abstract：OBJECTIVE:The study aimed to evaluate the effect of internal silver coating as a countermeasure to crestal bone loss around implants with or without multiple abutment disconnections/reconnections. MATERIALS AND METHODS:Following tooth extraction, 48 implants with connected healing abutments (24 implants internally coa...

journal_title：Clinical oral investigations

authors： Fickl S,Stappert CFJ,Kohles SS

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:For well-defined deep (> 2/3 dentin extension) carious lesions, selective (SE) or stepwise (SW) carious tissue removals have been recommended, while there is limited comparative evidence for both. We compared SE and SW over 24 months in a randomized controlled trial. METHODS:A two-arm superiority trial was ...

journal_title：Clinical oral investigations

authors： Elhennawy K,Finke C,Paris S,Reda S,Jost-Brinkmann PG,Schwendicke F

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:This work aimed to study the role of inflammation in medication-related osteonecrosis of the jaw (MRONJ) in rats with focus on Wnt signaling. METHODS:A total of 36 female Wistar rats (12 weeks ± 200 g) were divided into 2 groups (n = 6) in 3 experiments: saline (SAL) and zoledronic acid (ZOL). For MRONJ indu...

journal_title：Clinical oral investigations

authors： de Sousa Ferreira VC,Lopes AP,Alves NM,Sousa FRN,Pereira KMA,Gondim DV,Girão VCC,Leitão RFC,Goes P

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:SLC22A4/5 single nucleotide polymorphisms (SNPs) have been reported to affect inflammatory diseases. We report the relationship of these polymorphisms with adiposity and tooth loss as elucidated in a 10-year follow-up study. METHODS:Participants of the Study of Health in Pomerania (SHIP, N = 4105) were genot...

journal_title：Clinical oral investigations

authors： Meisel P,Pagels S,Grube M,Jedlitschky G,Völzke H,Kocher T

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The aim of this systematic review and meta-analysis (SRM) was to assess the postoperative pain (PP) after non-surgical endodontic retreatment (NSER) in a one visit compared to multiple visits. The PICO question used was "Does NSER in patients with unsatisfactory endodontic treatment in a one-visit visit have...

journal_title：Clinical oral investigations

authors： Nunes GP,Delbem ACB,Gomes JML,Lemos CAA,Pellizzer EP

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:To date, scarce evidence exists around the application of subgingival air polishing during treatment of severe periodontitis. The aim of this study was to evaluate the benefits of subgingival air polishing during non-surgical treatment of deep bleeding pockets in stages III-IV periodontitis patients MATERIAL...

journal_title：Clinical oral investigations

authors： Mensi M,Scotti E,Sordillo A,Calza S,Guarnelli ME,Fabbri C,Farina R,Trombelli L

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:The aim of the meta-analysis was to clarify the efficacy of non-surgical periodontal treatment (NSPT) in improving rheumatoid arthritis (RA) disease activity. METHODS:A systematic literature search was conducted using the PubMed, Embase, and Cochrane databases up to October 2020. A total of nine studies wer...

journal_title：Clinical oral investigations

authors： Sun J,Zheng Y,Bian X,Ge H,Wang J,Zhang Z

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVES:Aberrant growth of the maxillomandibular complex in patients with cleft lip and/or palate (CL/P) can be managed with dentofacial orthopaedics. However, no consensus has been reached regarding timing and evolution of the maturational stages. Therefore, the aim of this study is to determine if patients with CL...

journal_title：Clinical oral investigations

authors： Thierens LAM,Manalili L,De Roo N,Verdonck A,De Llano-Pérula MC,De Pauw GAM

更新日期：2021-01-23 00:00:00

abstract：OBJECTIVES:This study aimed to estimate the dental age (DA) using the London Atlas, Willems, and Nolla methods and to compare their accuracies. METHODS:The DA was estimated using the aforementioned methods on panoramic radiograms of a total of 919 Eastern Turkish patients aged 6-14 years, of whom 459 were female and 4...

journal_title：Clinical oral investigations

authors： Koç A,Özlek E,Öner Talmaç AG

更新日期：2021-01-18 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess whether alveolar ridge preservation (ARP) can reduce the need of ridge augmentation at posterior tooth sites. MATERIAL AND METHODS:This study enrolled patients who received dental implants at posterior tooth sites during 2013-2019. Demographic data and dental treatment hi...

journal_title：Clinical oral investigations

authors： Hu KF,Lin YC,Huang YT,Chou YH

更新日期：2021-01-11 00:00:00

abstract：OBJECTIVES:We aimed to determine the immunolocalization patterns of the interleukin (IL)-6 signaling complex in epithelialized and non-epithelialized apical lesions of endodontic origin (ALEOs). MATERIALS AND METHODS:Epithelialized (n = 8) and non-epithelialized (n = 7) ALEOs were obtained from teeth with indication o...

journal_title：Clinical oral investigations

authors： Schweitzer C,Garrido M,Paredes R,Stoore C,Reyes M,Bologna-Molina R,Fernández A,Hernández Rios M

更新日期：2021-01-07 00:00:00

abstract：OBJECTIVES:To evaluate, longitudinally, the impacts of orthognathic surgery in patients with skeletal class II malocclusion on oral health-related quality of life (OHRQoL), temporomandibular disorders (TMD) and psychological symptoms. MATERIALS AND METHODS:Forty-three patients with skeletal class II malocclusion who w...

journal_title：Clinical oral investigations

authors： Bergamaschi IP,Cavalcante RC,Fanderuff M,Gerber JT,Petinati MFP,Sebastiani AM,da Costa DJ,Scariot R

更新日期：2021-01-07 00:00:00

abstract：OBJECTIVES:The purpose of this experimental in vivo investigation was to evaluate the influence of modifying the implant surface by adding a monolayer of multi-phosphonate molecules on the development of experimental peri-implantitis. MATERIAL AND METHODS:Eight beagle dogs received 5 tests and 5 control implants each ...

journal_title：Clinical oral investigations

authors： Sanz-Esporrin J,Di Raimondo R,Pla R,Luengo F,Vignoletti F,Núñez J,Antonoglou GJ,Blanco J,Sanz M

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVE:Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CDKN2B, RPSAP52, GPR45 HHEX, IL18, and RUNX2 genes associated with type 2 diabetes mellitus (T2DM) and/or periodontitis (P) in diverse populations, and we sought to evaluate them as ...

journal_title：Clinical oral investigations

authors： Cirelli T,Nepomuceno R,Goveia JM,Orrico SRP,Cirelli JA,Theodoro LH,Barros SP,Scarel-Caminaga RM

更新日期：2021-01-03 00:00:00

abstract：OBJECTIVES:The purpose of this study was to assess the clinical and radiographic outcome of root-end microsurgery using a premixed fast-set calcium silicate putty as root-end filling material in human teeth. MATERIALS AND METHODS:This study included 50 teeth in 35 patients, whose ages ranged from 16 to 69 years. After...

journal_title：Clinical oral investigations

authors： Taha NA,Aboyounes FB,Tamimi ZZ

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The present study aimed to identify and quantify the elution of monomers of five different resin-based CAD/CAM blocks (RCBs) using HPLC. METHODS:Five different RCBs were used in the study: GC Cerasmart (CS), Voco Grandio blocs (GR), 3M Lava Ultimate (LU), Shofu Block (SB), and Vita Enamic (VE). Fifteen sampl...

journal_title：Clinical oral investigations

authors： Barutcigil K,Dündar A,Batmaz SG,Yıldırım K,Barutçugil Ç

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:This study aimed to survey dentists in Germany to identify their favored materials for the fabrication of tooth-supported single crowns (SCs) depending on the location of the abutment teeth and the preparation margin. MATERIALS AND METHODS:The survey included questions regarding demographic characteristics ...

journal_title：Clinical oral investigations

authors： Rauch A,Schrock A,Schierz O,Hahnel S

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate changes in saliva concentration of the inflammatory marker MRP-8/14 and the presence of some periodontitis-associated bacteria in patients with mixed dentition treated with a rigid acrylic, bonded maxillary expander. METHODS:Fifteen patients in mixed dentition treate...

journal_title：Clinical oral investigations

authors： Nemec M,Mittinger N,Bertl M,Liu E,Jonke E,Andrukhov O,Rausch-Fan X

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVE:This study aimed to evaluate the effects of chronic consumption of cachaça, a Brazilian beverage containing alcohol, on submandibular glands (SM) of rats by using histomorphometric and biochemical parameters. MATERIALS AND METHODS:Twenty-four male rats (40 days of age) were assigned into the following four g...

journal_title：Clinical oral investigations

authors： Dal Prá KJ,de Fatima Moraes da Silva A,Chaves-Neto AH,Soubhia AMP

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:To explore whether a computed tomography (CT) examination of the head and neck region induces biological damage and whether the damage was correlated with the radiation dose. MATERIALS AND METHODS:Peripheral blood was taken from 33 individuals who received head and neck CT examinations. Blood samples were d...

journal_title：Clinical oral investigations

authors： Yang P,Wang S,Liu D,Zhao H,Li G

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:Pain and trismus are the most common postoperative complications following a surgical removal of the lower third molar. This randomized, double-blind, placebo-controlled clinical trial evaluated the effect of orally administrated magnesium on postoperative pain and trismus after surgical removal of the lower...

journal_title：Clinical oral investigations

authors： Jerkovic D,Tadin A,Gavic L,Vladislavic NZ,Grgic N,Macan D

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:This study evaluated the danger zone (DZ) in mesial roots of mandibular molars and the correlation between anatomical references of the DZ and some anatomical landmarks including tooth/root length, depth of mesial and distal grooves, and inter-canal orifices distance. MATERIAL AND METHODS:Twenty-eight mesia...

journal_title：Clinical oral investigations

authors： De-Deus G,Rodrigues EA,Lee JK,Kim J,da Silva EJNL,Belladonna FG,Cavalcante DM,Simões-Carvalho M,Oliveira DDS,Versiani MA,Souza EM

更新日期：2020-11-24 00:00:00

abstract：OBJECTIVES:Detecting bacterial activity is considered a promising approach to monitor shifts from symbiosis to dysbiosis in oral microbiome. The present study aimed at investigating both the relative bacterial activity and the lactate dehydrogenase (ldh) gene expression of caries-associated bacteria in a site-specific ...

journal_title：Clinical oral investigations

authors： Walther C,Zumbülte S,Faerber CM,Wierichs RJ,Meyer-Lueckel H,Conrads G,Henne K,Esteves-Oliveira M

更新日期：2020-11-23 00:00:00

abstract：OBJECTIVES:An optimized oral health-related section and a video training were developed and validated for the interRAI suite of instruments. The latter is completed by professional non-dental caregivers and used in more than 40 countries to assess care needs of older adults. METHODS:The optimized oral health-related s...

journal_title：Clinical oral investigations

authors： Krausch-Hofmann S,Tran TD,Janssens B,Declerck D,Lesaffre E,de Almeida Mello J,Declercq A,De Lepeleire J,Duyck J

更新日期：2020-11-16 00:00:00

abstract：OBJECTIVES:This animal study was conducted to evaluate the osteocyte index in the peri-implant bone around immediately restored implants under static lateral overload. MATERIAL AND METHODS:Seven mongrel dogs received three implants on each side of the mandible. Forty-two implants were distributed into three groups (14...

journal_title：Clinical oral investigations

authors： de Calais CD,Bordin D,Piattelli A,Iezzi G,Negretto A,Shibli JA

更新日期：2020-11-05 00:00:00

abstract：OBJECTIVE:Our aim was to assess the anti-biofilm ability of previously unverified individual D-amino acids (DAAs), to produce plasma polymer encapsulated DAAs (PPEDAAs), to measure the shell thickness and subsequent release of DAAs, and to assess the effects of PPEDAAs on Enterococcus faecalis biofilms. MATERIALS AND ...

journal_title：Clinical oral investigations

authors： Khider D,Rossi-Fedele G,Fitzsimmons T,Vasilev K,Zilm PS

更新日期：2020-11-02 00:00:00

abstract：OBJECTIVES:This in situ study aims to evaluate the effects of chlorhexidine (CHX) mouth rinsing on biofilm formation and moreover on the disruption of existing mature dental biofilms. METHODS:Biofilms were formed in situ by five volunteers on bovine enamel specimens fixed to individual acrylic splints. For biofilm for...

journal_title：Clinical oral investigations

authors： Martínez-Hernández M,Reda B,Hannig M

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:We evaluated the effects of low-level laser therapy (LLLT) using an infrared laser (IRL) and a red laser (RL) on the pulp of molar teeth in rats after dental bleaching to assess inflammation, collagen fiber maturation, and tertiary dentin formation. MATERIALS AND METHODS:Eighty Wistar rats (Rattus norvegicu...

journal_title：Clinical oral investigations

authors： Terayama AM,Benetti F,de Araújo Lopes JM,Barbosa JG,Silva IJP,Sivieri-Araújo G,Briso ALF,Cintra LTA

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To assess the internal and external morphologies of the mesiobuccal (MB) root of maxillary molars presenting a third root canal (MB3), using micro-computed tomography (micro-CT). MATERIAL AND METHODS:Two-hundred and sixty-five extracted maxillary first and second molars with different root configurations we...

journal_title：Clinical oral investigations

authors： Ordinola-Zapata R,Martins JNR,Plascencia H,Versiani MA,Bramante CM

更新日期：2020-11-01 00:00:00

abstract：:In the original version of this article, the following were noted for correction. ...

journal_title：Clinical oral investigations

authors： Sreenivasan PK,Kakarla VVP,Sharda S,Setty Y

更新日期：2020-10-26 00:00:00

abstract：OBJECTIVES:There is an increasing number of oral squamous cell carcinoma (OSCC) associated with HPV-16. However, p16 expression by immunohistochemistry as the current gold standard for a surrogate marker for virus infection reveals unsatisfying diagnostic accuracy. The aim of this study was to investigate a new rapid t...

journal_title：Clinical oral investigations

authors： Blatt S,Pabst A,Zimmer S,Walter C,Al-Nawas B,Krüger M

更新日期：2020-10-23 00:00:00

abstract：OBJECTIVES:The purpose of this randomized controlled trial was to compare the 24-month success rates of indirect pulp treatment (IPT) and iRoot BP Plus pulpotomy of primary molars with extremely deep caries. MATERIALS AND METHODS:Generally healthy children aged 3-7 years requiring general anesthesia for treating prima...

journal_title：Clinical oral investigations

authors： Chen X,Zhang H,Zhong J,Yan W,Lin B,Ding M,Xue S,Xia B

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVES:To assess the potential influence of systemic antibiotic administration on the healing of periodontal intrabony defects treated with deproteinized bovine bone mineral (DBBM) and collagen membrane. MATERIALS AND METHODS:Forty-one intrabony defects were treated by means of DBBM and collagen membrane (GTR). Po...

journal_title：Clinical oral investigations

authors： Pietruska M,Dolińska E,Milewski R,Sculean A

更新日期：2020-10-13 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate the antimicrobial efficacy of antiseptics in saliva-derived microcosm biofilms, and to examine phenotypic adaption of bacteria upon repeated exposure to sub-inhibitory antiseptic concentrations. METHODS:Saliva-derived biofilms were formed mimicking caries- or gingi...

journal_title：Clinical oral investigations

authors： Schwarz SR,Hirsch S,Hiergeist A,Kirschneck C,Muehler D,Hiller KA,Maisch T,Al-Ahmad A,Gessner A,Buchalla W,Cieplik F

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVE:The objective of this in vitro study was to investigate fracture load, fracture types, and impact of chewing simulation of human molars restored with 3D printed indirect polyetheretherketone (PEEK) inlays and compare these with milled indirect PEEK inlays, direct resin composite fillings, and sound teeth. MA...

journal_title：Clinical oral investigations

authors： Prechtel A,Stawarczyk B,Hickel R,Edelhoff D,Reymus M

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The present study evaluated the cellular tissue reaction of two equine-derived collagen hemostatic sponges (E-CHS), which differed in thickness after pressing, over 30 days in vivo. The inflammatory response during physiological wound healing in sham-operated animals was used as control group. MATERIAL AND ...

journal_title：Clinical oral investigations

authors： Herrera-Vizcaíno C,Al-Maawi S,Sader R,Kirkpatrick CJ,Choukroun J,Ghanaati S

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Ex-vivo evaluation of the detectability of vertical root fractures (VRFs) using digital subtraction radiography (DSR) and conventional digital periapical radiography (CDPR); investigation of the effect of root canal filling, x-ray angulation, and thickness of the VRF in the diagnostic accuracy. MATERIALS AND...

journal_title：Clinical oral investigations

authors： Kapralos V,Koutroulis A,Irinakis E,Kouros P,Lyroudia K,Pitas I,Mikrogeorgis G

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:This study was established to investigate whether the chemokines CXCL1, CCL2, and CCL5 are produced in periodontal cells and tissues and, if so, whether their levels are regulated by microbial and/or mechanical signals. MATERIALS AND METHODS:The chemokine expression and protein levels in gingival biopsies f...

journal_title：Clinical oral investigations

authors： Rath-Deschner B,Memmert S,Damanaki A,Nokhbehsaim M,Eick S,Cirelli JA,Götz W,Deschner J,Jäger A,Nogueira AVB

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate through a systematic review the extraction of third molars as a risk factor for temporomandibular disorders (TMDs). TYPES OF STUDIES REVIEWED:Randomized and nonrandomized controlled clinical trials where patients underwent third molar extraction and with qualitative eva...

journal_title：Clinical oral investigations

authors： Damasceno YSS,Espinosa DG,Normando D

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To explore the pathophysiology of proliferative verrucous leukoplakia, a rare oral disorder that exhibits high rates of recurrence and malignant transformation, through a RNAseq case-control study. MATERIAL AND METHODS:We obtained oral biopsies from 10 patients with verrucous leukoplakia lesions and from th...

journal_title：Clinical oral investigations

authors： Llorens C,Soriano B,Trilla-Fuertes L,Bagan L,Ramos-Ruiz R,Gamez-Pozo A,Peña C,Bagan JV

更新日期：2020-09-11 00:00:00