abstract：:Social Robots are used in different contexts and, in healthcare, they are better known as Socially Assistive Robots. In the context of asthma, the use of Socially Assistive Robots has the potential to increase motivation and engagement to treatment. Other positive roles proposed for Socially Assistive Robots are to pr...

journal_title：Paediatric respiratory reviews

authors： Ferrante G,Vitale G,Licari A,Montalbano L,Pilato G,Infantino I,Augello A,La Grutta S

更新日期：2020-12-05 00:00:00

abstract：:Asthma is a common disease in paediatrics and adults with a significant morbidity, mortality, and financial burden worldwide. Asthma is now recognized as a heterogeneous disease and emerging clinical and laboratory research has elucidated understanding of asthma's underlying immunology. The future of asthma is classif...

journal_title：Paediatric respiratory reviews

authors： Gans MD,Gavrilova T

更新日期：2020-11-01 00:00:00

abstract：:The concept of personalised medicine is likely to revolutionise the treatment of adult obstructive sleep apnoea as a result of recent advances in the understanding of disease heterogeneity by identifying clinical phenotypes, pathophysiological endotypes, biomarkers and treatable traits. Children with the condition sho...

journal_title：Paediatric respiratory reviews

authors： Siriwardhana LS,Nixon GM,Horne RSC,Edwards BA

更新日期：2020-11-01 00:00:00

abstract：AIM:To describe the respiratory and nutritional supportive care and hospitalisations required in the real-world scenario in children with SMA type 1 treated with nusinersen. METHODS:Single-centre observational cohort study of children with SMA1 commencing nusinersen from November 2016 to September 2018. Motor, respira...

journal_title：Paediatric respiratory reviews

authors： Chen KA,Widger J,Teng A,Fitzgerald DA,D'Silva A,Farrar M

更新日期：2020-09-22 00:00:00

abstract：:Breaking the news to parents that their child has cystic fibrosis [CF] is most frequently given in the first few weeks of the baby's life as a result of newborn screening. This is optimal to reduce morbidity but can have a significant impact on the parents' mental wellbeing and the parent-child relationship. Parent fe...

journal_title：Paediatric respiratory reviews

authors： Bryon M

更新日期：2020-09-01 00:00:00

abstract：:Since January 2020, there has been a worldwide pandemic of COVID-19, caused by a novel coronavirus-severe acute respiratory syndrome coronavirus 2. The United States has been particularly affected, with the largest number of confirmed cases in a single country in the world. Healthcare systems for adults as well as chi...

journal_title：Paediatric respiratory reviews

authors： Jain PN,Finger L,Schieffelin JS,Zerr DM,Hametz PA

更新日期：2020-09-01 00:00:00

abstract：:Despite evidence showing an improvement in nutritional outcomes following diagnosis by newborn screening (NBS) for cystic fibrosis (CF), the impact on pulmonary outcomes has been less clear. In this review the approaches to measurement of early lung function and knowledge gained from NBS CF cohorts will be described. ...

journal_title：Paediatric respiratory reviews

authors： Davies G

更新日期：2020-08-20 00:00:00

abstract：:Polysomnography is an elaborate diagnostic test composed of numerous data-collecting sensors working concomitantly to aid in the evaluation of varied sleep disorders in all age groups. Polysomnography is the study of choice for the assessment of pediatric sleep-disordered breathing, including obstructive sleep apnea s...

journal_title：Paediatric respiratory reviews

authors： Stowe RC,Afolabi-Brown O

更新日期：2020-04-01 00:00:00

abstract：:Obesity is a significant public health problem worldwide, and it has been identified as an independent risk factor for asthma in both adults and children. Not only does obesity increase asthma risk, but it is also associated with decreased asthma-related quality of life, worsened symptoms and asthma control, increased...

journal_title：Paediatric respiratory reviews

authors： McLoughlin RF,Berthon BS,Wood LG

更新日期：2020-03-06 00:00:00

abstract：:The aim of this study was to review and synthesize the existing knowledge of the effects of ultrafine particles [UFPs] with a specific focus on children's health. An extensive literature search identified 16 studies fulfilling the criteria set for the review. One of the most important findings of the review was that, ...

journal_title：Paediatric respiratory reviews

authors： da Costa E Oliveira JR,Base LH,de Abreu LC,Filho CF,Ferreira C,Morawska L

更新日期：2019-11-01 00:00:00

abstract：:NICE produced a guideline for the diagnosis and management of CF (NG78) in October 2017. This paper describes the process of producing the guideline and highlights some of the areas covered by it, including ideas for further research and tools that can be used by purchasers to help improve CF care. ...

journal_title：Paediatric respiratory reviews

authors： Walshaw MJ

更新日期：2019-08-01 00:00:00

abstract：:Bronchiolitis is a common viral disease that significantly affects infants less than 12 months of age. The purpose of this review is to present a review of the current knowledge of the uses of respiratory support in the management of infants with bronchiolitis presenting to hospital. We electronically searched MEDLINE...

journal_title：Paediatric respiratory reviews

authors： Franklin D,Fraser JF,Schibler A

更新日期：2019-04-01 00:00:00

abstract：:Pediatric donation after circulatory death (pDCD) is an established pathway for organ donation. It remains, however, a relatively rare event worldwide, and most clinicians outside of the pediatric intensive care unit (PICU) are unfamiliar with it. The goal of this review is to introduce the processes and concepts of p...

journal_title：Paediatric respiratory reviews

authors： Weiss MJ,Sherry W,Hornby L

更新日期：2019-02-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD), also known as immotile-cilia syndrome, is a rare genetic disease that is inherited in an autosomal recessive manner. Several studies have explored certain aspects of PCD in the Arab world, yet much is still lacking in terms of identifying the different characteristics of this disease....

journal_title：Paediatric respiratory reviews

authors： Hammoudeh S,Gadelhak W,Janahi IA

更新日期：2019-02-01 00:00:00

abstract：:Outdoor air pollution is increasingly identified as a contributor to respiratory and cardiovascular disease. Pro-inflammatory particles and gases are inhaled deep into the lungs, and are associated with impaired lung growth and exacerbations of chronic respiratory diseases. The magnitude of these effects are of intere...

journal_title：Paediatric respiratory reviews

authors： Brugha R,Edmondson C,Davies JC

更新日期：2018-09-01 00:00:00

abstract：:Asthma is one of the commonest chronic conditions in children and can occasionally be fatal. Little has changed regarding the risk factors for children dying from asthma in the last 30 years. The majority of deaths from asthma occur in children from socio-economically disadvantaged backgrounds. These should be prevent...

journal_title：Paediatric respiratory reviews

authors： Herrera AM,Fitzgerald DA

更新日期：2018-06-01 00:00:00

abstract：:CFTR modulators are a class of drugs which directly target the defective CFTR protein in cystic fibrosis (CF), improving its function with resultant clinical improvements. Currently these drugs are confined to people with a limited selection of genetic mutations. New modulators are in development which will lead to th...

journal_title：Paediatric respiratory reviews

authors： Mitchell RM,Jones AM,Barry PJ

更新日期：2018-06-01 00:00:00

abstract：:It is reasonable to suggest that Telemedicine could help in the management of chronic diseases by giving patients more flexibility to remain at home with opportunities to forward electronic data to healthcare professionals, reduce hospital emergency attendances and reduce overall costs. The reality, particularly in cy...

journal_title：Paediatric respiratory reviews

authors： Lenney W

更新日期：2018-03-01 00:00:00

abstract：:Whilst substantial progress has been made in the treatment of cystic fibrosis, the disease still carries a significant burden in terms of symptoms, requirement for treatment and early mortality. The last decade has witnessed a new era in the development of small molecule drugs targeting the CFTR protein, which for the...

journal_title：Paediatric respiratory reviews

authors： Harman K,Dobra R,Davies JC

更新日期：2018-03-01 00:00:00

abstract：:Bronchiolitis is a common disease in infancy, mostly due to Respiratory Syncytial Virus and Rhinovirus. In addition to acute infection, viral bronchiolitis is responsible for sequelae including recurrent wheezing and asthma. The analysis of the viral characteristics and of the pathogenesis of the infection shows diffe...

journal_title：Paediatric respiratory reviews

authors： Vandini S,Calamelli E,Faldella G,Lanari M

更新日期：2017-09-01 00:00:00

abstract：:Significant improvement in the survival of patients with CF has been achieved in the last decades. The improved clinical status of the patients is mainly the result of a better understanding of the natural course of infection and inflammation in CF that has led to the implementation of strategies that increase the lif...

journal_title：Paediatric respiratory reviews

authors： Kerem E

更新日期：2017-09-01 00:00:00

abstract：:During airflight, cabins are pressurised to 8000ft (2438m) leading to an effective FiO2 of 0.15. This leads to a fall in oxygen saturation in all passengers, and especially those with underlying lung disease. The hypoxic challenge test using a body plethysmograph can predict a need for supplemental oxygen during airfl...

journal_title：Paediatric respiratory reviews

authors： Balfour-Lynn IM

更新日期：2017-01-01 00:00:00

abstract：:Air pollution exposure has increased extensively in recent years and there is considerable evidence that exposure to particulate matter can lead to adverse respiratory outcomes. The health impacts of exposure to air pollution during the prenatal period is especially concerning as it can impair organogenesis and organ ...

journal_title：Paediatric respiratory reviews

authors： Korten I,Ramsey K,Latzin P

更新日期：2017-01-01 00:00:00

abstract：:The obstructive sleep apnoea syndrome (OSAS) is common in children and results in several complications when untreated. Considering that children are undergoing important brain development, recent research has focused on neurocognitive and behavioural (NCB) complications of OSAS. Studies have shown that treatment of p...

journal_title：Paediatric respiratory reviews

authors： Konstantinopoulou S,Tapia IE

更新日期：2016-09-01 00:00:00

abstract：:A systematic review was performed (i) to describe the reported overall rate of progression of CF lung disease quantified as FEV1%predicted decline with age, (ii) to summarise identified influencing risk factors and (iii) to review methods used to analyse CF lung disease progression data. A search of publications provi...

journal_title：Paediatric respiratory reviews

authors： Harun SN,Wainwright C,Klein K,Hennig S

更新日期：2016-09-01 00:00:00

abstract：:There have been major advances in the surgery for oesophageal atresia (OA) and tracheo-oesophageal fistula(TOF) with survival now exceeding 90%. The standard open approach to OA and distal TOF has been well described and essentially unchanged for the last 60 years. Improved survival in recent decades is most attributa...

journal_title：Paediatric respiratory reviews

authors： Teague WJ,Karpelowsky J

更新日期：2016-06-01 00:00:00

abstract：:Primary Ciliary Dyskinesia (PCD) is an autosomal recessive genetic condition affecting the function of motile cilia. The upper respiratory tract is lined with ciliated epithelium and hence a hallmark of PCD is the development, from the neonatal period onwards, of persisting secretion retention and suppurative infectio...

journal_title：Paediatric respiratory reviews

authors： Morgan LC,Birman CS

更新日期：2016-03-01 00:00:00

abstract：:Pediatric pulmonary arterial hypertension (PAH) is an uncommon disease that can occur in neonates, infants, and children, and is associated with high morbidity and mortality. Despite advances in treatment strategies over the last two decades, the underlying structural and functional changes to the pulmonary arterial c...

journal_title：Paediatric respiratory reviews

authors： Lohani O,Colvin KL,Yeager ME

更新日期：2015-09-01 00:00:00

abstract：:Despite fundamental advances in the research on respiratory syncytial virus (RSV) since its initial identification almost 60 years ago, recurring failures in developing vaccines and pharmacologic strategies effective in controlling the infection have allowed RSV to become a leading cause of global infant morbidity and...

journal_title：Paediatric respiratory reviews

authors： Brown PM,Schneeberger DL,Piedimonte G

更新日期：2015-09-01 00:00:00

abstract：:Assessing chest wall motion is a basic and vital component in managing the child with respiratory problems, whether these are due to pathology in the lungs, airways, chest wall or muscles. Since the 1960s, clinical assessment has been supplemented with an ever-growing range of technological options for measuring chest...

journal_title：Paediatric respiratory reviews

authors： Seddon P

更新日期：2015-01-01 00:00:00

abstract：:Many factors have been implicated in SIDS cases including environmental influences such as sleeping arrangements and smoking. Most recently, cardiac abnormalities have been hypothesised to play a role in some cases, particularly the primary genetic arrhythmogenic disorders such as familial long QT syndrome (LQTS). Bot...

journal_title：Paediatric respiratory reviews

authors： Sweeting J,Semsarian C

更新日期：2014-12-01 00:00:00

abstract：:The thorax consists of the rib cage and the respiratory muscles. It houses and protects the various intrathoracic organs such as the lungs, heart, vessels, esophagus, nerves etc. It also serves as the so-called "respiratory pump" that generates the movement of air into the lungs while it prevents their total collapse ...

journal_title：Paediatric respiratory reviews

authors： Koumbourlis AC

更新日期：2014-09-01 00:00:00

abstract：:Despite being the most widely used and vital therapy in neonatology, optimal strategies for the use of oxygen in preterm infants remain controversial. Achieving the balance between attaining adequate tissue oxygenation and avoiding oxygen toxicity is challenging. There remains a paucity of clear evidence based guidanc...

journal_title：Paediatric respiratory reviews

authors： Cherian S,Morris I,Evans J,Kotecha S

更新日期：2014-06-01 00:00:00

abstract：:During the first year of life and particularly the first 6 months autonomic control of the cardio-respiratory system is still undergoing maturation and infants are at risk of cardio-respiratory instability. These instabilities are most marked during sleep, which is important as infants spend the majority of each 24 ho...

journal_title：Paediatric respiratory reviews

authors： Horne RS

更新日期：2014-06-01 00:00:00

abstract：:Public awareness of the impact of air quality on health is increasing worldwide. Indoor and outdoor air pollutants impair children's growing lungs, and increase the risk of respiratory infections. In many cities, children face indoor air pollution from fuels used for cooking and heating, as well as outdoor pollution f...

journal_title：Paediatric respiratory reviews

authors： Brugha R,Grigg J

更新日期：2014-06-01 00:00:00

abstract：:Cystic fibrosis (CF) respiratory infection is characterised by the presence of typical human bacterial pathogens such as Pseudomonas aeruginosa, Haemophilus influenzae and Staphylococcus aureus. Less typical pathogens such as Burkholderia, Stenotrophomonas, Achromobacter, Pandorea and Ralstonia have emerged as problem...

journal_title：Paediatric respiratory reviews

authors： Mahenthiralingam E

更新日期：2014-06-01 00:00:00

abstract：:Conflict between the demands of the environment in which a child lives and the child's intrinsic sleep signature, produces stress-behaviour difficulties in the child. Distorted development, especially distorted brain development, often leads to distorted intrinsic sleep signatures. The sleep-behaviour outcome, arising...

journal_title：Paediatric respiratory reviews

authors： Nunn K

更新日期：2014-03-01 00:00:00

abstract：:Sickle cell disease (SCD), caused by a mutation in the β-globin gene HBB, is widely distributed in malaria endemic regions. Cardiopulmonary complications are major causes of morbidity and mortality. Hemoglobin SS (Hb SS) represents a large proportion of SCD in the Americas, United Kingdom, and certain regions of Afric...

journal_title：Paediatric respiratory reviews

authors： Saraf SL,Molokie RE,Nouraie M,Sable CA,Luchtman-Jones L,Ensing GJ,Campbell AD,Rana SR,Niu XM,Machado RF,Gladwin MT,Gordeuk VR

更新日期：2014-03-01 00:00:00

abstract：:Accumulating data suggest that prenatal compromises leading to intrauterine growth restriction (IUGR) increase the risk for respiratory deficiencies after birth. In this respect, a growing body of epidemiological evidence in infants, children and adults indicates that small for gestational (SGA) birth weight can adver...

journal_title：Paediatric respiratory reviews

authors： Briana DD,Malamitsi-Puchner A

更新日期：2013-12-01 00:00:00

abstract：:Pulmonary arterial (PA) hypertension in preterm infant is an important consequence of chronic lung disease of prematurity (CLD) arising mainly due to impaired alveolar development and dysregulated angiogenesis of the pulmonary circulation. Although PA pressure and resistance in these children normalise by school age, ...

journal_title：Paediatric respiratory reviews

authors： Poon CY,Edwards MO,Kotecha S

更新日期：2013-12-01 00:00:00