FLI1 gene influences lesion size and skin test may predict therapeutic response in cutaneous leishmaniasis.

abstract：:BACKGROUND The main strategy to control human malaria still relies on specific drug treatment, limited now by Plasmodium falciparum-resistant parasites, including that against artemisinin derivatives. Despite the large number of active compounds described in the literature, few of them reached full development against...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Penna-Coutinho J,Aguiar AC,Krettli\/ AU

更新日期：2018-12-06 00:00:00

abstract：:The alpha-glycerophosphate dehydrogenase (alpha-GPDH) activity in flight muscles of Panstrongylus megistus and Triatoma sordida, vectors of Chagas disease in Brazil, was studied. Both species showed higher enzymatic activities in fliers than in non-fliers insects. T. sordida exhibited a higher proportion of flier inse...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Soares RP,Santoro MM

更新日期：2000-09-01 00:00:00

abstract：:A 19-month mark-release-recapture study of Neotoma micropus with sequential screening for Leishmania mexicana was conducted in Bexar County, Texas, USA. The overall prevalence rate was 14.7% and the seasonal prevalence rates ranged from 3.8 to 26.7%. Nine incident cases were detected, giving an incidence rate of 15.5/...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Raymond RW,McHugh CP,Witt LR,Kerr SF

更新日期：2003-03-01 00:00:00

abstract：:Host lipids have been implicated in the pathogenesis of Toxoplasma gondii infection. To determine if Toxoplasma infection influences the lipid status in the normal host, we assessed serum lipids of Swiss-Webster mice during infection with the BGD-1 strain (type-2) at a series of time points. Mice were bled at days zer...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Milovanović I,Vujanić M,Klun I,Bobić B,Nikolić A,Ivović V,Trbovich AM,Djurković-Djaković O

更新日期：2009-03-01 00:00:00

abstract：:This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients. Immunological evaluation was performed by measurement of secreted cytokines (interleukin IL-5, IL-10, IL-13, interferon-gamm...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Magalhães A,Miranda DG,Miranda RG,Araújo MI,Jesus AA,Silva A,Santana LB,Pearce E,Carvalho EM,Jesus AR

更新日期：2004-01-01 00:00:00

abstract：:A vaccination campaign against pandemic influenza A (H1N1)pdm09 was held in Brazil in March 2010, using two types of monovalent split virus vaccines: an AS03-adjuvanted vaccine and a non-adjuvanted vaccine. We compared the reactogenicity of the vaccines in health professionals from a Clinical Research Institute in Rio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cerbino-Neto J,Santos AT,Gouvea MI,Pedro RS,Ramos GV,Guaraldo L,Werneck GL

更新日期：2012-11-01 00:00:00

abstract：:A study of crepuscular and night-biting mosquitoes was conducted at remote settlements along the Padauiri River, middle Negro River, state of Amazonas, Brazil. Collections were performed with human bait and a CDC-light trap on three consecutive days per month from June 2003-May 2004. In total, 1,203 h of collection we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Suárez-Mutis MC,Fé NF,Alecrim W,Coura JR

更新日期：2009-02-01 00:00:00

abstract：:A major advance in our understanding of the natural history of Schistosoma haematobium-related morbidity has come through the introduction of the portable ultrasound machines for non-invasive examination of the kidneys and bladder. With the use of generators or battery packs to supply power in non-clinical field setti...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： King CH

更新日期：2002-01-01 00:00:00

abstract：:The subject of this conference reflects the scientific community's interest in seeking to understand the complex causal web whose various social, economic, and biological components interact in the production and reproduction of schistosomiasis and its control in relation to community participation. From the onset, th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbosa FS

更新日期：1995-03-01 00:00:00

abstract：:Acute infection with Trypanosoma cruzi results in intense myocarditis, which progresses to a chronic, asymptomatic indeterminate form. The evolution toward this chronic cardiac form occurs in approximately 30% of all cases of T. cruzi infection. Suppression of delayed type hypersensitivity (DTH) has been proposed as a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Thé TS,Portella RS,Guerreiro ML,Andrade SG

更新日期：2013-09-01 00:00:00

abstract：:A sylvatic Triatoma infestans DM (dark morph) population detected in the Bolivian Chaco was characterized and compared with various domestic ones. The degree of differentiation of DM was clearly within the T. infestans intra-specific level. Nevertheless marked chromatic and morphometric differences as well as differen...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Noireau F,Bastrenta B,Catalá S,Dujardin JP,Panzera F,Torres M,Perez R,Galvão C,Jurberg J

更新日期：2000-01-01 00:00:00

abstract：:A new species of planorbid mollusc, Plesiophysa dolichomastix (Greek dolichos = long, mastix = flagellum), collected from Lagoa da Pedra, municipality of Santa Rosa, state of Goiás, Brazil (15 degrees 01'S, 47 degrees 13'W) is described. It is indistinguishable by the shell characters from the five congeneric species ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Paraense WL

更新日期：2002-06-01 00:00:00

abstract：:Only one drug is currently available for the treatment and control of schistosomiasis and the increasing risk of selecting strains of schistosome that are resistant to praziquantel means that the development of new drugs is urgent. With this objective we have chosen to target the enzymes modifying histones and in part...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pierce RJ,Dubois-Abdesselem F,Caby S,Trolet J,Lancelot J,Oger F,Bertheaume N,Roger E

更新日期：2011-11-01 00:00:00

abstract：:The triatomine bug Triatoma infestans probably originated in Bolivia and dispersed passively over wide areas of South America, where it is the principal vector of Trypanosoma cruzi. In the region of its probable origin this species shows colonization in two different ecotopes, so that it may be encountered in sylvatic...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pires HH,Barbosa SE,Diotaiuti L

更新日期：2000-11-01 00:00:00

abstract：:Tissue invasion and pathology by Trypanosoma cruzi result from an interaction between parasite virulence and host immunity. Successive in vivo generations of the parasite select populations with increasing ability to invade the host. Conversely, prolonged in vitro selection of the parasite produces attenuated sublines...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Basombrío MA,Segura MA,Gómez L,Padilla M

更新日期：2000-01-01 00:00:00

abstract：:The kidney trematode Paratanaisia bragai is reported for the first time parasitizing the ring-necked pheasant (Phasianus colchicus L., 1758) and the pathological alterations associated to the parasitism are referred on the basis of 50 specimens of this bird from backyard flocks in 11 counties of the state of Rio de Ja...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gomes DC,Menezes RC,Tortelly R,Pinto RM

更新日期：2005-05-01 00:00:00

abstract：:Major emergency efforts are being mounted for each vector-borne disease epidemiological crisis anew, while knowledge about the biology of arthropods vectors is dwindling slowly but continuously, as is the number of field entomologists. The discrepancy between the rates of production of knowledge and its use and need f...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Casas J,Lazzari C,Insausti T,Launois P,Fouque F

更新日期：2016-11-01 00:00:00

abstract：:Toxicological and toxicogenetic effects of aqueous (tea) and hexanic fruit extract of Indigofera suffruticosa Mill. and hydroalcoholic root extract of Solanum agrarium Stendt. were evaluated in Balb C male mice intraperitoneally exposed. A hepatotoxic effect was observed just for animals treated with aqueous fruit ext...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ribeiro LR,Bautista AR,Silva AR,Sales LA,Salvadori DM,Maia PC

更新日期：1991-01-01 00:00:00

abstract：:The global malaria situation has scarcely improved in the last 100 years, despite major advances in our knowledge of the basic biology, epidemiology and clinical basis of the disease. Effective malaria control, leading to a significant decrease in the morbidity and mortality attributable to malaria, will require a mul...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Riley EM

更新日期：2000-01-01 00:00:00

abstract：:Preparations of simian rotavirus SA11 maintained in different laboratories were compared with each other by polyacrylamide gel electrophoresis of genomic RNA. Differences in the migration of genome segments 4, 5 and 7 allowed the classification of eight virus preparations into four electrophoretic types. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pereira HG,Gouvea VS,Fialho AM

更新日期：1986-10-01 00:00:00

abstract：:We evaluated the potential of Mesocyclops annulatus as a control agent of Aedes aegypti in La Plata city (Argentina). Mosquito larval survivorship due to predation by these copepods was estimated at weekly intervals during the oviposition period of A. aegypti. Mean weekly A. aegypti larval survivorship in cylindrical ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Marti GA,Micieli MV,Scorsetti AC,Liljesthröm G

更新日期：2004-08-01 00:00:00

abstract：:The principal vector of malaria in eastern Venezuela, Anopheles aquasalis, is exophagic and exophilic. Control using indoor insecticide house sprays has failed to lower the number of malaria cases. Therefore, studies were initiated in two villages of the eastern coastal state of Sucre to better understand this vector'...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Berti J,Zimmerman R,Amarista J

更新日期：1993-07-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of ongoing drug repurposing efforts for COVID-19 as well as discussing ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Senger MR,Evangelista TCS,Dantas RF,Santana MVDS,Gonçalves LCS,de Souza Neto LR,Ferreira SB,Silva-Junior FP

更新日期：2020-10-02 00:00:00

abstract：:A preliminary study of the pharmacokinetic parameters of t-Butylaminoethanethiol (TBAESH) was performed after administration of a single dose (35 mg/kg) either orally or intravenously. Plasma or blood samples were treated with dithiothreitol, perchloric acid and, after filtration, submitted to further purification wit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade MH,Freire AC,Nelson DL

更新日期：1990-07-01 00:00:00

abstract：:Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed. Dual infection by DENV-2 and DENV-3 was identified by type-specific indirect immunofluorescence assay and confirmed by reverse transcription polymerase chain rea...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Araújo FM,Nogueira RM,de Araújo JM,Ramalho IL,Roriz ML,de Melo ME,Coelho IC

更新日期：2006-12-01 00:00:00

abstract：:We used a slide culture technique to detect tubercle bacilli surviving in sputum smears (n=46) after conventional heat fixation and Ziehl-Neelsen staining. In all heat-fixed sputum smears, tubercle bacilli survived after time 0 (n=22), 24 h (n=7), 48 h (n=7), 72 h (n=4), and seven days (n=6). None of the stained sputu...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardoso CL,Giacomelli LR,Helbel C,Sant'Ana JJ,Martins FM,Barreto AM

更新日期：2001-02-01 00:00:00

abstract：:Triatoma nitida was found in 14 (0.4%) out of 3,726 houses located in six departments across Guatemala, which were surveyed from 1994 to 1998 by the man-hour collection method. Compared to previous information, the distribution of T. nitida in Guatemala has increased from five to nine departments; the species is prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Monroy C,Bustamante DM,Rodas A,Rosales R,Mejía M,Tabaru Y

更新日期：2003-01-01 00:00:00

abstract：:Nitroarylidenemalononitriles and their cyanoacetamide derivatives with remarkable anti-epimastigote properties, were synthesized attempting to obtain new 3,5-diamino-4-(5'-nitroarylidene)-4H-thiadiazine 1,1-dioxide derivatives, which in previous reports had shown anti-Trypanosoma cruzi activity. Tests to evaluate the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Muelas-Serrano S,Le-Senne A,Fernandez-Portillo C,Nogal JJ,Ochoa C,Gomez-Barrio A

更新日期：2002-06-01 00:00:00

abstract：:The ultrastructure of endogenous stages of Eimeria ninakohlyakimovae was observed in epithelial cells of cecum and colon crypts from a goat experimentally infected with 2.0 x 10(5) oocysts/kg. The secondary meronts developed above the nucleus of the host cell. The nucleus first divides and merozoites then form on the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vieira LS,Lima JD,Ribeiro MF,Bozzi IA,Camargos ER

更新日期：1997-07-01 00:00:00

abstract：:Studies were conducted to determine the selection of humans, chickens and rabbits by Culicidae in three different environments in the province of Chaco, Argentina. Mosquitoes were collected fortnightly using cylindrical metal traps containing animal bait (chickens and rabbits). The mosquitoes were collected between Ju...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Stein M,Zalazar L,Willener JA,Almeida FL,Almirón WR

更新日期：2013-08-01 00:00:00