abstract：:The esophagogastric junction (EGJ) is a complex barrier between the thoracic and abdominal luminal gut compartments, comprised primarily of the lower esophageal sphincter (LES) and crural diaphragm. Although closed at rest, the EGJ relaxes to allow antegrade bolus transit and retrograde venting of air. Abnormal relaxa...

journal_title：Journal of clinical gastroenterology

authors： Rogers BD,Gyawali CP

更新日期：2021-02-01 00:00:00

abstract：GOALS:The authors aimed to compare preperistaltic distal esophageal pressure in patients with esophagogastric junction outflow obstruction (EGJOO) with and without reported dysphagia. BACKGROUND:Manometric EGJOO is characterized by elevated integral relaxation pressure (>15 mm Hg) without achalasia. The nomenclature i...

journal_title：Journal of clinical gastroenterology

authors： Csucska M,Masuda T,Bremner RM,Mittal SK

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:MUC1-glycoprotein is expressed at low levels and in fully glycosylated form on epithelial cells. Inflammation causes MUC1 overexpression and hypoglycosylation. We hypothesized that overexpression of hypoglycosylated MUC1 would be found in postoperative Crohn's disease (CD) recurrence and could be considered ...

journal_title：Journal of clinical gastroenterology

authors： Hashash JG,Beatty PL,Critelli K,Hartman DJ,Regueiro M,Tamim H,Regueiro MD,Binion DG,Finn OJ

更新日期：2021-02-01 00:00:00

abstract：GOALS:We performed a systematic review with meta-analysis to examine the efficacy and safety of oral fecal microbiota transplantation (FMT) capsules for recurrent Clostridioides difficile infection (rCDI). BACKGROUND:FMT through colonoscopy is established as effective and safe in treating multiple recurrences of CDI, ...

journal_title：Journal of clinical gastroenterology

authors： Du C,Luo Y,Walsh S,Grinspan A

更新日期：2021-01-19 00:00:00

abstract：:Since the first fiberoptic instruments, gastrointestinal endoscopy has shaped the field of gastroenterology and is now a key diagnostic and therapeutic tool. Compared with the initial fiberoptic endoscopes state-of-the-art optical chips (or charge-coupled device technology) allowed a quantum leap in image quality. Des...

journal_title：Journal of clinical gastroenterology

authors： Holtmann GJ,Huelsen A,Shah A,Hourigan LF,Morrison M

更新日期：2021-01-01 00:00:00

abstract：GOALS:We investigated the distribution of pathogens on stool gastrointestinal (GI) polymerase chain reaction (PCR) testing in those who subsequently developed inflammatory bowel disease (IBD). BACKGROUND:Infectious gastroenteritis has been associated with later development of IBD. STUDY:This retrospective study inclu...

journal_title：Journal of clinical gastroenterology

authors： Varma S,Green PH,Krishnareddy S

更新日期：2020-11-25 00:00:00

abstract：GOAL:The goal of this study was to evaluate the inpatient mortality risk among geriatric patients with inflammatory bowel disease (IBD). BACKGROUND:The challenges of caring for elderly patients with IBD will increase with the aging of the US population. Given the complications of hospitalization, we set to examine if ...

journal_title：Journal of clinical gastroenterology

authors： Schwartz J,Stein DJ,Lipcsey M,Li B,Feuerstein JD

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Quantitative information is scarce with regard to guidelines for currently prescribed medications for constipation. Furthermore, these guidelines do not reflect the differences in the number of bowel movements caused by each drug. GOALS:In this study, we used a model-based meta-analysis to quantitatively es...

journal_title：Journal of clinical gastroenterology

authors： Zhang Y,Yin F,Xu L,Li YF,Chen JC,Liu HX,Zheng QS,Li LJ

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Over 2.1 million individuals in the United Stats have cirrhosis, including 513,000 with decompensated cirrhosis. Hospitals with high safety-net burden disproportionately serve ethnic minorities and have reported worse outcomes in surgical literature. No studies to date have evaluated whether hospital safety-...

journal_title：Journal of clinical gastroenterology

authors： Wong RJ,Hirode G

更新日期：2020-10-29 00:00:00

abstract：GOALS:To test the hypothesis that water exchange (WE), when compared with carbon dioxide (CO2) insufflation, significantly reduces the right colon adenoma miss rate (rAMR) in a blinded randomized controlled trial with cap-assisted colonoscopy. BACKGROUND:The unblinded consecutive group observational data showed that W...

journal_title：Journal of clinical gastroenterology

authors： Cheng CL,Kuo YL,Hsieh YH,Tang JH,Leung FW

更新日期：2020-10-16 00:00:00

abstract：GOALS:Assess neoplasia and polypectomy-related adverse event (AE) rates in gastric hyperplastic polyps (GHPs). BACKGROUND:GHPs carry a risk of neoplastic transformation. The rate of neoplastic transformation and the risk of polypectomy-related bleeding are unclear in the West, as data are derived from Asian or small s...

journal_title：Journal of clinical gastroenterology

authors： Bar N,Kinaani F,Sperber AD,Amir-Barak H,Dekel R

更新日期：2020-10-13 00:00:00

abstract：BACKGROUND & AIMS:Cyclic vomiting syndrome (CVS) is characterized by episodes of nausea and vomiting separated by symptom-free intervals. Rome IV guidelines have now distinguished CVS from other disorders such as cannabinoid hyperemesis. The pathogenesis of CVS, however, is poorly understood. Limited data exist on gast...

journal_title：Journal of clinical gastroenterology

authors： Kamal A,Sarvepalli S,Selvakumar P,Lopez R,Radhakrishnan K,Gabbard S

更新日期：2020-10-01 00:00:00

abstract：:Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, cannabinoid receptors 1 and 2, are found on cells of various tissues, with...

journal_title：Journal of clinical gastroenterology

authors： Unal E,Anderson B,Helber A,Marks JH

更新日期：2020-10-01 00:00:00

abstract：GOAL:The goal of this study was to determine disparities in liver cancer surveillance among people with disabilities is the goal of this study. BACKGROUND:Using the linked administrative database in Korea, we sought to investigate (1) whether there are disparities in liver cancer surveillance according to degree and t...

journal_title：Journal of clinical gastroenterology

authors： Seo JY,Shin DW,Yu SJ,Jung JH,Han K,Cho IY,Kim SY,Choi KS,Park JH,Park JH,Kawachi I

更新日期：2020-09-04 00:00:00

abstract：BACKGROUND:An association between Helicobacter pylori infection and colorectal neoplasia has been reported in cross-sectional studies. GOALS:We examined the association between H. pylori infection and the development of advanced colorectal neoplasia (AN) in a screening cohort. STUDY:We identified 3753 adults, who und...

journal_title：Journal of clinical gastroenterology

authors： Ryoo SK,Kim TJ,Kim ER,Hong SN,Kim YH,Chang DK

更新日期：2020-09-01 00:00:00

abstract：:There are >1.5 billion people with chronic liver disease worldwide, causing liver diseases to be a significant global health issue. Diffuse parenchymal liver diseases, including hepatic steatosis, fibrosis, metabolic diseases, and hepatitis cause chronic liver injury and may progress to fibrosis and eventually hepatoc...

journal_title：Journal of clinical gastroenterology

authors： Ghadimi M,Habibabadi RR,Hazhirkarzar B,Shaghaghi M,Ameli S,Khoshpouri P,Ghasabeh MA,Gurakar A,Pawlik TM,Kamel IR

更新日期：2020-09-01 00:00:00

abstract：GOALS:The study aimed to compare the level and characteristics of disease-related knowledge of patients with inflammatory bowel disease (IBD) between the West and the East using an international version of a questionnaire regarding knowledge of inflammatory bowel disease (IBD-KNOW). BACKGROUND:The authors recently dev...

journal_title：Journal of clinical gastroenterology

authors： Kim JY,Yoon H,Hwang JS,Yang SK,Park SH,Loftus EV Jr

更新日期：2020-09-01 00:00:00

abstract：GOALS:To evaluate the diagnostic yield of colonoscopy and esophagogastroduodenoscopy with biopsies and to identify predictors of positive colonic histology in patients with chronic diarrhea. BACKGROUND:Colonoscopy with biopsies is performed in chronic diarrhea with negative initial work-up. STUDY:We reviewed electron...

journal_title：Journal of clinical gastroenterology

authors： Atieh J,Chedid V,Khoshbin K,Kane S,Camilleri M

更新日期：2020-08-21 00:00:00

abstract：:In the current COVID-19 pandemic, there has been concern regarding the use of ibuprofen and other nonsteroidal anti-inflammatory agents by COVID-19 infected patients. Aminosalicylates (5-ASAs) are structurally similar and have anti-inflammatory functions that resemble those of nonsteroidal anti-inflammatory agents. Si...

journal_title：Journal of clinical gastroenterology

authors： Ehrenpreis ED,Kruchko DH

更新日期：2020-08-01 00:00:00

abstract：GOALS:The authors aimed to characterize older adults' intentions for future surveillance colonoscopy, knowledge of polyps, and predictors of colonoscopy plans. BACKGROUND:Guidelines recommend that the decision to continue or stop surveillance colonoscopy in older adults with colon polyps be "individualized." Although ...

journal_title：Journal of clinical gastroenterology

authors： Calderwood AH,Carter C,Durand MA,O'Connor S,Boardman M

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND AND AIMS:Spastic esophageal motility disorders (SEMD) are a rare group of motility disorders including type III achalasia, distal esophageal spasm (DES), and Jackhammer esophagus (JHE). Limited data suggest that per-oral endoscopic myotomy (POEM) may be effective in these disorders. In this study, we aimed t...

journal_title：Journal of clinical gastroenterology

authors： Nabi Z,Chavan R,Ramchandani M,Basha J,Jagtap N,Karyampudi A,Darisetty S,Tandan M,Goud R,Rao GV,Reddy DN

更新日期：2020-07-10 00:00:00

abstract：GOAL:The goal of this study was to assess the relationship between pretransplant measures of reflux and longer-term outcomes of chronic allograft rejection in lung transplant recipients. BACKGROUND:Bronchiolitis obliterans syndrome (BOS) is a primary measure of morbidity and mortality following lung transplantation, a...

journal_title：Journal of clinical gastroenterology

authors： Lo WK,Moniodis A,Goldberg HJ,Feldman N,Chan WW

更新日期：2020-07-01 00:00:00

abstract：:Various esophageal functional abnormalities have been described in patients with Barrett's esophagus (BE). A significantly higher esophageal acid exposure especially in the supine position has been documented in BE, as compared with the other gastroesophageal reflux disease phenotypes. In addition, weakly acidic reflu...

journal_title：Journal of clinical gastroenterology

authors： Fass R,Teramoto O,Kurin M,Khalessi A,Kitayama Y,Shibli F

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Human enteric antimicrobial peptides composed predominantly of human enteric α-defensins (HD5 and HD6) are important in the mucosal antimicrobial barrier. Previous studies have identified that genetic variations at rs2066844, rs2066845, rs2066847 are associated with diminished enteric α-defensins in...

journal_title：Journal of clinical gastroenterology

authors： Deng Q,Tan G,Deng F,Zhi F

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Endoscopic ultrasound (EUS)-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE) is a minimally invasive option for pancreaticobiliary access in patients with Roux-en-Y anatomy. The procedure involves creating a fistulous tract between the remnant stomach or jejunum and the bypassed ...

journal_title：Journal of clinical gastroenterology

authors： Tyberg A,Kedia P,Tawadros A,Tarnasky PR,Gaidhane M,Nieto J,Kahaleh M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The cure for hepatitis B is defined as the hepatitis B surface antigen (HBsAg) seroclearance and/or seroconversion. Predictors of spontaneous seroconversion are not well described. The objective of this study is to identify predictors of spontaneous HBsAg seroconversion from community practice. METHODS:We p...

journal_title：Journal of clinical gastroenterology

authors： Wu CF,Fong TM,Wu SS,Saab S

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The epidemiology of meningitis is unknown in inflammatory bowel disease (IBD) patients. GOALS:We aimed to determine the incidence of and risk factors for meningitis in IBD patients. STUDY:We conducted a retrospective cohort and nested case-control study in the Quintiles IMS Legacy PharMetrics Adjudicated C...

journal_title：Journal of clinical gastroenterology

authors： Kochar B,Jiang Y,Long MD

更新日期：2020-05-29 00:00:00

abstract：GOAL:The goal of this study was to investigate the relationship between Helicobacter pylori (H. pylori) infection and short-segment and long-segment Barrett's esophagus (SSBE and LSBE). BACKGROUND:H. pylori infection is reported to be inversely associated with Barrett's esophagus (BE) in western countries. However, th...

journal_title：Journal of clinical gastroenterology

authors： Usui G,Sato H,Shinozaki T,Jinno T,Fujibayashi K,Ishii K,Horiuchi H,Morikawa T,Gunji T,Matsuhashi N

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:There was some ambiguity in the recent guidelines on the use of capsule endoscopy (CE) in cases of iron deficiency anemia (IDA). GOAL:We aimed to examine the yield of CE in diagnosing the cause of IDA and to define clinical parameters that predict higher diagnostic yields. MATERIALS AND METHODS:A total of ...

journal_title：Journal of clinical gastroenterology

authors： Stone J,Grover K,Bernstein CN

更新日期：2020-05-01 00:00:00

abstract：:Gastrointestinal (GI) disturbances are common during training and competition, especially among endurance athletes. Historically, little attention has been paid to the psychobiological etiology of GI problems in sport. The aim of this review is to: (1) provide a physiological overview of how psychological stress and a...

journal_title：Journal of clinical gastroenterology

authors： Wilson PB

更新日期：2020-04-01 00:00:00

abstract：GOALS:The goal of this study was to elucidate the most important predictors for elevation of gastrin in patients on long-term PPI therapy through analysis of data from 2 published studies in Icelandic patients with erosive GERD. BACKGROUND:Gastrin elevation is a known but variable consequence of proton pump inhibitor ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Lund SH,Gizurarson S,Metz DC,Björnsson ES

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND AIM:Accumulating clinical and epidemiologic evidence indicates that nonalcoholic fatty liver disease (NAFLD) is not only associated with liver-related morbidity and mortality, but also with a greater risk of coronary heart disease (CHD). However, there is currently no diagnostic parameter for NAFLD that ...

journal_title：Journal of clinical gastroenterology

authors： Song Y,Dang Y,Wang P,Tian G,Ruan L

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Visual characteristics seen during digital single-operator cholangioscopy (DSOC) have not been validated. The aim of this 2-phase study was to define terminology by consensus for the visual diagnosis of biliary lesions to develop a model for optimization of the diagnostic performance of DSOC. MATERIALS AND ...

journal_title：Journal of clinical gastroenterology

authors： Sethi A,Tyberg A,Slivka A,Adler DG,Desai AP,Sejpal DV,Pleskow DK,Bertani H,Gan SI,Shah R,Arnelo U,Tarnasky PR,Banerjee S,Itoi T,Moon JH,Kim DC,Gaidhane M,Raijman I,Peterson BT,Gress FG,Kahaleh M

更新日期：2020-02-07 00:00:00

abstract：GOALS:We aimed to establish the epidemiological characteristics and documentation of diagnostic workup for gastroparesis (GP). BACKGROUND:No study has used a national database to evaluate the prevalence, demographics, and associated comorbid conditions of GP, and document rates of proper diagnosis. MATERIALS AND METH...

journal_title：Journal of clinical gastroenterology

authors： Syed AR,Wolfe MM,Calles-Escandon J

更新日期：2020-01-01 00:00:00

abstract：GOALS:We compare bowel cleanliness in patients taking same-day versus split-dose 4-L polyethylene glycol laxative for afternoon colonoscopy. Secondary objectives included patient satisfaction, adverse effects and patient tolerability. BACKGROUND:Afternoon colonoscopies have been associated with inadequate bowel prepar...

journal_title：Journal of clinical gastroenterology

authors： Castro FJ,Al-Khairi B,Singh H,Mohameden M,Tandon K,Lopez R

更新日期：2019-11-01 00:00:00

abstract：GOALS:This study aimed to characterize the impact of stool consistency on patient-reported bowel movement (BM) satisfaction in patients with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation, with a focus on linaclotide. BACKGROUND:As new medications for constipation become availabl...

journal_title：Journal of clinical gastroenterology

authors： Taylor DCA,Abel JL,Doshi JA,Martin C,Goolsby Hunter A,Essoi B,Korrer S,Reasner DS,Carson RT,Chey WD

更新日期：2019-11-01 00:00:00

abstract：GOAL:To evaluate the effect of yogurt supplemented with probiotic bacteria on the prevention of antibiotic-associated diarrhea (AAD) in hospitalized patients. BACKGROUND:Diarrhea following antibiotic administration is a frequent clinical problem. The usefulness of probiotics for the prevention of AAD in the hospitaliz...

journal_title：Journal of clinical gastroenterology

authors： Velasco M,Requena T,Delgado-Iribarren A,Peláez C,Guijarro C

更新日期：2019-11-01 00:00:00

abstract：GOAL:To evaluate the impact of Karnofsky Performance Status score (KPSS) at the time of liver transplantation (LT) on post-LT survival. BACKGROUND:While the Model for End-Stage Liver Disease (MELD) score is used to prioritize individuals for LT, it does not specifically incorporate functional status into patient asses...

journal_title：Journal of clinical gastroenterology

authors： McCabe P,Gish RG,Cheung R,Wong RJ

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Informed consent is a vital preprocedural step for endoscopy but there are substantial variations in its delivery. We therefore sought to assess a multifaceted intervention to improve the consent process. METHODS:Gastroenterologists at a tertiary center were educated on the recommended components o...

journal_title：Journal of clinical gastroenterology

authors： Fudman DI,Papamichael K,Roemi L,Rao V,Falchuk KR,Leffler DA,Feuerstein JD

更新日期：2019-09-01 00:00:00

abstract：GOALS:We aimed to ascertain whether waist circumference (WC) is associated with risk of colorectal neoplasia (CRN), independent of body mass index (BMI). BACKGROUND:Although several studies have reported the association between abdominal obesity, measured by WC, and CRN, it remains unclear whether their association is...

journal_title：Journal of clinical gastroenterology

authors： Kim NH,Jung YS,Park JH,Park DI,Sohn CI

更新日期：2019-08-01 00:00:00