听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览INTERNATIONAL IMMUNOLOGY期刊下所有文献
  • Interleukin 6 in inflammation, autoimmunity and cancer.

    abstract::Interleukin 6 (IL-6) is involved both in immune responses and in inflammation, hematopoiesis, bone metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely related to chronic inflammatory diseases, autoimmune diseases and cancer) and even in the cytokine storm of corona virus disease 201...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxaa078

    authors: Hirano T

    更新日期:2020-12-18 00:00:00

  • Lipid mediators and sterile inflammation in ischemic stroke.

    abstract::Stroke is one of the major causes of lethality and disability, yet few effective therapies have been established for ischemic stroke. Inflammation in the ischemic brain is induced by the infiltration and subsequent activation of immune cells. Loss of cerebral blood flow and ischemic brain-cell death trigger the activa...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxaa027

    authors: Nakamura A,Otani K,Shichita T

    更新日期:2020-10-20 00:00:00

  • IL-1α released from oral epithelial cells upon candidalysin exposure initiates an early innate epithelial response.

    abstract::Candida albicans is a commensal fungus that predominantly resides on mucosal surfaces and can cause lethal systemic infection when the host defense is compromised. Candidalysin is a cytolytic peptide toxin produced by C. albicans hyphae that is essential for mucosal tissue damage and is believed to contribute to the e...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxaa070

    authors: Hanaoka M,Domae E

    更新日期:2020-10-10 00:00:00

  • Increased levels of plasma nucleotides in patients with rheumatoid arthritis.

    abstract::Novel biomarkers of rheumatoid arthritis (RA), in addition to antibodies against cyclic citrullinated peptides, are required. Metabolome analysis is a promising approach to identify metabolite biomarkers for clinical diagnosis. We adopted a comprehensive nontargeted metabolomics approach combining capillary electropho...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxaa059

    authors: Kishikawa T,Maeda Y,Nii T,Arase N,Hirata J,Suzuki K,Yamamoto K,Masuda T,Ogawa K,Tsuji S,Matsushita M,Matsuoka H,Yoshimura M,Tsunoda S,Ohshima S,Narazaki M,Ogata A,Saeki Y,Inohara H,Kumanogoh A,Takeda K,Okada Y

    更新日期:2020-08-31 00:00:00

  • Danger-associated metabolic modifications during bacterial infection of macrophages.

    abstract::In this review, we propose that certain modifications in cellular metabolism might function as danger signals triggering inflammasome-mediated immune responses. We propose to call them danger-associated metabolic modifications (DAMMs). As intracellular bacteria can actively modulate macrophage metabolism for their ben...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxaa035

    authors: Dramé M,Buchrieser C,Escoll P

    更新日期:2020-06-26 00:00:00

  • The spectrum of macrophage activation by immunometabolism.

    abstract::Macrophages are heterogeneous and plastic, and play several diverse functions in immune responses. Emerging data provide evidence of multiple roles for metabolic pathways in the control of macrophage effector functions. The diverse functions of macrophages are categorized into two main subsets: classical activated mac...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxaa017

    authors: Kang S,Kumanogoh A

    更新日期:2020-06-26 00:00:00

  • Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intra-epithelial lymphocytes in the intestine.

    abstract::Interleukin-15 (IL-15) is a cytokine critical for maintenance of intestinal intra-epithelial lymphocytes (IELs), especially CD8αα + IELs (CD8αα IELs). In the intestine, IL-15 is produced by intestinal epithelial cells (IECs), blood vascular endothelial cells (BECs) and hematopoietic cells. However, the precise role of...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxz082

    authors: Zhu Y,Cui G,Miyauchi E,Nakanishi Y,Mukohira H,Shimba A,Abe S,Tani-Ichi S,Hara T,Nakase H,Chiba T,Sehara-Fujisawa A,Seno H,Ohno H,Ikuta K

    更新日期:2020-05-08 00:00:00

  • Characterization of the developmental landscape of murine RORγt+ iNKT cells.

    abstract::Invariant natural killer T (iNKT) cells expressing the retinoic acid receptor-related orphan receptor γt (RORγt) and producing IL-17 represent a minor subset of CD1d-restricted iNKT cells (iNKT17) in C57BL/6J (B6) mice. We aimed in this study to define the reasons for their low distribution and the sequence of events ...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxz064

    authors: Klibi J,Li S,Amable L,Joseph C,Brunet S,Delord M,Parietti V,Jaubert J,Marie J,Karray S,Eberl G,Lucas B,Toubert A,Benlagha K

    更新日期:2020-02-07 00:00:00

  • Differential role of MyD88 signaling in Streptococcus suis serotype 2-induced systemic and central nervous system diseases.

    abstract::Streptococcus suis serotype 2 is an important porcine bacterial pathogen and a zoonotic agent responsible for sudden death, septic shock and meningitis, with exacerbated inflammation being a hallmark of the systemic and central nervous system (CNS) infections. However, S. suis serotype 2 strains are genetically and ph...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxz033

    authors: Auger JP,Benoit-Biancamano MO,Bédard C,Segura M,Gottschalk M

    更新日期:2019-10-16 00:00:00

  • Prostanoids and leukotrienes in the pathophysiology of atopic dermatitis and psoriasis.

    abstract::Lipid mediators, such as prostanoids and leukotrienes (LTs), exert a range of actions through their own receptors on cell surfaces in various pathophysiological conditions. It has been reported that the production of prostanoids and LTs is significantly elevated in the skin lesions of some chronic inflammatory skin di...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxy087

    authors: Honda T,Kabashima K

    更新日期:2019-08-23 00:00:00

  • Gp49B is a pathogenic marker for auto-antibody-producing plasma cells in lupus-prone BXSB/Yaa mice.

    abstract::AbstractImmune homeostasis is critically regulated by the balance between activating and inhibitory receptors expressed on various immune cells such as T and B lymphocytes, and myeloid cells. The inhibitory receptors play a fundamental role in the immune checkpoint pathway, thus maintaining peripheral tolerance. We re...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxz017

    authors: Wong YL,Su MT,Sugahara-Tobinai A,Itoi S,Kezuka D,Endo S,Inui M,Takai T

    更新日期:2019-05-21 00:00:00

  • FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules.

    abstract::Natural killer (NK) cells are a major FcγRIIIA-expressing lymphocyte population that mediate antibody-dependent cellular cytotoxicity. Although NK cells are critical for immunity against viruses and tumors, they are also activated in the joints of patients with rheumatoid arthritis (RA) and may be involved in disease ...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxz010

    authors: Shimizu Y,Kohyama M,Yorifuji H,Jin H,Arase N,Suenaga T,Arase H

    更新日期:2019-04-26 00:00:00

  • Kit-independent mast cell adhesion mediated by Notch.

    abstract::Kit/CD117 plays a crucial role in the cell-cell and cell-matrix adhesion of mammalian mast cells (MCs); however, it is unclear whether other adhesion molecule(s) perform important roles in the adhesion of MCs. In the present study, we show a novel Kit-independent adhesion mechanism of mouse cultured MCs mediated by No...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxy067

    authors: Murata A,Hikosaka M,Yoshino M,Zhou L,Hayashi SI

    更新日期:2019-02-15 00:00:00

  • Recent progress in organoid culture to model intestinal epithelial barrier functions.

    abstract::The intestinal epithelium not only acts as the physical structure that separates the intestinal lumen from the body but also actively participates in intestinal barrier functions. In the past decade, significant progress has been made in the development of culture technologies to maintain intestinal epithelial cells (...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxy065

    authors: Nakamura T

    更新日期:2019-02-06 00:00:00

  • Regulation and role of the transcription factor IRF5 in innate immune responses and systemic lupus erythematosus.

    abstract::The transcription factor interferon regulatory factor-5 (IRF5) plays an important role in innate immune responses via the TLR-MyD88 (Toll-like receptor - myeloid differentiation primary response 88) pathway. IRF5 is also involved in the pathogenesis of the autoimmune disease systemic lupus erythematosus (SLE). Recent ...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxy032

    authors: Ban T,Sato GR,Tamura T

    更新日期:2018-10-29 00:00:00

  • The role of immune cells in brain development and neurodevelopmental diseases.

    abstract::During brain development, the generation of neurons and glial cells is rigorously regulated by diverse mechanisms including the immune system. Dysfunction of the developing system results in the onset of neurodevelopmental disorders and psychological disorders. Recent studies have demonstrated that the immune system i...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxy041

    authors: Tanabe S,Yamashita T

    更新日期:2018-09-25 00:00:00

  • IgE repertoire and immunological memory: compartmental regulation and antibody function.

    abstract::It is now generally recognized that bone marrow is the survival niche for antigen-specific plasma cells with long-term immunological memory. These cells release antibodies into the circulation, needed to prime effector cells in the secondary immune response. These antibodies participate in the surveillance for antigen...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxy048

    authors: Gould HJ,Wu YB

    更新日期:2018-08-30 00:00:00

  • How to master the host immune system? Leishmania parasites have the solutions!

    abstract::Infection by protozoan parasites of the genus Leishmania results in the development of leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people worldwide. Leishmaniasis can have very different outcomes ranging from cutaneous lesions, mucosal lesions to visceralization depending on th...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxx075

    authors: Rossi M,Fasel N

    更新日期:2018-03-10 00:00:00

  • A pro-inflammatory role of Fcα/μR on marginal zone B cells in sepsis.

    abstract::Fc receptors play important roles for a wide array of immune responses. In contrast to the well-defined Fcγ and Fcε receptors, the molecular and functional characteristics of Fc receptors for IgA and IgM have remained incompletely understood for years. Recent progress has unveiled the characteristics of Fc receptors f...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxx059

    authors: Shibuya A,Honda SI,Shibuya K

    更新日期:2017-12-30 00:00:00

  • Expression of KIR2DS1 does not significantly contribute to NK cell cytotoxicity in HLA-C1/C2 heterozygous haplotype B donors.

    abstract::NK cells are functionally controlled by the killer immunoglobulin-like receptor (KIR) family that comprises inhibitory (iKIR) and activating (aKIR) members. Genetic association studies suggest that donors expressing aKIRs next to iKIRs will be superior donors in the setting of hematopoietic stem cell transplantation o...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxx052

    authors: Baltner K,Kübler A,Pal M,Balvociute M,Mezger M,Handgretinger R,André MC

    更新日期:2017-11-01 00:00:00

  • Antibody therapy for the management of severe asthma with eosinophilic inflammation.

    abstract::One of the characteristic features of asthma is chronic airway inflammation typically with eosinophil infiltration. Most asthmatics can be treated successfully with conventional treatment appropriate for their severity, but in some severe cases, asthma cannot be well controlled even with thorough treatment and this co...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxx045

    authors: Ohta K,Nagase H,Suzukawa M,Ohta S

    更新日期:2017-07-01 00:00:00

  • Diversification of IgG effector functions.

    abstract::IgG is the major immunoglobulin class produced during an immune response against foreign antigens and efficiently provides protection through its bifunctional nature. While the Fab domains confer highly specific recognition of the antigen, the Fc domain mediates a wide range of effector functions that modulate several...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxx025

    authors: Bournazos S,Ravetch JV

    更新日期:2017-07-01 00:00:00

  • Commercial rodent diets differentially regulate autoimmune glomerulonephritis, epigenetics and microbiota in MRL/lpr mice.

    abstract::The course and severity of lupus in spontaneous murine lupus models varies among laboratories, which may be due to variations in diet, housing and/or local environmental conditions. In this study, we investigated the influence of common rodent diets while keeping other factors constant. Female lupus-prone MRL/lpr (MRL...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxx033

    authors: Edwards MR,Dai R,Heid B,Cecere TE,Khan D,Mu Q,Cowan C,Luo XM,Ahmed SA

    更新日期:2017-06-01 00:00:00

  • Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.

    abstract::Immunoglobulin affinity maturation depends on somatic hypermutation (SHM) in immunoglobulin variable (IgV) regions initiated by activation-induced cytidine deaminase (AID). AID induces transition mutations by C→U deamination on both strands, causing C:G→T:A. Error-prone repairs of U by base excision and mismatch repai...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxx032

    authors: Eid MMA,Shimoda M,Singh SK,Almofty SA,Pham P,Goodman MF,Maeda K,Sakaguchi N

    更新日期:2017-05-01 00:00:00

  • Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.

    abstract::Immune tolerance in the lung is important for preventing hypersensitivity, such as allergic asthma. Maintenance of tolerance in the lung is established by coordinated activities of poorly understood cellular and molecular mechanisms, including participation of dendritic cells (DCs). We have previously identified DC ex...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxx011

    authors: Han D,Walsh MC,Kim KS,Hong SW,Lee J,Yi J,Rivas G,Choi Y,Surh CD

    更新日期:2017-02-01 00:00:00

  • Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury.

    abstract::Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are among the major causes of death worldwide due to acute inflammation in the lung. AT-rich interactive domain-containing 5a (Arid5a) is an RNA-binding protein involved in inflammatory autoimmune disease through post-transcriptional control of Il6...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxx004

    authors: Dubey PK,Masuda K,Nyati KK,-Uz Zaman MM,Chalise JP,Millrine D,Kai W,Ripley B,Kishimoto T

    更新日期:2017-02-01 00:00:00

  • Mycobacterium indicus pranii (Mw)-mediated protection against visceral leishmaniasis by reciprocal regulation of host dual-specificity phosphatases.

    abstract::Leishmania donovani resides within the host macrophages by dampening host defence mechanisms and thereby it modulates the host cell functions for its survival. Multiple host cell factors compete during the interplay between the host and the parasite. Roles for dual-specificity phosphatases (DUSPs) are implicated in va...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxw049

    authors: Parveen S,Bandhyopadhyay S,Das S,Majumdar SB,Jawed JJ,Chowdhury BP,Saha B,Majumdar S

    更新日期:2016-12-01 00:00:00

  • Antibody-secreting cells in respiratory tract tissues in the absence of eosinophils as supportive partners.

    abstract::Antibody-secreting cells (ASCs) in respiratory tract tissues provide a first line of defense against invading pathogens. These cells often secrete IgA that is efficiently transcytosed across epithelial barriers into the airway lumen where pathogens can be blocked at their point of entry. Previous literature has report...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxw035

    authors: Sealy RE,Surman SL,Vogel P,Hurwitz JL

    更新日期:2016-11-01 00:00:00

  • Immune checkpoint inhibition in ovarian cancer.

    abstract::Recent studies have shown that tumor cells acquire escape mechanisms to evade host immunity in the tumor microenvironment. Two key immune checkpoint pathways mediated by immunosuppressive co-signaling, the first via programmed cell death 1 (PD-1) and PD-1 ligand 1 (PD-1/PD-L1) and the second via CTLA-4 and B7 (CTLA-4/...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxw020

    authors: Hamanishi J,Mandai M,Konishi I

    更新日期:2016-07-01 00:00:00

  • CXCR6 regulates the recruitment of pro-inflammatory IL-17A-producing T cells into atherosclerotic aortas.

    abstract::The adaptive immune response is involved in the development and progression of atherosclerosis and IL-17A(+) cells play a role in this disease. Although elevated number of CD4(+) IL-17A(+) (Th17) and IL-17A(+)TCRγδ(+) T cells are found within murine atherosclerotic aortas and human plaques, the mechanisms governing IL...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxv068

    authors: Butcher MJ,Wu CI,Waseem T,Galkina EV

    更新日期:2016-05-01 00:00:00

  • Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis.

    abstract::Leptin, one of the typical adipokines, is reported to promote Th17 cell responses and to enhance production of proinflammatory cytokines. To clarify the role of leptin in the regulation of the IL-23/IL-17 axis and the development of kidney disease, we used a murine model of nephrotoxic serum (NTS) nephritis (NTN). She...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxv067

    authors: Goto K,Kaneko Y,Sato Y,Otsuka T,Yamamoto S,Goto S,Yamamoto K,Yamamoto T,Kawachi H,Madaio MP,Narita I

    更新日期:2016-04-01 00:00:00

  • IL-28B down-regulates regulatory T cells but does not improve the protective immunity following tuberculosis subunit vaccine immunization.

    abstract::Regulatory T cells (Tregs), which could be down-regulated by IL-28B, were reported to suppress T-cell-mediated immunity. The aim of this study was to investigate the role of IL-28B on the immune responses and protective efficacy of a tuberculosis (TB) subunit vaccine. First, a recombinant adenoviral vector expressing ...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxv061

    authors: Luo Y,Ma X,Liu X,Lu X,Niu H,Yu H,Bai C,Peng J,Xian Q,Wang Y,Zhu B

    更新日期:2016-02-01 00:00:00

  • Differentiation and diversity of subsets in group 1 innate lymphoid cells.

    abstract::NK cells were first identified in 1975 and represent the prototypical group 1 innate lymphoid cell (ILC). More recently, the discovery of new members of the ILC family has highlighted the complexity of this innate lymphoid lineage. Importantly, it has been recognized that different subsets exist within the group 1 ILC...

    journal_title:International immunology

    pub_type: 杂志文章,评审

    doi:10.1093/intimm/dxv051

    authors: Seillet C,Belz GT

    更新日期:2016-01-01 00:00:00

  • Anti-Semaphorin 3A neutralization monoclonal antibody prevents sepsis development in lipopolysaccharide-treated mice.

    abstract::Semaphorin 3A (Sema3A), originally identified as a potent growth cone collapsing factor in developing sensory neurons, is now recognized as a key player in immune, cardiovascular, bone metabolism and neurological systems. Here we established an anti-Sema3A monoclonal antibody that neutralizes the effects of Sema3A bot...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxv014

    authors: Yamashita N,Jitsuki-Takahashi A,Ogawara M,Ohkubo W,Araki T,Hotta C,Tamura T,Hashimoto S,Yabuki T,Tsuji T,Sasakura Y,Okumura H,Takaiwa A,Koyama C,Murakami K,Goshima Y

    更新日期:2015-09-01 00:00:00

  • Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity.

    abstract::Toll-like receptors (TLRs) traffic to distinct membranes for signaling. TLR7 and TLR9 recognize viral nucleic acids in the endosomes and induce robust anti-viral program. Signaling from these TLRs bifurcate at the level of distinct endosomal compartments, namely VAMP3(+) and LAMP(+) endosomes, to mediate the induction...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxv021

    authors: Hayashi K,Sasai M,Iwasaki A

    更新日期:2015-09-01 00:00:00

  • CD1d-dependent expansion of NKT follicular helper cells in vivo and in vitro is a product of cellular proliferation and differentiation.

    abstract::NKT follicular helper cells (NKTfh cells) are a recently discovered functional subset of CD1d-restricted NKT cells. Given the potential for NKTfh cells to promote specific antibody responses and germinal center reactions, there is much interest in determining the conditions under which NKTfh cells proliferate and/or d...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxv007

    authors: Rampuria P,Lang ML

    更新日期:2015-05-01 00:00:00

  • Regulation of T cell development by c-Cbl: essential role of Lck.

    abstract::A canonical pre-TCR/TCR signaling pathway critical for thymic T cell development involves sequential phosphorylation and signaling through Lck, Zap70, Lat and Slp76. However, we and others have previously reported that genomic deletion of c-Cbl (Cbl) partially or completely reverses the defects in thymic development i...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxu105

    authors: Chiang YJ,Hodes RJ

    更新日期:2015-05-01 00:00:00

  • Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes.

    abstract::Toll-like receptor 7 (TLR7) and TLR9 sense microbial single-stranded RNA (ssRNA) and ssDNA in endolysosomes. Nucleic acid (NA)-sensing in endolysosomes is thought to be important for avoiding TLR7/9 responses to self-derived NAs. Aberrant self-derived NA transportation to endolysosomes predisposes to autoimmune diseas...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxu086

    authors: Li X,Saitoh S,Shibata T,Tanimura N,Fukui R,Miyake K

    更新日期:2015-02-01 00:00:00

  • Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

    abstract::Toll-like receptors (TLRs) recognize a variety of microbial products and induce defense responses. Pathogen sensing by TLRs occurs either on the cell surface or in endolysosomes. TLR-dependent responses are greatly influenced by the site of pathogen sensing. TLR heterodimers TLR1/TLR2 and TLR2/TLR6 recognize tri- or d...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxu054

    authors: Motoi Y,Shibata T,Takahashi K,Kanno A,Murakami Y,Li X,Kasahara T,Miyake K

    更新日期:2014-10-01 00:00:00

  • Generation of induced pluripotent stem cell-derived mice by reprogramming of a mature NKT cell.

    abstract::NKT cells are characterized by their expression of an NKT-cell-specific invariant antigen-receptor α chain encoded by Vα14Jα18 gene segments. These NKT cells bridge the innate and acquired immune systems to mediate effective and augmented responses; however, the limited number of NKT cells in vivo hampers their analys...

    journal_title:International immunology

    pub_type: 杂志文章

    doi:10.1093/intimm/dxu057

    authors: Ren Y,Dashtsoodol N,Watarai H,Koseki H,Quan C,Taniguchi M

    更新日期:2014-10-01 00:00:00

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