听力与言语-语言病理学

行为科学

医学伦理学

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  • Role of inhibiting Chk1-p53 pathway in hepatotoxicity caused by chronic arsenic exposure from coal-burning.

    abstract::Arsenic is a naturally occurring environmental toxicant, chronic exposure to arsenic can cause multiorgan damage, except for typical skin lesions, liver damage is the main problem for health concern in population with arsenic poisoning. Abnormal apoptosis is closely related to liver-related diseases, and p53 is one of...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120988880

    authors: Yang Y,Liu C,Xie T,Wang D,Chen X,Ma L,Zhang A

    更新日期:2021-01-27 00:00:00

  • Protective effects of Gamma Oryzanol on distant organs after kidney ischemia-reperfusion in rats: A focus on liver protection.

    abstract:BACKGROUND:Acute kidney injury (AKI) is the main clinical concern resulted from ischemia-reperfusion injury (IRI). Ample clinical data indicates that AKI is associated with distant organ dysfunctions and poor patients' outcomes. Oxidative stress and inflammation have a critical role in the pathogenesis of organ injurie...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120979014

    authors: Bagheri Y,Aghajani S,Hosseinzadeh M,Hoshmandan F,Abdollahpour A,Vahed SZ

    更新日期:2020-12-16 00:00:00

  • Effects of psoralen on hepatic bile acid transporters in rats.

    abstract::Fructus Psoraleae (FP), widely used in traditional medicine, is increasingly reported to cause serious hepatotoxicity in recent years. However, the main toxic constituents responsible for hepatotoxicity and the underlying mechanisms are poorly understood. In the present study, psoralen, a main and quality-control cons...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120979346

    authors: Huang J,Wang Q,Chen M,Bi Y,Shi H,Zhou K

    更新日期:2020-12-15 00:00:00

  • Tanshinone ⅡA may alleviate rifampin-induced cholestasis by regulating the expression and function of NTCP.

    abstract::The Na+-taurocholate cotransporting polypeptide (NTCP) acts as the major hepatic basolateral uptake system, and plays a key role in balancing bile flow. The anti-tuberculosis drugs rifampin (RFP) can affect bile flow causing liver injury, while tanshinone IIA (TAN IIA) has the effect of protecting liver. This study ai...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120979030

    authors: Yang Y,Liu L,Xu M,Zhang X,Wang L,He Q,Xu M,Jiang X

    更新日期:2020-12-14 00:00:00

  • Knockdown of TRIM24 suppresses growth and induces apoptosis in acute myeloid leukemia through downregulation of Wnt/GSK-3β/β-catenin signaling.

    abstract::Tripartite motif-containing protein 24 (TRIM24) has currently emerged as a crucial cancer-related gene present in a wide range of human cancer types. However, the involvement of TRIM24 in acute myeloid leukemia (AML) has not been well investigated. The present study aims to investigate the significance, cellular funct...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120938845

    authors: Li C,Xin H,Shi Y,Mu J

    更新日期:2020-12-01 00:00:00

  • MiR-663a, regulated by lncRNA GAS5, contributes to osteosarcoma development through targeting MYL9.

    abstract::Osteosarcoma is characterized by high malignancy and high metastasis rate, resulting in high mortality and disability. MiR-663a has been reported in a variety of tumors to promote tumorigenesis. However, miR-663a has not been reported in the pathogenesis of osteosarcoma. Bioinformatics analysis and experiments includi...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120937330

    authors: Zhao S,Xiong W,Xu K

    更新日期:2020-12-01 00:00:00

  • Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users.

    abstract:BACKGROUND:The widespread use of synthetic cannabinoids (SCs) among youth has become an important public health problem. Several life-threatening side effects of SC have been reported, including cardiovascular, gastrointestinal, neurological, renal, metabolic, ophthalmologic, and pulmonary effects, besides skin toxicit...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120930057

    authors: Guler EM,Bektay MY,Akyildiz AG,Sisman BH,Izzettin FV,Kocyigit A

    更新日期:2020-11-01 00:00:00

  • 3,4-Methylenedioxymethamphetamine causes retinal damage in C57BL/6J mice.

    abstract::3,4-Methylenedioxymethamphetamine (MDMA) is a powerfully addictive psychostimulant with pronounced effects on the central nervous system, but the precise mechanism of MDMA-induced toxicity remains unclear, specifically on the retina. This study was performed to investigate the effects of MDMA treatment on the retina a...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120930253

    authors: Ma Y,Bian C,Song D,Yao G,Nie R

    更新日期:2020-11-01 00:00:00

  • Cinnamomum cassia ameliorates Ni-NPs-induced liver and kidney damage in male Sprague Dawley rats.

    abstract::Nickel nanoparticles (Ni-NPs) have been widely used in various industries related to electronics, ceramics, textiles, and nanomedicine. Ambient and occupational exposure to Ni-NPs may bring about potential detrimental effects on animals and humans. Thus, there is a growing effort to identify compounds that can amelior...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120930125

    authors: Iqbal S,Jabeen F,Peng C,Ijaz MU,Chaudhry AS

    更新日期:2020-11-01 00:00:00

  • Induction of apoptosis in indole-3-carbinol-treated lung cancer H1299 cells via ROS level elevation.

    abstract::This study was focused on investigating the anticancer potential of indole-3-carbinol (I3C) against lung cancer H1299 cells via an increase in ROS levels. To investigate the induction of growth arrest and/or cell death in H1299 cells, a cell cycle arrest assay, terminal deoxynucleotidyl transferase (TdT)-mediated dUTP...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120969968

    authors: Lim HM,Park SH,Nam MJ

    更新日期:2020-10-29 00:00:00

  • Effects of TNF-α antagonist infliximab on fructose-induced metabolic syndrome in rats.

    abstract::Public health issues have been raised regarding fructose toxicity and its serious metabolic disorders. Deleterious effects of high fructose intake on insulin sensitivity, body weight, lipid homeostasis have been identified. The new millennium has witnessed the emergence of a modern epidemic, the metabolic syndrome (MS...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120969960

    authors: Abdelhamid YA,Elyamany MF,Al-Shorbagy MY,Badary OA

    更新日期:2020-10-29 00:00:00

  • Association between blood aluminum and beta-2 receptor gene methylation with childhood asthma control.

    abstract::Previous studies have shown that environmental exposure to heavy metals has been related to epigenetic changes, such as DNA methylation in receptors involved in pathogenesis of asthma. One of these receptors is beta-2 adrenergic receptor (ADRB2). We conducted this study to examine the association between blood aluminu...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120921436

    authors: Nafea OE,El-Korashi LA,Gehad MH,Yousif YM,Zake LG

    更新日期:2020-10-01 00:00:00

  • P38-β/SAPK-inhibiting and apoptosis-inducing activities of (E)-4-chloro-2-((3-ethoxy-2-hydroxybenzylidene) amino)phenol.

    abstract::The present study has three purposes; first evaluating cytotoxicity of (E)-4-chloro-2-((3-ethoxy-2-hydroxybenzylidene)amino)phenol (ACES), second deciphering ACES-mediated cellular death mechanism, and third estimating ACES-mediated alterations in the expressions of mitogen-activated protein kinase (MAPK) pathway-rela...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120924112

    authors: Karaosmanoğlu O

    更新日期:2020-10-01 00:00:00

  • Action of the insecticide cyfluthrin on Ca2+ signal transduction and cytotoxicity in human osteosarcoma cells.

    abstract::Cyfluthrin is a pyrethroid insecticide and common household pesticide. The effect of cyfluthrin on Ca2+-related physiology in human osteosarcoma is unclear. This study investigated the effect of cyfluthrin on cytosolic-free Ca2+ concentrations ([Ca2+]i) and viability in MG63 human osteosarcoma cells. Cyfluthrin concen...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120918298

    authors: Lu YC,Liang WZ,Kuo CC,Hao LJ,Chou CT,Jan CR

    更新日期:2020-09-01 00:00:00

  • Histoprotective effect of rutin against cisplatin-induced toxicities in tumor-bearing mice: Rutin lessens cisplatin-induced toxicities.

    abstract::Cisplatin is an effective anticancer drug used against a variety of cancers. The full therapeutic potential of cisplatin is often hampered due to concurrent development of various side effects in the hosts. Rutin, a naturally occurring bioflavonoid shows several pharmacological activities. It has been earlier reported...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120947793

    authors: Prasad R,Prasad SB

    更新日期:2020-08-13 00:00:00

  • Sulfur dioxide induces vascular relaxation through PI3K/Akt/eNOS and NO/cGMP signaling pathways in rats.

    abstract::Sulfur dioxide (SO2) is a common exogenous atmospheric pollutant. Studies have shown that SO2 can cause vasodilation as a gas signaling molecule, but the specific signaling pathways are not well understood. This study aimed to explore the underlying mechanism behind the effects of SO2 on vasodilation of isolated rat a...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120911428

    authors: Zhang Q,Lyu W,Yu M,Niu Y

    更新日期:2020-08-01 00:00:00

  • Cyclophosphamide induces a significant increase in iron content in the liver and spleen of mice.

    abstract:OBJECTIVE:Oxidative stress is one of the major mechanisms of cyclophosphamide (CPX)-induced toxicities. However, it is unknown how CPX induces oxidative stress. Based on the available information, we speculated that CPX could increase iron content in the tissues and then induce oxidative stress. METHOD:We tested this ...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120909880

    authors: Sheng Y,Chen YJ,Qian ZM,Zheng J,Liu Y

    更新日期:2020-07-01 00:00:00

  • Features reported after exposure to automatic dishwashing rinse aids.

    abstract:INTRODUCTION:Automatic dishwashing rinse aids are drying aids which contain non-ionic surfactants, usually ethoxylated alcohols, typically at concentrations of ≤30%. OBJECTIVE:To assess the reported toxicity of rinse aids. METHODS:Telephone enquiries to the UK National Poisons Information Service were analysed from J...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120901580

    authors: Day R,Bradberry SM,Sandilands EA,Thomas S,Thompson JP,Vale JA

    更新日期:2020-06-01 00:00:00

  • Cytochrome P450 4B1 (CYP4B1) as a target in cancer treatment.

    abstract::Cytochrome P450 4B1 (CYP4B1) plays crucial roles in biotransforming of xenobiotics. Its predominant extrahepatic expression has been associated with certain tissue-specific toxicities. However, the expressions of CYP4B1 in various cancers and hence their potential roles in cancer development were inclusive. In this wo...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120905959

    authors: Lim S,Alshagga M,Ong CE,Chieng JY,Pan Y

    更新日期:2020-06-01 00:00:00

  • Current and research therapies for the prevention and treatment of delayed neurological syndrome associated with carbon monoxide poisoning: A narrative review.

    abstract::Severe carbon monoxide (CO) poisoning causes fulminant deaths in common environment as well as neurological sequelae to survivors. Prevention of delayed neurological syndrome (DNS) after exposure to CO, the most important sequela, is based up to date on hyperbaric oxygen administration. Nevertheless, its use remains c...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327120901572

    authors: Del Moral-Barbudo B,Blancas R,Ballesteros-Ortega D,Quintana-Díaz M,Martínez-González Ó

    更新日期:2020-06-01 00:00:00

  • Effect of heat-killed Enterococcus faecalis EF-2001 on ethanol-induced acute gastric injury in mice: Protective effect of EF-2001 on acute gastric ulcer.

    abstract::Enterococcus faecalis is a facultative anaerobic gram-positive commensal bacterium common in the gastrointestinal tract of animals and humans. This study aimed to investigate the protective effects of heat-killed E. faecalis EF-2001 (EF-2001) on acute gastric ulcer using a murine model of ethanol (EtOH)-induced acute ...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119899987

    authors: Jeon DB,Shin HG,Lee BW,Jeong SH,Kim JH,Ha JH,Park JY,Kwon HJ,Kim WJ,Ryu YB,Lee IC

    更新日期:2020-05-01 00:00:00

  • Inhibition of miR-182-5p attenuates pulmonary fibrosis via TGF-β/Smad pathway.

    abstract::Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with high morbidity and mortality. miR-182-5p is overexpressed in several fibrosis-related diseases but its effect in pulmonary fibrosis has not been reported yet. To investigate the function of miR-182-5p in pulmonary fibrosis, we establish...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119895549

    authors: Chen Y,Zhang Q,Zhou Y,Yang Z,Tan M

    更新日期:2020-05-01 00:00:00

  • Pyrvinium pamoate inhibits proliferation and invasion of human endometriotic stromal cells.

    abstract::Endometriosis is characterized by the presence of functional endometrial tissue in other pelvic organs. This gynecologic problem occurs in 35-50% of women with pain and infertility. Endometriotic cells share some characteristics such as proliferation, migration, and invasion with tumor cells. Pyrvinium pamoate, an ant...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119896612

    authors: Karamian A,Nazarian H,Ziai SA,Zarnani AH,Salehpour S,Paktinat S,Novin MG

    更新日期:2020-05-01 00:00:00

  • Combined therapy of gabapentin with pantoprazole exhibited better protective action against forestomach and pylorus ligation-induced gastric esophageal reflux disease in albino Wistar rats.

    abstract::The current study was undertaken to evaluate the effect of combined therapy of gabapentin and pantoprazole against forestomach and pylorus ligation-induced gastric esophageal reflux disease (GERD) in albino Wistar rats. Rats were randomly divided into five groups, each group consisting of six rats, fasted for 24 h, un...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119893409

    authors: Arya P,Kaithwas G

    更新日期:2020-04-01 00:00:00

  • Environmental polycyclic aromatic hydrocarbons mixture, in human blood levels, decreased oestradiol secretion by granulosa cells via ESR1 and GPER1 but not ESR2 receptor.

    abstract::Tissue-dependent oestrogenic and anti-oestrogenic activity of polycyclic aromatic hydrocarbons (PAHs) has been suggested. In this study, the effect of two PAH mixtures, M1 composed of all 16 priority pollutants and M2 composed of five (noted in the highest levels) compounds, on follicle-stimulating hormone receptor (F...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119886027

    authors: Zajda K,Gregoraszczuk EL

    更新日期:2020-03-01 00:00:00

  • Systemic administration with tetrahydrocannabinol causes retinal damage in BALB/c mice.

    abstract::Recent years have seen substantial shifts in cultural attitudes towards cannabis for medical and recreational use. However, legalizing recreational marijuana may have adverse effects on individual and public health. As the most widely used illicit agent, cannabis is commonly reported to disrupt learning and memory. Un...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119886037

    authors: Zhang Z,Li R,Lu H,Zhang X

    更新日期:2020-03-01 00:00:00

  • Evaluation of complete blood count parameters, cell ratios, and cell volume indices in mushroom poisonings.

    abstract:OBJECTIVE:Mushroom poisoning is still a significant health-care problem, with the potential to affect blood parameters. The present study analyses the effect of mushroom poisoning on complete blood cell parameters, cell ratios, and cell volume indices and the effect of the mentioned parameters on prognosis/hospital len...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119855131

    authors: Doğan M,Karahan I

    更新日期:2019-10-01 00:00:00

  • Serum ammonia as an early predictor of in-hospital mortality in patients with glufosinate poisoning.

    abstract:BACKGROUND:The mortality rate associated with human glufosinate poisoning is high. We evaluated the usefulness of serum ammonia and sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation II (APACHE II) scores for early prediction of in-hospital mortality in glufosinate ammonium po...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119855124

    authors: Lee J,Lee Y,Kim YS,Choi JG,Go TH,Kim H,Cha YS

    更新日期:2019-09-01 00:00:00

  • Heat-killed probiotic bacteria induce apoptosis of HT-29 human colon adenocarcinoma cell line via the regulation of Bax/Bcl2 and caspases pathway.

    abstract::Apoptosis induction in cancer cells is one of the most efficient ways to treat cancer and find anticancer compounds. The aim of this study was to evaluate the cytotoxic effects of heat-killed indigenous probiotic bacteria and apoptosis induction in the HT-29 human colon adenocarcinoma cell line. The growth-inhibitory ...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119851255

    authors: Karimi Ardestani S,Tafvizi F,Tajabadi Ebrahimi M

    更新日期:2019-09-01 00:00:00

  • Evaluation and comparison of cytotoxicity, genotoxicity, and apoptotic effects of poly-l-lysine/plasmid DNA micro- and nanoparticles.

    abstract::The principal impediment to gene therapy is the development of efficient, nontoxic gene carriers that can handle and deliver foreign genetic materials into various cell types, including healthy and cancerous cells. Poly-l-lysine (PLL) polymers are one of the most favorable gene carriers among nonviral vectors, and PLL...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119846924

    authors: Alinejad-Mofrad E,Malaekeh-Nikouei B,Gholami L,Mousavi SH,Sadeghnia HR,Mohajeri M,Darroudi M,Oskuee RK

    更新日期:2019-08-01 00:00:00

  • DNA damage and methylation induced by organophosphate flame retardants: Tris(2-chloroethyl) phosphate and tris(1-chloro-2-propyl) phosphate in human peripheral blood mononuclear cells.

    abstract::Phosphorus flame retardants are a group of chemicals that are used to slow or prevent the spread of fire. These compounds have been detected in different environments including human organism. In the present study, we have investigated DNA-damaging potential and effect on DNA methylation of tris(2-chloroethyl) phospha...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119839174

    authors: Bukowski K,Wysokinski D,Mokra K,Wozniak K

    更新日期:2019-06-01 00:00:00

  • MicroRNA from a 12-h versus 20-h acetylcysteine infusion for paracetamol overdose.

    abstract::Paracetamol overdose is common and microRNA (miR)-122 expression is increased with liver injury. We aimed to measure miR-122 in the setting of an abbreviated paracetamol overdose treatment regimen. We compared miRNA expression in patients treated for paracetamol poisoning with an abbreviated 12-h intravenous acetylcys...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119833740

    authors: Wong A,Nejad C,Gantier M,Choy KW,Doery J,Graudins A

    更新日期:2019-06-01 00:00:00

  • Vulpinic acid, a lichen metabolite, emerges as a potential drug candidate in the therapy of oxidative stress-related diseases, such as atherosclerosis.

    abstract::Vulpinic acid, a lichen compound, has been shown to have many beneficial effects and its medicinal value increases day by day. As in atherosclerosis, endothelial damage is the basis of many diseases. The aim of this study is to investigate the effects of vulpinic acid against oxidative stress damage induced by hydroge...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119833745

    authors: Sahin E,Dabagoglu Psav S,Avan I,Candan M,Sahinturk V,Koparal AT

    更新日期:2019-06-01 00:00:00

  • N-nitrosodimethylamine (NDMA) induced apoptosis dependent on Fas/FasL complex in human leukocytes.

    abstract:OBJECTIVE:To investigate the mechanism of apoptosis dependent on the Fas/FasL (Fas ligand) complex in the presence of N-nitrosodimethylamine (NDMA) in human leukocytes. METHODS:Polymorphonuclear neutrophils (PMNs) and peripheral blood mononuclear cells (PBMCs) were isolated form whole blood by density centrifugation. ...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119828198

    authors: Iwaniuk A,Grubczak K,Ratajczak-Wrona W,Garley M,Nowak K,Jabłońska E

    更新日期:2019-05-01 00:00:00

  • Stereological examination of effects of ethanol on optic nerve in experimental alcohol model.

    abstract::The objective of the present study was to perform histological and stereological examination of alcohol-induced changes in the optic nerve, considered an extension of white matter of the brain, in rats. This study included 20 male Wistar albino rats aged 60 days and weighing 190-220 g. The rats were divided into three...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327119828123

    authors: Igit T,Colcimen N

    更新日期:2019-05-01 00:00:00

  • Evaluation of biochemical changes in dental tissues after different office bleaching methods.

    abstract::The color of the teeth is an important topic for many people and can be influenced by intrinsic and extrinsic stains. There is an increasing demand for whitening of the teeth year by year. The most popular way of whitening is "bleaching," which is the result of the breakdown of pigments located in the enamel and/or th...

    journal_title:Human & experimental toxicology

    pub_type: 临床试验,杂志文章

    doi:10.1177/0960327118817103

    authors: Karaarslan ES,Özmen ZC,Aytac F,Bicakci AA,Buldur M,Aydogan L,Hologlu F,Özkocak B

    更新日期:2019-04-01 00:00:00

  • Sex-specific differences in the regulation of inducible nitric oxide synthase by bisphenol A in neutrophils.

    abstract::The aim of the study was to evaluate the effect of bisphenol A (BPA) on nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression by neutrophils with regard to sex and nuclear factor-κB (NF-κB) pathway participation in this process. This study demonstrated that BPA intensifies the production o...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327118793188

    authors: Ratajczak-Wrona W,Nowak K,Garley M,Tynecka M,Jablonska E

    更新日期:2019-02-01 00:00:00

  • Periostin alters transcriptional profile in a rat model of isoproterenol-induced cardiotoxicity.

    abstract::Periostin is an extracellular matrix protein from the fasciclin family that guides cellular trafficking and extracellular matrix organization. Periostin stimulates mature cardiomyocytes to reenter the cell cycle. The molecular mechanism behind such stimulation remains to be explored. A DNA microarray technology consti...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327118802617

    authors: Sözmen M,Devrim AK,Kabak YB,Devrim T

    更新日期:2019-02-01 00:00:00

  • Comparative cytotoxicity and apoptotic pathways induced by nanosilver in human liver HepG2 and L02 cells.

    abstract::Silver nanoparticles are used in many commercial products in daily life. Exposure to nanosilver has hepatotoxic effects in animals. This study investigated the cytotoxicity associated with polyvinylpyrrolidone-coated nanosilver (23.44 ± 4.92 nm in diameter) exposure in the human hepatoma cell line (HepG2) and normal h...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327118769718

    authors: Xue Y,Wang J,Huang Y,Gao X,Kong L,Zhang T,Tang M

    更新日期:2018-12-01 00:00:00

  • Role of metformin on base excision repair pathway in p53 wild-type H2009 and HepG2 cancer cells.

    abstract::The antidiabetic agent metformin was shown to further possess chemopreventive and chemotherapeutic effects against cancer. Despite the advances, the underlying molecular mechanisms involved in decreasing tumor formation are still unclear. The understanding of the participation of oxidative stress in the action mechani...

    journal_title:Human & experimental toxicology

    pub_type: 杂志文章

    doi:10.1177/0960327117737145

    authors: Dogan Turacli I,Candar T,Yuksel BE,Demirtas S

    更新日期:2018-09-01 00:00:00

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