听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Stem Cells International期刊下所有文献
  • Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.

    abstract::Dental pulp stem cells (DPSCs) are ideal seed cells for the regeneration of dental tissues. However, DPSC senescence restricts its clinical applications. Metformin (Met), a common prescription drug for type 2 diabetes, is thought to influence the aging process. This study is aimed at determining the effects of metform...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2021/6616240

    authors: Zhang S,Zhang R,Qiao P,Ma X,Lu R,Wang F,Li C,E L,Liu H

    更新日期:2021-01-06 00:00:00

  • Gene Profiles in the Early Stage of Neuronal Differentiation of Mouse Bone Marrow Stromal Cells Induced by Basic Fibroblast Growth Factor.

    abstract::A stably established population of mouse bone marrow stromal cells (BMSCs) with self-renewal and multilineage differentiation potential was expanded in vitro for more than 50 passages. These cells express high levels of mesenchymal stem cell markers and can be differentiated into adipogenic, chondrogenic, and osteogen...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8857057

    authors: Yu L,Hong W,Yang H,Xia YY,Feng Z

    更新日期:2020-12-24 00:00:00

  • Clinical Efficacy and Safety of Stem Cell-Based Therapy in Treating Asherman Syndrome: A System Review and Meta-Analysis.

    abstract::Asherman's Syndrome (AS) is an uncommon, acquired, and refractory gynecological disorder. Current treatment was still limited, and stem cell-based therapy has been proposed as a novel strategy for management of AS. Here, we conducted a meta-analysis of self-controlled clinical trials to assess the effectiveness and sa...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8820538

    authors: Zhao Y,Luo Q,Zhang X,Qin Y,Hao J,Kong D,Wang H,Li G,Gu X,Wang H

    更新日期:2020-12-19 00:00:00

  • The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin Aging.

    abstract:Background:Human dermal fibroblasts (HDFs) are the primary cells in skin and are associated with UVB-induced skin photoaging. Adipose-derived stem cells (ASCs) have been proposed as a treatment for skin aging. The goal of this study was to investigate paracrine mechanisms by which ASCs repair HDFs damage from UVB expos...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8878370

    authors: Qin F,Huang J,Zhang W,Zhang M,Li Z,Si L,Long X,Wang X

    更新日期:2020-12-17 00:00:00

  • Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells.

    abstract::Allogeneic cell-based therapies using adipose tissue-derived stromal cells (ASCs) offer an off-the-shelf alternative to autologous therapy. An underlying assumption is that ASC can modulate the immune response of the recipient. However, in vitro models are required to explore and identify cell interactions and mechani...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8868909

    authors: Juhl M,Follin B,Gad M,Larsen J,Kastrup J,Ekblond A

    更新日期:2020-10-26 00:00:00

  • Antioxidant Effect of Beer Polyphenols and Their Bioavailability in Dental-Derived Stem Cells (D-dSCs) and Human Intestinal Epithelial Lines (Caco-2) Cells.

    abstract::Beer is one of the most consumed alcoholic beverages in the world, rich in chemical compounds of natural origin with high nutritional and biological value. It is made up of water, barley malt, hops, and yeast. The main nutrients are carbohydrates, amino acids, minerals, vitamins, and other compounds such as polyphenol...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8835813

    authors: Di Domenico M,Feola A,Ambrosio P,Pinto F,Galasso G,Zarrelli A,Di Fabio G,Porcelli M,Scacco S,Inchingolo F,Quagliuolo L,Ballini A,Boccellino M

    更新日期:2020-10-10 00:00:00

  • Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells.

    abstract::The lung is a radiosensitive organ, which imposes limits on the therapeutic dose in thoracic radiotherapy. Irradiated alveolar epithelial cells promote radiation-related pneumonitis and fibrosis. However, the role of lung stem cells (LSCs) in the development of radiation-induced lung injury is still unclear. In this s...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/6312053

    authors: Wang LK,Wu TJ,Hong JH,Chen FH,Yu J,Wang CC

    更新日期:2020-09-29 00:00:00

  • The Potential Use of Mesenchymal Stem Cells and Their Derived Exosomes as Immunomodulatory Agents for COVID-19 Patients.

    abstract::A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) causing lethal acute respiratory disease emerged in December 2019. The World Health Organization named this disease "COVID-19" and declared it a pandemic on March 11, 2020. Many studies have shown that mesenchymal stem cells (MSCs) and their exosomes (...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/8835986

    authors: Alzahrani FA,Saadeldin IM,Ahmad A,Kumar D,Azhar EI,Siddiqui AJ,Kurdi B,Sajini A,Alrefaei AF,Jahan S

    更新日期:2020-09-24 00:00:00

  • Myocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells.

    abstract::Previous studies have demonstrated that myocardin-related transcription factor A (MRTF-A) generates a link between the dynamics of the actin cytoskeleton and gene expression with its coregulator, serum response factor (SRF). MRTF-A has also been suggested as a regulator of stem cell differentiation. However, the role ...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8853541

    authors: Hyväri L,Vanhatupa S,Halonen HT,Kääriäinen M,Miettinen S

    更新日期:2020-09-22 00:00:00

  • Epigenetic Regulation in Mesenchymal Stem Cell Aging and Differentiation and Osteoporosis.

    abstract::Mesenchymal stem cells (MSCs) are a reliable source for cell-based regenerative medicine owing to their multipotency and biological functions. However, aging-induced systemic homeostasis disorders in vivo and cell culture passaging in vitro induce a functional decline of MSCs, switching MSCs to a senescent status with...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/8836258

    authors: Wang R,Wang Y,Zhu L,Liu Y,Li W

    更新日期:2020-09-10 00:00:00

  • Peripheral Circulation and Astrocytes Contribute to the MSC-Mediated Increase in IGF-1 Levels in the Infarct Cortex in a dMCAO Rat Model.

    abstract:Materials and Methods:Ischemic brain injury was induced by dMCAO in Sprague-Dawley rats. The transplantation group received MSC infusion 1 h after dMCAO. Expression of IGF-1 in GFAP+ astrocytes, Iba-1+ microglia/macrophages, CD3+ lymphocytes, Ly6C+ monocytes/macrophages, and neutrophil elastase (NE)+ neutrophils was ex...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8853444

    authors: Li X,Yu W,Guan Y,Zou H,Liang Z,Huang M,Zhao R,Zhao C,Ren Z,Chen Z

    更新日期:2020-09-01 00:00:00

  • Corrigendum to "RSP5 Positively Regulates the Osteogenic Differentiation of Mesenchymal Stem Cells by Activating the K63-Linked Ubiquitination of Akt".

    abstract::[This corrects the article DOI: 10.1155/2020/7073805.]. ...

    journal_title:Stem cells international

    pub_type: 已发布勘误

    doi:10.1155/2020/4370849

    authors: Liang C,Liang G,Zheng X,Huang Y,Huang S,Yin D

    更新日期:2020-08-21 00:00:00

  • Molecular Mechanism of Stem Cell Differentiation into Adipocytes and Adipocyte Differentiation of Malignant Tumor.

    abstract::Adipogenesis is the process through which preadipocytes differentiate into adipocytes. During this process, the preadipocytes cease to proliferate, begin to accumulate lipid droplets, and develop morphologic and biochemical characteristics of mature adipocytes. Mesenchymal stem cells (MSCs) are a type of adult stem ce...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/8892300

    authors: Zhang K,Yang X,Zhao Q,Li Z,Fu F,Zhang H,Zheng M,Zhang S

    更新日期:2020-08-12 00:00:00

  • Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells.

    abstract::The mesenchymal stem cells (MSCs) are known as highly plastic stem cells and can differentiate into specialized tissues such as adipose tissue, osseous tissue, muscle tissue, and nervous tissue. The differentiation of mesenchymal stem cells is very important in regenerative medicine. Their differentiation process is r...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/3763069

    authors: Wang F,Li X,Li Z,Wang S,Fan J

    更新日期:2020-08-01 00:00:00

  • Coupled CRC 2D and ALI 3D Cultures Express Receptors of Emerging Viruses and Are More Suitable for the Study of Viral Infections Compared to Conventional Cell Lines.

    abstract::Infections of emerging and reemerging viruses (SARS-CoVs, influenza H1N1, etc.) largely and globally affect human health. Animal models often fail to reflect a physiological status because of species tropism of virus infection. Conventional cell lines are usually genetically and phenotypically different from primary c...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/2421689

    authors: Xia S,Liu J,Yang Y,Wu M,Ye L,Chen S,Zhang T,Zeng Z,Zhang K,Cai K,Long X,Gao W,Fang S,Li H

    更新日期:2020-07-09 00:00:00

  • Epigenetic Clock: DNA Methylation in Aging.

    abstract::Aging, which is accompanied by decreased organ function and increased disease incidence, limits human lifespan and has attracted investigators for thousands of years. In recent decades, with the rapid development of biology, scientists have shown that epigenetic modifications, especially DNA methylation, are key regul...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/1047896

    authors: Jiang S,Guo Y

    更新日期:2020-07-08 00:00:00

  • Cathepsin K Deficiency Impaired Ischemia-Induced Neovascularization in Aged Mice.

    abstract:Background:Aging is a major risk factor for cardiovascular disease. Cysteine protease cathepsin K (CatK) has been implicated in the process of angiogenesis, but the exact roles of individual CatK in vessel formation during aging are poorly understood. Methods and Results:To study the putative role of CatK in ischemia-...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/6938620

    authors: Yue X,Jiang H,Xu Y,Xia M,Cheng XW

    更新日期:2020-06-30 00:00:00

  • Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell-Transplantation after Spinal Cord Injury In Vivo.

    abstract::Stem cell therapy with neural precursor cells (NPCs) has the potential to improve neuroregeneration after spinal cord injury (SCI). Unfortunately, survival and differentiation of transplanted NPCs in the injured spinal cord remains low. Growth factors have been successfully used to improve NPC transplantation in anima...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/5674921

    authors: Younsi A,Zheng G,Scherer M,Riemann L,Zhang H,Tail M,Hatami M,Skutella T,Unterberg A,Zweckberger K

    更新日期:2020-06-17 00:00:00

  • Human Adipose Derived Cells in Two- and Three-Dimensional Cultures: Functional Validation of an In Vitro Fat Construct.

    abstract::Obesity, defined as a body mass index of 30 kg/m2 or above, has increased considerably in incidence and frequency within the United States and globally. Associated comorbidities including cardiovascular disease, type 2 diabetes mellitus, metabolic syndrome, and nonalcoholic fatty liver disease have led to a focus on t...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/4242130

    authors: Bender R,McCarthy M,Brown T,Bukowska J,Smith S,Abbott RD,Kaplan DL,Williams C,Wade JW,Alarcon A,Wu X,Lau F,Gimble JM,Frazier T

    更新日期:2020-06-10 00:00:00

  • RSP5 Positively Regulates the Osteogenic Differentiation of Mesenchymal Stem Cells by Activating the K63-Linked Ubiquitination of Akt.

    abstract::Mesenchymal stem cells (MSCs) are multipotent stem cells that have a strong osteogenic differentiation capacity. However, the molecular mechanism underlying the osteogenic differentiation of MSCs remains largely unknown and thus hinders further development of MSC-based cell therapies for bone repair in the clinic. RSP...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/7073805

    authors: Liang C,Liang G,Zheng X,Huang Y,Huang S,Yin D

    更新日期:2020-04-06 00:00:00

  • Deciduous Dental Pulp Stem Cells for Maxillary Alveolar Reconstruction in Cleft Lip and Palate Patients.

    abstract:Background:To reduce morbidity to cleft patients, new approaches have been developed and here, we report for the first time the use of deciduous dental pulp stem cells (DDPSC) associated with a hydroxyapatite-collagen sponge (Bio-Oss Collagen® 250 mg, Geistlich) for closing alveolar defects during secondary dental erup...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/6234167

    authors: Tanikawa DYS,Pinheiro CCG,Almeida MCA,Oliveira CRGCM,Coudry RA,Rocha DL,Bueno DF

    更新日期:2020-03-12 00:00:00

  • Aging Induced p53/p21 in Genioglossus Muscle Stem Cells and Enhanced Upper Airway Injury.

    abstract::Aging of population brings related social problems, such as muscle attenuation and regeneration barriers with increased aging. Muscle repair and regeneration depend on muscle stem cells (MuSCs). Obstructive sleep apnea (OSA) rises in the aging population. OSA leads to hypoxia and upper airway muscle injury. However, l...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8412598

    authors: Zhu LY,Yu LM,Zhang WH,Deng JJ,Liu SF,Huang W,Zhang MH,Lu YQ,Han XX,Liu YH

    更新日期:2020-03-04 00:00:00

  • Oral Mesenchymal Stem/Progenitor Cells: The Immunomodulatory Masters.

    abstract::Oral mesenchymal stem/progenitor cells (MSCs) are renowned in the field of tissue engineering/regeneration for their multilineage differentiation potential and easy acquisition. These cells encompass the periodontal ligament stem/progenitor cells (PDLSCs), the dental pulp stem/progenitor cells (DPSCs), the stem/progen...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/1327405

    authors: Zhou LL,Liu W,Wu YM,Sun WL,Dörfer CE,Fawzy El-Sayed KM

    更新日期:2020-02-25 00:00:00

  • Intermittent Administration of Parathyroid Hormone Enhances Odonto/Osteogenic Differentiation of Stem Cells from the Apical Papilla via JNK and P38 MAPK Pathways.

    abstract:Objective:Parathyroid hormone (PTH) is considered to be essential during the tooth development. Stem cells from the apical papilla (SCAPs) are responsible for dentine formation. However, the interaction between PTH and SCAPs remains unclear. This study was aimed at investigating the effects of PTH on odonto/osteogenic ...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/5128128

    authors: Pang X,Zhuang Y,Li Z,Jing S,Cai Q,Zhang F,Xue C,Yu J

    更新日期:2020-02-14 00:00:00

  • Screening Genes Promoting Exit from Naive Pluripotency Based on Genome-Scale CRISPR-Cas9 Knockout.

    abstract::Two of the main problems of stem cell and regenerative medicine are the exit of pluripotency and differentiation to functional cells or tissues. The answer to these two problems holds great value in the clinical translation of stem cell as well as regenerative medicine research. Although piling researches have reveale...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/8483035

    authors: Yang B,Kuang J,Wu C,Zhou W,Zhu S,Jiang H,Zhai Z,Wu Y,Peng J,Liu N,Hu H,Ide NM,Chen R,Zhao M,Zhu P

    更新日期:2020-02-03 00:00:00

  • c-Jun Overexpression Accelerates Wound Healing in Diabetic Rats by Human Umbilical Cord-Derived Mesenchymal Stem Cells.

    abstract:Objective:Mesenchymal stem cells (MSCs) are considered a promising therapy for wound healing. Here, we explored the role of c-Jun in diabetic wound healing using human umbilical cord-derived MSCs (hUC-MSCs). Methods:Freshly isolated hUC-MSCs were subjected to extensive in vitro subcultivation. The cell proliferative a...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/7430968

    authors: Yue C,Guo Z,Luo Y,Yuan J,Wan X,Mo Z

    更新日期:2020-01-14 00:00:00

  • MSCs Contribute to the Conversion of Ly6Chigh Monocytes into Ly6Clow Subsets under AMI.

    abstract:Background:Ly6Chigh monocytes are inflammatory cells that accumulate in an infarcted myocardium, and Ly6Clow monocytes are believed to be reparative and curb myocardial remodeling. NR4A1 is a novel target for modulating the inflammatory phenotype of monocytes during atherogenesis. Objectives:We aimed to investigate wh...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2020/2460158

    authors: Lu W,Ma G,Sheng Z,Wang Q,Chen L,Qi J,Shi R,Ji J,Ji Z,Dai Q

    更新日期:2020-01-13 00:00:00

  • Interleukin-1β Enhances Umbilical Cord Mesenchymal Stem Cell Adhesion Ability on Human Umbilical Vein Endothelial Cells via LFA-1/ICAM-1 Interaction.

    abstract::The migration of administered mesenchymal stem cells (MSCs) to sites of injury via the bloodstream has been demonstrated. However, the underlying mechanisms of umbilical cord MSC adhesion to endothelial cells during transendothelial migration are still unclear. In this study, our data showed that IL-1β induced LFA-1 e...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/7267142

    authors: Wu TY,Liang YH,Wu JC,Wang HS

    更新日期:2019-12-27 00:00:00

  • In Vivo Magic Angle Magnetic Resonance Imaging for Cell Tracking in Equine Low-Field MRI.

    abstract::The magic angle effect increases the MRI signal of healthy tendon tissue and could be used for more detailed evaluation of tendon structure. Furthermore, it could support the discrimination of hypointense artefacts induced by contrast agents such as superparamagnetic iron oxide used for cell tracking. However, magic a...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/5670106

    authors: Horstmeier C,Ahrberg AB,Berner D,Burk J,Gittel C,Hillmann A,Offhaus J,Brehm W

    更新日期:2019-12-17 00:00:00

  • Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases.

    abstract::Female infertility impacts the quality of life and well-being of affected individuals and couples. Female reproductive diseases, such as primary ovarian insufficiency, polycystic ovary syndrome, endometriosis, fallopian tube obstruction, and Asherman syndrome, can induce infertility. In recent years, translational med...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/9071720

    authors: Zhao YX,Chen SR,Su PP,Huang FH,Shi YC,Shi QY,Lin S

    更新日期:2019-12-06 00:00:00

  • Systemic Infusion of Expanded CD133+ Cells and Expanded CD133+ Cell-Derived EVs for the Treatment of Ischemic Cardiomyopathy in a Rat Model of AMI.

    abstract::Myocardial infarction is a leading cause of death among all cardiovascular diseases. Cell therapies using a cell population enriched with endothelial progenitor cells (EPCs), expanded CD133+ cells, have promise as a therapeutic option for the treatment of ischemic areas after infarction. Recently, secreted membrane ve...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/4802578

    authors: Angulski ABB,Capriglione LGA,Barchiki F,Brofman P,Stimamiglio MA,Senegaglia AC,Correa A

    更新日期:2019-12-01 00:00:00

  • In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic Heart Disease.

    abstract:Background:While regenerative stem cell therapy for ischemic heart disease has moved into phase 3 studies, little is still known about retention and migration of cell posttransplantation. In human studies, the ability to track transplanted cells has been limited to labeling with radioisotopes and tracking using nuclear...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/2754927

    authors: Mathiasen AB,Qayyum AA,Jørgensen E,Helqvist S,Ekblond A,Ng M,Bhakoo K,Kastrup J

    更新日期:2019-11-14 00:00:00

  • Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis.

    abstract::Mesenchymal stem/stromal cells (MSCs) are known to be useful for treating local bone diseases. However, it is not known if MSCs are effective for treating systemic bone diseases, as the risk for mortality following intravenous MSC administration has hindered research progress. In this study, we compared the safety and...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/4214281

    authors: Agata H,Sumita Y,Hidaka T,Iwatake M,Kagami H,Asahina I

    更新日期:2019-11-12 00:00:00

  • CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.

    abstract::Aged tendon-derived stem/progenitor cells (TSPCs) lead to age-related tendon disorders and impair tendon healing. However, the underlying molecular mechanisms of TSPC aging remain largely unknown. Here, we investigated the role of connective tissue growth factor (CTGF) in TSPC aging. CTGF protein and mRNA levels were ...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/6257537

    authors: Rui YF,Chen MH,Li YJ,Xiao LF,Geng P,Wang P,Xu ZY,Zhang XP,Dai GC

    更新日期:2019-11-11 00:00:00

  • Autologous Stem Cell Transplantation in Multiple Myeloma with Renal Failure: Friend or Foe?

    abstract::Autologous stem cell transplantation (ASCT) is a standard treatment for multiple myeloma (MM), but the clinical response and renal curative effect in MM patients with renal failure (RF) remain controversial. The myeloma kidney disease has different types, and most are due to the direct toxic effects of light chain. Al...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/9401717

    authors: Zhong H,Xie X,Xu G

    更新日期:2019-10-29 00:00:00

  • Mesenchymal Stem Cells Alleviate DHEA-Induced Polycystic Ovary Syndrome (PCOS) by Inhibiting Inflammation in Mice.

    abstract::Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women of reproductive age. Chronic inflammation is considered to be the cause of ovarian dysfunction. Increasing evidence in animal studies and in preliminary clinical trials has demonstrated that MSCs possess immunomodulatory effe...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/9782373

    authors: Xie Q,Xiong X,Xiao N,He K,Chen M,Peng J,Su X,Mei H,Dai Y,Wei D,Lin G,Cheng L

    更新日期:2019-09-12 00:00:00

  • Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties.

    abstract:Aim:Few haematopoietic stem cells (HSCs) injected systemically for therapeutic purposes actually reach sites of injury as the vast majority become entrapped within pulmonary capillaries. One promising approach to maintain circulating HSC numbers would be to separate subpopulations with smaller size and/or greater defor...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/8540706

    authors: Du M,Kavanagh D,Zhang Z,Kalia N

    更新日期:2019-09-05 00:00:00

  • Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors.

    abstract::Chemically induced liver progenitors (CLiPs) have promising applications in liver regenerative medicine. Three-dimensional (3D) structures generated from liver progenitor cells possess wide applications in cell transplantation, disease model, and drug testing. Here, we report on the spontaneous formation of 3D cystic ...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/3975689

    authors: Huang Y,Sakai Y,Hara T,Katsuda T,Ochiya T,Adachi T,Hidaka M,Gu WL,Eguchi S

    更新日期:2019-09-03 00:00:00

  • Local Application of Semaphorin 3A Combined with Adipose-Derived Stem Cell Sheet and Anorganic Bovine Bone Granules Enhances Bone Regeneration in Type 2 Diabetes Mellitus Rats.

    abstract::Bone tissue regeneration is considered to be the optimal solution for bone loss. However, diabetic patients have a greater risk of poor bone healing or bone grafting failure than nondiabetics. The purpose of this study was to investigate the influence of the complexes of an adipose-derived stem cell sheet (ASC sheet) ...

    journal_title:Stem cells international

    pub_type: 杂志文章

    doi:10.1155/2019/2506463

    authors: Xu X,Fang K,Wang L,Liu X,Zhou Y,Song Y

    更新日期:2019-07-31 00:00:00

  • A Review on the Effect of Plant Extract on Mesenchymal Stem Cell Proliferation and Differentiation.

    abstract::Stem cell has immense potential in regenerative cellular therapy. Mesenchymal stem cells (MSCs) can become a potential attractive candidate for therapy due to its remarkable ability of self-renewal and differentiation into three lineages, i.e., ectoderm, mesoderm, and endoderm. Stem cell holds tremendous promises in t...

    journal_title:Stem cells international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/7513404

    authors: Saud B,Malla R,Shrestha K

    更新日期:2019-07-24 00:00:00

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