Abstract:
:Despite being the most widely used and vital therapy in neonatology, optimal strategies for the use of oxygen in preterm infants remain controversial. Achieving the balance between attaining adequate tissue oxygenation and avoiding oxygen toxicity is challenging. There remains a paucity of clear evidence based guidance for clinicians on safe oxygen saturation targets. What does seem apparent is that these targets vary over time in the life of a preterm infant. This article summarises the evidence behind current practice of oxygen monitoring and administration from the first few minutes after birth, through to the acute neonatal and later convalescent periods. Finally, we review the use of home oxygen for preterm infants with bronchopulmonary dysplasia including administration and weaning from domically home oxygen.
journal_name
Paediatr Respir Revjournal_title
Paediatric respiratory reviewsauthors
Cherian S,Morris I,Evans J,Kotecha Sdoi
10.1016/j.prrv.2012.12.003subject
Has Abstractpub_date
2014-06-01 00:00:00pages
135-41issue
2eissn
1526-0542issn
1526-0550pii
S1526-0542(12)00098-Xjournal_volume
15pub_type
杂志文章,评审abstract::Polysomnography is an elaborate diagnostic test composed of numerous data-collecting sensors working concomitantly to aid in the evaluation of varied sleep disorders in all age groups. Polysomnography is the study of choice for the assessment of pediatric sleep-disordered breathing, including obstructive sleep apnea s...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2019.09.009
更新日期:2020-04-01 00:00:00
abstract::Many factors have been implicated in SIDS cases including environmental influences such as sleeping arrangements and smoking. Most recently, cardiac abnormalities have been hypothesised to play a role in some cases, particularly the primary genetic arrhythmogenic disorders such as familial long QT syndrome (LQTS). Bot...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2014.09.006
更新日期:2014-12-01 00:00:00
abstract::There are hardly any controlled studies in paediatric tracheostomy care; instead, most established standards, procedures and details have been elaborated at the bedside by trial and error. Once the appropriate tube is chosen, tube care consists of tube change, fixation, management of secretions, humidification of insp...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2006.06.003
更新日期:2006-09-01 00:00:00
abstract::A systematic review was performed (i) to describe the reported overall rate of progression of CF lung disease quantified as FEV1%predicted decline with age, (ii) to summarise identified influencing risk factors and (iii) to review methods used to analyse CF lung disease progression data. A search of publications provi...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2016.03.002
更新日期:2016-09-01 00:00:00
abstract::The term "mucoactive agent" refers to any medication used to improve the clearance of airway secretions. It is not synonymous with the word "mucolytic" as this strictly means a drug that decreases the viscosity of secretions. In many cases, decreased viscosity will adversely affect cough transport. For this reason man...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2006.04.198
更新日期:2006-01-01 00:00:00
abstract::Newborn screening for cystic fibrosis remains controversial because there is still little agreement that prophylactic interventions provide substantial long-term benefits. In such situations, where there are some medical benefits and the costs are not prohibitive, it is important to consider the psychosocial implicati...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/s1526-0542(03)00086-1
更新日期:2003-12-01 00:00:00
abstract::NICE produced a guideline for the diagnosis and management of CF (NG78) in October 2017. This paper describes the process of producing the guideline and highlights some of the areas covered by it, including ideas for further research and tools that can be used by purchasers to help improve CF care. ...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2019.02.006
更新日期:2019-08-01 00:00:00
abstract::Increasing numbers of children and young adults are now receiving home ventilation. Whereas in some neuromuscular conditions the outcome and quality of life gains are clear cut; in others eg Spinal Muscular Atrophy Type I there are a few outcome studies with conflicting results and it is more difficult to balance the ...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2005.06.003
更新日期:2005-09-01 00:00:00
abstract::Pulmonary arterial (PA) hypertension in preterm infant is an important consequence of chronic lung disease of prematurity (CLD) arising mainly due to impaired alveolar development and dysregulated angiogenesis of the pulmonary circulation. Although PA pressure and resistance in these children normalise by school age, ...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2012.08.003
更新日期:2013-12-01 00:00:00
abstract::Advances in the elucidation of cystic fibrosis transmembrane regulator (CFTR) function have resulted in a greater understanding of the relationship between the CF gene defect and clinical disease. The clinical phenotype is influenced by the class of mutation and possibly by other modifier genes. CFTR regulates the vol...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1053/prrv.2000.0029
更新日期:2000-06-01 00:00:00
abstract::Air pollution exposure has increased extensively in recent years and there is considerable evidence that exposure to particulate matter can lead to adverse respiratory outcomes. The health impacts of exposure to air pollution during the prenatal period is especially concerning as it can impair organogenesis and organ ...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2016.08.008
更新日期:2017-01-01 00:00:00
abstract::There are multiple aetiologies for childhood bronchiectasis unrelated to cystic fibrosis. Some of these aetiologies, such as those predisposing to recurrent lung infections, e.g. immunodeficiencies, require treatment of the underlying condition and disease-specific pulmonary pathogens within the airway. Regardless of ...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章
doi:10.1016/j.prrv.2010.10.012
更新日期:2011-06-01 00:00:00
abstract::Asthma is a common disease in paediatrics and adults with a significant morbidity, mortality, and financial burden worldwide. Asthma is now recognized as a heterogeneous disease and emerging clinical and laboratory research has elucidated understanding of asthma's underlying immunology. The future of asthma is classif...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2019.08.002
更新日期:2020-11-01 00:00:00
abstract::The Clinical and Functional Translation of CFTR (CFTR2) project presents a novel approach to clinical and functional annotation of mutations identified in disease-causing genes. Phenotype and genotype information on approximately 40,000 cystic fibrosis (CF) patients were collected from registries and large clinics. Th...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章
doi:10.1016/j.prrv.2013.01.006
更新日期:2013-05-01 00:00:00
abstract::Bronchiolitis is a common disease in infancy, mostly due to Respiratory Syncytial Virus and Rhinovirus. In addition to acute infection, viral bronchiolitis is responsible for sequelae including recurrent wheezing and asthma. The analysis of the viral characteristics and of the pathogenesis of the infection shows diffe...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2016.11.006
更新日期:2017-09-01 00:00:00
abstract::Regular exercise and habitual physical activity are important for patients with cystic fibrosis (CF). Research has demonstrated the benefits of aerobic, anaerobic, and strength exercise training programs for health and quality of life, however, the CF patient is faced with unique barriers and challenges to participati...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2009.04.001
更新日期:2009-09-01 00:00:00
abstract::Obesity is a significant public health problem worldwide, and it has been identified as an independent risk factor for asthma in both adults and children. Not only does obesity increase asthma risk, but it is also associated with decreased asthma-related quality of life, worsened symptoms and asthma control, increased...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2020.02.007
更新日期:2020-03-06 00:00:00
abstract::Despite fundamental advances in the research on respiratory syncytial virus (RSV) since its initial identification almost 60 years ago, recurring failures in developing vaccines and pharmacologic strategies effective in controlling the infection have allowed RSV to become a leading cause of global infant morbidity and...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2015.05.005
更新日期:2015-09-01 00:00:00
abstract::During the first year of life and particularly the first 6 months autonomic control of the cardio-respiratory system is still undergoing maturation and infants are at risk of cardio-respiratory instability. These instabilities are most marked during sleep, which is important as infants spend the majority of each 24 ho...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2013.02.012
更新日期:2014-06-01 00:00:00
abstract::Asthma is a heterogeneous disease and it is therefore unrealistic to expect that inhaled corticosteroids (ICS) would be appropriate first line preventer therapy for all children with asthma. There is good theoretical and clinical trial evidence demonstrating that leukotriene receptor antagonists (LTRAs) are more effec...
journal_title:Paediatric respiratory reviews
pub_type: 评论,杂志文章
doi:10.1016/j.prrv.2011.05.008
更新日期:2011-12-01 00:00:00
abstract::Pediatric donation after circulatory death (pDCD) is an established pathway for organ donation. It remains, however, a relatively rare event worldwide, and most clinicians outside of the pediatric intensive care unit (PICU) are unfamiliar with it. The goal of this review is to introduce the processes and concepts of p...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2018.03.006
更新日期:2019-02-01 00:00:00
abstract::With the advent of improved antenatal imaging over the past 10 years, the diagnosis, assessment and management of congenital cystic lung abnormalities have changed. These were once considered the exclusive domain of the surgeon, who had the authority to operate on all congenital cystic lung abnormalities regardless of...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2006.10.001
更新日期:2007-03-01 00:00:00
abstract::Vocal cord dysfunction is characterised by paradoxical vocal cord adduction that occurs during inspiration, resulting in symptoms of dyspnoea, wheeze, chest or throat tightness and cough. Although the condition is well described in children and adults, confusion with asthma often triggers the use of an aggressive trea...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2007.05.004
更新日期:2007-06-01 00:00:00
abstract::The anatomical and functional development of the lung appears especially vulnerable to a whole range of insults during gestation and the first few years of life. A significant proportion of adult lung disease originates in utero or early infancy. Most publications on this topic are descriptive retrospective studies. A...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/s1526-0542(02)00311-1
更新日期:2003-03-01 00:00:00
abstract::The major morbidity and mortality associated with cerebral palsy (CP) relates to respiratory compromise. This manifests through repeated pulmonary aspiration, airway colonization with pathogenic bacteria, the evolution of bronchiectasis and sleep disordered breathing. An accurate assessment involving a multidisciplina...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2008.10.003
更新日期:2009-03-01 00:00:00
abstract::Since preschool wheezing is the common expression of several heterogeneous disorders, identification of children at risk for persistent asthma is particularly challenging. To date, efforts to predict the outcome of preschool wheeze have mainly relied on predictive rules consisting of simple clinical and laboratory par...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2012.08.004
更新日期:2013-03-01 00:00:00
abstract::The thorax consists of the rib cage and the respiratory muscles. It houses and protects the various intrathoracic organs such as the lungs, heart, vessels, esophagus, nerves etc. It also serves as the so-called "respiratory pump" that generates the movement of air into the lungs while it prevents their total collapse ...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2013.12.003
更新日期:2014-09-01 00:00:00
abstract::Foreign body aspiration is a common accident in children and represents an important cause of morbidity and mortality. Diagnosis of this condition demands a high degree of suspicion since physical examination and basic radiology exams have low sensitivity. It is more frequent in children younger than 3 years of age, p...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/s1526-0542(02)00265-8
更新日期:2002-12-01 00:00:00
abstract::Obese adolescents, particularly those with extreme obesity (body mass index > or =40 kg/m(2)), are developing serious medical complications at an unexpectedly high rate. As non-operative approaches to weight loss have shown less than optimal results, paediatric patients are increasingly seeking bariatric surgical inte...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:10.1016/j.prrv.2006.08.004
更新日期:2006-12-01 00:00:00
abstract::Respiratory viruses cause a number of clinical 'syndromes' in the intensive care unit with different viruses being able to produce similar clinical pictures. Our main presenting problems are upper airway (e.g. croup and tracheitis), lower airway with intrapulmonary shunt (e.g. bronchitis and pneumonia), lower airway w...
journal_title:Paediatric respiratory reviews
pub_type: 杂志文章,评审
doi:
更新日期:2003-09-01 00:00:00