Abdominal angiostrongyliasis can be diagnosed with a immunochromatographic rapid test with recombinant galactin from Angiostrongylus cantonensis.

Abstract:

:Angiostrongylus costaricensis is the causative agent of abdominal angiostrongyliasis, a zoonotic infection that may produce severe eosinophilic enterocolitis or hepatitis in humans. Parasites are usually not released in stools and serology has an important role in diagnosis. Since cross-reactivity is demonstrated between A. costaricensis and another metastrongylid worm, A. cantonensis, we tested heterologous recombinant galectin as a probe in an immunochromatographic rapid diagnostic test (ICT-RDT) for detection of anti-A. costaricensis antibodies. Almost all (11/12) positive control sera from A. costaricensis infected patients were positive at ICT RDT. These are preliminary indications that r-galectin ICT-RDT is useful for diagnosing A. costaricensis infection.

journal_name

Mem Inst Oswaldo Cruz

authors

Graeff-Teixeira C,Pascoal VF,Rodriguez R,Morassutti AL,Intapan PM,Maleewong W

doi

10.1590/0074-02760200201

subject

Has Abstract

pub_date

2020-09-21 00:00:00

pages

e200201

eissn

0074-0276

issn

1678-8060

pii

S0074-02762020000100419

journal_volume

115

pub_type

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