解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:Ginsenosides, biologically-active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardized commercial ginseng extract, G115®, could...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2021.2
更新日期:2021-01-22 00:00:00
abstract:OBJECTIVE:To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour in young animals exposed to maternal immune activation (MIA). METHODS:To this aim, on the 15th gestational day, the females received an injection of lipopolysaccharides. Whe...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2020.27
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To investigate how individuals with a history of affective disorder use and perceive their use of social media and online dating. METHODS:A questionnaire focusing on affective disorders and the use of social media and online dating was handed out to outpatients from unipolar depression and bipolar disorder ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2020.36
更新日期:2020-10-15 00:00:00
abstract:BACKGROUND:Encephalitis due to anti-N-methyl-D-aspartate receptor antibodies (ANMDARE) is the most frequent immune-mediated encephalitis. It is distinguished by the subacute onset of neuropsychiatric symptoms. OBJECTIVE:To evaluate the characteristic neuropsychiatric symptoms and their outcome in patients diagnosed wi...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2019.46
更新日期:2020-04-01 00:00:00
abstract::In two previous letters on an selective serotonin reuptake inhibitor (SSRI) meta-analysis conducted by the Copenhagen Trial Unit at Copenhagen University Hospital, we have commented on a large number of errors, almost all of which have tilted the results in an anti-drug direction, that unfortunately mar this publicati...
journal_title:Acta neuropsychiatrica
pub_type: 评论,杂志文章
doi:10.1017/neu.2019.42
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM). METHODS:We performed a VBM study using a 3Т MRI system (GE Discovery 750...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2019.20
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:Inverse relationships between the C-reactive protein (CRP) levels and cognitive performance in acute psychosis have been demonstrated. We aimed to investigate how the serum level and initial change of CRP in acutely admitted patients with psychosis was correlated with cognitive performance during a 6-months f...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2018.25
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To investigate oxidative stress parameters [total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase (PON), arylesterase (ARE) and thiol-disulphide homeostasis] in patients who were diagnosed as having somatic symptom disorder in accordance with Diagnostic and Stat...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2018.33
更新日期:2018-12-18 00:00:00
abstract:OBJECTIVE:This study aimed to explore effects of adjunctive treatment with N-acetyl cysteine (NAC) on markers of inflammation and neurogenesis in bipolar depression. METHODS:This is a secondary analysis of a placebo-controlled randomised trial. Serum samples were collected at baseline, week 8, and week 32 of the open-...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章,随机对照试验
doi:10.1017/neu.2018.13
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2018.4
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of transcranially applied pulsed electromagnetic fields (PEMF) on functional impairments and symptom severity in multiple chemical sensitivity (MCS) patients. METHODS:The study was conducted as a nationwide trial in Denmark using a randomised, parallel-group, double-blind and placebo...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章,随机对照试验
doi:10.1017/neu.2016.51
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:Post-traumatic stress disorder (PTSD) displays high co-morbidity with major depression and treatment-resistant depression (TRD). Earlier work demonstrated exaggerated depressive-like symptoms in a gene×environment model of TRD and an abrogated response to imipramine. We extended the investigation by studying ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2016.50
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2016.49
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic i...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.58
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:Disturbances in the noradrenergic system, including alterations in the densities of α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this study, we investigate the binding of α2-adrenoceptors in regions relevant to depression in an animal model of depression. METHODS:Usi...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.24
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Attention-deficit hyperactivity disorder (ADHD) is a chronic neurobiological disorder with childhood onset and persistence through adolescence and adulthood. ADHD patients frequently show exaggerated emotional responses. The amygdala plays an important role in emotion processing and in the activation of the ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.34
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Prisoners categorised as 'dangerous' are a category of prisoners that require and/or force into using special measures of caution, protection and security. The aim of the study was to examine the intensity of anxiety (as a state and as a trait) experienced by officers working with 'dangerous' prisoners and st...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.31
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to analyse demographic and clinical characteristics, as well as psychiatric diagnoses to identify gender differences in patients with attempted suicide in a Mexican population. METHODS:Between September 2010 and September 2012, 140 suicide attempts were documented in the Depa...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.6
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:We investigated whether the nitric oxide (NO) precursor, L-arginine, can prevent the antidepressant-like action of the fast-acting antidepressant, ketamine, in a genetic rat model of depression, and/or induce changes in the glutamate (Glu)/N-methyl-D-aspartate receptor (NMDAR)/NO/cyclic guanosine monophosphat...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2014.39
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Shared decision making (SDM) is an essential component of patient-centered care, but there is little information about its use in the psychiatric care. OBJECTIVE:To measure to what extent psychiatric patients feel they were involved in the process and steps of decision making about treatment choice and to a...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2014.21
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:Brain-derived neurotrophic factor (BDNF) and S100B are involved in brain plasticity processes and their serum levels have been demonstrated to be altered in patients with psychoses. This study aimed to identify subgroups of patients with psychotic disorders across diagnostic boundaries that show a specific sy...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.59
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:Mazindol is a sympathomimetic amine, widely used as an anorectic agent in the treatment of obesity. This drug causes psychostimulant effects because of its pharmacological profile similar to amphetamine, acting like a monoamine reuptake inhibitor. However, the mechanisms underlying the action of mazindol are...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.43
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:Schizoaffective disorder is a disease with both affective and psychotic symptoms. In this study, we aimed to compare oxidative metabolism markers of schizoaffective disorder, bipolar disorder and schizophrenic patients. Furthermore, we also aimed to investigate whether schizoaffective disorder could be differ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.44
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Stress can stimulate increased production of oxygen radicals. We investigated the correlations between serum levels of lipid peroxidation markers and those in brain samples in different stress models. METHODS:Animals (n = 96) were divided equally into eight groups: a control group and groups treated with vit...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.32
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.7
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging. METHODS:We report a case with an initially typical severe depressive episode without any focal neurological deficits. RESULTS:Only medical history from a t...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.19
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To investigate gender differences in psychiatric comorbidity patients diagnosed with attention-deficit hyperactivity disorder (ADHD) as adults. METHODS:Interviews about current ADHD symptoms and psychiatric comorbidity on axis I and II (Structured Clinical Interview for DSM-IV axis I and axis II) were conduc...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2012.00682.x
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Bacterial meningitis is an infection of the central nervous system characterised by strong inflammatory response. The brain is highly dependent on ATP, and the cell energy is obtained through oxidative phosphorylation, a process which requires the action of various respiratory enzyme complexes and creatine k...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2012.00671.x
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:Typical and atypical antipsychotic drugs have been shown to have different clinical, biochemical and behavioural profiles. It is well described that impairment of metabolism, especially in the mitochondria, leads to oxidative stress and neuronal death and has been implicated in the pathogenesis of a number of...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2012.00650.x
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Fas (CD95), commonly categorised as a death receptor due to its well-defined role in apoptosis, can paradoxically also promote neuroprotection. We have previously found that defects in Fas signalling render mice highly susceptible to neural degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mous...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00615.x
更新日期:2012-06-01 00:00:00
abstract::BACKGROUND: Yoga therapy (YT) improves cognitive function in healthy individuals, but its impact on cognitive function among persons with schizophrenia (SZ) has not been investigated. AIMS: Evaluate adjunctive YT for cognitive domains impaired in SZ. METHODS: Patients with SZ received YT or treatment as usual (TAU; ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00587.x
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:There is clear evidence of a genetic component in major depression, and several studies indicate that neuropeptide Y (NPY) could play an important role in the pathophysiology of the disease. A well-known polymorphism encoding the substitution of leucine to proline in the signal peptide sequence of NPY (Leu7Pr...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00600.x
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:The mechanisms involved in the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, especially in the functioning of glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) in depressed patients, are not well elucidated. The objective of this study was to conduct a systematic review of art...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00610.x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVES:Depression and dementia are highly prevalent in the elderly. Language impairment is an inherent component of Alzheimer's disease (AD), which can also be encountered in depressed patients. The aim of this study wasto compare the profiles of language abilities in late-onset depression and mild AD groups. METH...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00526.x
更新日期:2011-04-01 00:00:00
abstract:UNLABELLED:Jones MP, Bartrop RW, Forcier L, Penny R. The long-term impact of bereavement upon spouse health: a 10-year follow-up. OBJECTIVES:This study is the first to examine the effect of bereavement of a first-degree family member on subsequent morbidity over a 10-year follow-up period. METHODS:A sample of bereave...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2010.00482.x
更新日期:2010-10-01 00:00:00
abstract::BACKGROUND: Aberrant electrophysiological and hemodynamic processing of auditory oddball stimuli is among the most robustly documented findings in patients with schizophrenia. However, no study to date has directly examined linked patterns of electrical and hemodynamic differences in patients and controls. METHODS: I...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2010.00467.x
更新日期:2010-06-01 00:00:00
abstract:UNLABELLED:Scheuch K, Bräunig P, Gauggel S, Kliesow K, Sarkar R, Krüger S. Emotional vulnerability and cognitive control in patients with bipolar disorder and their healthy siblings: a pilot study. OBJECTIVE:There is evidence that, even in remission, patients with bipolar disorder (BD) have deficits in cognitive funct...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2010.00451.x
更新日期:2010-04-01 00:00:00
abstract::In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2009.00414.x
更新日期:2009-10-01 00:00:00
abstract::In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:
更新日期:2009-09-23 00:00:00
abstract:OBJECTIVE:This study used a prospective design and the technique of structural modelling to examine the complex interrelations between psychological factors, immune status and complications after major surgery. METHODS:Twenty-nine women scheduled for elective cholecystectomy were studied prospectively. Information reg...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2009.00398.x
更新日期:2009-08-01 00:00:00