abstract：:BACKGROUND: Nonadherence and nonpersistence to antidepressants in major depressive disorder (MDD) are common and associated with poor clinical and functional outcomes and increased health care resource utilization (HCRU) and costs. However, contemporary real-world evidence on the economic effect of antidepressant nona...

journal_title：Journal of managed care & specialty pharmacy

authors： Ta JT,Sullivan SD,Tung A,Oliveri D,Gillard P,Devine B

更新日期：2021-02-01 00:00:00

abstract：:BACKGROUND: The economic burden of food allergy is large; however, costs specific to individuals with peanut allergy experiencing reactions to peanuts remain to be evaluated. As the prevalence of peanut allergy continues to increase in children, a better understanding of the cost of care is warranted. OBJECTIVE: To as...

journal_title：Journal of managed care & specialty pharmacy

authors： Blaiss MS,Meadows JA,Yu S,Robison DR,Hass SL,Norrett KE,Guerin A,Latremouille-Viau D,Tilles SA

更新日期：2021-01-20 00:00:00

abstract：:BACKGROUND: Measuring patient perspectives of the quality of health care delivery is an essential component of building a patient-centered model of care, which has garnered increasing emphasis under value-based payment models. Although measurements of patient perspectives of physician practices are common, few validat...

journal_title：Journal of managed care & specialty pharmacy

authors： Carpenter DM,Roberts CA,Farley JF

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Costs associated with biologic switching and discontinuation can be high in chronic inflammatory diseases. Inappropriate use of medications may have cost implications for both payers and patients. Understanding of biologic utilization and switching rates is lacking among patients with ankylosing spondylitis ...

journal_title：Journal of managed care & specialty pharmacy

authors： Yi E,Dai D,Piao OW,Zheng JZ,Park Y

更新日期：2021-01-01 00:00:00

abstract：:DISCLOSURES: No funding supported the writing of this commentary. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Malone DC

更新日期：2020-12-01 00:00:00

abstract：:DISCLOSURES: Funding for the study referred to in this letter was contributed by Bayer Healthcare. Xia and Williamson are employees of Bayer Healthcare. Roth, Carlson, and Sullivan are consultants to Bayer Healthcare. Carlson also reports fees from Adaptive Biotechnologies, unrelated to the study. Roth reports consult...

journal_title：Journal of managed care & specialty pharmacy

authors： Roth JA,Carlson JJ,Xia F,Williamson T,Sullivan SD

更新日期：2020-12-01 00:00:00

abstract：:BACKGROUND: Basal insulin is often recommended as the initial therapy for patients with type 2 diabetes who require insulin treatment. Adequate adherence is critical to diabetes management, yet suboptimal insulin adherence has been reported. Second-generation long-acting (SGLA) insulin has higher dosing flexibility an...

journal_title：Journal of managed care & specialty pharmacy

authors： Zhang H,Barner JC,Moczygemba LR,Rascati KL

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Three pharmacist-specific Current Procedural Terminology (CPT) codes exist to facilitate medication therapy management (MTM) reimbursement (codes 99605, 99606, and 99607). However, no studies have used CPT codes in administrative claims databases to identify subjects who have received MTM services. OBJECTIV...

journal_title：Journal of managed care & specialty pharmacy

authors： Axon DR,Chinthammit C,Tate J,Taylor AM,Leal S,Pickering M,Black H,Warholak T,Campbell PJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The functional impairment associated with migraine can cause physical, emotional, and economic ramifications that can affect occupational, academic, social, and family life. Understanding the relationship between headache-free days (HFDs) and the disease burden of migraine may help with decisions regarding t...

journal_title：Journal of managed care & specialty pharmacy

authors： Lipton RB,Lee L,Saikali NP,Bell J,Cohen JM

更新日期：2020-10-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this commentary. Brummel has consulted, presented, or was engaged in an advisory board for UCB, Boerhinger Ingelheim, Pfizer, and Lilly. Sorenson has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brummel AR,Sorensen TD

更新日期：2020-09-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this letter. Preblick, Ali, and DasMahapatra are employees and shareholders of Sanofi Genzyme. Gray is a postdoctoral fellow at Sanofi Genzyme and Rutgers University. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Preblick R,Gray C,Ali T,DasMahapatra P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The management of sickle cell disease (SCD), an inherited, chronic, and multifaceted condition, is associated with considerable health care resource utilization (HRU) and costs, especially for Medicaid. Anemia affects most patients with SCD and correlates with end-organ damage (EOD), such as stroke, chronic ...

journal_title：Journal of managed care & specialty pharmacy

authors： Campbell A,Cong Z,Agodoa I,Song X,Martinez DJ,Black D,Lew CR,Varker H,Chan C,Lanzkron S

更新日期：2020-09-01 00:00:00

abstract：:The ever-vulnerable medication supply chain is being further strained by the COVID-19 pandemic. Pharmacists in all settings, including managed care, will need to prepare for a potential exacerbation of existing and new drug shortages in the midst of unprecedented crisis. We summarize the major issues, discuss potentia...

journal_title：Journal of managed care & specialty pharmacy

authors： Shuman AG,Fox ER,Unguru Y

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Tisagenlecleucel was approved for the treatment of pediatric and young adult patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (ALL) based on the pivotal ELIANA trial. OBJECTIVE:To comprehensively evaluate the total costs associated with tisagenlecleucel treatment, including costs ...

journal_title：Journal of managed care & specialty pharmacy

authors： Yang H,Hao Y,Qi CZ,Chai X,Wu EQ

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Nonadherence to medication regimens can lead to adverse health care outcomes and increasing costs. OBJECTIVES:To (a) assess the level of medication complexity at an outpatient setting using population-level electronic health record (EHR) data and (b) evaluate its association with medication adherence measur...

journal_title：Journal of managed care & specialty pharmacy

authors： Ma X,Jung C,Chang HY,Richards TM,Kharrazi H

更新日期：2020-07-01 00:00:00

abstract：DISCLOSURES:No funding was required for this project. The authors are or have been members of the Format Executive Committee. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Watkins JB,Sullivan SD,Sampsel E,Fullerton DSP,Graff JS,Fry RN,Lee J,Tam IM,Avey SG

更新日期：2020-06-01 00:00:00

abstract：DISCLOSURES:No funding was received for the writing of this commentary. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Trygstad T

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Diabetes requires close monitoring to achieve optimal outcomes and avoid adverse effects. Continuous glucose monitoring (CGM) is one approach to measuring glycemia and has become more widespread with recent advances in technology; however, ideal implementation of CGM into clinical practice is unknown. CGM ca...

journal_title：Journal of managed care & specialty pharmacy

authors： Sherrill CH,Houpt CT,Dixon EM,Richter SJ

更新日期：2020-05-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this article. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Lever HM

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Research describing patient experience and outcomes with extended half-life recombinant factor VIII (EHL rFVIII) outside of clinical trials is limited. Real-world rFVIII consumption studies, when people with hemophilia A (PWHA) switch from standard half-life (SHL) to EHL rFVIII, may help payers and clinician...

journal_title：Journal of managed care & specialty pharmacy

authors： Aledort L,Milligan S,Watt M,Booth J

更新日期：2020-04-01 00:00:00

abstract：DISCLOSURES:No funding contributed to the writing of this commentary. Brandsema reports consulting for Alexion, Audentes, AveXis, Biogen, Cytokinetics, PTC Therapeutics, Sarepta, and WaVe and has received research funding as a site investigator from Alexion, AveXis, Biogen, CSL Behring, Cytokinetics, Fibrogen, Pfizer, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brandsema JF

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:This study is an evaluation of a discharge intervention that occurred in multiple hospitals across Maryland. In this program, patients received medications at their bedside before discharge with the goal of reducing the risk of primary nonadherence to prescribed medications. OBJECTIVE:To test if the interve...

journal_title：Journal of managed care & specialty pharmacy

authors： Segal JB,Apfel A,Brotman DJ,Shermock KM,Clark JM

更新日期：2020-03-01 00:00:00

abstract：DISCLOSURES:No funding was involved in the writing of this letter. Outside of the submitted work, Hiligsmann has received research grants through institution from Amgen, Radius Health, UCB, and Teva/Theramex. Reginster has received research grants and/or consulting fees from Servier, Novartis, Negma, Lilly, Wyeth, Amge...

journal_title：Journal of managed care & specialty pharmacy

authors： Hiligsmann M,Reginster JY,Silverman S

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Recent evidence has demonstrated that, over 12 months, pharmacy costs associated with switching nonadherent recently relapsed patients from oral atypical antipsychotics (OAAs) to once-monthly paliperidone palmitate (PP1M) were offset by reduced relapse rates and schizophrenia-related health care costs. In ad...

journal_title：Journal of managed care & specialty pharmacy

authors： El Khoury AC,Pilon D,Morrison L,Shak N,Llaneza A,Kim E,Lefebvre P

更新日期：2020-02-01 00:00:00

abstract：:It has been nearly 20 years since the Academy of Managed Care Pharmacy (AMCP) and other stakeholders adopted the Principles for a Sound Formulary System. Since that time, best practices for pharmacy and therapeutics (P&T) committees have matured throughout the health care system. On March 28, 2019, AMCP convened a gro...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2020-01-01 00:00:00

abstract：DISCLOSURES:Funding for this summary was contributed by the Laura and John Arnold Foundation and California Health Care Foundation to the Institute for Clinical and Economic Review (ICER), an independent organization that evaluates the evidence on the value of health care interventions. ICER's annual policy summit is s...

journal_title：Journal of managed care & specialty pharmacy

authors： Pearson SD,Thokala P,Stevenson M,Rind D

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Persistence with multiple daily insulin injections (MDI) may be challenging for patients with type 2 diabetes (T2DM). However, limited information is available regarding the effect of persistence with MDI on outcomes. OBJECTIVE:To evaluate persistence with basal and bolus insulin therapy and assess its rela...

journal_title：Journal of managed care & specialty pharmacy

authors： Edelman SV,Ermakova A,Xiong Y,Sieradzan R,Taylor SD

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Adherence to treatment is correlated with treatment success in chronic myeloid leukemia (CML). CVS Specialty explored novel methods to improve adherence in this population to ensure optimal adherence and lower the risk of unsuccessful treatment. One novel program explored involved an interactive 2-way clinic...

journal_title：Journal of managed care & specialty pharmacy

authors： Sawicki C,Friend KE,Patel R,Polinski JM,Singh S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The management of schizophrenia, a chronic, multifaceted mental health condition, is associated with considerable health care resource utilization (HCRU) and costs. Current evidence indicates that a high-risk and costly prodromal period, during which patients are likely symptomatic, precedes diagnosis. Bette...

journal_title：Journal of managed care & specialty pharmacy

authors： Wallace A,Barron J,York W,Isenberg K,Franchino-Elder J,Sidovar M,Sand M

更新日期：2019-10-01 00:00:00

abstract：DISCLOSURES:No additional funding was received for the writing of this letter. The published study referred to in this letter was funded by Janssen Scientific Affairs, which employs Maiese and funded Cornerstone Research Group, a health economic consulting group, to conduct the study. Grima is a founding partner of Cor...

journal_title：Journal of managed care & specialty pharmacy

authors： Hollmann S,Moldaver D,Goyert N,Grima D,Maiese EM

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Discarding unused drugs after dose changes or discontinuation can significantly affect pharmacy budgets. This is especially concerning for expensive oncology agents. However, few economic studies account for drug wastage, providing an inaccurate estimate of a drug's actual economic cost, cost-effectiveness, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Biskupiak J,Oderda G,Brixner D,Tang D,Zacker C,Dalal AA

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:In the United States, many children with cerebral palsy (CP) obtain health care coverage through managed Medicaid, but little is known about the current demographics or management of this high-need, complex population. OBJECTIVE:To develop U.S. population-level information about the prevalence of CP, manage...

journal_title：Journal of managed care & specialty pharmacy

authors： Pulgar S,Bains S,Gooch J,Chambers H,Noritz GH,Wright E,Sawhney TG,Pyenson B,Ferro C

更新日期：2019-07-01 00:00:00

abstract：DISCLOSURES:No outside funding supported the writing of this letter. Farley has received funding from the National Community Pharmacy Association for previous research. Schondelmeyer advises the University of Minnesota Health Benefit plan on its prescription drug coverage. Urick has received a grant from Cardinal Healt...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Nearly half of statin users discontinue therapy within the first year of treatment. Nonadherence to statin therapy may lead to an increased risk of atherosclerotic cardiovascular disease and, thus, higher costs due to hospitalizations. Value-based care models, such as accountable care organizations (ACO), ar...

journal_title：Journal of managed care & specialty pharmacy

authors： Tamargo C,Sando K,Prados Y,Cowart K

更新日期：2019-05-01 00:00:00

abstract：:Section 3002 of the 21st Century Cures Act, which was signed into law in December 2016, requires the FDA to develop one or more sets of new guidances regarding the collection of patient experience data. To explore how patient-reported outcomes (PROs) can support value-based care and discuss challenges to using PROs mo...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:The misuse of prescription drugs is a serious public health problem. Although controlled substance (CS) prescribing, in particular, opioid analgesics, has recently declined, the volume of prescriptions in 2015 was still 3 times higher than in 1999. To curb the high volume of CS prescribing, a national health...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen X,Ma Q,Barron J,DeVries A,Horn J,Agiro A

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Despite evidence showing the benefits of treatment intensification following an elevated hemoglobin A1c (A1c), clinical inertia, or failure to establish and/or escalate treatment to achieve treatment goals, is a concern among patients diagnosed with type 2 diabetes (T2DM). Clinical inertia may contribute to ...

journal_title：Journal of managed care & specialty pharmacy

authors： Ruiz-Negrón N,Wander C,McAdam-Marx C,Pesa J,Bailey RA,Bellows BK

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The federal 340B Drug Discount Program provides access to significant drug price discounts for health care organizations in the United States that serve a disproportional share of disadvantaged patients. OBJECTIVE:To analyze trends over a 10-year period (2006~2016) in the price of specialty drugs, contrasti...

journal_title：Journal of managed care & specialty pharmacy

authors： Lee CH,Chang J,McCombs J

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The approval of new oral disease-modifying drugs (DMDs), such as fingolimod, dimethyl fumarate (DMF), and teriflunamide, has considerably expanded treatment options for relapsing forms of multiple sclerosis (MS). However, data describing the use of these agents in routine clinical practice are limited. OBJE...

journal_title：Journal of managed care & specialty pharmacy

authors： Desai RJ,Mahesri M,Gagne JJ,Hurley E,Tong A,Chitnis T,Minden S,Spettell CM,Matlin OS,Shrank WH,Choudhry NK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Psoriatic arthritis (PsA) is associated with multiple comorbid conditions, including cardiovascular (CV) comorbidities that impose a considerable burden on patients. Effective management of PsA requires an understanding of comorbidity profiles. OBJECTIVE:To compare the frequency and incidence rates of comor...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaine J,Song X,Kim G,Hur P,Palmer JB

更新日期：2019-01-01 00:00:00