A Physician's Perspective on Generic Drug Quality.

abstract：BACKGROUND:Previous research finds significant variation in spending and utilization across regions, with little evidence of differences in outcomes. While such findings have been interpreted as evidence that spending can be reduced without compromising patient outcomes, the link between spending variation and outcomes...

journal_title：Journal of managed care & specialty pharmacy

authors： Baumgardner J,Shahabi A,Linthicum M,Vine S,Zacker C,Lakdawalla D

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Diabetes is a leading cause of morbidity, mortality, and medical resource utilization in the United States and worldwide. Treatment is aimed at keeping blood glucose levels close to normal and preventing or delaying medical complications. It has been estimated that only 50% of patients with diabetes in the U...

journal_title：Journal of managed care & specialty pharmacy

authors： Saundankar V,Peng X,Fu H,Ascher-Svanum H,Rodriguez A,Ali A,Slabaugh L,Young P,Louder A

更新日期：2016-05-01 00:00:00

abstract：:DISCLOSURES: No funding supported the writing of this commentary. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Malone DC

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Clinical trials have shown that direct oral anticoagulants (DOACs)-including dabigatran, rivaroxaban, apixaban, and edoxaban-are at least as effective and safe as warfarin for the risk of stroke/systemic embolism (SE) and major bleeding (MB) in patients with atrial fibrillation (AF). However, few studies hav...

journal_title：Journal of managed care & specialty pharmacy

authors： Amin A,Keshishian A,Trocio J,Dina O,Le H,Rosenblatt L,Liu X,Mardekian J,Zhang Q,Baser O,Nadkarni A,Vo L

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:New 3-drug regimens have been developed and approved to treat multiple myeloma (MM). The absence of direct comparative data and the high cost of treatment support the need to assess the relative clinical and economic outcomes across all approved regimens. OBJECTIVE:To evaluate the cost-effectiveness of trea...

journal_title：Journal of managed care & specialty pharmacy

authors： Carlson JJ,Guzauskas GF,Chapman RH,Synnott PG,Liu S,Russo ET,Pearson SD,Brouwer ED,Ollendorf DA

更新日期：2018-01-01 00:00:00

abstract：:In a study published last year in the October 2014 issue of the Journal of Managed Care Specialty Pharmacy, Trivedi et al. compared treatment patterns of dasatinib and nilotinib as second-line tyrosine kinase inhibitors (TKI) therapy in chronic myeloid leukemia (CML) patients during the first year of treatment.1 Trive...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen L,Wu EQ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Treatment patterns for metastatic colorectal cancer (mCRC) patients have changed considerably over the last decade with the introduction of new chemotherapies and targeted biologics. These treatments are often administered in various sequences with limited evidence regarding their cost-effectiveness. OBJECT...

journal_title：Journal of managed care & specialty pharmacy

authors： Parikh RC,Du XL,Robert MO,Lairson DR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Recent clinical trials indicate that pharmacogenetic-guided treatment of major depressive disorder (MDD) results in higher treatment response rates by genetically matching patients to medications and avoiding a trial-and-error process. OBJECTIVE:To evaluate the cost-effectiveness of a pharmacogenetic test (...

journal_title：Journal of managed care & specialty pharmacy

authors： Groessl EJ,Tally SR,Hillery N,Maciel A,Garces JA

更新日期：2018-08-01 00:00:00

abstract：:The inclusion of pharmacists on care teams has been shown to improve clinical and economic health outcomes. However, a significant barrier to the widespread incorporation of pharmacists into care teams is the ability to financially support the salary of the pharmacist. A mechanism to improve the ability of pharmacists...

journal_title：Journal of managed care & specialty pharmacy

authors： Dietrich E,Gums JG

更新日期：2018-12-01 00:00:00

abstract：:It has been nearly 20 years since the Academy of Managed Care Pharmacy (AMCP) and other stakeholders adopted the Principles for a Sound Formulary System. Since that time, best practices for pharmacy and therapeutics (P&T) committees have matured throughout the health care system. On March 28, 2019, AMCP convened a gro...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2020-01-01 00:00:00

abstract：DISCLOSURES:No funding was received for the writing of this commentary. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Trygstad T

更新日期：2020-06-01 00:00:00

abstract：:The ever-vulnerable medication supply chain is being further strained by the COVID-19 pandemic. Pharmacists in all settings, including managed care, will need to prepare for a potential exacerbation of existing and new drug shortages in the midst of unprecedented crisis. We summarize the major issues, discuss potentia...

journal_title：Journal of managed care & specialty pharmacy

authors： Shuman AG,Fox ER,Unguru Y

更新日期：2020-08-01 00:00:00

abstract：DISCLOSURES:No outside funding supported the writing of this letter. Farley has received funding from the National Community Pharmacy Association for previous research. Schondelmeyer advises the University of Minnesota Health Benefit plan on its prescription drug coverage. Urick has received a grant from Cardinal Healt...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Current evidence of the effects of pharmacy services on asthma outcomes are not conclusive, since most pharmacy services comprise a variety of interventions. OBJECTIVE:To assess the effect of a service containing self-management support delivered by community pharmacists to patients with asthma. METHODS:A ...

journal_title：Journal of managed care & specialty pharmacy

authors： Dokbua S,Dilokthornsakul P,Chaiyakunapruk N,Saini B,Krass I,Dhippayom T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Encouraging generic drug use has reduced health care costs for payers and consumers, but the availability of therapeutically interchangeable medications or generic medications of choice is not equal across disease states. The extent to which systems of care are able to substitute with generics is not well un...

journal_title：Journal of managed care & specialty pharmacy

authors： Walton SM,Rash C,Lambert BL,Galanter WL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Nonadherence to medication regimens can lead to adverse health care outcomes and increasing costs. OBJECTIVES:To (a) assess the level of medication complexity at an outpatient setting using population-level electronic health record (EHR) data and (b) evaluate its association with medication adherence measur...

journal_title：Journal of managed care & specialty pharmacy

authors： Ma X,Jung C,Chang HY,Richards TM,Kharrazi H

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The Biologics Price Competition and Innovation Act, introduced as part of the Affordable Care Act, directed the FDA to create an approval pathway for biologic products shown to be biosimilar or interchangeable with an FDA-approved innovator drug. These biosimilars will not be chemically identical to the refe...

journal_title：Journal of managed care & specialty pharmacy

authors： AMCP Task Force on Biosimilar Collective Intelligence Systems.,Baldziki M,Brown J,Chan H,Cheetham TC,Conn T,Daniel GW,Hendrickson M,Hilbrich L,Johnson A,Miller SB,Moore T,Motheral B,Priddy SA,Raebel MA,Randhawa G,Surratt

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Psoriatic arthritis (PsA) is associated with multiple comorbid conditions, including cardiovascular (CV) comorbidities that impose a considerable burden on patients. Effective management of PsA requires an understanding of comorbidity profiles. OBJECTIVE:To compare the frequency and incidence rates of comor...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaine J,Song X,Kim G,Hur P,Palmer JB

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Formulary management within a limited budget is critical, especially for specialty drugs, which are used for serious medical conditions and are very expensive. Despite attempts to summarize the pertinent evidence, it is uncertain whether data needs of formulary decision makers for specialty drugs are satisfi...

journal_title：Journal of managed care & specialty pharmacy

authors： Choi Y,Navarro RP

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is associated with substantial morbidity and mortality. With the rise in prevalence of diabetes, there has been an increased need for clinical pharmacy services focused on diabetes management in ambulatory clinics. However, more data IS needed to determine the overall impact that clinical p...

journal_title：Journal of managed care & specialty pharmacy

authors： Chung N,Rascati K,Lopez D,Jokerst J,Garza A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) are a mainstay of treatment for patients suffering from chronic myeloid leukemia (CML). Testing for various mutations in the BCR-ABL gene may help predict lack of response to specific TKIs where resistance has developed. OBJECTIVE:To estimate the emergence of BCR-ABL kinase...

journal_title：Journal of managed care & specialty pharmacy

authors： Ursan ID,Jiang R,Pickard EM,Lee TA,Ng D,Pickard AS

更新日期：2015-02-01 00:00:00

abstract：:Improving medication adherence has been identified as a crucial step towards improving health outcomes for patients with chronic disease and has provided the motivation for many changes in our health care system. Despite the volume of research done on this topic, however, we still lack important basic information abou...

journal_title：Journal of managed care & specialty pharmacy

authors： Seabury SA,Gupta CN,Philipson TJ,Henkhaus LE,PhRMA Medication Adherence Advisory Council.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a multisystem inflammatory disorder characterized by the presence of noncaseating granulomas in involved organs. Prior research has found that sarcoidosis imposes a significant economic burden to U.S. payers. However, the drivers of high health care costs among sarcoidosis patients are unknown...

journal_title：Journal of managed care & specialty pharmacy

authors： Rice JB,White A,Lopez A,Nelson WW

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Poor medication adherence is a predictor of poor health outcomes, especially in populations with chronic diseases. Although several self-reported measures of medication adherence exist, the scope of each is limited.  OBJECTIVE:To identify barriers to medication adherence in order to facilitate effective del...

journal_title：Journal of managed care & specialty pharmacy

authors： Hincapie AL,Taylor AM,Boesen KP,Warholak T

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Concomitant use of stimulants and atypical antipsychotics is common in pediatric attention deficit hyperactivity disorder (ADHD). However, little is known about the determinants of concomitant use and its utility in the management of pediatric ADHD. OBJECTIVES:To (a) examine predictors of concomitant stimul...

journal_title：Journal of managed care & specialty pharmacy

authors： Bali V,Kamble PS,Aparasu RR

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Recent evidence has demonstrated that, over 12 months, pharmacy costs associated with switching nonadherent recently relapsed patients from oral atypical antipsychotics (OAAs) to once-monthly paliperidone palmitate (PP1M) were offset by reduced relapse rates and schizophrenia-related health care costs. In ad...

journal_title：Journal of managed care & specialty pharmacy

authors： El Khoury AC,Pilon D,Morrison L,Shak N,Llaneza A,Kim E,Lefebvre P

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The federal 340B Drug Discount Program provides access to significant drug price discounts for health care organizations in the United States that serve a disproportional share of disadvantaged patients. OBJECTIVE:To analyze trends over a 10-year period (2006~2016) in the price of specialty drugs, contrasti...

journal_title：Journal of managed care & specialty pharmacy

authors： Lee CH,Chang J,McCombs J

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Research describing patient experience and outcomes with extended half-life recombinant factor VIII (EHL rFVIII) outside of clinical trials is limited. Real-world rFVIII consumption studies, when people with hemophilia A (PWHA) switch from standard half-life (SHL) to EHL rFVIII, may help payers and clinician...

journal_title：Journal of managed care & specialty pharmacy

authors： Aledort L,Milligan S,Watt M,Booth J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Formulary or preferred drug list (PDL) management is an effective strategy to ensure clinically efficient prescription drug management by managed care organizations (MCOs). Medicaid MCOs participating in Florida's Medicaid program were required to use a state-mandated PDL between May and August 2014. OBJECT...

journal_title：Journal of managed care & specialty pharmacy

authors： Munshi KD,Mager D,Ward KM,Mischel B,Henderson RR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies. OBJECTIVE:To evaluate filling of newly prescribed initial bDMARDs for th...

journal_title：Journal of managed care & specialty pharmacy

authors： Harnett J,Wiederkehr D,Gerber R,Gruben D,Bourret J,Koenig A

更新日期：2016-03-01 00:00:00