abstract：BACKGROUND:Myocarditis is an inflammatory disease of the myocardium, which leads to cardiac dysfunction and heart failure. Previous studies have suggested that complex cross-talk between innate and adaptive immune responses is involved in the pathogenesis of acute myocarditis. Immunohistochemistry is the current standa...

journal_title：Journal of cardiology

authors： Kawada JI,Takeuchi S,Imai H,Okumura T,Horiba K,Suzuki T,Torii Y,Yasuda K,Imanaka-Yoshida K,Ito Y

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Current guidelines recommend early termination of triple therapy and the use of direct oral anticoagulants (DOAC) for non-valvular atrial fibrillation (NVAF) patients who undergo percutaneous coronary intervention (PCI), due to safety concerns. However, to date, real-world medication usage and safety outcome...

journal_title：Journal of cardiology

authors： Nakamura M,Yamashita T,Hayakawa A,Matsumoto T,Takita A,Hasegawa C,Uchino K,Sekine T,Iizuka T,Tanabe H,Kogure S

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Early graft failure can affect the short- and long-term outcomes of patients undergoing coronary bypass grafting surgery (CABG). The aim of our study was to explore the predictive value of transit-time flow measurement (TTFM) parameters for early graft failure (before discharge) after CABG in different coron...

journal_title：Journal of cardiology

authors： Zhang G,Zhao Z,Han Z,Gao Q,Liu J,Chen Y

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The impairment of short-term heart rate regulation in patients with heart failure with preserved ejection fraction (HFpEF) can cause acute hemodynamic collapse. Detrended fluctuation analysis (DFA) is a useful tool for the diagnosis of heart diseases and the prediction of mortality. In DFA, the short-term sc...

journal_title：Journal of cardiology

authors： Mizobuchi A,Osawa K,Tanaka M,Yumoto A,Saito H,Fuke S

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Heart failure (HF) is a risk factor for adverse post-procedural outcome after revascularization; however, it is unclear how left ventricular systolic dysfunction (LVSD) and clinical HF symptoms affect percutaneous coronary intervention (PCI) outcomes. We investigated the characteristics and long-term outcome...

journal_title：Journal of cardiology

authors： Kimura M,Kohno T,Sawano M,Heidenreich PA,Ueda I,Takahashi T,Matsubara T,Ueno K,Hayashida K,Yuasa S,Ohki T,Fukuda K,Kohsaka S

更新日期：2021-01-01 00:00:00

abstract：:Diabetic cardiomyopathy, clinically diagnosed as ventricular dysfunction in the absence of coronary atherosclerosis or hypertension in diabetic patients, is a cardiac muscle-specific disease that increases the risk of heart failure and mortality. Its clinical course is characterized initially by diastolic dysfunction,...

journal_title：Journal of cardiology

authors： Kanamori H,Naruse G,Yoshida A,Minatoguchi S,Watanabe T,Kawaguchi T,Tanaka T,Yamada Y,Takasugi H,Mikami A,Minatoguchi S,Miyazaki T,Okura H

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Sarcopenia is one of the important predictors of heart failure (HF) in patients with cardiac problems. Skeletal muscle pump is important to maintain Fontan circulation. We aimed to quantify the volume of the psoas major muscle (PMM) and investigate whether it is relevant to HF hospitalization in adults with ...

journal_title：Journal of cardiology

authors： Shiina Y,Nagao M,Shimomiya Y,Inai K

更新日期：2021-01-01 00:00:00

abstract：:Functional mitral regurgitation (MR) has been traditionally known as secondary MR resulting from left ventricular (LV) dilatation and systolic dysfunction. However, deterioration of functional MR also relates to mitral annular (MA) dilatation. Furthermore, MA dilatation due to left atrial dilatation in patients with a...

journal_title：Journal of cardiology

authors： Abe Y,Takahashi Y,Shibata T

更新日期：2020-12-18 00:00:00

abstract：BACKGROUND:Although the Klotho gene is recognized as an aging-suppressor gene, the clinical significance of its soluble product, soluble Klotho, in coronary artery disease (CAD) has not been completely determined. The relationship between soluble Klotho and coronary artery calcification (CAC) was investigated in patien...

journal_title：Journal of cardiology

authors： Koga S,Ikeda S,Akashi R,Yonekura T,Kawano H,Maemura K

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:A better understanding of the epidemiology of pediatric out-of-hospital cardiac arrest (OHCA) occurring in nursery schools and kindergartens is indispensable to establish an evidence-based strategy for prevention and improved outcomes. This study aimed to describe the incidence, characteristics, and outcomes...

journal_title：Journal of cardiology

authors： Kiyohara K,Kitamura T,Ayusawa M,Nitta M,Iwami T,Nakata K,Matsui S,Sobue T,Kitamura Y,SPIRITS investigators.

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Patients with coronary artery disease (CAD) are at high risk of atherosclerotic events. The aim of this meta-analysis is to evaluate the cardiovascular protective effect of colchicine on patients with CAD. METHODS:In this systematic review and meta-analysis, we searched PubMed and Embase for studies publish...

journal_title：Journal of cardiology

authors： Tien YY,Huang HK,Shih MC,Tu YK

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Early recognition of cardiac arrest is essential for increasing the likelihood of successful resuscitation. However, many factors could obstruct the recognition of cardiac arrest and delay the delivery of cardiopulmonary resuscitation and automated external defibrillator use. We have developed a new system u...

journal_title：Journal of cardiology

authors： Hatakeyama T,Kobayashi D,Otani T,Nishimura T,Hidari H,Miyoshi H,Sakaida K,Kawamura T,Iwami T

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Third-generation drug-eluting-stents (3rd DES) may improve coronary arterial healing and reduce neoatherosclerosis formation. We evaluated post-stent findings and subsequent vascular healing of 3rd DES by comparing to second-generation drug-eluting-stents (2nd DES) at intermediate-term follow-up using optica...

journal_title：Journal of cardiology

authors： Miura T,Sonoda S,Sanuki Y,Naka Y,Okabe H,Setoyama K,Inoue K,Shimizu A,Anai R,Tsuda Y,Araki M,Otsuji Y

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:There are two types of circulating proprotein convertase subtilisin/kexin type 9 (PCSK9), mature and furin-cleaved. Most types of lipoprotein(a) [Lp(a)], an independent risk factor of cardiovascular events, bind to mature PCSK9. OBJECTIVE:This study examined the effects of monoclonal anti-PCSK9 antibody on ...

journal_title：Journal of cardiology

authors： Nakamura A,Kanazawa M,Kagaya Y,Kondo M,Sato K,Endo H,Nozaki E

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Regional differences in the profile and treatment strategies of patients with cardiometabolic diseases have been studied in several different countries. The Cardio-Vascular and metabolic treatments in Canada: Assessment of REal-life therapeutic value (CV-CARE) registry was designed to evaluate patient profil...

journal_title：Journal of cardiology

authors： Goldenberg R,Bell A,Cheng W,Paron E,Fils-Aimé N,Burrows M,Blavignac J,Barakat M

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:There has been no study elucidating whether cognitive impairment (CI) can provide additive prognostic information besides that provided by preexisting prognostic factors in elderly patients with heart failure. This study examined whether CI can provide additive prognostic information in elderly patients with...

journal_title：Journal of cardiology

authors： Saito H,Yamashita M,Endo Y,Mizukami A,Yoshioka K,Hashimoto T,Koseki S,Shimode Y,Kitai T,Maekawa E,Kasai T,Kamiya K,Matsue Y

更新日期：2020-10-01 00:00:00

abstract：:Although the mechanism for the occurrence of acute myocardial infarction (MI) has been investigated by many pathological and clinical studies, it has not been adequately clarified yet. Although the disruption of vulnerable plaque is a well-known cause of acute MI, there are many silent plaque disruptions detected in t...

journal_title：Journal of cardiology

authors： Ueda Y,Kosugi S,Abe H,Ozaki T,Mishima T,Date M,Uematsu M,Koretsune Y

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Patients experiencing out-of-hospital cardiac arrest (OHCA) and subsequent post-cardiac arrest syndrome are often compromised by multi-organ failure. The Sequential Organ Failure Assessment (SOFA) score has been used to predict clinical outcome of patients requiring intensive care for multi-organ failure. Th...

journal_title：Journal of cardiology

authors： Matsuda J,Kato S,Yano H,Nitta G,Kono T,Ikenouchi T,Murata K,Kanoh M,Inamura Y,Takamiya T,Negi K,Sato A,Yamato T,Inaba O,Morita H,Matsumura Y,Nitta J,Yonetsu T

更新日期：2020-09-01 00:00:00

abstract：:A number of devices can now provide mechanical circulatory support (MCS) to patients with acute cardiogenic shock (CS) and chronic end-stage heart failure (HF). Women differ from men in pathophysiology and natural history of CS and HF, and are usually sicker at admission. Current evidence suggests that women benefit a...

journal_title：Journal of cardiology

authors： Dayanand S,Martinez JM,Figueredo VM,Gupta S

更新日期：2020-08-29 00:00:00

abstract：:Despite recent developments in various therapies, heart failure remains a leading cause of morbidity and mortality worldwide. New pharmacological approaches are therefore needed to improve the outcomes of patients with heart failure. Diabetes mellitus is an important risk factor for heart failure, but until recently t...

journal_title：Journal of cardiology

authors： Nakagawa Y,Kuwahara K

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Serum levels of lipoprotein (a) [Lp(a)] have been reported as a residual risk marker for adverse events in patients with coronary artery disease (CAD). However, the prognostic impact of Lp(a) on long-term clinical outcomes among diabetic patients on statin therapy after percutaneous coronary intervention (PC...

journal_title：Journal of cardiology

authors： Takahashi N,Dohi T,Funamizu T,Endo H,Wada H,Doi S,Kato Y,Ogita M,Okai I,Iwata H,Okazaki S,Isoda K,Miyauchi K,Shimada K

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that the incidence of atrial fibrillation (AF) was significantly increased when patients aged ≥40 years had surgical atrial septal defect (ASD) closure (sASD). However, limited information is available on such findings in transcatheter ASD closure (tASD). The purpose of this stu...

journal_title：Journal of cardiology

authors： Fujii Y,Akagi T,Nakagawa K,Takaya Y,Eto K,Kuroko Y,Kotani Y,Ejiri K,Ito H,Kasahara S

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Although the level of uric acid (UA) is higher in males, increased UA level in females was reported to be closely associated with prevalence of metabolic syndrome (Mets) leading to atherosclerotic cardiovascular disease (ASCVD). Few data exist regarding the gender diferences in relationship between the serum...

journal_title：Journal of cardiology

authors： Tani S,Matsuo R,Imatake K,Suzuki Y,Takahashi A,Yagi T,Matsumoto N,Okumura Y

更新日期：2020-07-01 00:00:00

abstract：:Numerous epidemiological and animal studies disclosed that birth weight is inversely associated with the incidence of the lifestyle-related disorders in adult life, such as cardiovascular disease, diabetes, and /or chronic kidney disease. Lower birth weight occurs in numerous undesired intrauterine environments includ...

journal_title：Journal of cardiology

authors： Arima Y,Fukuoka H

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to identify a cut-off value to predict the resolution of incomplete-stent-apposition (ISA) after cobalt-chromium everolimus-eluting stent (CoCr-EES) implantation at early follow-up. BACKGROUND:To date, appropriate stent apposition at the acute period using intracoronary imaging ...

journal_title：Journal of cardiology

authors： Oda H,Itoh T,Sasaki W,Uchimura Y,Taguchi Y,Kaneko K,Sakamoto T,Goto I,Sakuma M,Ishida M,Kikuchi T,Terashita D,Otake H,Morino Y,Shinke T

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Coregistration system of instantaneous wave-free ratio (iFR) pullback and angiography has been developed to enhance benefits of physiology oriented percutaneous coronary intervention (PCI), but its reproducibility has not yet been fully assessed. METHODS AND RESULTS:In 51 coronary arteries from 39 patients ...

journal_title：Journal of cardiology

authors： Higashioka D,Shiono Y,Kubo T,Kitabata H,Nishi T,Terada K,Emori H,Takahata M,Wada T,Shimamura K,Matsuo Y,Ino Y,Tanaka A,Hozumi T,Akasaka T

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Along with the global aging, the number of geriatric patients with acute myocardial infarction (AMI) has been increasing. However, temporal trends in the prevalence and outcomes of geriatric patients with AMI, with a special reference to heart failure (HF) on admission, remain to be elucidated. METHODS:The ...

journal_title：Journal of cardiology

authors： Sato K,Takahashi J,Hao K,Miyata S,Suda A,Shindo T,Ikeda S,Kikuchi Y,Shiroto T,Matsumoto Y,Sakata Y,Shimokawa H

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Although eastern Asian countries are exposed to high levels of air pollution, the impact of long-term exposures to fine particulate matter (PM2.5) air pollution on all-cause and cardiovascular mortality is not well identified. We assessed the relationship between long-term PM2.5 exposure and all-cause/cardio...

journal_title：Journal of cardiology

authors： Kim IS,Yang PS,Lee J,Yu HT,Kim TH,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Anticoagulant therapy is used for preventing cerebral infarction in patients with non-valvular atrial fibrillation (NVAF). However, in clinical practice, many patients with NVAF are not prescribed oral anticoagulants (OACs). In this study, we retrospectively investigated the prescription status of OACs at th...

journal_title：Journal of cardiology

authors： Deguchi I,Osada T,Takao M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Left atrial (LA) size is an established predictor of recurrence after catheter ablation for paroxysmal atrial fibrillation (PAF). We investigated the impact of baseline LA function on recurrence after PAF ablation and compared the predictive values of LA function with those of LA size. METHODS:We retrospect...

journal_title：Journal of cardiology

authors： Oka T,Tanaka K,Ninomiya Y,Hirao Y,Tanaka N,Okada M,Inoue H,Takayasu K,Kitagaki R,Koyama Y,Okamura A,Iwakura K,Sakata Y,Fujii K,Inoue K

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Relative myocardial perfusion imaging can misdiagnose "balanced" ischemia caused by coronary artery disease (CAD). We assessed the feasibility of myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) using dynamic single-photon emission computed tomography (SPECT) with a cadmium-zinc-telluride (...

journal_title：Journal of cardiology

authors： Shiraishi S,Tsuda N,Sakamoto F,Ogasawara K,Tomiguchi S,Tsujita K,Yamashita Y

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Leakage of Ca2+ from the sarcoplasmic reticulum (SR) is a critical contributing factor to heart failure pathophysiology. Therefore, reducing SR Ca2+ leaks may provide significant additive benefits when used in combination with conventional therapies. Dantrolene, a drug routinely used to treat malignant hyper...

journal_title：Journal of cardiology

authors： Kobayashi S,Wakeyama T,Ono S,Ikeda Y,Omura M,Oda T,Hisamatsu Y,Seki K,Satoh A,Hiromoto M,Akashi S,Uchida K,Harada M,Furutani Y,Nakamura Y,Kohno M,Kawamura S,Obayashi M,Michishige H,Yano M

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Ischemia-reperfusion causes endothelial injury and dysfunction in the infarct-related coronary artery (IRA). Using serial assessment of coronary endothelial vasomotor function and left ventriculography (LVG), this study prospectively investigated the clinical impact of endothelial vasomotor dysfunction in th...

journal_title：Journal of cardiology

authors： Obata JE,Horikoshi T,Nakamura T,Kugiyama K

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Optical coherence tomography (OCT) requires intracoronary injection of contrast media to remove blood from the field of view during image acquisition. Contrast injection may cause a temporal increase in intracoronary pressure. The aim of this study was to compare the intracoronary pressure during contrast in...

journal_title：Journal of cardiology

authors： Shimamura K,Kubo T,Ino Y,Shiono Y,Matsuo Y,Kitabata H,Terada K,Emori H,Katayama Y,Khalifa AKM,Takahata M,Wada T,Higashioka D,Kashiwagi M,Kuroi A,Tanaka A,Hozumi T,Akasaka T

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:There have been no reviews regarding intravascular ultrasound (IVUS) catheter entrapment during percutaneous coronary intervention (PCI). This study investigated the incidence, retrieval methods, and outcomes of IVUS catheter stuck within implanted stents. METHODS:Between January 2015 and July 2018, a total...

journal_title：Journal of cardiology

authors： Hiraya D,Sato A,Hoshi T,Sakai S,Watabe H,Ieda M

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Inflammation and oxidative stress play a role in the pathophysiology of chronic heart failure (CHF). Our previous clinical trial, the Bisoprolol Improvement Group for Chronic Heart Failure Treatment Study in Dokkyo Medical University (BRIGHT-D), reported that bisoprolol is superior to carvedilol for myocardi...

journal_title：Journal of cardiology

authors： Toyoda S,Haruyama A,Inami S,Arikawa T,Saito F,Watanabe R,Sakuma M,Abe S,Nakajima T,Tanaka A,Node K,Inoue T

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The use of public-access automated external defibrillators (AEDs) has become common in Japan. To provide a strategy for appropriate public-access AED deployment, we assessed public-access defibrillation (PAD) by laypersons and the outcomes following out-of-hospital cardiac arrest (OHCA) among adult patients ...

journal_title：Journal of cardiology

authors： Kobayashi D,Sado J,Kiyohara K,Kitamura T,Kiguchi T,Nishiyama C,Okabayashi S,Shimamoto T,Matsuyama T,Kawamura T,Iwami T

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Fabry disease is one of the causes of left ventricular hypertrophy (LVH) and can be treated with enzyme replacement therapy or pharmacological chaperone therapy. Late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR) can identify myocardial fibrosis and be used for the stratification in LVH. H...

journal_title：Journal of cardiology

authors： Nojiri A,Anan I,Morimoto S,Kawai M,Sakuma T,Kobayashi M,Kobayashi H,Ida H,Ohashi T,Eto Y,Shibata T,Yoshimura M,Hongo K

更新日期：2020-01-01 00:00:00

abstract：:Atrial fibrillation (AF) causes severe cardiac dysrhythmia among patients with cardiovascular diseases. AF increases the risk of stroke and heart failure and is a growing public health concern. AF is also associated with various disease conditions such as hypertension, coronary artery disease, aging, and diabetes mell...

journal_title：Journal of cardiology

authors： Komal S,Yin JJ,Wang SH,Huang CZ,Tao HL,Dong JZ,Han SN,Zhang LR

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:While physical rehabilitation has been shown to be beneficial and safe for patients suffering from heart failure, data on rehabilitation for hypertrophic cardiomyopathy (HCM) patients are limited. METHODS:Forty-five HCM patients participated in an exercise rehabilitation program. Exercise capacity was measu...

journal_title：Journal of cardiology

authors： Wasserstrum Y,Barbarova I,Lotan D,Kuperstein R,Shechter M,Freimark D,Segal G,Klempfner R,Arad M

更新日期：2019-11-01 00:00:00