abstract：OBJECTIVES:To analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective indigenous diet for management of this disorder. METHODS:This is a single-centre retrospective study. Fifteen patients from 14 kindreds with severe hypertriglyceridemia (more...

journal_title：Indian journal of pediatrics

authors： Kuthiroly S,Yesodharan D,Radhakrishnan N,Ganapathy A,Mannan AU,Hoffmann MM,Nampoothiri S

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To identify the burden of rotavirus acute gastroenteritis (AGE) and the genotypes presenting in the authors' area in the period after introduction of rotavirus vaccine in Universal Immunization Programme (UIP). METHODS:Children aged less than 5 y and presenting to hospital for the treatment of AGE were enrol...

journal_title：Indian journal of pediatrics

authors： Badur M,Pidugu VKR,Kasala L,Samarasimha Reddy N,Thiyagarajan V

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVE:To evaluate the epidemiology of rotavirus gastroenteritis in Haryana post-introduction of rotavirus vaccine. Expanded National rotavirus surveillance network in India reported high burden of rotavirus diarrhea in India. The Government of India introduced the monovalent rotavirus vaccine made in India by Bhara...

journal_title：Indian journal of pediatrics

authors： Dalal P,Gathwala G,Singh J,Nair NP,Thiyagarajan V

更新日期：2021-01-14 00:00:00

abstract：OBJECTIVES:In this pilot study, the authors developed and evaluated a working memory intervention (WMI) using a combination of mobile phone-based application and an activity booklet, among children with idiopathic generalized epilepsy. METHODS:Pre- and post-intervention cognitive evaluation at 8 wk included: subtests ...

journal_title：Indian journal of pediatrics

authors： Phakey N,Sharma S,Garg D,Mukherjee SB,Sapra S,Wadhawan AN,Shukla G

更新日期：2021-01-09 00:00:00

abstract：OBJECTIVE:To evaluate the concerns the parents have with the development of their children and related conditions and investigate how often these concerns are addressed at all levels of the healthcare system. Determining parental perceptions of these issues and highlighting missed opportunities is valuable for improvin...

journal_title：Indian journal of pediatrics

authors： Çelen Yoldaş T,Özmert EN,Bayazıt Y,Tanrıkulu B,Yetim H,Çakır B

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To describe the characteristics of Lophomonas blattarum infection in children based on a retrospective review of medical records data from Beijing Children's Hospital, Capital Medical University, China. METHODS:This study included 53 cases from July 2014 through December 2016. The data were tabulated and sta...

journal_title：Indian journal of pediatrics

authors： Ding Q,Shen K

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To study the new ISPAE guidelines in neonates with congenital hypothyroidism and present authors' experience in managing these neonates. METHODS:A retrospective review of all babies who were screened for congenital hypothyroidism in the institution over a period of 5 y was conducted. Details pertaining to ma...

journal_title：Indian journal of pediatrics

authors： Venugopalan L,Paranjyothi S,Sankaran A,Prasad HK,Murugesan G,Shanmughasundaram R

更新日期：2020-11-20 00:00:00

abstract：:Antimicrobial resistance is a key factor leading to emerging/ re-emerging infections. Rational antimicrobial therapy or antimicrobial stewardship is one of the important interventions to prevent emergence of resistance. Choosing correct empiric therapy is crucial not only to prevent antimicrobial resistance but also t...

journal_title：Indian journal of pediatrics

authors： Singhal T

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To identify risk factors and outcomes associated with early failure of nasal continuous positive airway pressure (CPAP) in premature infants with respiratory distress (RD). METHODS:This is a retrospective observational study of all the preterm infants with RD primarily supported on nasal CPAP and included i...

journal_title：Indian journal of pediatrics

authors： Murki S,Kandraju H,Oleti T,Saikiran,Gaddam P

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of low dose vasopressin on the hemodynamics of neonates with persistent pulmonary hypertension and catecholamine refractory shock. METHODS:This retrospective study was conducted in a level III NICU of a tertiary care teaching hospital, south India. Eighteen neonates with hypoxemic resp...

journal_title：Indian journal of pediatrics

authors： Khare C,Adhisivam B,Bhat BV,Vaishnav D

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVE:To evaluate the use of umbilical cord blood culture (UCBC) as compared to neonatal blood culture (NBC) in the diagnosis of early onset neonatal sepsis (EONS). METHODS:This hospital based prospective observational study was conducted in the Department of Pediatrics and Department of Obstetrics & Gynaecology a...

journal_title：Indian journal of pediatrics

authors： Meena R,Meena KK,Athwani V,Gothwal S,Bairwa GS,Sitaraman S

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To compare oral co-amoxiclav with injectable ampicillin and amikacin for the management of asymptomatic neonates born to mothers with risk factors for infection. METHODS:This open label, randomized controlled trial was conducted in a tertiary care teaching hospital on neonates of gestational age ≥ 34 wk with...

journal_title：Indian journal of pediatrics

authors： Kumar A,Dubey AK,Basu S

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of R501X mutation of Filaggrin gene in children with allergic diseases. METHODS:Ninety patients recruited from Allergy and Asthma clinic of Advanced Pediatric Centre, PGIMER, Chandigarh and 81 healthy controls from local schools matched for age, gender and BMI were enroled in the ...

journal_title：Indian journal of pediatrics

authors： Chauhan A,Panigrahi I,Singh M,Attri SV,Agarwal A,Singh M

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:To highlight different patterns of clinical presentation, share authors' experience in the management of children following button battery ingestion and their outcomes. METHODS:This is a single center descriptive cohort study with a total duration of 5 y (January 2014 through December 2018). Battery removal...

journal_title：Indian journal of pediatrics

authors： Anand S,Jain V,Agarwala S,Dhua AK,Yadav DK

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To assess the need and feasibility of a Transition Clinic in the care of adolescents with chronic illness. METHODS:A qualitative study, piloted by a questionnaire-based survey, followed by Focus Group Discussions was conducted in the Department of Pediatrics in a government teaching hospital in Kerala. The p...

journal_title：Indian journal of pediatrics

authors： Menon J,Peter AM,Nayar L,Kannankulangara A

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To predict the added value of diaphragmatic and lung ultrasound indices (US) in anticipation of the outcome of mechanical ventilation of pediatric patients in the intensive care unit. METHODS:This prospective study was conducted in Zagazig University, Pediatric Hospitals, PICU; Egypt. One hundred six mechani...

journal_title：Indian journal of pediatrics

authors： Abdel Rahman DA,Saber S,El-Maghraby A

更新日期：2020-06-01 00:00:00

abstract：:Developmental co-ordination disorder (DCD) is a hidden complex childhood disorder seen in school aged children. There are only few Indian literatures supporting the prevalence of DCD among Indian school children but this current research has attempted to make a confirmatory diagnosis of DCD. Objective of the study was...

journal_title：Indian journal of pediatrics

authors： Sujatha B,Alagesan J,Lal DV,Rayna ABS

更新日期：2020-06-01 00:00:00

abstract：:Treatment with tyrosine kinase inhibitors (TKI) is an effective therapy for children and adolescents with chronic phase of chronic myeloid leukemia (CML). For the majority of patients with CML in low- and middle-income countries (LMIC), imatinib is the TKI of choice for reasons of cost, availability, and experience. C...

journal_title：Indian journal of pediatrics

authors： Bansal D

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To analyze the infection outbreaks, control measures and outcomes of the outbreak in the NICU of a tertiary care centre in the year 2018. METHODS:This study was conducted in a 30 bedded tertiary care NICU from January 2018 through December 2018. The study design was an Outbreak investigation, based on a prog...

journal_title：Indian journal of pediatrics

authors： Balachander B,Rajesh D,Pinhero CL,Paul S,Stevens S,Rao S

更新日期：2020-05-01 00:00:00

abstract：:Congenital heart diseases have varied presentations depending on the age of presentation. Regression of neonatal pulmonary hypertension and the timing of establishment of left to right shunt determines the onset of symptoms. Pre-tricuspid shunts generally remain asymptomatic during the childhood while large post-tricu...

journal_title：Indian journal of pediatrics

authors： Kannan BR

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects generated by an intensivist in pediatric intensive care unit (PICU) on the process of care and patient outcomes. METHODS:This study was a retrospective observational study conducted in the 16-bedded PICU of a tertiary referral center. Two years (2013-2015) period of the PICU without a...

journal_title：Indian journal of pediatrics

authors： Kesici S,Bayrakci B

更新日期：2020-04-01 00:00:00

abstract：:Pediatric heart failure (PHF) is an important cause of mortality and morbidity. Whereas ischemic heart disease is the most important cause of heart failure in adults, congenital heart diseases (CHD) and cardiomyopathies are important etiologies of PHF. Management of PHF also differs from that of adults. Here authors h...

journal_title：Indian journal of pediatrics

authors： Rohit M,Budakoty S

更新日期：2020-04-01 00:00:00

abstract：:Despite evidence about the value of high quality postnatal services for the survival, health and wellbeing of the mother and neonate, sub-optimal use of the available services delivered through public sector remains a persistent challenge in India and most low-middle income countries. An extensive search till Dec 31, ...

journal_title：Indian journal of pediatrics

authors： Deshmukh V,John S,Arora NK

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:To prospectively study the clinical and developmental profile; hematological profile and the B-12 status using multiple parameters in children with Infantile tremor syndrome (ITS). METHODS:In this observational study (NCT02762682) (July 2015 through December 2016) children (and their mothers) with a clinica...

journal_title：Indian journal of pediatrics

authors： Chaudhary H,Verma S,Bhatia P,Vaidya PC,Singhi P,Sankhyan N

更新日期：2020-03-01 00:00:00

abstract：:The major causes of emergence of multidrug-resistant organisms (MDRO) in neonatal sepsis include empiric antibiotic prescriptions, unregulated use of over-the-counter drugs, high incidence of healthcare associated infections (HAI), lack of awareness about antibiotic stewardship program and under staffing of neonatal i...

journal_title：Indian journal of pediatrics

authors： Wattal C,Kler N,Oberoi JK,Fursule A,Kumar A,Thakur A

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:To screen for variants in the MC4R and LEP genes in 46 patients with clinical suspicion of non-syndromic early onset severe obesity (NEOSO). METHODS:Children with early onset obesity satisfying WHO criteria of obesity were studied. The MC4R and LEP genes were sequenced using a PCR amplicon based NGS on Illu...

journal_title：Indian journal of pediatrics

authors： Khadilkar V,Gogate N,Gangodkar P,Ranade S,Lohiya N,Ragte T,Patil K,Pilankar A,Anand S,Bapat A,Agarwal M,Kaushik K,Lote-Oke R,Khadilkar A,Phadke N

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Hydrocarbons are a common cause of accidental poisoning in children, with kerosene being the most implicated agent in rural parts of India. However, lately, liquid mosquito repellent ingestion is emerging as an important cause of hydrocarbon (kerosene) poisoning in urban households. METHODS:This is a retros...

journal_title：Indian journal of pediatrics

authors： Reddy MV,Ganesan SL,Narayanan K,Jayashree M,Singhi SC,Nallasamy K,Bansal A,Baranwal AK

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the efficacy and safety of nitazoxanide in intestinal parasitic infections in children. METHODS:Four databases, PubMed, EMBASE, Web of Science and Cochrane Library, have been systematically searched from the inception of each database up to March 1st, 2019. The enrolled studies were limited to r...

journal_title：Indian journal of pediatrics

authors： Li J,Kuang H,Zhan X

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Type 1 diabetes (T1D) adolescents often do not achieve good glycemic control. In the context of growing number of technologically savvy adolescents, this study was done to examine the effectiveness of a motivational smartphone app to improve their glycemic control. METHODS:Eleven to eighteen year old adoles...

journal_title：Indian journal of pediatrics

authors： Pramanik BK,Angelin JJ,Mathai VJ,Mathai S,Korula S,Simon A

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y. METHODS:This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from Decem...

journal_title：Indian journal of pediatrics

authors： A J,Ratageri VH,Illalu S,Fattepur SR,Wari PK

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To compare the incidence of hyponatremia during the first 48 h in hospitalized children receiving normal saline vs. N/2 saline as maintenance intravenous fluid. METHODS:This open label, randomized controlled trial to compare the incidence of hyponatremia in hospitalized children receiving normal saline (0.9%...

journal_title：Indian journal of pediatrics

authors： Bagri NK,Saurabh VK,Basu S,Kumar A

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To present evaluation of a quality improvement program for Accredited Social Health Activists (ASHAs). METHODS:This community intervention trial was conducted in Ballabgarh, India during 2012-2014 with two Primary Health Center (PHC) areas being the intervention areas and two PHC areas being non-intervention...

journal_title：Indian journal of pediatrics

authors： Goel AD,Gosain M,Amarchand R,Sharma H,Rai S,Kapoor SK,Krishnan A

更新日期：2019-11-01 00:00:00

abstract：:Microvillous inclusion disease (MVID), also known as congenital microvillus atrophy, was first described by Davidson et al. in 1978. Till date, only a handful of cases with MVID have been described in English literature. It is an autosomal recessive disorder with no sex predisposition and more commonly noted in countr...

journal_title：Indian journal of pediatrics

authors： Phulware RH,Gahlot GPS,Malik R,Gupta SD,Das P

更新日期：2019-09-01 00:00:00

abstract：:Approximately 25,000 children develop multidrug-resistant (MDR) tuberculosis (TB) each year, but few of them are diagnosed and appropriately treated for MDR-TB. New diagnostic tools have improved our ability to diagnose children with bacteriologically confirmed TB earlier. However, the majority of childhood TB cases a...

journal_title：Indian journal of pediatrics

authors： Schaaf HS

更新日期：2019-08-01 00:00:00

abstract：:Most children tolerate the first-line antibiotics used to treat Mycobacterium tuberculosis (TB) very well. The most common adverse effect is gastrointestinal distress unrelated to hepatotoxicity; the latter is seen in less than 1% of children. Despite the infrequency of hepatotoxicity, the potential long-term impact o...

journal_title：Indian journal of pediatrics

authors： Cruz AT,Starke JR

更新日期：2019-08-01 00:00:00

abstract：:Multidrug-resistant tuberculosis (MDR TB) has become a major global health concern and is also an issue in children. Children with MDR TB need longer duration of treatment with multiple drugs. The MDR TB treatment regimen usually comprises of a fluoroquinolone, an aminoglycoside, ethionamide, cycloserine, pyrazinamide...

journal_title：Indian journal of pediatrics

authors： Ramachandran G

更新日期：2019-08-01 00:00:00

abstract：:When a child is diagnosed with epilepsy, counseling regarding the same is done by the treating doctor. Most parents are frightened and have poor knowledge about epilepsy. Therapeutic advice including drug dosage, administration and side effects takes up the major part of physician's time, thereby neglecting important ...

journal_title：Indian journal of pediatrics

authors： Srivastava K,Sehgal R,Konanki R,Jain R,Sharma S,Mittal R,Association of Child Neurology (AOCN)-Indian Epilepsy Society (IES) SOLACE Expert Group.,Hedge A,Aggarwal A,Chattopadhyay A,Patra B,Kaushik JS,Lingappa L,Sankhyan N,Kap

更新日期：2019-07-01 00:00:00

abstract：:High dose vitamin A (HDVA) concentrate began to be distributed in India in 1970 as a short-term, stop-gap approach to reduce clinical signs of vitamin A deficiency. As this problem declined globally, the purpose of distributing them changed to the reduction of young child mortality. However, their impact on this has a...

journal_title：Indian journal of pediatrics

authors： Greiner T,Mason J,Benn CS,Sachdev HPS

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To assess serum sclerostin levels in relation to severity of arthropathy and bone mineral density (BMD) in children with hemophilic arthropathy. METHODS:This cross-sectional study included 40 male children suffering from Hemophilia A, and 10 matched healthy controls. Assessment of factor VIII deficiency degr...

journal_title：Indian journal of pediatrics

authors： El-Mikkawy DME,Elbadawy MA,Abd El-Ghany SM,Samaha D

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Cholestatic jaundice in early infancy is a complex diagnostic challenge. Cholestasis caused by endocrine disease is rare and poorly recognized. The aim of this paper is to report patients with liver dysfunctions resulting from hypopituitarism. METHODS:Six patients with liver dysfunction diagnosed as hypopitu...

journal_title：Indian journal of pediatrics

authors： Altay D,Eren E,Ozkan TB,Ozgur T,Tarım O

更新日期：2019-05-01 00:00:00