AMCP Partnership Forum: Principles for Sound Pharmacy and Therapeutics (P&T) Committee Practices: What's Next?

abstract：BACKGROUND:Multiple sclerosis (MS) is a neurological degenerative chronic condition without cure. However, long-term disease-modifying therapies (DMTs) help reduce the severity of MS symptoms. Adherence to DMTs is key to their success. Several studies have analyzed what makes patients adherent to their DMTs. As new DMT...

journal_title：Journal of managed care & specialty pharmacy

authors： Higuera L,Carlin CS,Anderson S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Acromegaly is a chronic disorder characterized by excess growth hormone secretion and elevated insulin-like growth factor-1 levels most often caused by a pituitary adenoma. Clinical presentation of the disease includes coarsening of the facial features, soft-tissue swelling of the hands and feet, and overgro...

journal_title：Journal of managed care & specialty pharmacy

authors： Placzek H,Xu Y,Mu Y,Begelman SM,Fisher M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) are a mainstay of treatment for patients suffering from chronic myeloid leukemia (CML). Testing for various mutations in the BCR-ABL gene may help predict lack of response to specific TKIs where resistance has developed. OBJECTIVE:To estimate the emergence of BCR-ABL kinase...

journal_title：Journal of managed care & specialty pharmacy

authors： Ursan ID,Jiang R,Pickard EM,Lee TA,Ng D,Pickard AS

更新日期：2015-02-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this commentary. Brummel has consulted, presented, or was engaged in an advisory board for UCB, Boerhinger Ingelheim, Pfizer, and Lilly. Sorenson has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brummel AR,Sorensen TD

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Lipid screening determines eligibility for statins and other cardiovascular risk reduction interventions. OBJECTIVE:To examine trends in lipid screening among adults aged ≥20 years in a large, multiethnic, integrated health care delivery system in southern California. METHODS:Temporal trends in lipid scree...

journal_title：Journal of managed care & specialty pharmacy

authors： Grant DSL,Scott RD,Harrison TN,Cheetham TC,Chang SC,Hsu JY,Wei R,Boklage SH,Romo-LeTourneau V,Reynolds K

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Clinical pharmacy services were initiated at 7 of 11 clinics within a primary care network (PCN), which was designated as a patient-centered medical home and was affiliated with a large academic medical center in October 2014. The goal of the service was to target patients with uncontrolled chronic condition...

journal_title：Journal of managed care & specialty pharmacy

authors： Prudencio J,Cutler T,Roberts S,Marin S,Wilson M

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Adherence to adjuvant endocrine therapy (AET) for estrogen receptor-positive breast cancer remains suboptimal, which suggests that women are not getting the full benefit of the treatment to reduce breast cancer recurrence and mortality. The majority of studies on adherence to AET focus on identifying factors...

journal_title：Journal of managed care & specialty pharmacy

authors： Farias AJ,Hansen RN,Zeliadt SB,Ornelas IJ,Li CI,Thompson B

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Medication therapy management (MTM) programs were first introduced as a result of the 2003 Medicare Prescription Drug Improvement and Modernization Act. Since then, the Centers for Medicare & Medicaid Services (CMS) have established minimum requirements for health plans to follow in establishing patient elig...

journal_title：Journal of managed care & specialty pharmacy

authors： Miller DE,Roane TE,Salo JA,Hardin HC

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Gout, hyperuricemia, and cardiovascular disease (CVD) are prevalent conditions in the United States, and while they share common risk factors such as obesity, hypertension, hypercholesterolemia, and type 2 diabetes mellitus, relatively little is known about what patient and disease characteristics may link C...

journal_title：Journal of managed care & specialty pharmacy

authors： Pillinger MH,Bangalore S,Klein AB,Baumgartner S,Morlock R

更新日期：2017-06-01 00:00:00

abstract：DISCLOSURES:No funding contributed to the writing of this commentary. Brandsema reports consulting for Alexion, Audentes, AveXis, Biogen, Cytokinetics, PTC Therapeutics, Sarepta, and WaVe and has received research funding as a site investigator from Alexion, AveXis, Biogen, CSL Behring, Cytokinetics, Fibrogen, Pfizer, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brandsema JF

更新日期：2020-04-01 00:00:00

abstract：DISCLOSURES:No outside funding supported the writing of this letter. Farley has received funding from the National Community Pharmacy Association for previous research. Schondelmeyer advises the University of Minnesota Health Benefit plan on its prescription drug coverage. Urick has received a grant from Cardinal Healt...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Despite multiple treatment options, the prognosis of pulmonary arterial hypertension (PAH) remains poor. PAH patients experience a high economic burden due to comorbidities, hospitalizations, and medication costs. Although combination therapy has been shown to reduce hospitalizations, the relationship betwee...

journal_title：Journal of managed care & specialty pharmacy

authors： Burger CD,Ozbay AB,Lazarus HM,Riehle E,Montejano LB,Lenhart G,White RJ

更新日期：2018-08-01 00:00:00

abstract：:DISCLOSURES: No funding supported the writing of this commentary. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Malone DC

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Prescription medication adherence is a known health-related barrier for elderly patients, leading to insufficient disease control and negative health outcomes. The Centers for Medicare & Medicaid Services (CMS) have placed significant emphasis on medication adherence, through the Part D star measures, revolv...

journal_title：Journal of managed care & specialty pharmacy

authors： Winters A,Esse T,Bhansali A,Serna O,Mhatre S,Sansgiry S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Treatment patterns for metastatic colorectal cancer (mCRC) patients have changed considerably over the last decade with the introduction of new chemotherapies and targeted biologics. These treatments are often administered in various sequences with limited evidence regarding their cost-effectiveness. OBJECT...

journal_title：Journal of managed care & specialty pharmacy

authors： Parikh RC,Du XL,Robert MO,Lairson DR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Value-based insurance design (VBID) waives or reduces prescription copayments in order to decrease member cost barriers to refilling medications. Medication therapy management (MTM) is a member clinical intervention designed to reinforce members' knowledge of their medications, which addresses barriers to me...

journal_title：Journal of managed care & specialty pharmacy

authors： Peaslee A,Wickizer M,Olson J,Topp R

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Cancer is a major cause of mortality and a major contributor to health care costs in the United States. An increasing number of cancer patients are treated with oral cancer therapy. Older patients are more likely to have cancer and to be at risk for adherence problems with oral cancer drugs. As a result of s...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaisaeng N,Harpe SE,Carroll NV

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES:To (a) assess how ACOs optimize ...

journal_title：Journal of managed care & specialty pharmacy

authors： Wilks C,Krisle E,Westrich K,Lunner K,Muhlestein D,Dubois R

更新日期：2017-10-01 00:00:00

abstract：UNLABELLED:Medication adherence is a problem that has received widespread attention in the medical literature and health policy circles. With the increased emphasis on recognizing and rewarding quality in the U.S. health care system, medication adherence measures are increasingly being adopted to assess quality of medi...

journal_title：Journal of managed care & specialty pharmacy

authors： Sorensen TD,Pestka DL,Brummel AR,Rehrauer DJ,Ekstrand MJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic, hyper-proliferative dermatological condition associated with joint symptoms known as psoriatic arthritis (PsA). In a 2013 review, the total economic burden of PsA was estimated at $51.7-$63.2 billion. The economic burden of moderate to severe psoriasis patients has reduced significant...

journal_title：Journal of managed care & specialty pharmacy

authors： Lee S,Xie L,Wang Y,Vaidya N,Baser O

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Costs associated with biologic switching and discontinuation can be high in chronic inflammatory diseases. Inappropriate use of medications may have cost implications for both payers and patients. Understanding of biologic utilization and switching rates is lacking among patients with ankylosing spondylitis ...

journal_title：Journal of managed care & specialty pharmacy

authors： Yi E,Dai D,Piao OW,Zheng JZ,Park Y

更新日期：2021-01-01 00:00:00

abstract：:BACKGROUND: The economic burden of food allergy is large; however, costs specific to individuals with peanut allergy experiencing reactions to peanuts remain to be evaluated. As the prevalence of peanut allergy continues to increase in children, a better understanding of the cost of care is warranted. OBJECTIVE: To as...

journal_title：Journal of managed care & specialty pharmacy

authors： Blaiss MS,Meadows JA,Yu S,Robison DR,Hass SL,Norrett KE,Guerin A,Latremouille-Viau D,Tilles SA

更新日期：2021-01-20 00:00:00

abstract：DISCLOSURES:No funding was involved in the writing of this letter. Outside of the submitted work, Hiligsmann has received research grants through institution from Amgen, Radius Health, UCB, and Teva/Theramex. Reginster has received research grants and/or consulting fees from Servier, Novartis, Negma, Lilly, Wyeth, Amge...

journal_title：Journal of managed care & specialty pharmacy

authors： Hiligsmann M,Reginster JY,Silverman S

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies. OBJECTIVE:To evaluate filling of newly prescribed initial bDMARDs for th...

journal_title：Journal of managed care & specialty pharmacy

authors： Harnett J,Wiederkehr D,Gerber R,Gruben D,Bourret J,Koenig A

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Formulary management within a limited budget is critical, especially for specialty drugs, which are used for serious medical conditions and are very expensive. Despite attempts to summarize the pertinent evidence, it is uncertain whether data needs of formulary decision makers for specialty drugs are satisfi...

journal_title：Journal of managed care & specialty pharmacy

authors： Choi Y,Navarro RP

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Adherence to antiretrovirals (ARVs) is critical to achieving durable virologic suppression. OBJECTIVE:To investigate risk factors of poor adherence and the effect of suboptimal adherence on health care resource utilization (HCRU) and costs in Medicaid patients. METHODS:A retrospective longitudinal study wa...

journal_title：Journal of managed care & specialty pharmacy

authors： Dunn K,Lafeuille MH,Jiao X,Romdhani H,Emond B,Woodruff K,Pesa J,Tandon N,Lefebvre P

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The implementation of Medicare Part D provided insurance coverage for outpatient medications, but when persons reach the "gap," they have very limited or no medication insurance coverage until they reach a second threshold for catastrophic coverage. In addition, some patients have a low-income subsidy (LIS),...

journal_title：Journal of managed care & specialty pharmacy

authors： Park H,Rascati KL,Lawson KA,Barner JC,Richards KM,Malone DC

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Poor medication adherence is a predictor of poor health outcomes, especially in populations with chronic diseases. Although several self-reported measures of medication adherence exist, the scope of each is limited.  OBJECTIVE:To identify barriers to medication adherence in order to facilitate effective del...

journal_title：Journal of managed care & specialty pharmacy

authors： Hincapie AL,Taylor AM,Boesen KP,Warholak T

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Recent clinical trials indicate that pharmacogenetic-guided treatment of major depressive disorder (MDD) results in higher treatment response rates by genetically matching patients to medications and avoiding a trial-and-error process. OBJECTIVE:To evaluate the cost-effectiveness of a pharmacogenetic test (...

journal_title：Journal of managed care & specialty pharmacy

authors： Groessl EJ,Tally SR,Hillery N,Maciel A,Garces JA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is associated with substantial morbidity and mortality. With the rise in prevalence of diabetes, there has been an increased need for clinical pharmacy services focused on diabetes management in ambulatory clinics. However, more data IS needed to determine the overall impact that clinical p...

journal_title：Journal of managed care & specialty pharmacy

authors： Chung N,Rascati K,Lopez D,Jokerst J,Garza A

更新日期：2014-09-01 00:00:00