastography (TEG), thrombin generation using the calibrated automated thrombogram (CAT) and fibrin generation using the overall haemostatic potential assay (OHP)...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13389

    authors: O'Keefe D,Lim HY,Tham J,Ho P,Hui L

    更新日期:2020-11-10 00:00:00

  • Evaluation of automated capillary complete blood counts for routine clinical decision making in a large cohort of hematological patients, using Mindray BC-3000 Plus Auto and Sysmex XE-5000 hematology analyzers.

    abstract:INTRODUCTION:Venous blood (VB) sampling for complete blood count (CBC) via venipuncture is the basic method for the daily evaluation of hematological patients. However, several issues during this process, such as venipuncture difficulty and repetitive attempts, may cause pain, phlebitis, hematomas, inadequate sampling,...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13237

    authors: Oudatzis G,Tsagarakis NJ,Paterakis G,Vasileiou P,Xenou E,Maraki P,Pangrati T,Angelopoulou MK,Vassilakopoulos TP,Konstantopoulos K

    更新日期:2020-10-01 00:00:00

  • Establishment of reference intervals for pediatric complete capillary blood counts: A multicenter study in Beijing.

    abstract:INTRODUCTION:Clinical reference intervals represent the normal range of clinical parameters for distinguishing healthy and sick individuals, and they show some variation among different populations. Many reference intervals are still lacking for the pediatric population in China. Thus, the aim of this study was to esta...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13150

    authors: Sun Q,Yue Y,Tian Y,Wang Q

    更新日期:2020-10-01 00:00:00

  • Evaluation of the HemoCue WBC DIFF in leukopenic patient samples.

    abstract:BACKGROUND:White blood cell (WBC) counts are used to monitor bone marrow function and to screen for infections. The HemoCue WBC DIFF Point-Of-Care (POC) instrument classifies WBCs through cell image recognition. To evaluate its suitability for monitoring cancer patients, we examined its performance in samples from pati...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13158

    authors: Kur DK,Agersnap N,Holländer NH,Pedersen OBV,Friis-Hansen L

    更新日期:2020-06-01 00:00:00

  • Upregulation of long noncoding RNA Lnc-IRF2-3 and Lnc-ZNF667-AS1 is associated with poor survival in B-chronic lymphocytic leukemia.

    abstract:BACKGROUND:Lnc-IRF2-3 and Lnc-ZNF667-AS1 were recently studied as a positive biomarker for many tumor cells. However, experimental studies found that they are associated with worse outcomes in B-CLL. METHODS:A prospective case study was conducted on 135 B-CLL patients that were compared to thirty healthy controls. The...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13167

    authors: El-Khazragy N,Esmaiel MA,Mohamed MM,Hassan NS

    更新日期:2020-06-01 00:00:00

  • Chronic active Epstein-Barr virus infection: A heterogeneous entity requiring a high index of suspicion for diagnosis.

    abstract::Chronic active Epstein-Barr virus infection of T- and NK-cell type, systemic form, is a rare entity within the spectrum of EBV-driven T- and NK-cell lymphoproliferative disorders. Established diagnostic criteria and a characteristic clinical course help to differentiate it from other closely related EBV-positive neopl...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,评审

    doi:10.1111/ijlh.13199

    authors: Ondrejka SL,Hsi ED

    更新日期:2020-06-01 00:00:00

  • Flow cytometry in the diagnosis of mature B-cell lymphoproliferative disorders.

    abstract::B-lineage lymphoproliferative disorders (LPD) are rather frequent diseases, associated with specific clinical or biological features but also sometimes of fortuitous discovery. Multiparameter flow cytometry plays a major role for a rapid diagnostic indication, on peripheral blood or bone marrow samples in most instanc...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,评审

    doi:10.1111/ijlh.13170

    authors: Debord C,Wuillème S,Eveillard M,Theisen O,Godon C,Le Bris Y,Béné MC

    更新日期:2020-06-01 00:00:00

  • Real-world assay variability between laboratories in monitoring of recombinant factor IX Fc fusion protein activity in plasma samples.

    abstract:INTRODUCTION:Monitoring of factor IX (FIX) replacement therapy in haemophilia B relies on accurate coagulation assays. However, considerable interlaboratory variability has been reported for one-stage clotting (OSC) assays. This study aimed to evaluate the real-world, interlaboratory variability of routine FIX activity...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ijlh.13189

    authors: Sommer JM,Sadeghi-Khomami A,Barnowski C,Wikén M,Willemze AJ

    更新日期:2020-06-01 00:00:00

  • DOAC plasma levels measured by chromogenic anti-Xa assays and HPLC-UV in apixaban- and rivaroxaban-treated patients from the START-Register.

    abstract:INTRODUCTION:To measure direct factor Xa inhibitor (apixaban, edoxaban, rivaroxaban) concentrations, dedicated chromogenic anti-Xa assays are recommended as suitable methods to provide rapid drug quantification. Moreover, the high-performance liquid chromatography with ultraviolet detection (HPLC-UV) is reported as a r...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13159

    authors: Cini M,Legnani C,Padrini R,Cosmi B,Dellanoce C,De Rosa G,Marcucci R,Pengo V,Poli D,Testa S,Palareti G

    更新日期:2020-04-01 00:00:00

  • Hemostasis critical values among Iranian clinical laboratories "National Survey of 157 Clinical Laboratories".

    abstract:BACKGROUND:Immediate reporting of critical values or test results significantly outside the normal range has a growing role in the management of patients, especially in life-threatening conditions. Due to the lack of international consensus, diverse approaches are used for determination of thresholds, reporting, docume...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13109

    authors: Dorgalaleh A,Shiravand Y,Dabbagh A,Tabibian S,Hosseini MS,Mansouri Tourghabeh H,Rashidpanah J,Narouei F,Shams M,Gholami MS,Saneei Moghaddam E,Shahreki H

    更新日期:2019-12-01 00:00:00

  • A hierarchical approach in the diagnostic workflow of chronic myelomonocytic leukemia: Pivotal role of the "Mono-dysplasia-score" combined with flow cytometric quantification of monocyte subsets.

    abstract:INTRODUCTION:Monocytosis is a frequent trigger for blood smear review in a routine hematology laboratory whereas chronic myelomonocytic leukemia (CMML) is infrequent and arises mostly in elderly patients. In order to define the best workflow for monocytosis, we studied three diagnostic approaches: the classical morphol...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13115

    authors: Zhu J,Sourdeau E,Aubert H,Clauser S,Maillon A,Capron C,Jondeau K,Ronez E,Schillinger F,Garnache-Ottou F,Cornet E,Bardet V

    更新日期:2019-12-01 00:00:00

  • Performance evaluation of a new Stago® automated haemostasis analyser: The STA R Max® 2.

    abstract:INTRODUCTION:The STA R Max® 2 is a new coagulation analyser developed by Diagnostica Stago, able to perform clotting, chromogenic and immuno-turbidimetric tests. A pre-analytical module build into the cap-piercing needle performs the sample integrity verification (sample tube filling and measurement of haemolysis, icte...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13100

    authors: Cupaiolo R,Govaerts D,Blauwaert M,Cauchie P

    更新日期:2019-12-01 00:00:00

  • Low expression of TET2 gene in pediatric acute lymphoblastic leukemia is associated with poor clinical outcome.

    abstract:INTRODUCTION:TET2, a member of the Ten-Eleven translocation gene family, catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine in DNA. Low expression of TET2 has been reported as a prognostic factor for several types of malignancies in adult patients. However, there have been few data on the effect of...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13099

    authors: Zhang P,Weng WW,Chen P,Zhang Y,Ruan JF,Ba DD,Xu WQ,Tang YM

    更新日期:2019-10-01 00:00:00

  • The applicability of multiparameter flow cytometry for the detection of minimal residual disease using different-from-normal panels to predict relapse in patients with acute myeloid leukemia after allogeneic transplantation.

    abstract:BACKGROUND:The MRD status detected using multiparameter flow cytometry (MFC) before allogeneic hematopoietic stem cell transplantation (allo-HSCT) has crucial prognostic value for patients with acute myeloid leukemia (AML) in morphologic complete remission (CR). We designed a novel panel of antibodies to identify aberr...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13070

    authors: Wang Z,Guo M,Zhang Y,Xu S,Cheng H,Wu J,Zhang W,Hu X,Yang J,Wang J,Tang G

    更新日期:2019-10-01 00:00:00

  • Clinical performance evaluation of the new hematology analyzer Mindray BC-6000.

    abstract:INTRODUCTION:With the progression of blood analysis technology, hematology analyzers become more complex and diverse. How to choose a superb instrument is a challenge for the laboratories. In the essay, we studied whether the newest BC-6000 hematology analyzer meets the needs of a clinical hematology laboratory. METHO...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13075

    authors: Shen Y,Cao J,Zhou Z,Wang Y,Shen Y,He J

    更新日期:2019-10-01 00:00:00

  • Establishment of reference intervals for complete blood count parameters in venous blood for children in the Xiamen area, China.

    abstract:OBJECTIVES:To observe changes in the complete blood count (CBC) venous blood parameters of healthy children and establish appropriate reference intervals (RIs). METHODS:Overall, 4066 healthy children were selected and divided into four groups: infants, toddlers, preschool-age children and school-age children. Venous b...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13095

    authors: Li J,Zhang H,Huang X,Zhang J,Wu X

    更新日期:2019-10-01 00:00:00

  • Paediatric reference intervals for common coagulation assays in Chinese children as performed on the STA-R coagulation analyzer.

    abstract:INTRODUCTION:In order to correctly manage the paediatric patients affected with haemostatic disorders, age-appropriate reference intervals should be used. The purpose of this study was to establish age-specific reference intervals for prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (aPT...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13098

    authors: Liu J,Dai Y,Yuan E,Li Y,Wang Q,Wang L,Su Y

    更新日期:2019-10-01 00:00:00

  • Evaluation of an automated algorithm for interpretation of lupus anticoagulant testing.

    abstract:INTRODUCTION:Lupus anticoagulant (LAC) testing is a multistep procedure including screening, mixing, and confirmation tests. STA Coag Expert is a software module for STA R Max and STA Compact Max analyzers which includes an on-demand LAC algorithm, based on ISTH guidelines, for automatic interpretation, calculation, an...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.13001

    authors: Florin L,Desloovere M,Devreese KMJ

    更新日期:2019-06-01 00:00:00

  • Optimal wavelength for the clot waveform analysis: Determination of the best resolution with minimal interference of the reagents.

    abstract:INTRODUCTION:Clot waveform analysis (CWA), a new methodology to assess coagulation process, can be usefully applied in various clinical settings. However, its clinical use is limited mainly because of the absence of standardization. No consensus exists regarding the wavelengths at which CWA has to be performed what is ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12975

    authors: Evrard J,Siriez R,Morimont L,Thémans P,Laloy J,Bouvy C,Gheldof D,Mullier F,Dogné JM,Douxfils J

    更新日期:2019-06-01 00:00:00

  • Flow cytometry data analysis: Recent tools and algorithms.

    abstract::Flow cytometry (FCM) allows scientists to rapidly quantify up to 50 parameters for millions of cells per sample. The bottleneck in the application of the technology is data analysis, and the high number of parameters measured by the current generation of instruments requires the use of advanced computational algorithm...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,评审

    doi:10.1111/ijlh.13016

    authors: Montante S,Brinkman RR

    更新日期:2019-05-01 00:00:00

  • A level-headed approach to measuring direct oral anticoagulants: A 2-year retrospective analysis of DOAC levels from a tertiary UK centre.

    abstract:INTRODUCTION:Direct oral anticoagulants (DOAC) are commonly prescribed and measuring drug levels may be useful in a number of contexts. However, data on DOAC level measurement and their clinical utility in real-world studies are limited. METHODS:We carried out a 2-year retrospective cohort study of DOAC levels measure...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12944

    authors: Denny NDR,Keighley L,Siganporia Z,Thachil J,Nash MJ

    更新日期:2019-04-01 00:00:00

  • Clotting and chromogenic factor VIII assay variability in post-infusion and spiked samples containing full-length recombinant FVIII or recombinant factor VIII Fc fusion protein (rFVIIIFc).

    abstract:INTRODUCTION:Variability in FVIII measurement is a recognized problem. There are limited data for samples containing recombinant Factor VIII Fc fusion protein (rFVIIIFc). Many studies use samples for which factor concentrate has been spiked into FVIII deficient plasma in vitro. This approach requires validation. AIM/M...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12940

    authors: Kitchen S,Jennings I,Makris M,Kitchen DP,Woods TAL,Walker ID

    更新日期:2019-04-01 00:00:00

  • Lack of harmonization in high fluorescent cell automated counts with body fluids mode in ascitic, pleural, synovial, and cerebrospinal fluids.

    abstract:INTRODUCTION:Cellular analysis in body fluids (BFs) provides important diagnostic information in various pathological settings. This study was hence aimed at comparing automated cell count obtained with Mindray BC-6800 (BC-BF) vs Sysmex XN-series (XN-BF) and evaluating other quantitative and qualitative information pro...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12968

    authors: Buoro S,Seghezzi M,Dominoni P,Moioli V,Manenti B,Previtali G,Ottomano C,Lippi G

    更新日期:2019-04-01 00:00:00

  • How I investigate Eosinophilia.

    abstract::Eosinophilia is typically secondary, that is, reactive, in nature and is associated with a wide variety of neoplastic and non-neoplastic disorders. Clonal eosinophilia is also seen in a wide variety of hematopoietic neoplasms, and sub-classification can be diagnostically challenging. A proper evaluation of persistent ...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章,评审

    doi:10.1111/ijlh.12955

    authors: Larsen RL,Savage NM

    更新日期:2019-04-01 00:00:00

  • Use of a capillary specimen in the laboratory to verify a point-of-care international normalized ratio: Avoidance of a venipuncture in a pediatric setting.

    abstract:INTRODUCTION:Point-of-care (POC) international normalized ratio (INR) values above an institutional cutoff are confirmed in the laboratory using a gold standard venous specimen. This can be problematic in a pediatric setting. METHOD:In this study, 449 consecutive POC INR results were compared to an INR performed in th...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12920

    authors: Williams VK

    更新日期:2019-02-01 00:00:00

  • Live remote digital microscopy in peripheral blood smear evaluation: Intraobserver concordance and experience.

    abstract:INTRODUCTION:Peripheral blood smear (PBS) review is a routine laboratory test which requires pathologist's interpretation when abnormal indices, atypical cells, or critical findings are identified. Real-time remote digital microscopy (DM) can potentially facilitate rapid review when an on-site pathologist is not availa...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12914

    authors: Haninger DM,Nassiri M,Settembre ED,Zhang S,Zhou J

    更新日期:2018-12-01 00:00:00

  • The clinical utility of new reticulocyte and erythrocyte parameters on the Sysmex XN 9000 for iron deficiency in pregnant patients.

    abstract:INTRODUCTION:Iron deficiency (ID) is a major cause of morbidity in pregnancy. Antenatal clinics use a hemoglobin to screen for ID, which delays the diagnosis of subclinical ID. The aim of this study was to investigate the clinical utility of the percentage of microcytic red cells (%Micro-R), percentage of hypochromic r...

    journal_title:International journal of laboratory hematology

    pub_type: 临床试验,杂志文章

    doi:10.1111/ijlh.12904

    authors: Levy S,Schapkaitz E

    更新日期:2018-12-01 00:00:00

  • Evaluating the analytical performance of five new coagulation assays for the measurement of prothrombin time and activated thromboplastin time.

    abstract:INTRODUCTION:New methods for coagulation tests require careful assessment before routine use. We evaluated the analytical performance of five new coagulation assays for measuring prothrombin time (PT) and activated partial thromboplastin time (aPTT). METHODS:PT Rec, PT Owren, aPTT, aPTT Lupus and aPTT Screen assays (R...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12897

    authors: Kitchen S,Geisen U,Kappelmayer J,Quehenberger P,Drieß J,Lowe A,Jones R,Boehm JG,Miles G,Rozsnyai G

    更新日期:2018-12-01 00:00:00

  • The adsorption of dabigatran is as efficient as addition of idarucizumab to neutralize the drug in routine coagulation assays.

    abstract:INTRODUCTION:The direct thrombin inhibitor dabigatran interferes with thrombophilia screening and with the diagnosis of hemostasis disorders that develop during treatment with the anticoagulant. In vitro addition of idarucizumab, a humanized antibody fragment that binds dabigatran, to plasma samples containing dabigatr...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12807

    authors: Jacquemin M,Toelen J,Feyen L,Schoeters J,Van Horenbeeck I,Vanlinthout I,Debasse M,Vanassche T,Peerlinck K,Verhamme P

    更新日期:2018-08-01 00:00:00

  • Validation of reflex testing rules and establishment of a new workflow for body fluid cell analysis using a Sysmex XN-550 automatic hematology analyzer.

    abstract:INTRODUCTION:We developed and validated reflex testing rules for the microscopic examination (ME) of body fluids (BFs) on the Sysmex XN-550 (Sysmex Corporation) instrument. METHODS:We assessed the detection limits, precision, linearity, and carryover. To develop the reflex testing rules (derivation arm), we tested 515...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12774

    authors: Cho YU,You E,Jang S,Park CJ

    更新日期:2018-06-01 00:00:00

  • Abnormal scattergrams and cell population data generated by fully automated hematological analyzers: New tools for screening malaria infection?

    abstract:INTRODUCTION:Malaria is a life-threatening infectious disease, which has been for long confined to specific endemic areas. Nevertheless, the recent increase in immigration flows from endemic regions and imported cases has reemphasized many diagnostic challenges in Western countries, thus paving the way to introduce rap...

    journal_title:International journal of laboratory hematology

    pub_type: 杂志文章

    doi:10.1111/ijlh.12790

    authors: Buoro S,Manenti B,Seghezzi M,Moioli V,Bagorria M,Callegaro A,Ottomano C,Lippi G

    更新日期:2018-06-01 00:00:00

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