Upregulation of long noncoding RNA Lnc-IRF2-3 and Lnc-ZNF667-AS1 is associated with poor survival in B-chronic lymphocytic leukemia.

abstract：INTRODUCTION:To measure direct factor Xa inhibitor (apixaban, edoxaban, rivaroxaban) concentrations, dedicated chromogenic anti-Xa assays are recommended as suitable methods to provide rapid drug quantification. Moreover, the high-performance liquid chromatography with ultraviolet detection (HPLC-UV) is reported as a r...

journal_title：International journal of laboratory hematology

authors： Cini M,Legnani C,Padrini R,Cosmi B,Dellanoce C,De Rosa G,Marcucci R,Pengo V,Poli D,Testa S,Palareti G

更新日期：2020-04-01 00:00:00

abstract：:Nonvitamin K antagonist oral anticoagulants (NOACs) are being used with increasing frequency due to their safety profile, ease of use, and given that therapeutic monitoring is not required. As these agents have only recently been FDA approved, their effect on routine and specialty coagulation assays is not well apprec...

journal_title：International journal of laboratory hematology

authors： Gosselin RC,Adcock DM

更新日期：2015-05-01 00:00:00

abstract：INTRODUCTION:Physiological changes during pregnancy affect routine tests for iron deficiency. The reticulocyte haemoglobin equivalent (RET-He) and serum-soluble transferrin receptor (sTfR) assay are newer diagnostic parameters for the detection of iron deficiency, combined in the Thomas diagnostic plot. We used this pl...

journal_title：International journal of laboratory hematology

authors： Weyers R,Coetzee MJ,Nel M

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:New generation osmotic gradient ektacytometry has become a powerful procedure for measuring red blood cell deformability and therefore for the diagnosis of red blood cell membrane disorders. In this study, we aim to provide further support to the usefulness of osmotic gradient ektacytometry for the differe...

journal_title：International journal of laboratory hematology

authors： Llaudet-Planas E,Vives-Corrons JL,Rizzuto V,Gómez-Ramírez P,Sevilla Navarro J,Coll Sibina MT,García-Bernal M,Ruiz Llobet A,Badell I,Velasco-Puyó P,Dapena JL,Mañú-Pereira MM

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Autoimmune haemolytic anaemia (AIHA) is defined as the increased destruction of red blood cells (RBCs) in the presence of anti-RBC autoantibodies and/or complement. Its pathogenesis is multifactorial and includes changes in mechanisms of cytokine production and functionality. A number of recent studies hav...

journal_title：International journal of laboratory hematology

authors： D'Abronzo LS,Barros MM,Bordin JO,Figueiredo MS

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Clinical reference intervals represent the normal range of clinical parameters for distinguishing healthy and sick individuals, and they show some variation among different populations. Many reference intervals are still lacking for the pediatric population in China. Thus, the aim of this study was to esta...

journal_title：International journal of laboratory hematology

authors： Sun Q,Yue Y,Tian Y,Wang Q

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Venous blood (VB) sampling for complete blood count (CBC) via venipuncture is the basic method for the daily evaluation of hematological patients. However, several issues during this process, such as venipuncture difficulty and repetitive attempts, may cause pain, phlebitis, hematomas, inadequate sampling,...

journal_title：International journal of laboratory hematology

authors： Oudatzis G,Tsagarakis NJ,Paterakis G,Vasileiou P,Xenou E,Maraki P,Pangrati T,Angelopoulou MK,Vassilakopoulos TP,Konstantopoulos K

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:These recommendations are intended to develop a consensus in the previously published papers as to which parameters and what values should be considered critical. A practical guide on the standardization of critical results management in haematology laboratories would be beneficial as part of good laborato...

journal_title：International journal of laboratory hematology

authors： Keng TB,De La Salle B,Bourner G,Merino A,Han JY,Kawai Y,Peng MT,McCafferty R,International Council for Standardization in Haematology (ICSH).

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Peripheral blood smear (PBS) review is a routine laboratory test which requires pathologist's interpretation when abnormal indices, atypical cells, or critical findings are identified. Real-time remote digital microscopy (DM) can potentially facilitate rapid review when an on-site pathologist is not availa...

journal_title：International journal of laboratory hematology

authors： Haninger DM,Nassiri M,Settembre ED,Zhang S,Zhou J

更新日期：2018-12-01 00:00:00

abstract：:Three major types of rearrangements are involved in acute myeloid leukemias (AML): t(8;21)(q22;q22), inv(16)(p13q22), and 11q23/MLL abnormalities. Their precise identification becomes essential for diagnosis, prognosis, and therapeutic choices. Resulting fusion transcripts (FT) are also powerful markers for monitoring...

journal_title：International journal of laboratory hematology

authors： Giusiano S,Formisano-Tréziny C,Benziane A,Maroc N,Picard C,Hermitte F,Taranger-Charpin C,Gabert J

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:The Sysmex XP-300(®) (XP-300) is a new, fully automated hematology analyzer, designed to generate complete blood counts (CBC) with 3-part differential. In our study, the XP-300 was evaluated as a point-of-care (POC) analyzer in an oncology setting. In which blood samples from patients with different pathol...

journal_title：International journal of laboratory hematology

authors： van Dievoet MA,Louagie H,Ghys T

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Laboratory investigations for bleeding disorders are warranted when an individual has a personal and/or family history of bleeding, and/or laboratory findings that suggest the possibility of an inherited or acquired bleeding disorder. METHODS:This review summarizes author's experience with ordering and re...

journal_title：International journal of laboratory hematology

authors： Hayward CPM

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:In the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway, STAT3 is one of the most prominent prognosis factors for cancer and leukemia. STAT3 activation might promote cellular transformation and therefore have an important role in human tumors. This study aimed to i...

journal_title：International journal of laboratory hematology

authors： Zhong Y,Feng J,Chen B,Cheng L,Li Y,Qian J,Ding J,Gao F,Xia G

更新日期：2012-08-01 00:00:00

abstract：:This 22-year-old women presented to the ante-natal clinic of this hospital for prenatal screening for beta-thalassemia. Cation exchange high performance liquid chromatography (HPLC) using 'Beta Thalassemia Short Program' on Bio-Rad 'Variant' system revealed HbC value of 81.6%. The CBC showed microcytic hypochromic ane...

journal_title：International journal of laboratory hematology

authors： Kumar S,Rana M,Handoo A,Saxena R,Verma IC,Bhargava M,Sood SK

更新日期：2007-10-01 00:00:00

abstract：INTRODUCTION:To retrospectively analyze epidemiological, clinical and hematological characteristics of COVID-19 patients. METHODS:The demographic, symptoms, and physiological parameters of 88 patients were collected and analyzed. The performance of complete blood count (CBC) indexes for monitoring and predicting the s...

journal_title：International journal of laboratory hematology

authors： Zhang H,Cao X,Kong M,Mao X,Huang L,He P,Pan S,Li J,Lu Z

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:The Hematoflow (Beckman Coulter, USA) is a new automated hematology analyzer, which provides a 16-part white blood cell count (WBC) differential. METHODS:We evaluated the differential WBC count performance of the Hematoflow. 101 blood samples from patients were selected for comparison analysis. RESULTS:T...

journal_title：International journal of laboratory hematology

authors： Kim JE,Kim BR,Woo KS,Han JY

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The MRD status detected using multiparameter flow cytometry (MFC) before allogeneic hematopoietic stem cell transplantation (allo-HSCT) has crucial prognostic value for patients with acute myeloid leukemia (AML) in morphologic complete remission (CR). We designed a novel panel of antibodies to identify aberr...

journal_title：International journal of laboratory hematology

authors： Wang Z,Guo M,Zhang Y,Xu S,Cheng H,Wu J,Zhang W,Hu X,Yang J,Wang J,Tang G

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The workflow in clinical flow cytometry laboratories must constantly be reviewed to develop technical procedures that improve quality and productivity and reduce costs. Using the Beckman Coulter dry coating technology, we customized a ten-color tube with dried antibody reagents, designated the Duraclone sc...

journal_title：International journal of laboratory hematology

authors： Correia RP,Rajab A,Bento LC,Alexandre AM,Vaz AC,Schimidell D,Pedro EC,Perin FS,Nozawa ST,Barroso RS,Bacal NS

更新日期：2018-04-01 00:00:00

abstract：:Prediction of the timing of platelet recovery after chemotherapy and hematopoietic stem cell transplantation (HSCT) allows for optimal platelet transfusion. We assessed the clinical utility of the percentage value of the immature platelet fraction (IPF%) monitored using an XE-2100 automated hematology analyzer to pred...

journal_title：International journal of laboratory hematology

authors： Yamaoka G,Kubota Y,Nomura T,Inage T,Arai T,Kitanaka A,Saigo K,Iseki K,Baba N,Taminato T

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Thrombotic complications are a main concern in patients with myeloproliferative neoplasms. Recently, a gain-of-function mutation of the gene encoding the JAK2 tyrosine kinase that results in a valine-to-phenylalanine substitution at position 617 (V617F) has been described. Since the description of the JAK2...

journal_title：International journal of laboratory hematology

authors： Xavier SG,Gadelha T,Rezende SM,Zalcberg IR,Spector N

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Malaria is a life-threatening infectious disease, which has been for long confined to specific endemic areas. Nevertheless, the recent increase in immigration flows from endemic regions and imported cases has reemphasized many diagnostic challenges in Western countries, thus paving the way to introduce rap...

journal_title：International journal of laboratory hematology

authors： Buoro S,Manenti B,Seghezzi M,Moioli V,Bagorria M,Callegaro A,Ottomano C,Lippi G

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:To study the effect of bortezomib alone or in combination with daunorubicin (DNR) on an mdr1 single-factor drug-resistant leukemia cell line K562/MDR1, a multifactor-resistant cell line K562/A02, a drug-sensitive cell line K562, and primary cells from acute myeloid leukemia patients. METHODS:The cell line...

journal_title：International journal of laboratory hematology

authors： Zheng B,Zhou R,Gong Y,Yang X,Shan Q

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:With the progression of blood analysis technology, hematology analyzers become more complex and diverse. How to choose a superb instrument is a challenge for the laboratories. In the essay, we studied whether the newest BC-6000 hematology analyzer meets the needs of a clinical hematology laboratory. METHO...

journal_title：International journal of laboratory hematology

authors： Shen Y,Cao J,Zhou Z,Wang Y,Shen Y,He J

更新日期：2019-10-01 00:00:00

abstract：:Blood coagulation factor XIII (FXIII) plays a key role in the protection of fibrin clot against fibrinolysis, in the cross-linking of fibrin and its mechanical strength. The role of the FXIII-A subunit Val34Leu polymorphism with fatal primary intracerebral hemorrhages (PICH) has not been studied. We evaluated retrospe...

journal_title：International journal of laboratory hematology

authors： Antalfi B,Pongrácz E,Csiki Z,Mezei ZA,Shemirani AH

更新日期：2013-02-01 00:00:00

abstract：:Complex chromosomal aberrations (CCA) can be detected in a substantial proportion of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), which are associated with very poor prognosis. Conventional cytogenetics (CC) cannot accurately define the specific alterations in CCA. Multiplex fluorescence in situ h...

journal_title：International journal of laboratory hematology

authors： Xu W,Li JY,Liu Q,Zhu Y,Pan JL,Qiu HR,Xue YQ

更新日期：2010-02-01 00:00:00

abstract：:The diagnosis of iron deficiency in hospital patients can be difficult in the presence of inflammation. A raised serum transferrin receptor (sTfR) level is useful as a marker of iron deficiency as it is unaffected by inflammation. However, diseases that cause an increase in erythropoietic activity can also result in a...

journal_title：International journal of laboratory hematology

authors： Ong KH,Tan HL,Tam LP,Hawkins RC,Kuperan P

更新日期：2008-12-01 00:00:00

abstract：:Bone marrow aspiration and biopsy can be a painful procedure. Sedation techniques may make this investigation more acceptable to patients, but have the potential to cause life-threatening complications, as well as requiring additional staff and equipment for safe administration. We assessed the use of Entonox, a 50 : ...

journal_title：International journal of laboratory hematology

authors： Gudgin EJ,Besser MW,Craig JI

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Immature platelet fraction (IPF) is a parameter for reticulated platelets. A high percentage IPF (%-IPF) is indicative of consumptive or recovering thrombocytopenic disorders in contrast to a low %-IPF seen in aplastic states. Absolute IPF (A-IPF) specifically reflects the number of immature platelets in c...

journal_title：International journal of laboratory hematology

authors： Ko YJ,Kim H,Hur M,Choi SG,Moon HW,Yun YM,Hong SN

更新日期：2013-10-01 00:00:00

abstract：:Eosinophilia is typically secondary, that is, reactive, in nature and is associated with a wide variety of neoplastic and non-neoplastic disorders. Clonal eosinophilia is also seen in a wide variety of hematopoietic neoplasms, and sub-classification can be diagnostically challenging. A proper evaluation of persistent ...

journal_title：International journal of laboratory hematology

authors： Larsen RL,Savage NM

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Dehydration, fluid shifts or changes in coagulation occurring during air travel can trigger distinct reactions in the haematological system. Athletes are concerned that these effects might impair sporting performance, increase the risk of thrombosis or cause abnormalities in blood values that might be mist...

journal_title：International journal of laboratory hematology

authors： Schumacher YO,Klodt F,Nonis D,Pottgiesser T,Alsayrafi M,Bourdon PC,Voss SC

更新日期：2012-12-01 00:00:00