解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:AIMS:To evaluate the patients' perceptions of telemedicine visits during COVID-19 lockdown and their level of anxiety about COVID and diabetic foot (DF). METHODS:In May 2020, we contacted by phone all the patients who underwent in March and April to remote monitoring visits for DF during the lockdown for COVID-19, wit...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01653-y
更新日期:2021-01-13 00:00:00
abstract:AIMS:Medication adherence and persistence are important determinants of treatment success in type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis evaluated the real-world adherence, persistence, and in-class switching among patients with T2DM prescribed dipeptidyl peptidase-4 (DPP4) inhibitors. ME...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01590-w
更新日期:2021-01-01 00:00:00
abstract:AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01552-2
更新日期:2020-12-01 00:00:00
abstract:AIMS:To evaluate the efficacy and safety of intravitreal dexamethasone implant (DEX-implant) for diabetic macular edema (DME) in real-life practice with an extended follow-up for up to 5 year. METHODS:This multicentric retrospective study reviewed 227 eyes of 152 patients with DME treated by DEX-implant. Main outcome ...
journal_title:Acta diabetologica
pub_type: 杂志文章,多中心研究
doi:10.1007/s00592-020-01561-1
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Psychosocial factors like diabetes distress and social support, as well as the presence of complications, affect an individual's self-management ability; however, their role in adherence behaviours is not yet clear. We examined the role of psychosocial factors and complications in non-adherence behaviours in...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01609-2
更新日期:2020-11-19 00:00:00
abstract:AIM:The study evaluated the effect of different concentrations of sildenafil-containing ointment on wound healing in healthy and streptozotocin (STZ)-induced diabetic rats. METHODS:A total of 108 Sprague Dawley male rats aged 5 months were randomly divided into two groups: healthy and diabetes-inducing rats. Following...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01562-0
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Circulating levels of TNF alpha receptor 1 (TNFR1) and 2 (TNFR2) are associated with increased long-term mortality and impaired kidney function. AIM:To study association between circulating levels of TNFR1 and TNFR2 and short-term mortality in patients with diabetes and dyspnea. POPULATION AND METHODS:Pati...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01527-3
更新日期:2020-10-01 00:00:00
abstract:AIM:Infection of a diabetic foot ulcer (DFU) is common. More than the half of DFUs become infected and 15-20% of them necessitate amputation in course of treatment. Diabetic foot infection (DFI) is therefore the major cause for non-traumatic lower limb amputation in Germany. Prompt and effective treatment of DFI is man...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01587-5
更新日期:2020-09-17 00:00:00
abstract::Diabetes cardiomyopathy is a specific form of cardiac disease characteristic for diabetic patients. Development of echocardiography enabled diagnosis of diabetic cardiomyopathy significantly before the occurrence of heart failure. Previously was believed that left ventricular (LV) diastolic dysfunction represents the ...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-020-01528-2
更新日期:2020-09-01 00:00:00
abstract:AIMS:The aim of the current study was to investigate the association of type 2 diabetes (T2D) and insulin treatment with changes in muscle mass, muscle strength, and physical performance in older adults. METHODS:In 731 participants of the population-based KORA-Age study aged 74.6 ± 6.2 years (T2D: n = 118; insulin tre...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01523-7
更新日期:2020-09-01 00:00:00
abstract:AIMS:To investigate whether intravitreal conbercept injection affects contralateral untreated eyes in bilateral diabetic macular edema (DME) patients. METHODS:In this retrospective study, 15 patients (30 eyes) with type 2 diabetes were followed after bilateral DME diagnosis in the Department of Ophthalmology, Peking U...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01511-x
更新日期:2020-08-01 00:00:00
abstract:AIMS:Hyperreflective foci (HF), detected in the retina of diabetic patients, suggest the presence of microglial activation and migration, while controversies still remain for the origin of HF to be precursors of hard exudates. We investigated the presence of HF and their association with dyslipidemia in serous retinal ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01495-8
更新日期:2020-07-01 00:00:00
abstract::Left atrial (LA) structural, functional and mechanical changes have important role in development of diabetic cardiomyopathy and it was discovered that LA remodeling has important prognostic role in the patients with diabetes (DM). Previously the focus of echocardiographic studies in DM population was on the left vent...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-020-01557-x
更新日期:2020-06-09 00:00:00
abstract:AIMS:Observational studies and meta-analyses of randomized trials on dipeptidyl peptidase-4 inhibitors (DPP4i) reported discordant results on the risk of malignancies with this class of drugs. Aim of the present meta-analysis is the assessment of the effect of DPP4i treatment on the incidence of different types of canc...
journal_title:Acta diabetologica
pub_type: 杂志文章,meta分析
doi:10.1007/s00592-020-01479-8
更新日期:2020-06-01 00:00:00
abstract:AIMS:Glucagon is used to resolve severe hypoglycemia in unconscious patients with diabetes, requiring third-party assistance. A few studies have shown that intranasal (IN) glucagon causes resolution of hypoglycemia in insulin-treated patients with type 1 (T1DM) diabetes. This systematic review and meta-analysis updates...
journal_title:Acta diabetologica
pub_type: 杂志文章,meta分析
doi:10.1007/s00592-020-01483-y
更新日期:2020-06-01 00:00:00
abstract:AIMS:Glucose-dependent insulinotropic polypeptide (GIP) is released primarily from the proximal small intestine and glucagon-like peptide-1 (GLP-1) from the more distal small intestine and colon. Their relative importance to the incretin effect in health has been contentious in the past, although it now appears that GI...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01461-z
更新日期:2020-05-01 00:00:00
abstract:AIMS:Familial partial lipodystrophy (FPLD) is a rare autosomal dominant disorder, mostly due to mutations in lamin A (LMNA) or in peroxisome proliferator-activated receptor gamma (PPARG) genes. In the present study, we aimed to identify and functionally characterize the genetic defect underlying FPLD in an Italian fami...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01462-y
更新日期:2020-05-01 00:00:00
abstract:AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01436-0
更新日期:2020-04-01 00:00:00
abstract:AIMS:High glycemic variability (GV) is the major indication for islet transplantation (IT) in patients with type 1 diabetes (T1D). The actual criteria used to assess graft function do not consider GV improvement. Our study aimed to describe GV indices' evolution in T1D patients who benefited from IT during the TRIMECO ...
journal_title:Acta diabetologica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00592-019-01425-3
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:International comparisons of diabetes-related lower extremity amputation rates are still hampered by different criteria used for data collection and analysis. We aimed to evaluate trends and variation of major/minor amputations, using agreed definitions adopted by the Organization for Economic Cooperation an...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01423-5
更新日期:2020-03-01 00:00:00
abstract::Positron emission tomography/computed tomography (PET/CT) is a standard procedure for imaging cancer commonly used in the clinical practice for several diseases, in particular for cancer staging, restaging, treatment monitoring and radiation therapy planning. Despite the availability of many radiotracers, 18F-fluoro-2...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-019-01385-8
更新日期:2020-03-01 00:00:00
abstract:AIMS:The aim of our study was to estimate the overall rate of first hospitalizations for diabetic foot (DF) regardless of the outcome in amputations, as well as the mortality rate with their determinants in the period 2012-2016 in Piedmont Region in Italy. METHODS:The study included all the subjects registered in the ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01412-8
更新日期:2020-02-01 00:00:00
abstract:AIM:To identify the potential metabolite markers in diabetic retinopathy (DR) by using gas chromatography coupled with time-of-flight mass spectrometry (GC-TOFMS). METHODS:GC-TOFMS spectra were acquired from vitreous and aqueous humor (AH) samples of patients with DR and non-diabetic participants. Comparative analysis...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01363-0
更新日期:2020-01-01 00:00:00
abstract:AIM:To assess the association between alcohol consumption and/or cigarette smoking with other unhealthy behaviors and clinical cardiovascular risk factors in youth with type 1 diabetes. METHODS:Two hundred and twenty-eight youth with type 1 diabetes (age 13-19 years) were consecutively enrolled in three Regional Pedia...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01415-5
更新日期:2019-12-01 00:00:00
abstract:AIMS:We studied mortality in individuals of diabetes with or without Charcot neuroarthropathy (CN). METHODS:People attending diabetic foot care facility with CN of foot (Cohort 1) were prospectively evaluated. Details pertaining to the duration of diabetes, microvascular and macrovascular complications, foot ulcer, am...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-019-01376-9
更新日期:2019-12-01 00:00:00
abstract:AIMS:To investigate the possibility of identifying a subtype of latent autoimmune diabetes in adults (LADA), T-LADA (T cell responses-positive and autoantibody-negative) from patients with phenotypic type 2 diabetes (T2D) by enzyme-linked immunospot (ELISPOT). METHODS:Eighty-two patients with phenotypic T2D were studi...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01391-w
更新日期:2019-11-01 00:00:00
abstract:AIMS:In patients with type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and liver fibrosis is frequent and presumably associated with increased cardiovascular disease risk and mortality. The objective was to investigate risk factors associated with hepatic fibrosis in patients with type 2 diabetes and NAFLD to...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01374-x
更新日期:2019-11-01 00:00:00
abstract:AIMS:This study aimed to assess islet insulin secretion and insulin resistance in Chinese patients with latent autoimmune diabetes in adults (LADA). METHODS:Twelve patients with LADA, 10 with type 1 diabetes mellitus (T1DM), 10 with type 2 diabetes mellitus (T2DM), and 10 nondiabetic healthy controls (HCs) were includ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01387-6
更新日期:2019-11-01 00:00:00
abstract:AIMS:Observational studies indicated that resting heart rate (RHR) was associated with diabetes mellitus (DM) risk; however, it remains unclear whether the association between RHR and DM is causal. We aimed to examine whether there was causal association of RHR with DM risk. METHODS:A prospective study including 16,20...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01344-3
更新日期:2019-09-01 00:00:00
abstract:AIMS:Type 2 diabetes (DM2) is associated to oxidative modifications of high-density lipoproteins (HDL), which can interfere with their function. Pioglitazone has proved effective in raising HDL cholesterol (HDL-C) and lowering small dense low-density lipoprotein (LDL), but no clinical studies have examined its effect o...
journal_title:Acta diabetologica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00592-018-01278-2
更新日期:2019-05-01 00:00:00
abstract:AIMS:To evaluate the methodological quality of systematic reviews (SRs), and summarize evidence of important outcomes from dipeptidyl peptidase-4 inhibitors (DPP4-I) in treating type 2 diabetes mellitus (T2DM). METHODS:We included SRs of DPP4-I for the treatment of T2DM until January, 2018 by searching the Cochrane Li...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-018-1164-5
更新日期:2019-01-01 00:00:00
abstract:AIMS:Maternal type 2 diabetes (T2D) can result in adverse pathological outcomes to both the mother and fetus. The present study aimed to investigate the pathological effects of maternal T2D on the gene expression patterns and functions of fetal human umbilical vein endothelial cells (HUVECs), a representative of fetal ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-018-1207-y
更新日期:2019-01-01 00:00:00
abstract::Diabetes mellitus is an independent risk factor for falling, particularly in the elderly. Due to chronic hyperglycemia and hyperinsulinemia patients with diabetes mellitus may have neurological deficits as peripheral neuropathy that is a debilitating micro-vascular complication affecting the proximal and distal periph...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-018-1183-2
更新日期:2018-12-01 00:00:00
abstract:AIMS:To assess the risk of adverse neonatal outcomes in women with gestational diabetes (GDM) by identifying subgroups of women at higher risk to recognize the characteristics most associated with an excess of risk. METHODS:Observational, retrospective, multicenter study involving consecutive women with GDM. To identi...
journal_title:Acta diabetologica
pub_type: 杂志文章,多中心研究
doi:10.1007/s00592-018-1208-x
更新日期:2018-12-01 00:00:00
abstract:AIMS:Many authors do not recommend hypoglycemic treatment during pregnancy in women affected by monogenic diabetes due to heterozygous glucokinase (GCK) mutations (MODY 2) in case of affected fetus, because maternal hyperglycemia would be necessary to achieve a normal birthweight. We aimed to evaluate differences in bi...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-018-1198-8
更新日期:2018-12-01 00:00:00
abstract:AIMS:Type 1 diabetes is increasing in children leading more T1D young adults to adult healthcare settings. This change is experienced as a tear and results in a disengagement from specialist services. This study reports on an implementation of an effective and pioneering program of transition in North Africa. METHODS:...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-018-1196-x
更新日期:2018-11-01 00:00:00
abstract::It usually takes several years (in some cases, decades) for predisposed individuals to move from the onset of type 1 or type 2 diabetes to the development of microalbuminuria, the first sign of diabetic nephropathy. This long, complication-free, period represents the best possible moment to start a successful preventi...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-018-1211-2
更新日期:2018-11-01 00:00:00
abstract::Diabetic kidney disease (DKD) is a devastating complication of Type 1 and Type 2 diabetes and leads to increased morbidity and mortality. Earlier work in families has provided strong evidence that heredity is a major determinant of DKD. Previous linkage analyses and candidate gene studies have identified potential DKD...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-018-1193-0
更新日期:2018-11-01 00:00:00
abstract::The title "Plasma fatty acid-binding protein 4 (FABP4) as a novel biomarker to predict gestational diabetes mellitus" should be replaced by "Serum fatty acid-binding protein 4 (FABP4) as a novel biomarker to predict gestational diabetes mellitus". ...
journal_title:Acta diabetologica
pub_type: 已发布勘误
doi:10.1007/s00592-018-1177-0
更新日期:2018-10-01 00:00:00
abstract:AIM:Cardio-metabolic disease and physical activity are closely related but large-scale objective studies which measure physical activity are lacking. Using the largest accelerometer cohort to date, we aimed to investigate whether there is an association between disease status and accelerometer variables after a 5-year ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-018-1161-8
更新日期:2018-09-01 00:00:00