abstract：BACKGROUND:In the German guidelines for prophylaxis of group B streptococcal (GBS) early onset sepsis in neonates (EOS), GBS screening of all pregnant women has been recommended, but is not yet included in the Maternity Directives. Aim of the study was to identify temporal trends in incidence of EOS and their associati...

journal_title：Klinische Padiatrie

authors： Sorg AL,Obermeier V,Armann J,Klemme M,von Kries R

更新日期：2021-01-01 00:00:00

abstract：AIM:Reports describing coronavirus disease 2019 (Covid-19) in children are fewer than adult studies due to milder clinical picture. We aimed to share our experience at a single center with an emphasis on collective decision making. MATERIALS AND METHODS:A suspected case was defined as the presence of symptoms suggesti...

journal_title：Klinische Padiatrie

authors： Duramaz BB,Turel O,Korkmaz C,Karadogan MT,Yozgat CY,Iscan A,Sümbül B,Erenberk U

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The medical care of pediatric cancer patients in the German health care system relies on special structures. All children and adolescents with a diagnosis of cancer receive uniform treatment within clinical studies or registers and exclusively at centers which can ensure interdisciplinary care by a multiprof...

journal_title：Klinische Padiatrie

authors： Reinke E,Jürgens H,Haier J,Froehlich B,Kontny U,Rossig C

更新日期：2020-11-01 00:00:00

abstract：:Easier access to prenatal diagnostic procedures led to its widespread use as a screening measure. Hence, today it is more common for life-limiting illnesses to be diagnosed during fetal life. The concept of Advance Care Planning (ACP) provides a framework for caregivers, families and their multidisciplinary teams to a...

journal_title：Klinische Padiatrie

authors： Garten L,von der Hude K,Strahleck T,Krones T

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:  Despite a reduction in hospitalizations due to acute alcohol intoxication in minors, alcohol consumption among children and adolescents still presents an alarming social and clinical phenomenon. This is amplified by presumably more severe clinical symptoms of the alcohol intoxication in children and adoles...

journal_title：Klinische Padiatrie

authors： Lozada CAQ,Bartels MB,Kieslich M

更新日期：2020-09-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a systemic inflammatory disorder characterized by uncontrolled histiocytic proliferation, hemophagocytosis, macrophage activation, and up-regulation of inflammatory cytokines (Grom AA., Current opinion in rheumatology 2003; 15: 587-590). HLH is usually divided into two types...

journal_title：Klinische Padiatrie

authors： Li Y,Wang Y,Li S,Liu M,Wang D,Xu C,Zhang L

更新日期：2020-02-25 00:00:00

abstract：INTRODUCTION:Gender dysphoria (GD) in childhood and adolescence is characterized by an incongruence between sex at birth and gender identity, which usually increases during puberty. Gender dysphoric children and adolescents often suffer from psychological comorbidities such as depression. The purpose of our study is to...

journal_title：Klinische Padiatrie

authors： Specht AA,Gesing J,Pfaeffle R,Koerner A,Kiess W

更新日期：2020-01-01 00:00:00

abstract：:Central nervous system (CNS) tumors account for the highest mortality among pediatric malignancies. Accurate diagnosis is essential for optimal clinical management. The increasing use of molecular diagnostics has opened up novel possibilities for more precise classification of CNS tumors. We here report a single-insti...

journal_title：Klinische Padiatrie

authors： Bächli H,Ecker J,van Tilburg C,Sturm D,Selt F,Sahm F,Koelsche C,Grund K,Sutter C,Pietsch T,Witt H,Herold-Mende C,von Deimling A,Jones D,Pfister S,Witt O,Milde T

更新日期：2018-10-01 00:00:00

abstract：HINTERGRUND: Die zeitliche Verzögerung zwischen Symptombeginn und Diagnose ist eine Herausforderung in der Behandlung von Kindern mit arteriell ischämischem Schlaganfall. Frühere Studien zur klinischen Präsentation beschäftigten sich v. a. mit kumulativen Symptomen. ZIELSETZUNG: Ziel dieser Studie ist es, mögliche Sym...

journal_title：Klinische Padiatrie

authors： Gerstl L,Weinberger R,von Kries R,Heinen F,Sebastian Schroeder A,Veronika Bonfert M,Borggräfe I,Tacke M,Vill K,N Landgraf M,Kurnik K,Olivieri M

更新日期：2018-10-01 00:00:00

abstract：:Die Fortschritte der molekularen Diagnostik haben neue Türen für die Diagnosestellung, Risikostratifizierung und Präzisionsonkologie für Kinder mit Hirntumoren aufgestoßen. Dieses Wissen konsequent und systematisch in einen klinischen Nutzen zu übertragen wird Aufgabe der kommenden Jahre sein. ...

journal_title：Klinische Padiatrie

authors： Milde T,Witt O

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Congenital heart disease is the most common cause of major congenital anomalies. After prenatal diagnosis effective counseling is crucial. However, little research has been undertaken in determining the most effective techniques. OBJECTIVES:To develop a questionnaire suitable to assess parental needs for co...

journal_title：Klinische Padiatrie

authors： Kovacevic A,Simmelbauer A,Starystach S,Elsässer M,Sohn C,Müller A,Bär S,Gorenflo M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Acute viral bronchiolitis is a frequent disease in infancy. There is little knowledge on medical care of severely affected infants in different European countries. PATIENTS:Infants (n=146) with bronchiolitis requiring respiratory support in winter season 2015/2016 treated in either one of two regions in Cen...

journal_title：Klinische Padiatrie

authors： Dohna-Schwake C,Mücher K,Stehling F,Rothoeft T,Roll C,Brevis Nuńez F,Seiffert P,Heister P,Hofmann M,Stein A,Jacobs A,Zuzak T,Durand P,Felderhoff-Müser U,Tissières P

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Transumbilical laparoscopic-assisted appendectomy (TULAA) is fast and cost-effective since no endoloops, staplers or wound protection devices are used. We analyzed the effects of TULAA as first approach for perforated (PA) and non-perforated (NPA) appendicitis in children. PATIENTS:We performed a retrospect...

journal_title：Klinische Padiatrie

authors： Dübbers M,Nikolaou E,Fuchs H,Fischer J,Alakus H,Leers J,Bruns C,Cernaianu G

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Thermal injuries are a frequent cause of accidents within the pediatric population that may result in long periods of hospitalization as well as severe physical and mental impairment and lifelong consequences. Especially in infants, burns caused by scalding are the most common cause of injury. Beside acciden...

journal_title：Klinische Padiatrie

authors： Klinke M,Schmidt CM,Tegtmeyer L,Reinshagen K,Boettcher M,Koenigs I

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Due to rising survival rates in cancer and autoimmune diseases fertility preservation before gonadotoxic therapies has become increasingly important. Although fertility can be significantly affected by gonadotoxic therapies, the possibility of fertility preservation during childhood has not been sufficiently...

journal_title：Klinische Padiatrie

authors： Sänger N,Jarisch A,Ochsendorf F,Klingebiel T,Liebenthron J,Kliesch S,von Wolff M

更新日期：2018-02-08 00:00:00

abstract：:Purpose To determine the population prevalence and risk factors of myopia in children and adolescents in Germany. Methods The prevalence of myopia in Germany was computed using data from the 2003-2006 German Health Interview and Examination Survey for Children and Adolescents (N=17 640, 49% girls). Status of myopia wa...

journal_title：Klinische Padiatrie

authors： Schuster AK,Elflein HM,Pokora R,Urschitz MS

更新日期：2017-07-01 00:00:00

abstract：:Background: Transient synovitis is the most common hip joint disorder in children. Perthes disease occurs around the same age and may not be distinguishable to an episode of transient synovitis in the early stage. Therefore all children in our clinic with transient synovitis underwent a follow-up X-ray 3 months later ...

journal_title：Klinische Padiatrie

authors： Lenoir U,Slongo T,Aghayev E,Joeris A

更新日期：2017-03-01 00:00:00

abstract：:Background For the new cystic fibrosis (CF) newborn screening program in Germany the Federal Joint Committee (G-BA) implemented a new screening protocol using immunoreactive trypsinogen (IRT) as first and pancreatitis associated protein (PAP) as second tier. Gene analysis with a panel of 31 CFTR-mutations is used as t...

journal_title：Klinische Padiatrie

authors： Sommerburg O,Stahl M,Hammermann J,Okun JG,Kulozik A,Hoffmann G,Mall M

更新日期：2017-03-01 00:00:00

abstract：:Infants exposed to opiates antenatally display withdrawal symptoms after birth referred to as neonatal abstinence syndrome (NAS).A total of 366 newborns (166 females, 10 twins) from 361 mothers were diagnosed with NAS from 2000 to 2011 at a single large metropolitan referral center.Retrospective chart review of all ne...

journal_title：Klinische Padiatrie

authors： Mücke S,Nagel M,Siedentopf J,Bührer C,Hüseman D

更新日期：2017-01-01 00:00:00

abstract：:Objective: Toilet refusal syndrome (TRS) is a common disorder in toddlers, defined by use of diapers and refusal of toilet for defecation, while toilet phobia (TP) is a rare disorder in which toilets are avoided completely. Both disorders have not been described systematically in children, yet. Therefore, the aim was ...

journal_title：Klinische Padiatrie

authors： Wagner C,Niemczyk J,von Gontard A

更新日期：2017-01-01 00:00:00

abstract：:Background: Diabetes mellitus is a common endocrinopathy in patients with thalassemia major, but the occurrence of hemoglobinopathies is rare in Germany and Western Europe. The longitudinal German-Austrian DPV (Diabetes Patienten Verlaufsdokumentation) registry allows a comprehensive characterization of this group of ...

journal_title：Klinische Padiatrie

authors： Warncke K,Konrad K,Kohne E,Hammer E,Ohlenschläger U,Herrlinger S,Jäger A,Holl RW

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To identify obstetric and neonatal risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) in high-risk preterm neonates. METHODS AND PATIENTS:Data from 279 preterm infants (246 mothers) with a gestational age≤28+0 weeks admitted to our NICU between January 2004 a...

journal_title：Klinische Padiatrie

authors： Waitz M,Nusser S,Schmid MB,Dreyhaupt J,Reister F,Hummler H

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Marked progress in neonatology changed care of very preterm infants (VLBW) over the last decades - but also the attitude towards family-centred care (FCC). With the directive of the German Federal Joined Committee (G-BA), politicians recognize the necessity of neonatal FCC. AIM:To evaluate time and personne...

journal_title：Klinische Padiatrie

authors： Hüning BM,Reimann M,Sahlmen S,Leibold S,Nabring JC,Felderhoff-Müser U

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The prevalence of asthma and overweight/obesity in children and adolescents is continuously increasing over the last decades. It remains unclear if overweight/obesity raises the risk of developing asthma or if an uncontrolled asthma increases the risk of developing overweight/obesity by restricting physical ...

journal_title：Klinische Padiatrie

authors： Schmauck-Gómez JS,Menrath I,Kaiser MM,Herz A,Kopp MV

更新日期：2016-07-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a rare malignant tumor arising from epithelial cells of the nasopharynx. Its incidence is highest in Southeast Asia. Age distribution of NPC is bimodal, with one peak in young adolescents and another in patients 55-59 years of age. EBV appears to be the primary etiologic agent in the ...

journal_title：Klinische Padiatrie

authors： Kontny U,Franzen S,Behrends U,Bührlen M,Christiansen H,Delecluse H,Eble M,Feuchtinger T,Gademann G,Granzen B,Kratz CP,Lassay L,Leuschner I,Mottaghy FM,Schmitt C,Staatz G,Timmermann B,Vorwerk P,Wilop S,Wolff HA,Mer

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Autism spectrum disorders (ASDs) are a group of developmental disabilities in childhood and adolescence. Beside genetic predisposition also environmental influences may contribute to the ASD pathogenesis. Family members of children and adolescents with ASD often ask for specific diets to alleviate ASD-associ...

journal_title：Klinische Padiatrie

authors： Sausmikat J,Smollich M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Disproportionate short stature may impair the quality of life (QoL) of patients and their families. This study aimed to evaluate a self-help supported counseling concept to increase the QoL of the participants. METHODS:QoL data from 58 children/adolescents (8-17 years) with a diagnosis of achondroplasia was...

journal_title：Klinische Padiatrie

authors： Rohenkohl AC,Sommer R,Kahrs S,Bullinger M,Klingebiel KH,Quitmann JH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Children suffering from life limiting diseases are frequently cared for by adult palliative care teams due to missing paediatric structures in that field. However it is questionable whether palliative care curricula for physicians comprehensively cover issues of paediatric palliative care (PaedPC). AIM:To i...

journal_title：Klinische Padiatrie

authors： Schiessl C,Gottschling S,Gronwald BM

更新日期：2016-01-01 00:00:00

abstract：:This case report describes the forensic examination of 7 girls aged between 4-11 years with suspected sexual abuse. The children had been reported by local pediatricians, hospital physicians or authorities such as the youth welfare office and police due to mucosal changes in the anogenital area. All children presented...

journal_title：Klinische Padiatrie

authors： Navarro-Crummenauer B,Pickhardt CP,Urban R

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:A fast and comprehensive diagnostic by means of whole-body CT has been shown to reduce mortality in the adult trauma population. Therefore whole-body CT seems to be the standard in adult trauma-patients. Due to the higher radiation exposure of whole-body CT the use of this diagnostic toll in pediatric trauma...

journal_title：Klinische Padiatrie

authors： Hilbert-Carius P,Hofmann GO,Lefering R,Stuttmann R,Bucher M,Goebel P,Gronwald GH

更新日期：2015-07-01 00:00:00

abstract：:In Germany, about 1,800 new cases of childhood cancer are diagnosed every year. The chances of survival have increased significantly over the last 40 years due to the continuous improvement of treatment strategies. The number of childhood cancer survivors in Germany thus ranges around 30,000 nowadays. But their treatm...

journal_title：Klinische Padiatrie

authors： Kock AK,Kaya RS,Müller C,Andersen B,Langer T,Ingenerf J

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:After a first afebrile seizure, EEG in addition to cMRI is recommended for pediatric patients. Once indications requiring immediate treatment are excluded, it is of interest to determine if the results provide a prognostic tool for seizure relapses. METHODS:Patients aged between 1 month and 18 years who had...

journal_title：Klinische Padiatrie

authors： Tews W,Weise S,Syrbe S,Hirsch W,Viehweger A,Merkenschlager A,Bertsche A,Kiess W,Bernhard MK

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:For quick detection of neonatal early-onset bacterial infection (EOBI) pro-inflammatory cytokines like Interleukin-6 (IL-6) and Interleukin-8 (IL-8) in combiantion with C-reactive Protein (CRP) have been used. Automated determination of immature myeloid information (IMI) seems to be an additional useful tool...

journal_title：Klinische Padiatrie

authors： Neunhoeffer F,Dabek MT,Renk H,Rimmele P,Poets C,Goelz R,Orlikowsky T

更新日期：2015-03-01 00:00:00

abstract：:The pros and cons of home monitoring especially for premature infants with continuing apneic episodes and/or chronic lung disease are an ongoing discussion. The controversy spans socio-economic requirements, medical indication as well as patient and family needs. Here, the costs of home monitoring and follow-up care o...

journal_title：Klinische Padiatrie

authors： Förster KM,Immler S,Ensslen M,Flemmer A,Schulze A,von Poblotzki M,Genzel-Boroviczény O,Heinen F,Hilgendorff A

更新日期：2015-03-01 00:00:00

abstract：:The therapy of complicated Kaposiform hemangioendothelioma (KHE) is still difficult. We present the first case of laryngomalacia with simultaneous mammalian target of Rapamycin (mTOR)-positive KHE of the neck and thoracic inlet and concurrent Kasabach-Meritt Phenomenon (KMP) in an 11-month-old boy suffering life-threa...

journal_title：Klinische Padiatrie

authors： Schroeder U,Lauten M,Stichtenoth G,Gebhard MP,Buchholz M,Kaiser MM

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:Sickle cell disease is a chronic hematologic disease with variable but often severe systemic symptoms. In this report, we describe a 6-year-old boy presenting with acute bowel pseudo-obstruction. During this episode, previously undiagnosed sickle cell disease was discovered upon peripheral blood smear analys...

journal_title：Klinische Padiatrie

authors： Knorr M,Bienemann K,Walde G,Kaufhold A,Schündeln MM

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:After corrective surgery for congenital heart defects (CHD) many patients suffer from residual defects, some with reduced cardiorespiratory capacity and possible impairment of their health related quality of life (HRQoL). The aim of our study is to evaluate, how children after surgery for CHD rate their HRQo...

journal_title：Klinische Padiatrie

authors： Heusch A,Calaminus G,Kahl J,Schmidt K

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Current resuscitation guidelines recommend the use of simulation-based medical education (SBME) as an instructional methodology to improve patient safety and health. We sought to investigate the evidence-base for the effectiveness of SBME for neonatal and pediatric resuscitation training. METHOD:Therefore, ...

journal_title：Klinische Padiatrie

authors： Mileder LP,Urlesberger B,Szyld EG,Roehr CC,Schmölzer GM

更新日期：2014-09-01 00:00:00

abstract：:Interdisciplinary cooperation and networking determine the success of activities for supporting families at risk for early childhood abuse. The integration of the healthcare sector might be important.The medical standard of perinatal care at the University hospital includes information exchange about family risk facto...

journal_title：Klinische Padiatrie

authors： Clauß D,Deutsch J,Krol I,Haase R,Willard P,Müller-Bahlke T,Mauz-Körholz C,Körholz D

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Drug handling in paediatric intensive care units (PICU) is prone to medication errors. We aimed to identify type and prevalence of those errors and to assess preventative interventions. METHODS:Prospective intervention study investigating a 3-step intervention for preventing errors in drug handling in a 10-...

journal_title：Klinische Padiatrie

authors： Niemann D,Bertsche A,Meyrath D,Oelsner S,Ewen AL,Pickardt B,Henhapl T,Hoffmann G,Meyburg J,Bertsche T

更新日期：2014-04-01 00:00:00