听力与言语-语言病理学

行为科学

医学伦理学

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  • Gastropods as intermediate hosts of Angiostrongylus spp. in the Americas: bioecological characteristics and geographical distribution.

    abstract:BACKGROUND:Intermediate hosts are key organisms in maintaining parasite life cycles, because they can act as amplifiers in the transmission from natural reservoirs to humans. One of the most important groups of intermediate hosts for zoonotic nematode infections are gastropods,slugs and snails. These are essential orga...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章,评审

    doi:10.1590/0074-02760200236

    authors: Valente R,Robles MDR,Diaz JI

    更新日期:2020-11-27 00:00:00

  • Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science.

    abstract::Scientists have increasingly recognised that low methodological and analytical rigour combined with publish-or-perish incentives can make the published scientific literature unreliable. As a response to this, large-scale systematic replications of the literature have emerged as a way to assess the problem empirically....

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200328

    authors: Neves K,Carneiro CF,Wasilewska-Sampaio AP,Abreu M,Valério-Gomes B,Tan PB,Amaral OB

    更新日期:2020-10-23 00:00:00

  • COVID-19: molecular targets, drug repurposing and new avenues for drug discovery.

    abstract::Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of ongoing drug repurposing efforts for COVID-19 as well as discussing ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200254

    authors: Senger MR,Evangelista TCS,Dantas RF,Santana MVDS,Gonçalves LCS,de Souza Neto LR,Ferreira SB,Silva-Junior FP

    更新日期:2020-10-02 00:00:00

  • Molecular and serological characterization of occult hepatitis B among blood donors in Maputo, Mozambique.

    abstract:BACKGROUND:Occult hepatitis B virus (HBV) - characterized by the absence of detectable HBsAg in the presence of HBV DNA - represents a potential threat for blood safety. OBJECTIVES:This study was conducted with the aim to investigate the serological and molecular characterization of occult HBV infection (OBI) among bl...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200006

    authors: Mabunda N,Zicai AF,Ismael N,Vubil A,Mello F,Blackard JT,Lago B,Duarte V,Moraes M,Lewis L,Jani I

    更新日期:2020-09-23 00:00:00

  • Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis.

    abstract::Angiostrongylus costaricensis is the causative agent of abdominal angiostrongyliasis, a zoonotic infection that may produce severe eosinophilic enterocolitis or hepatitis in humans. Parasites are usually not released in stools and serology has an important role in diagnosis. Since cross-reactivity is demonstrated betw...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200201

    authors: Graeff-Teixeira C,Pascoal VF,Rodriguez R,Morassutti AL,Intapan PM,Maleewong W

    更新日期:2020-09-21 00:00:00

  • Increased levels of reactive oxygen species in platelets and platelet-derived microparticles and the risk of respiratory failure in HIV/AIDS patients.

    abstract::Respiratory failure (RF) is the main cause of hospital admission in HIV/AIDS patients. This study assessed comorbidities and laboratory parameters in HIV/AIDS inpatients with RF (N = 58) in relation to those without RF (N = 36). Tuberculosis showed a huge relative risk and platelet counts were slightly higher in HIV/A...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200082

    authors: Gama WM,Oliveira LB,Chaves YO,Ribeiro F,Almeida TVR,Baptista BJA,Santana MF,Ferreira LC,Lacerda MVG,Nogueira PA

    更新日期:2020-09-14 00:00:00

  • Deep sequencing of small RNAs reveals the repertoire of miRNAs and piRNAs in Biomphalaria glabrata.

    abstract:BACKGROUND:Biomphalaria glabrata snails are widely distributed in schistosomiasis endemic areas like America and Caribe, displaying high susceptibility to infection by Schistosoma mansoni. After the availability of B. glabrata genome and transcriptome data, studies focusing on genetic markers and small non-coding RNAs ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190498

    authors: Queiroz FR,Portilho LG,Jeremias WJ,Babá ÉH,do Amaral LR,Silva LM,Coelho PMZ,Caldeira RL,Gomes MS

    更新日期:2020-07-01 00:00:00

  • FLI1 gene influences lesion size and skin test may predict therapeutic response in cutaneous leishmaniasis.

    abstract::Genes associated with wound healing have been shown to be risk factors for cutaneous leishmaniasis (CL) which is caused by Leishmania braziliensis. In this study, we examined whether the genes previously associated with CL influenced the clinical outcome. Patients were genotyped and retrospectively classified as respo...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190361

    authors: da Hora AS,de Almeida LF,do Lago TS,Machado PR,Castellucci LC

    更新日期:2020-03-02 00:00:00

  • Application of WHO International Biological Reference Standards to evaluate commercial serological tests for chronic Chagas disease.

    abstract::BACKGROUND Chagas disease, resulting from Trypanosoma cruzi infections, continues to be a health concern mainly in Latin American countries where the parasite is endemic. The laboratory diagnosis of a chronic infection is determined through serological assays for antibodies against T. cruzi and several tests are avail...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200214

    authors: Sáez-Alquezar A,Junqueira ACV,Durans ADM,Guimarães AV,Corrêa JA,Provance DW Jr,Cabello PH,Coura JR,Viñas PA

    更新日期:2020-01-01 00:00:00

  • Fungal-host interactions: insights into microRNA in response to Paracoccidioides species.

    abstract::BACKGROUND Paracoccidioides spp. causes paracoccidioidomycosis (PCM), an important and frequent systemic mycosis that occurs in Latin America. The infectious process begins with contact between the fungus and lung cells, and the molecular pattern of this interaction is currently poorly understood. MicroRNAs (miRNAs) a...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200238

    authors: Singulani JL,Silva JFD,Gullo FP,Costa MC,Fusco-Almeida AM,Enguita FJ,Mendes-Giannini MJS

    更新日期:2020-01-01 00:00:00

  • The influence of meteorological variables on the oviposition dynamics of Aedes aegypti (Diptera: Culicidae) in four environmentally distinct areas in northeast Brazil.

    abstract::BACKGROUND Fluctuations in climate have been associated with variations in mosquito abundance. OBJECTIVES To analyse the influence of precipitation, temperature, solar radiation, wind speed and humidity on the oviposition dynamics of Aedes aegypti in three distinct environmental areas (Brasília Teimosa, Morro da Conce...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760200046

    authors: Santos ICDS,Braga C,de Souza WV,de Oliveira ALS,Regis LN

    更新日期:2020-01-01 00:00:00

  • Increasing the digital repository of DNA barcoding sequences of sand flies (Psychodidae: Phlebotominae).

    abstract::Sand fly identification is complex because it depends on the expertise of the taxonomist. The females show subtle morphological differences and the occurrence of the species complexes are usual in this taxon. Therefore, a fragment of the cytochrome c oxidase subunit I (COI) gene is used for taxon barcoding to resolve ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190208

    authors: Laurito M,Ontivero IM,Almirón WR

    更新日期:2019-11-28 00:00:00

  • Liaisons dangereuses: cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito Aedes aegypti from Brazil and French Guiana.

    abstract:BACKGROUND:In recent years, South America has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and Zika. Aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. OBJECTIVES:In order to improve vector control it is essentia...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190120

    authors: Salgueiro P,Restrepo-Zabaleta J,Costa M,Galardo AKR,Pinto J,Gaborit P,Guidez A,Martins AJ,Dusfour I

    更新日期:2019-09-23 00:00:00

  • First isolation of West Nile virus in Brazil.

    abstract:BACKGROUND:Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from equine and human hosts but the virus had never been isolated in the country. OBJECTIVES:We sought to identify the viral etiology of equine encephalitis in Espírito Santo state. METHODS:We performed...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180332

    authors: Martins LC,Silva EVPD,Casseb LMN,Silva SPD,Cruz ACR,Pantoja JAS,Medeiros DBA,Martins Filho AJ,Cruz EDRMD,Araújo MTF,Cardoso JF,Cunha MACRD,Almada GL,Romano APM,Santos MGDP,Rodrigues GAP,Chiang JO,Quaresma JAS,Carvalho

    更新日期:2019-01-17 00:00:00

  • Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni.

    abstract::The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190029

    authors: Fidelis TAA,Brasileiro-Filho G,Santos HH,Vasconcelos-Santos DV,Parreiras PM,Coelho PMZ,Araujo N,Chaud MV,Lambertucci JR

    更新日期:2019-01-01 00:00:00

  • Previous dengue or Zika virus exposure can drive to infection enhancement or neutralisation of other flaviviruses.

    abstract:BACKGROUND:Dengue virus (DENV) has circulated in Brazil for over 30 years. During this time, one serotype has cyclically replaced the other, until recently, when all four distinct serotypes began to circulate together. Persistent circulation of DENV for long time periods makes sequential infections throughout a person'...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190098

    authors: Oliveira RA,de Oliveira-Filho EF,Fernandes AI,Brito CA,Marques ET,Tenório MC,Gil LH

    更新日期:2019-01-01 00:00:00

  • Combination of surveillance tools reveals that Yellow Fever virus can remain in the same Atlantic Forest area at least for three transmission seasons.

    abstract:BACKGROUND:In Brazil, the Yellow Fever virus (YFV) is endemic in the Amazon, from where it eventually expands into epidemic waves. Coastal south-eastern (SE) Brazil, which has been a YFV-free region for eight decades, has reported a severe sylvatic outbreak since 2016. The virus spread from the north toward the south o...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190076

    authors: Abreu FVS,Delatorre E,Dos Santos AAC,Ferreira-de-Brito A,de Castro MG,Ribeiro IP,Furtado ND,Vargas WP,Ribeiro MS,Meneguete P,Bonaldo MC,Bello G,Lourenço-de-Oliveira R

    更新日期:2019-01-01 00:00:00

  • Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil.

    abstract:BACKGROUND:Dengue is an arthropod-borne viral disease with a majority of asymptomatic individuals and clinical manifestations varying from mild fever to severe and potentially lethal forms. An increasing number of genetic studies have outlined the association between host genetic variations and dengue severity. Genes a...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190004

    authors: Ornelas AMM,Xavier-de-Carvalho C,Alvarado-Arnez LE,Ribeiro-Alves M,Rossi ÁD,Tanuri A,de Aguiar RS,Moraes MO,Cardoso CC

    更新日期:2019-01-01 00:00:00

  • Neutrophil CD64 expression levels in IGRA-positive individuals distinguish latent tuberculosis from active disease.

    abstract:BACKGROUND:CD64 (FcγR1) is a high-affinity receptor for monomeric IgG1 and IgG3. Circulating neutrophils express very low amounts of CD64 on their surface. OBJECTIVES:Our primary aim was to investigate the utility of neutrophil CD64 surface expression as a biomarker of active pulmonary tuberculosis (TB). We hypothesis...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180579

    authors: Corrêa RDS,Rodrigues LS,Pereira LHL,Nogueira OC,Leung J,Sousa MDS,Hacker MA,Siqueira HR,Capone D,Alves RLR,Pessolani MCV,Schmitz V,Pereira GMB

    更新日期:2019-01-01 00:00:00

  • Evolutionary study of potentially zoonotic hepatitis E virus genotype 3 from swine in Northeast Brazil.

    abstract::Hepatitis E virus (HEV), an emerging virus associated with acute hepatic disease, leads to thousands of deaths worldwide. HEV has already been reported in Brazil; however, there is a lack of epidemiological and molecular information on the genetic variability, taxonomy, and evolution of HEV. It is thus unclear whether...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180585

    authors: Oliveira-Filho EF,Dos Santos DR,Durães-Carvalho R,da Silva A,de Lima GB,Batista Filho AFB,Pena LJ,Gil LH

    更新日期:2019-01-01 00:00:00

  • Criteria for identification of Schistosoma mansoni eggs in faecal sediments prepared with the Helmintex method and stained by ninhydrin.

    abstract::Helmintex is a sensitive method used for detecting Schistosoma mansoni eggs. Here, we describe the observed frequency of six proposed criteria associated with the identification of S. mansoni eggs prepared with the Helmintex method and stained with ninhydrin. The efficacy of these criteria in classifying S. mansoni eg...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180529

    authors: de Souza RP,Favero V,Pascoal VF,Lindholz C,Bittencourt HR,Graeff-Teixeira C

    更新日期:2019-01-01 00:00:00

  • Molecular epidemiology of Hepatitis delta virus infection in Minas Gerais state from Brazil, an area outside the hyperendemic region of the Amazon Basin.

    abstract:BACKGROUND:Hepatitis delta virus (HDV) infections in hepatitis B virus (HBV) carriers are the most severe form of viral hepatitis. HDV prevalence is high in the Brazilian Amazon, but studies in other regions of the country are still scarce and often underestimated its prevalence by including a small numbers of individu...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190074

    authors: Scarponi CF,Kroon EG,Vieira DS,Fernandes AP,Gomes KB,Mota BE

    更新日期:2019-01-01 00:00:00

  • Mycobacterium genus and tRNA arrays.

    abstract::The presence of tRNA array, a region with high tRNA gene number and density, has been demonstrated in Mycobacterium genus. However, a recent phylogenomic study revealed the existence of five distinct monophyletic groups (genera) within this genus. Considering this new scenario, and based on in-silico analyses, we have...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180443

    authors: Morgado SM,Vicente ACP

    更新日期:2019-01-01 00:00:00

  • Fibrosis: a distinguishing feature in the pathology of neural leprosy.

    abstract:BACKGROUND:Fibrosis in the peripheral nerve is the end stage of leprous neuropathy and the cause of the resulting permanent neural function impairments. Preventive measures to avoid this irreversible pathological state are a relief strategy for leprosy sufferers. OBJECTIVES:The present study describes the frequency of...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760190056

    authors: Antunes SLG,Jardim MR,Vital RT,Pascarelli BMO,Nery JADC,Amadeu TP,Sales AM,da Costa EAF,Sarno EN

    更新日期:2019-01-01 00:00:00

  • Complete and de novo assembly of the Leishmania braziliensis (M2904) genome.

    abstract::Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180438

    authors: González-de la Fuente S,Camacho E,Peiró-Pastor R,Rastrojo A,Carrasco-Ramiro F,Aguado B,Requena JM

    更新日期:2018-12-10 00:00:00

  • Commercial drugs containing flavonoids are active in mice with malaria and in vitro against chloroquine-resistant Plasmodium falciparum.

    abstract::BACKGROUND The main strategy to control human malaria still relies on specific drug treatment, limited now by Plasmodium falciparum-resistant parasites, including that against artemisinin derivatives. Despite the large number of active compounds described in the literature, few of them reached full development against...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180279

    authors: Penna-Coutinho J,Aguiar AC,Krettli\/ AU

    更新日期:2018-12-06 00:00:00

  • Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects.

    abstract::BACKGROUND Human herpesvirus 2 (HHV-2) have DNA genome with a limited genetic variability and have been classified into two clades. OBJECTIVES To identify and characterise six HHV-2 isolates derived from Brazilian women. METHODS HHV-2 isolates were performed polymerase chain reaction (PCR) and sequencing of 2250 pb of...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180328

    authors: Lima LRP,Araújo NA,Guterres A,Pilotto JH,Niel C,Paula VS

    更新日期:2018-12-03 00:00:00

  • Comparative genomics reveals diverse capsular polysaccharide synthesis gene clusters in emerging Raoultella planticola.

    abstract::Raoultella planticola is an emerging zoonotic pathogen that is associated with rare but life-threatening cases of bacteremia, biliary tract infections, and urinary tract infections. Moreover, increasing antimicrobial resistance in the organism poses a potential threat to public health. In spite of its importance as a ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180192

    authors: Huang YT,Chuang WY,Ho BC,Wu ZY,Kuo RC,Ko M,Liu PY

    更新日期:2018-08-27 00:00:00

  • Structural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assembly.

    abstract::The biochemical pathways involved in nicotinamide adenine dinucleotide (NAD) biosynthesis converge at the enzymatic step catalysed by nicotinamide mononucleotide adenylyltransferase (NMNAT, EC: 2.7.7.1). The majority of NMNATs are assembled into homo-oligomeric states that comprise 2-6 subunits. Recently, the NMNAT of...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760180073

    authors: Contreras-Rodríguez LE,Marin-Mogollon CY,Sánchez-Mejía LM,Ramírez-Hernández MH

    更新日期:2018-07-10 00:00:00

  • NS1 codon usage adaptation to humans in pandemic Zika virus.

    abstract:BACKGROUND:Zika virus (ZIKV) was recognised as a zoonotic pathogen in Africa and southeastern Asia. Human infections were infrequently reported until 2007, when the first known epidemic occurred in Micronesia. After 2013, the Asian lineage of ZIKV spread along the Pacific Islands and Americas, causing severe outbreaks ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170385

    authors: Freire CCM,Palmisano G,Braconi CT,Cugola FR,Russo FB,Beltrão-Braga PC,Iamarino A,Lima Neto DF,Sall AA,Rosa-Fernandes L,Larsen MR,Zanotto PMA

    更新日期:2018-05-10 00:00:00

  • Successes and failures of sixty years of vector control in French Guiana: what is the next step?

    abstract::Since the 1940s, French Guiana has implemented vector control to contain or eliminate malaria, yellow fever, and, recently, dengue, chikungunya, and Zika. Over time, strategies have evolved depending on the location, efficacy of the methods, development of insecticide resistance, and advances in vector control techniq...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章,评审

    doi:10.1590/0074-02760170398

    authors: Epelboin Y,Chaney SC,Guidez A,Habchi-Hanriot N,Talaga S,Wang L,Dusfour I

    更新日期:2018-03-12 00:00:00

  • Lutzomyia umbratilis from an area south of the Negro River is refractory to in vitro interaction with Leishmania guyanensis.

    abstract:BACKGROUND:Lutzomyia umbratilis, the vector for Leishmania guyanensis in northern South America, has been found naturally infected with L. guyanensis only in areas north of the Negro and Amazon rivers. While populations of this sand fly species are also found in areas south of these rivers, these populations have never...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170425

    authors: Soares RP,Nogueira PM,Secundino NF,Marialva EF,Ríos-Velásquez CM,Pessoa FAC

    更新日期:2018-03-01 00:00:00

  • First detection of dengue virus in the saliva of immunocompetent murine model.

    abstract::The lack of an experimental animal model for the study of dengue pathogenesis is a limiting factor for the development of vaccines and drugs. In previous studies, our group demonstrated the susceptibility of BALB/c mice to infection by dengue virus (DENV) 1 and 2, and the virus was successfully isolated in several org...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170208

    authors: Rasinhas ADC,Silva MAND,Caldas GC,Jácome FC,Leonardo R,Santos FBD,Nunes PCG,Barth OM,Barreto-Vieira DF

    更新日期:2018-02-05 00:00:00

  • Anophelines species and the receptivity and vulnerability to malaria transmission in the Pantanal wetlands, Central Brazil.

    abstract::BACKGROUND Studies on malaria vectors in the Pantanal biome, Central Brazil, were conducted more than half a century ago. OBJECTIVES To update anopheline records and assess receptivity and vulnerability to malaria transmission. METHODS Five-day anopheline collections were conducted bimonthly in Salobra, Mato Grosso do...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170175

    authors: Marinho-E-Silva M,Sallum MAM,Rosa-Freitas MG,Lourenço-de-Oliveira R,Silva-do-Nascimento TF

    更新日期:2018-02-01 00:00:00

  • ERRATUM: Structural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assembly".

    abstract::[This corrects the article doi: 10.1590/0074-02760180073]. ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章,已发布勘误

    doi:10.1590/0074-02760180073er

    authors:

    更新日期:2018-01-01 00:00:00

  • Acute Chagas disease in the state of Pará, Amazon Region: is it increasing?

    abstract::Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian Notifiable Diseases Information S...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170298

    authors: Santos VRCD,Meis J,Savino W,Andrade JAA,Vieira JRDS,Coura JR,Junqueira ACV

    更新日期:2018-01-01 00:00:00

  • Evaluation of melanin production by Sporothrix luriei.

    abstract::There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170339

    authors: Cruz ILR,Figueiredo-Carvalho MHG,Zancopé-Oliveira RM,Almeida-Paes R

    更新日期:2018-01-01 00:00:00

  • Improved reverse transcription-polymerase chain reaction assay for the detection of flaviviruses with semi-nested primers for discrimination between dengue virus serotypes and Zika virus.

    abstract::BACKGROUND The genus Flavivirus includes a variety of medically important viruses, including dengue virus (DENV) and Zika virus (ZIKV), which are most prevalent in Brazil. Because the clinical profile of patients affected by different DENV serotypes or ZIKV may be similar, the development of new methods that facilitat...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170393

    authors: Nunes AR,Alves BEB,Pereira HW,Nascimento YM,Morais IC,Fernandes JV,Araújo JM,Lanza DC

    更新日期:2018-01-01 00:00:00

  • Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae.

    abstract:BACKGROUND:The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. OBJECTIVE:The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local population in five ...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170117

    authors: Arraes MLBM,Holanda MV,Lima LNGC,Sabadia JAB,Duarte CR,Almeida RLF,Kendall C,Kerr LRS,Frota CC

    更新日期:2017-12-01 00:00:00

  • Construction of Mycobacterium tuberculosis cdd knockout and evaluation of invasion and growth in macrophages.

    abstract::Cytidine deaminase (MtCDA), encoded by cdd gene (Rv3315c), is the only enzyme identified in nucleotide biosynthesis pathway of Mycobacterium tuberculosis that is able to recycle cytidine and deoxycytidine. An M. tuberculosis knockout strain for cdd gene was obtained by allelic replacement. Evaluation of mRNA expressio...

    journal_title:Memorias do Instituto Oswaldo Cruz

    pub_type: 杂志文章

    doi:10.1590/0074-02760170105

    authors: Villela AD,Rodrigues-Junior VS,Pinto AFM,Falcão VCA,Sánchez-Quitian ZA,Eichler P,Bizarro CV,Basso LA,Santos DS

    更新日期:2017-11-01 00:00:00

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