abstract：INTRODUCTION:Gait speed (GS) is a predictor of negative outcomes in older adults and in those in risk to develop cognitive impairment; as such, it has been associated with dementia. Studies in Latin-American older adults showing this association are scarce. This study aimed to evaluate the relationship between GS and d...

journal_title：Dementia and geriatric cognitive disorders

authors： Garcia-Cifuentes E,Márquez I,Vasquez D,Aguillon D,Borda MG,Lopera F,Cano-Gutierrez C

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms (NPS) in dementia have received much attention due to their high prevalence and their significant implications. NPS in mild cognitive impairment (MCI), a clinical concept proposed as an intermediate state between normal aging and dementia, is now gradually gaining in interest. We ai...

journal_title：Dementia and geriatric cognitive disorders

authors： Martin E,Velayudhan L

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:The logopenic variant of primary progressive aphasia (lvPPA) is characterized by impaired word-finding and sentence repetition with phonologic errors but spared motor speech and grammar and semantic knowledge. Although its language deficits have been well studied, the full spectrum of cognitive changes ...

journal_title：Dementia and geriatric cognitive disorders

authors： Montreuil S,Poulin E,Bergeron D,Sellami L,Verret L,Fortin MP,Poulin S,Macoir J,Hudon C,Bouchard RW,Lavoie M,Laforce R

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIM:The prevalence of cognitive symptoms in recently diagnosed Parkinson's disease (PD) patients may be as high as 60%. We report a novel deep brain stimulation (DBS) strategy targeting both motor and cognitive symptoms. METHODS:A PD patient diagnosed with mild cognitive impairment underwent DBS surgery tar...

journal_title：Dementia and geriatric cognitive disorders

authors： Nombela C,Lozano A,Villanueva C,Barcia JA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The capacity to mitigate dementia symptomology despite the prevailing brain pathology has been attributed to cognitive reserve. OBJECTIVES:This study aimed to investigate how psychometric performance differs between individuals with a high school versus college education (surrogate measures for medium and h...

journal_title：Dementia and geriatric cognitive disorders

authors： Rodriguez FS,Zheng L,Chui HC,Aging Brain: Vasculature, Ischemia, and Behavior Study.

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Different studies have proven the effectiveness of cognitive stimulation (CS) for people with mild to moderate dementia, but further research is needed to gain insight into how CS interventions should be designed and developed. OBJECTIVES:The objective of this study was to gather and analyze data about th...

journal_title：Dementia and geriatric cognitive disorders

authors： Tato-Colín S,Hurtado-Aznar LA,García-Rodríguez I,Benavides-Cuéllar C,Sánchez-Valdeón L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:A large proportion of patients at memory disorders clinics are classified as having subjective cognitive impairment (SCI). Previous research has investigated whether particular lifestyle factors known to affect cognition can be useful in differentiating patients who do not show objective evidence of mem...

journal_title：Dementia and geriatric cognitive disorders

authors： Andersson C,Marklund K,Walles H,Hagman G,Miley-Akerstedt A

更新日期：2019-01-01 00:00:00

abstract：AIMS:Limited research has been done on the functional connectivity in visuoperceptual regions in dementia with Lewy bodies (DLB) patients. This study aimed to investigate the functional connectivity differences between a task condition and an inter-task resting state condition within a visuoperceptual paradigm, in DLB ...

journal_title：Dementia and geriatric cognitive disorders

authors： Chabran E,Roquet D,Gounot D,Sourty M,Armspach JP,Blanc F

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:We investigated the relationship between sleep disturbance and cognitive decline or clinical conversion in individuals with normal cognition (CN), as well as those with mild cognitive impairment (MCI) and dementia due to Alzheimer disease (AD-dementia). METHODS:Secondary analysis of 1,629 adults between 48 ...

journal_title：Dementia and geriatric cognitive disorders

authors： Mecca AP,Michalak HR,McDonald JW,Kemp EC,Pugh EA,Becker ML,Mecca MC,van Dyck CH,The Alzheimer’s Disease Neuroimaging Initiative (ADNI).

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Low muscle strength and muscle mass are associated with adverse outcomes in older hospitalized patients. The aim of this study was to assess the association between cognitive functioning and muscle strength and muscle mass in hospitalized older patients. METHODS:This prospective inception cohort included 37...

journal_title：Dementia and geriatric cognitive disorders

authors： van Dam R,Van Ancum JM,Verlaan S,Scheerman K,Meskers CGM,Maier AB

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Dementia cafés are becoming widespread as a new approach to dementia care, but their operational procedures and significance have not been adequately studied. METHODS:On-the-job training (OJT) for professionals planning to operate a dementia café in the future was conducted in a pioneering dementia caf...

journal_title：Dementia and geriatric cognitive disorders

authors： Takechi H,Sugihara Y,Matsumoto H,Yamada H

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Older people undergoing surgery are at risk of developing postoperative cognitive dysfunction (POCD), but little is known of risk factors predisposing patients to POCD. Our objective was to estimate the risk of POCD associated with exposure to preoperative diabetes, hypertension, and obesity. METHODS:O...

journal_title：Dementia and geriatric cognitive disorders

authors： Lachmann G,Feinkohl I,Borchers F,Ottens TH,Nathoe HM,Sauer AM,Dieleman JM,Radtke FM,van Dijk D,Spies C,Pischon T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Bright light treatment is a therapeutic intervention mainly used to treat sleep and circadian disturbances in Alzheimer's disease (AD) patients. Recently, a handful of studies also focused on the effect on cognition and behavior. Conflicting findings are reported in the literature, and no definite conclusion...

journal_title：Dementia and geriatric cognitive disorders

authors： Mitolo M,Tonon C,La Morgia C,Testa C,Carelli V,Lodi R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Most studies examining episodic memory in Alzheimer disease (AD) have focused on patients' impaired ability to remember information. This approach provides only a partial picture of memory deficits since other factors involved are not considered. OBJECTIVE:To evaluate the recognition memory performance by u...

journal_title：Dementia and geriatric cognitive disorders

authors： Russo MJ,Cohen G,Campos J,Martin ME,Clarens MF,Sabe L,Barcelo E,Allegri RF

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Several biomarkers have been proposed to discriminate sporadic Creutzfeldt-Jakob disease (sCJD) from other dementias and control cases. However, their clinical accuracy depends on the PRNP codon 129 genotype, leaving it unclear how well established markers behave in untested conditions. METHODS:We analyzed ...

journal_title：Dementia and geriatric cognitive disorders

authors： Llorens F,Karch A,Golanska E,Schmitz M,Lange P,Sikorska B,Liberski PP,Zerr I

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Our aim was to evaluate and compare the diagnostic properties of 5 screening tests for the diagnosis of mild Alzheimer disease (AD). METHODS:We conducted a prospective and cross-sectional study of 92 patients with mild AD and of 68 healthy controls from our Department of Neurology. The diagnostic properties...

journal_title：Dementia and geriatric cognitive disorders

authors： Matías-Guiu JA,Valles-Salgado M,Rognoni T,Hamre-Gil F,Moreno-Ramos T,Matías-Guiu J

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although some patients with primary progressive aphasia (PPA) exhibit novel or improved skills after the onset of dementia, these changes have yet to be quantified. Therefore, this study systematically explored and identified the emergence of positive behaviours after dementia onset. METHODS:This study...

journal_title：Dementia and geriatric cognitive disorders

authors： Midorikawa A,Kumfor F,Leyton CE,Foxe D,Landin-Romero R,Hodges JR,Piguet O

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:We identified and studied 13 patients carrying the P301L mutation in the MAPT gene from the same area (Baix Llobregat County) in Barcelona, Spain. METHODS:The demographic and clinical features were reviewed retrospectively. Detailed neuropathological characterization was obtained in 9 subjects. To inve...

journal_title：Dementia and geriatric cognitive disorders

authors： Borrego-Écija S,Morgado J,Palencia-Madrid L,Grau-Rivera O,Reñé R,Hernández I,Almenar C,Balasa M,Antonell A,Molinuevo JL,Lladó A,Martínez de Pancorbo M,Gelpi E,Sánchez-Valle R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:White matter injury is an important factor for cognitive impairment in memory clinic patients. We determined the added value of diffusion tensor imaging (DTI) of strategic white matter tracts in explaining variance in cognition in memory clinic patients with vascular brain injury. METHODS:We included 159 pa...

journal_title：Dementia and geriatric cognitive disorders

authors： Biesbroek JM,Leemans A,den Bakker H,Duering M,Gesierich B,Koek HL,van den Berg E,Postma A,Biessels GJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The apolipoprotein E (APOE) e4 genetic polymorphism is a major risk factor for Alzheimer' s disease, hence the possible prevention of its detrimental effects on cognition is of high relevance. METHODS:We used linear regression models to assess associations of APOE e4 with cognitive performance in a populati...

journal_title：Dementia and geriatric cognitive disorders

authors： Perna L,Mons U,Rujescu D,Kliegel M,Brenner H

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Prior studies have shown that patients with dementia are at risk of receiving insufficient treatment for pain after a hip fracture. We therefore hypothesized that elderly hip fracture patients with dementia received less postoperative pain treatment than those without dementia. METHOD:All patients (age...

journal_title：Dementia and geriatric cognitive disorders

authors： Jensen-Dahm C,Palm H,Gasse C,Dahl JB,Waldemar G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:The prevalence of mild cognitive impairment (MCI) and its subtypes among Chinese older adults, and the contribution of vascular risk factors (VRF) and vascular disorders to MCI remain unclear. This study aims to investigate the prevalence of MCI and its different subtypes, and clarify the role of VRF an...

journal_title：Dementia and geriatric cognitive disorders

authors： Ma F,Wu T,Zhao J,Ji L,Song A,Zhang M,Huang G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Depressive symptoms are commonly observed in Alzheimer's disease (AD). The underlying mechanisms of depressive symptoms in AD remain unclear; frontolimbic circuitry dysfunction may play a role. We aimed to investigate the microstructural integrity of frontolimbic connectivity of specific fiber tracts in...

journal_title：Dementia and geriatric cognitive disorders

authors： Zhu Q,Lin M,Bi S,Ni Z,Zhao J,Chen B,Fan G,Shang X

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The Clinical Dementia Rating Scale (CDR) is used to rate dementia severity. Its utility in diagnosing mild cognitive impairment (MCI) and its predictive value remain unknown. AIMS:The aim of this study was to examine the association between CDR scores and expert MCI diagnosis, and to determine whether basel...

journal_title：Dementia and geriatric cognitive disorders

authors： Woolf C,Slavin MJ,Draper B,Thomassen F,Kochan NA,Reppermund S,Crawford JD,Trollor JN,Brodaty H,Sachdev PS

更新日期：2016-01-01 00:00:00

abstract：AIMS:To describe the contribution of white matter lesions to the long-term neuropsychological profiles of different groups of clinical diagnoses, and to identify neuropsychological predictors of cognitive impairment in a 10-year follow-up. METHODS:The Lisbon subcohort of the Leukoaraiosis and Disability (LADIS) study ...

journal_title：Dementia and geriatric cognitive disorders

authors： Madureira S,Verdelho A,Moleiro C,Santos C,Scheltens P,Gouw A,Ferro J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Midlife hypertension followed by late life hypotension resulting from neurodegeneration increases amyloidogenesis and tauopathy. METHODS:Consecutive outpatients with late-onset Alzheimer's disease (AD) at various stages and their respective caregivers were assessed for score variations in 1 year of tests as...

journal_title：Dementia and geriatric cognitive disorders

authors： de Oliveira FF,Chen ES,Smith MC,Bertolucci PH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to elucidate the relationship between Alzheimer's disease (AD) and the serotonin transporter gene (SLC6A4). METHODS:AD subjects (n = 43) and controls (n = 47) were recruited and evaluated. In leukocytes, we evaluated two polymorphisms in SLC6A4, the serotonin transporter length...

journal_title：Dementia and geriatric cognitive disorders

authors： Yamazaki K,Yoshino Y,Mori T,Okita M,Yoshida T,Mori Y,Ozaki Y,Sao T,Iga J,Ueno S

更新日期：2016-01-01 00:00:00

abstract：AIMS:The objective of this study was to investigate the relation between impaired fine motor skills in Parkinson disease (PD) patients and their cognitive status, and to determine whether fine motor skills are more impaired in PD patients with mild cognitive impairment (MCI) than in non-MCI patients. METHODS:Twenty PD...

journal_title：Dementia and geriatric cognitive disorders

authors： Dahdal P,Meyer A,Chaturvedi M,Nowak K,Roesch AD,Fuhr P,Gschwandtner U

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Omega-3 polyunsaturated fatty acids (PUFA) may affect the risk of cognitive decline in older adults. METHODS:Cross-sectional analysis was conducted among 720 (50.4% women) participants aged 68-92 years (mean age: 77.6, SD ±6.2) of the population-based KORA-Age study. Eicosapentaenoic acid and docosahexaenoi...

journal_title：Dementia and geriatric cognitive disorders

authors： Lukaschek K,von Schacky C,Kruse J,Ladwig KH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) and frontotemporal dementia (FTD) are two common forms of primary neurodegenerative dementia. Mutations in 3 genes (PSEN1, PSEN2, and APP) have been identified in patients with early-onset AD. METHODS:We performed gene sequencing in PSEN1, PSEN2, and APP in 61 AD and 35 FTD Chinese ...

journal_title：Dementia and geriatric cognitive disorders

authors： Shi Z,Wang Y,Liu S,Liu M,Liu S,Zhou Y,Wang J,Cai L,Huo YR,Gao S,Ji Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:We investigated the histopathological correlates of white matter hyperintensities (WMHs) in participants with Alzheimer's disease (AD) or cerebrovascular disease, and in aged controls. METHODS:We reviewed 57 participants who had neuropathology and in whom neuroimaging was done. In addition to AD pathol...

journal_title：Dementia and geriatric cognitive disorders

authors： Shim YS,Yang DW,Roe CM,Coats MA,Benzinger TL,Xiong C,Galvin JE,Cairns NJ,Morris JC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The diagnosis of delirium is not supported by specific biomarkers. In a previous study, high neopterin levels were found in patients with a postoperative delirium. In the present study, we investigated levels of neopterin, interleukin-6 (IL-6) and insulin-like growth factor-1 (IGF-1) in acutely ill admi...

journal_title：Dementia and geriatric cognitive disorders

authors： Egberts A,Wijnbeld EH,Fekkes D,van der Ploeg MA,Ziere G,Hooijkaas H,van der Cammen TJ,Mattace-Raso FU

更新日期：2015-01-01 00:00:00

abstract：AIM:To conduct a prospective analysis of the neuropsychiatric symptoms (NPS) across the three categories of primary progressive aphasia (PPA) and progressive apraxia of speech (PAOS), compare the prevalence and nature of the symptoms, and look at which symptoms could be helpful to better differentiate these PPA and PAO...

journal_title：Dementia and geriatric cognitive disorders

authors： Singh TD,Duffy JR,Strand EA,Machulda MM,Whitwell JL,Josephs KA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of the present study was to provide normative data and determine the validity of the Czech version of the Mattis Dementia Rating Scale 2 (czDRS-2) in screening for mild cognitive impairment in Parkinson's disease (PD-MCI) based on the Movement Disorder Society (MDS) Level II criteria. METHODS:F...

journal_title：Dementia and geriatric cognitive disorders

authors： Bezdicek O,Michalec J,Nikolai T,Havránková P,Roth J,Jech R,Růžička E

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To examine the influence of cognitive impairment on the functional outcomes and complication rates of patients with hip fracture during in-patient treatment. METHODS:A total of 402 patients who were surgically treated for hip fractures were consecutively enrolled at a single trauma center. The patients were ...

journal_title：Dementia and geriatric cognitive disorders

authors： Bliemel C,Lechler P,Oberkircher L,Colcuc C,Balzer-Geldsetzer M,Dodel R,Ruchholtz S,Buecking B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Existing cognitive measures for moderate-to-severe dementia have shown floor effects and an inability to assess the remaining cognitive function, especially for profound dementia. METHODS:We constructed the Cognitive Test for Severe Dementia (CTSD), which consists of 13 items covering 7 cognitive domai...

journal_title：Dementia and geriatric cognitive disorders

authors： Tanaka H,Nagata Y,Uematsu M,Takebayashi T,Hanada K,Inokawa M,Fukuhara K,Ogawa Y,Haga D,Kakegawa Y,Nishikawa T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Estimations of life expectancies (LE) in health and ill health are important for planning future health care support. This study aimed at quantifying whether an increased LE is accompanied by an increase in the duration of life with dementia (DemLE) in Hong Kong SAR. METHODS:Two parameters from a logistic m...

journal_title：Dementia and geriatric cognitive disorders

authors： Cheung SL,Yip SF,Branch LG,Robine JM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aims of this study were to determine baseline factors related to the progression of subjective memory impairment (SMI) in elderly subjects and to develop a new modeling scale to predict progression. METHODS:Elderly subjects with SMI were recruited from the nationwide Clinical Research Centers for D...

journal_title：Dementia and geriatric cognitive disorders

authors： Hong YJ,Yoon B,Shim YS,Kim SO,Kim HJ,Choi SH,Jeong JH,Yoon SJ,Yang DW,Lee JH

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to investigate whether the serial position effects in memory can differentiate patients with different subtypes of mild cognitive impairment (MCI) from healthy controls and patients with different stages of Alzheimer's disease (AD). METHODS:The serial position effects was tested with t...

journal_title：Dementia and geriatric cognitive disorders

authors： Moser B,Deisenhammer EA,Marksteiner J,Papousek I,Fink A,Weiss EM

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the cognitive performance of institutionalized elderly in the city of Natal, state of Rio Grande do Norte, Brazil. METHODS:A descriptive, longitudinal study of 85 aged individuals via an interview conducted following the application of a classification form and the Mini-Mental State Examination (...

journal_title：Dementia and geriatric cognitive disorders

authors： Medeiros de A Nunes V,Alchieri JC,Azevedo LM,Varela de Oliveira KM,Pereira DA

更新日期：2014-01-01 00:00:00